Photo of Sean B. Orenstein, M.D., F.A.C.S.

Sean B. Orenstein M.D., F.A.C.S.

    • Assistant Professor of Surgery, Division of Gastrointestinal and General Surgery School of Medicine

Dr. Orenstein joined the OHSU Department of Surgery in 2014 as Assistant Professor of Surgery within the Division of Gastrointestinal and General Surgery.  His research interests include outcomes and improvements for minimally invasive and open hernia repair techniques, evaluation of hernia mesh prosthetics, and further exploration of the fusion between endoscopic and surgical techniques to improve patient outcomes and medical care.

Dr. Orenstein's residency and fellowship training allowed him to explore his passion for hernia repair, with specialized training in abdominal wall reconstruction for complex and recurrent abdominal hernias. During his fellowship he also focused on minimally invasive surgical techniques such as laparoscopic hernia repair, laparoscopic foregut surgery, and laparoscopic diaphragmatic pacemaker placement for Amyotrophic Lateral Sclerosis (ALS) or spinal cord injury. His fellowship was also an avenue to receive specialized training on advanced endoscopy, including per oral endoscopic myotomy (POEM) for achalasia, endoscopic retrograde cholangiopancreatography (ERCP), and endoscopic stenting.

Dr. Orenstein has held membership with the Association for Academic Surgery since 2008, and with the American College of Surgeons, Americas Hernia Society, and the Society of American Gastrointestinal and Endoscopic Surgeons since 2009.

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Areas of interest

  • Hernia repair
  • Abdominal Wall Reconstruction (AWR)
  • Minimally Invasive Surgery
  • Robotic-assisted Surgery
  • Gastrointestinal (GI) Surgery
  • General Surgery

Education

  • B.A., University of Colorado, Boulder Colorado United States 1999
  • M.M.S., MCP Hahnemann University, Philadelphia Pennsylvania United States 2002
  • M.D., Albany Medical College, Albany New York United States 2006
  • Residency:

    • General Surgery, University of Connecticut School of Medicine, Farmington and Hartford, CT, 2006-2013
  • Fellowship:

    • Advanced GI and Minimally Invasive Surgery, University Hospitals Case Medical Center, Cleveland, OH, 2013-2014
  • Certifications:

    • American Board of Surgery, 2015

Memberships and associations

  • American College of Surgeons (ACS)
  • Americas Hernia Society (AHS)
  • Society of American Gastrointestinal and Endoscopic Surgeons (SAGES)
  • Association for Academic Surgery (AAS)

Publications

  • "Activation of human mononuclear cells by porcine biologic meshes in vitro" Hernia : the journal of hernias and abdominal wall surgery August 2010
  • "Central failures of lightweight monofilament polyester mesh causing hernia recurrence" Hernia : the journal of hernias and abdominal wall surgery February 1 2015
  • "Human monocyte activation by biologic and biodegradable meshes in vitro" Surgical Endoscopy and Other Interventional Techniques April 2010
  • "Repair of massive ventral hernias with “quiltedâ€� mesh" Hernia : the journal of hernias and abdominal wall surgery April 9 2015
  • "Real-time cadaveric laparoscopy and laparoscopic video demonstrations in gross anatomy" The American surgeon January 1 2015
  • "Anisotropic evaluation of synthetic surgical meshes" Hernia : the journal of hernias and abdominal wall surgery February 2011
  • "Transversus abdominis muscle release" American Journal of Surgery November 2012
  • "Comparative analysis of histopathologic responses to implanted porcine biologic meshes" Hernia : the journal of hernias and abdominal wall surgery September 28 2014
  • "Laparoscopic placement of adjustable gastric band in patients with autoimmune disease or chronic steroid use" Obesity Surgery  2014
  • "Risk factors for wound morbidity after open retromuscular (sublay) hernia repair" Surgery (United States) December 1 2015
  • "Retrograde myotomy" Surgical Endoscopy and Other Interventional Techniques October 21 2014
  • "Advantages of the hand-assisted versus the open approach to elective colectomies" Surgical Endoscopy and Other Interventional Techniques May 2011
  • "In Vitro Activation of Human Peripheral Blood Mononuclear Cells Induced by Human Biologic Meshes1 " Journal of Surgical Research January 2010
  • "Comparative analysis of histopathologic effects of synthetic meshes based on material, weight, and pore size in mice" Journal of Surgical Research August 2012
  • "Evaluation of serum cytokine release in response to hand-assisted, laparoscopic, and open surgery in a porcine model" American Journal of Surgery July 2011
  • "Transversus abdominis muscle release for repair of complex incisional hernias in kidney transplant recipients" American Journal of Surgery August 1 2015
  • "Effect of patient and hospital characteristics on outcomes of elective ventral hernia repair in the United States" Hernia : the journal of hernias and abdominal wall surgery  2013
  • "Effects of mast cell modulation on early host response to implanted synthetic meshes" Hernia : the journal of hernias and abdominal wall surgery October 2010
  • "Outcomes of laparoscopic ventral hernia repair with routine defect closure using "shoelacing" technique" Surgical Endoscopy and Other Interventional Techniques May 2011
  • "Technical aspects of bile duct evaluation and exploration" Surgical Clinics of North America  2014
  • "Laparoscopic-Assisted Drainage of a Massive Retroperitoneal Abscess Caused by Group B Streptococcus" Surgical Infections February 1 2015
  • "Peroral endoscopic myotomy (POEM) leads to similar results in patients with and without prior endoscopic or surgical therapy" Surgical Endoscopy and Other Interventional Techniques April 8 2015
  • "Small bowel obstruction owing to displaced spiral tack after laparoscopic TAPP inguinal hernia repair" Surgical Laparoscopy, Endoscopy and Percutaneous Techniques June 2010
  • "Ventral Hernia Management" Annals of Surgery March 15 2016
  • "Outcomes of Posterior Component Separation With Transversus Abdominis Muscle Release and Synthetic Mesh Sublay Reinforcement" Annals of Surgery February 19 2016
  • "Percutaneous endoscopic gastrostomy"  January 1 2016
  • "Stapled Transabdominal Ostomy Reinforcement with retromuscular mesh (STORRM)" American Journal of Surgery  2017
  • "Laparoscopic ventral hernia repair with defect closure"  June 11 2016
  • "Sarcopenia and outcomes in ventral hernia repair" Hernia : the journal of hernias and abdominal wall surgery May 11 2018
  • "Abdominal wall reconstruction risk stratification tools" Plastic and Reconstructive Surgery September 1 2018

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