Photo of Larisa G. Tereshchenko, M.D., Ph.D.

Larisa G. Tereshchenko M.D., Ph.D.

  • (503) 494-2374

    Portland Campus

    • Research Associate Professor of Medicine, Division of Cardiovascular Medicine School of Medicine
    • Physiology and Pharmacology School of Medicine
    • Biomedical Engineering School of Medicine
    • Medical Informatics and Clinical Epidemiology School of Medicine
    • Program in Molecular and Cellular Biosciences School of Medicine

Dr. Larisa G. Tereshchenko was born in Siberia (Omsk, USSR), in physicians’ family. Her father was obstetrician-gynecologist, the mother was an internist, uncle was an epidemiologist, and aunt was a pediatrician. Dr. Tereshchenko obtained MD degree with Honors from the Tyumen Medical School in 1986. She was the first-prize winner of the Internal Medicine Competition of the Russian Federation (individual competition), and USSR (team competition). Dr. Tereshchenko completed Cardiology & Cardiac Electrophysiology Fellowship in Omsk Medical School and received a Ph.D. degree from Novosibirsk Medical School in 1994. Dr. Tereshchenko conducted a prospective cohort study in the Far North, north of the Arctic Circle. In 1994, Dr. Tereshchenko joined the faculty of the Tyumen Medical School as an Assistant Professor of Medicine, and an attending cardiologist at the Tumen Regional Hospital. She taught clinical pharmacology, cardiology, and electrophysiology at the bedside, and was awarded an Institutional Award for the Excellence in Bedside Teaching and Clinical Service.
In 2004, Dr. Tereshchenko joined the faculty of the Washington University School of Medicine, where she initiated and conducted a prospective cohort study of ICD patients (ICD-EGMs study). After completion of cardiac electrophysiology fellowship at the Johns Hopkins Hospital, she joined the faculty of the Johns Hopkins School of Medicine, Cardiovascular Division. She established translational electrophysiology laboratory and developed several novel methods of ECG analyses, such as dynamic vectorcardiography, and a global measure of electrical heterogeneity sum absolute QRST integral. In 2013 Dr. Tereshchenko was awarded NIH R01 award “Novel ECG measures and risk of sudden cardiac death.” The objective of this study is development and validation of the novel ECG risk score of sudden cardiac death risk in the general population, and discovery of genetic factors associated with the novel mechanistic ECG phenotypes. In December 2013 Dr. Tereshchenko moved her laboratory to the Oregon Health and Science University in Portland, Oregon.

Areas of interest

  • Sudden Cardiac Death
  • Electrophysiology
  • Epidemiology
  • Randomized Clinical Trials
  • Biostatistics
  • Bioinformatics
  • Signal Processing

Education

  • M.D., Tyumen Medical School, Tyumen Russian Federation 1986
  • Ph.D., Omsk and Novosibirsk Medical School, Omsk and Novosibirsk Russian Federation 1994
  • Residency:

    • Residency, Internal Medicine (1986-1988); Tyumen Medical School.
  • Fellowship:

    • Fellowship, Cardiology & Cardiac Electrophysiology (1990-1994); Omsk & Novosibirsk Medical School
    • Cardiac Electrophysiology Research Fellowship (2007-2009); Johns Hopkins University.
  • Certifications:

    • ECFMG Certificate # 0-661-636-1 (2006)
    • Certificate of Cardiac Device Specialist-physician (CCDS) # 143862 (2008)

Honors and awards

  • Del Mar Junior Investigator Award (2013)

Memberships and associations

  • Fellow of the American Heart Association
  • Fellow of the American College of Cardiology
  • Fellow of the Heart Rhythm Society
  • Fellow of the International Society for Holter and Noninvasive Electrocardiology
  • Treasurer of the International Society for Computerized Eclectrocardiology
  • Member of the Cardiac Electrophysiology Society
  • Member of the American Medical Association
  • Member of the Heart Failure Society of America
  • Member of the Society of Clinical Trials
  • Member of the American Society of Echocardiography
  • Member of the International Society of Electrocardiology
  • Member of the Institute of Electrical and Electronics Engineers
  • Editor of the Heart Rhythm Journal
  • Editor of the Annals of Noninvasive Electrocardiology
  • Editor of the Journal of Electrocardiology

Publications

  • "Repolarization lability measured by spatial TT' angle"   2014
  • "Intracardiac QT variability in patients with structural heart disease on class III antiarrhythmic drugs" Journal of Electrocardiology November 2009
  • "Utilizing ECG-Based Heartbeat Classification for Hypertrophic Cardiomyopathy Identification" IEEE Transactions on Nanobioscience July 1 2015
  • "Repolarization lability measured on 10-second ECG by spatial TT′ angle" Journal of Electrocardiology  2014
  • "Transient Local Injury Current in Right Ventricular Electrogram After Implantable Cardioverter-Defibrillator Shock Predicts Heart Failure Progression" Journal of the American College of Cardiology August 25 2009
  • "Ventricular arrhythmia is predicted by sum absolute QRST integralbut not by QRS width" Journal of Electrocardiology November 2010
  • "VV' alternans triplets on near-field ICD intracardiac electrogram is associated with mortality" PACE - Pacing and Clinical Electrophysiology May 1 2015
  • "Controversy surrounding the best time for ICD implantation after myocardial infarction" Heart Rhythm June 2013
  • "A systematic review of the association between obstructive sleep apnea and ventricular arrhythmias" Journal of Clinical Sleep Medicine  2014
  • "Electromechanical relationship in hypertrophic cardiomyopathy" Journal of Cardiovascular Translational Research August 2013
  • "Number of P-wave fragmentations on P-SAECG correlates with infiltrated atrial fat" Annals of Noninvasive Electrocardiology  2014
  • "Electrocardiographic deep terminal negativity of the P wave in V1 and risk of mortality" Journal of Cardiovascular Electrophysiology November 1 2014
  • "Antiarrhythmic effect of reverse electrical remodeling associated with cardiac resynchronization therapy" PACE - Pacing and Clinical Electrophysiology March 2011
  • "Identifying hypertrophic cardiomyopathy patients by classifying individual heartbeats from 12-lead ECG signals"  December 29 2014
  • "Racial differences in sudden cardiac death" Journal of Electrocardiology November 1 2014
  • "Complex assessment of the temporal lability of repolarization" International Journal of Cardiology June 20 2013
  • "A new electrocardiogram marker to identify patients at low risk for ventricular tachyarrhythmias" Journal of Electrocardiology March 2011
  • "A wide QRS/T angle in bundle branch blocks is associated with increased risk for coronary heart disease and all-cause mortality in the Atherosclerosis Risk in Communities (ARIC) Study" Journal of Electrocardiology July 1 2015
  • "Beat-to-beat three-dimensional ECG variability predicts ventricular arrhythmia in ICD recipients" Heart Rhythm November 2010
  • "Autonomic tone in patients with supraventricular arrhythmia associated with mitral valve prolapse in young men" PACE - Pacing and Clinical Electrophysiology January 1 2003
  • "Infiltrated atrial fat characterizes underlying atrial fibrillation substrate in patients at risk as defined by the ARIC atrial fibrillation risk score" International Journal of Cardiology March 1 2014
  • "Arrhythmia risk stratification based on QT interval instability" Heart Rhythm June 2013
  • "A Patient Presents with Longstanding, Severe LV Dysfunction. Is There a Role for Additional Risk Stratification Before ICD?" Cardiac Electrophysiology Clinics June 2012
  • "Short-term variability of repolarization predicts ventricular tachycardia and sudden cardiac death in patients with structural heart disease" Heart Rhythm October 2011
  • "Development of analytical approach for an automated analysis of continuous long-term single lead ECG for diagnosis of paroxysmal atrioventricular block"   2014
  • "Diastolic dysfunction and autonomic abnormalities in patients with systolic heart failure" European Journal of Heart Failure April 2007
  • "QRS-T Angle" Annals of Noninvasive Electrocardiology November 1 2014
  • "Rationale and design for the Predictors of Arrhythmic and Cardiovascular Risk in End Stage Renal Disease (PACE) study" BMC Nephrology April 24 2015
  • "Intracardiac J-point elevation before the onset of polymorphic ventricular tachycardia and ventricular fibrillation in patients with an implantable cardioverter-defibrillator" Heart Rhythm October 2012
  • "Analysis of speed, curvature, planarity and frequency characteristics of heart vector movement to evaluate the electrophysiological substrate associated with ventricular tachycardia" Computers in Biology and Medicine October 1 2015

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