Photo of Mary L. Wirtz, Ph.D.

Mary L. Wirtz Ph.D.

    • Research Associate Professor of Ophthalmology School of Medicine
    • Molecular Microbiology and Immunology Graduate Program School of Medicine
    • Program in Molecular and Cellular Biosciences School of Medicine

Publications

  • "Consensus recommendations for trabecular meshwork cell isolation, characterization and culture." Experimental Eye Research  In: , Vol. 171, 01.06.2018, p. 164-173.
  • "Working your SOCS off : The role of ASB10 and protein degradation pathways in glaucoma." Experimental Eye Research  In: , 02.03.2016.
  • "The role of the IL-20 subfamily in glaucoma." Mediators of Inflammation  In: , Vol. 2016, 4083735, 2016.
  • "Interleukin-20 receptor expression in the trabecular meshwork and its implication in glaucoma." Journal of Ocular Pharmacology and Therapeutics  In: , Vol. 30, No. 2-3, 01.03.2014, p. 267-276.
  • "Glaucoma risk factors : Family history – the genetics of glaucoma."   Clinical Glaucoma Care: The Essentials. Springer New York, 2014. p. 45-56.
  • "Ankyrin repeat and suppressor of cytokine signaling box containing protein-10 is associated with ubiquitin-mediated degradation pathways in trabecular meshwork cells." Molecular Vision  In: , Vol. 19, 25.07.2013, p. 1639-1655.
  • "Variants in ASB10 are associated with open-angle glaucoma." Human Molecular Genetics  In: , Vol. 21, No. 6, ddr572, 03.2012, p. 1336-1349.
  • "Microenvironmental regulation by fibrillin-1." PLoS Genetics  In: , Vol. 8, No. 1, e1002425, 01.2012.
  • "The path to open-angle glaucoma gene discovery : Endophenotypic status of intraocular pressure, cup-to-disc ratio, and central corneal thickness." Investigative Ophthalmology and Visual Science  In: , Vol. 51, No. 7, 07.2010, p. 3509-3514.
  • "Association of POAG risk factors and the Thr377met MYOC mutation in an isolated greek population." Investigative Ophthalmology and Visual Science  In: , Vol. 51, No. 6, 06.2010, p. 3055-3060.
  • "Primary open angle glaucoma due to T377M MYOC : Population mapping of a Greek founder mutation in Northwestern Greece." Clinical Ophthalmology  In: , Vol. 4, No. 1, 2010, p. 171-178.
  • "Myocilin variations and familial glaucoma in Taxiarchis, a small Greek village." Molecular Vision  In: , Vol. 14, 25.04.2008, p. 774-781.
  • "Clinical Features Associated With an Asp380His Myocilin Mutation in a US Family With Primary Open-Angle Glaucoma." American Journal of Ophthalmology  In: , Vol. 144, No. 1, 07.2007.
  • "Differential expression profile prioritization of positional candidate glaucoma genes : The GLC1C locus." Archives of Ophthalmology  In: , Vol. 125, No. 1, 01.2007, p. 117-127.
  • "Investigation of founder effects for the Thr377Met Myocilin mutation in glaucoma families from differing ethnic backgrounds." Molecular Vision  In: , Vol. 13, 2007, p. 487-492.
  • "A large GLC1C Greek family with a myocilin T377M mutation : Inheritance and phenotypic variability." Investigative Ophthalmology and Visual Science  In: , Vol. 47, No. 2, 02.2006, p. 620-625.
  • "The role of the WDR36 gene on chromosome 5q22.1 in a large family with primary open-angle glaucoma mapped to this region." Archives of Ophthalmology  In: , Vol. 124, No. 9, 2006, p. 1328-1331.
  • "Refining the primary open-angle glaucoma GLC1C region on chromosome 3 by haplotype analysis." Clinical Genetics  In: , Vol. 65, No. 1, 01.2004, p. 40-44.
  • "The genetic loci of open-angle glaucoma." Ophthalmology Clinics of North America  In: , Vol. 16, No. 4, 12.2003, p. 505-514.
  • "Introductory ophthalmic genetics." Ophthalmology Clinics of North America  In: , Vol. 16, No. 4, 12.2003, p. 501-503.
  • "In frame fibrillin-1 gene deletion in autosomal dominant Weill-Marchesani syndrome." Journal of Medical Genetics  In: , Vol. 40, No. 1, 01.01.2003, p. 34-36.
  • "Expression profile and genome location of cDNA clones from an infant human trabecular meshwork cell library." Investigative Ophthalmology and Visual Science  In: , Vol. 43, No. 12, 01.12.2002, p. 3698-3704.
  • "Genetic linkage of autosomal dominant primary open angle glaucoma to chromosome 3q in a greek pedigree." European Journal of Human Genetics  In: , Vol. 9, No. 6, 2001, p. 452-457.
  • "Identification and expression of a novel type I procollagen C-proteinase enhancer protein gene from the glaucoma candidate region on 3q21-q24." Genomics  In: , Vol. 66, No. 3, 15.06.2000, p. 264-273.
  • "GLC1F, a new primary open-angle glaucoma locus, maps to 7q35-q36." Archives of Ophthalmology  In: , Vol. 117, No. 2, 02.1999, p. 237-241.
  • "Malattia leventinese : Refinement of the genetic locus and phenotypic variability in autosomal dominant macular drusen." American Journal of Ophthalmology  In: , Vol. 126, No. 3, 09.1998, p. 417-424.
  • "Age-related macular degeneration : Clinical features in a large family and linkage to chromosome 1q." Archives of Ophthalmology  In: , Vol. 116, No. 8, 08.1998, p. 1082-1088.
  • "Insulin-like growth factor binding protein-5 expression by human trabecular meshwork." Investigative Ophthalmology and Visual Science  In: , Vol. 39, No. 1, 01.1998, p. 45-53.
  • "Prospects for genetic intervention in primary open-angle glaucoma." Drugs and Aging  In: , Vol. 13, No. 5, 1998, p. 333-340.
  • "Mapping a gene for adult-onset primary open-angle glaucoma to chromosome 3q." American Journal of Human Genetics  In: , Vol. 60, No. 2, 02.1997, p. 296-304.

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