Photo of James T. Rosenbaum, M.D.

James T. Rosenbaum M.D.

  • (503) 494-5023
    • Professor of Ophthalmology School of Medicine
    • Professor of Medicine, Division of Arthritis and Rheumatic Diseases School of Medicine
    • Edward E. Rosenbaum Chair for the Study of Inflammatory Disease
    • Cell and Developmental Biology Graduate Program School of Medicine
    • Program in Molecular and Cellular Biosciences School of Medicine

Dr. Rosenbaum's clinical interests include uveitis and autoimmune disease. His research interests include uveitis, cytokines, leukocyte and endothelial interactions. He currently heads the Uveitis Clinic and is the director of inflammatory research at OHSU. Dr. Rosenbaum is the division chief of arthritis and rheumatic diseases. He is the Edward E. Rosenbaum professor of inflammatory diseases.

Dr. Rosenbaum received his medical degree in 1975 from Yale Medical School in New Haven, CT. He completed his medicine residency and rheumatology fellowship at Stanford Medical Center in Stanford, CA.

Education

  • M.D., Yale Medical School, New Haven Connecticut 1975
  • Residency:

    • Medicine-Stanford Medical Center, Stanford
  • Fellowship:

    • Rheumatology-Stanford Medical Center, Stanford

Memberships and associations

  • Internal medicine, 1978

Publications

  • "Ultraviolet irradiation induces the production of multiple cytokines by human corneal cells" Investigative Ophthalmology and Visual Science November 1997
  • "Uveitis associated with spondyloarthritis (I" Journal of Rheumatology  1990
  • "Gene expression profiling of whole blood" BMC Genomics January 5 2009
  • "Risk of hypotony in noninfectious uveitis" Ophthalmology November 2012
  • "Inflammatory eye disease"   2009
  • "Retisert Bausch & Lomb/control delivery systems" Current Opinion in Investigational Drugs November 2005
  • "Peripheral vascular leakage in uveitis" Ophthalmology June 1 2015
  • "Genetic studies in familial ankylosing spondylitis susceptibility" Arthritis and Rheumatology July 2004
  • "APCs in the anterior uveal tract do not migrate to draining lymph nodes" Journal of Immunology June 1 2004
  • "Nucleotide-binding oligomerization domain 2 and toll-like receptor 2 function independently in a murine model of arthritis triggered by intraarticular peptidoglycan" Arthritis and Rheumatology April 2010
  • "In reply [2]" JAMA Ophthalmology  2006
  • "Characterisation of uveitis in patients with psoriatic arthritis" Annals of the Rheumatic Diseases  2000
  • "The NOD2 defect in Blau syndrome does not result in excess interleukin-1 activity" Arthritis and Rheumatology February 2009
  • "Anterior uveitis" Seminars in Immunopathology  1999
  • "Prediction of cis-regulatory elements controlling genes differentially expressed by retinal and choroidal vascular endothelial cells" Journal of Ocular Biology, Diseases, and Informatics  2008
  • "Expression of growth factor mrna in rabbit pvr model systems" Current Eye Research  1992
  • "Prevention of EAE with monoclonal anti-I-A antibodies." Transactions of the American Neurological Association  1981
  • "NOD2, the gene responsible for familial granulomatous uveitis, in a mouse model of uveitis" Investigative Ophthalmology and Visual Science April 2008
  • "Letter" New England Journal of Medicine September 26 1974
  • "IL-1 and TNF receptor-deficient mice show decreased inflammation in an immune complex model of uveitis" Investigative Ophthalmology and Visual Science October 1999
  • "HLA-B27 and human β2-microglobulin affect the gut microbiota of transgenic rats" PLoS One August 20 2014
  • "CD40 gene polymorphisms confer risk of Behçet's disease but not of Vogt-Koyanagi-Harada syndrome in a Han Chinese population" Rheumatology (United Kingdom) January 2012
  • "The role of interleukin-6 in endotoxin induced uveitis in wild-type and IL-6 deficient mice" Investigative Ophthalmology and Visual Science February 15 1996
  • "The effects of topical S(+)-ibuprofen on interleukin-1 induced ocular inflammation in a rabbit model" Journal of Ocular Pharmacology and Therapeutics  1990
  • "Uveitis and arthritis" Seminars in Arthritis and Rheumatism  1982
  • "Autoantibodies and Sjogren's Syndrome in Multiple Sclerosis, a Reappraisal" PLoS One June 12 2013
  • "Epidemiology and Course of Disease in Childhood Uveitis" Ophthalmology August 2009
  • "β3-Adrenergic receptors mediate choroidal endothelial cell invasion, proliferation, and cell elongation" Experimental Eye Research January 2005
  • "Uveitis secondary to bacterial products" Ophthalmic Research April 2008
  • "The influence of uveitis on patients with immune-mediated inflammatory disease" Journal of Rheumatology November 2011

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