Photo of Howard K. Song, M.D., Ph.D.

Howard K. Song M.D., Ph.D.

Dr. Song is the chief of the Division of Cardiothoracic Surgery as of July 2012. He has been a member of the Division of Cardiothoracic Surgery at OHSU since 2004. He earned his undergraduate and medical degrees at Yale University and Stanford University and completed his clinical training at the University of Pennsylvania and Emory University. He serves as the surgery director of the Heart Failure and Transplant Program and the Thoracic Aorta Program at OHSU.

Dr. Song performs surgery for patients with all types of adult cardiovascular disease, including coronary artery disease, valvular heart disease, heart failure, and aortic aneurysms. His special areas of clinical interest include aortic and mitral valve repair, transplantation, ventricular assist devices, and aortic aneurysms.

Dr. Song is actively involved in both clinical and basic science research on cardiovascular disease. His research interests include biomedical and tissue engineering, genetically-triggered thoracic aortic aneurysms, and patient outcomes following cardiovascular surgery. He is actively involved in numerous cardiothoracic surgery societies and committees, is a reviewer for numerous cardiothoracic surgery journals, and has authored more than 80 journal articles.

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Areas of interest

  • Outcomes of patients undergoing adult cardiac surgery
  • Genetically triggered thoracic aortic aneurysms
  • Recombinant factor replacement following cardiopulmonary bypass to decrease postoperative bleeding
  • Bioengineering of prosthetic materials and blood pumps to improve biocompatibility

Education

  • B.S., Yale University, New Haven Connecticut 1989
  • M.D., Stanford University School of Medicine, Stanford California 1994
  • Ph.D., University of Pennsylvania Biomedical Graduate Studies, Philadelphia Pennsylvania 2001
  • Residency:

    • General Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, 2001
  • Fellowship:

    • Cardiothoracic Surgery, Emory University Affiliated Hospitals, Atlanta, GA, 2004
  • Certifications:

    • American Board of Thoracic Surgery, 2005

Memberships and associations

  • American Association of Thoracic Surgery
  • Society of Thoracic Surgeons

Publications

  • "Primary myxofibrosarcoma of the esophagus" Journal of Thoracic and Cardiovascular Surgery July 1 2002
  • "2012 update to the society of thoracic Surgeons guideline on use of antiplatelet drugs in patients having cardiac and noncardiac operations" Annals of Thoracic Surgery November 2012
  • "Evidence that anti-CD8 abrogates anti-CD4-mediated clonal anergy but allows allograft survival in mice1" Transplantation  1993
  • "GenTAC registry report" American Journal of Medical Genetics, Part A April 2013
  • "Impaired CD4 T cell activation due to reliance upon B cell-mediated costimulation in nonobese diabetic (NOD) mice" Journal of Immunology October 15 2000
  • "Surgical Treatment of Patients Enrolled in the National Registry of Genetically Triggered Thoracic Aortic Conditions" Annals of Thoracic Surgery September 2009
  • "I-A(g7)-mediated antigen presentation by B lymphocytes is critical in overcoming a checkpoint in T cell tolerance to islet β cells of nonobese diabetic mice" Journal of Immunology July 15 1999
  • "Mechanical circulatory support pathways that maximize post-heart transplant survival" Annals of Thoracic Surgery February 2013
  • "Engineering an endothelialized vascular graft" PLoS One December 19 2014
  • "Impaired activation of islet-reactive CD4 T cells in pancreatic lymph nodes of B cell-deficient nonobese diabetic mice" Journal of Immunology October 15 2001
  • "Elevated preoperative hemoglobin A1c level is predictive of adverse events after coronary artery bypass surgery" Journal of Thoracic and Cardiovascular Surgery September 2008
  • "Blood transfusion after coronary artery bypass graft surgery" JAMA - Journal of the American Medical Association January 12 2011
  • "Characterization of the alloimmune response to minor histocompatibility antigens by in vivo MLR" Transplantation Proceedings February 1999
  • "Specialized CC-chemokine secretion by Th1 cells in destructive autoimmune myocarditis" Journal of Autoimmunity December 2003
  • "Valve-sparing aortic root replacement in patients with Marfan syndrome enrolled in the National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions." The Journal of heart valve disease  2014
  • "Improved quality and cost-effectiveness of coronary artery bypass grafting in the United States from 1988 to 2005" Journal of Thoracic and Cardiovascular Surgery January 2009
  • "Becker's muscular dystrophy and orthotopic heart transplantation" Heart Surgery Forum  2006
  • "Gender Differences in Mortality After Mitral Valve Operation" Annals of Thoracic Surgery June 2008
  • "The National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC)" American Heart Journal October 2011
  • "Comparison of activation requirements and activation phenotype of allogeneic and xenogeneic rodent responses in vivo and in vitro" Transplantation August 15 2001
  • "Long-term implications of emergency versus elective proximal aortic surgery in patients with Marfan syndrome in the Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions Consortium Registry" Journal of Thoracic and Cardiovascular Surgery February 2012
  • "Changing presentation and management of neutropenic enterocolitis" JAMA Surgery September 1998
  • "Tracking alloreactive cell division in vivo" Transplantation July 27 1999
  • "Extracorporeal membrane oxygenation for ARDS in adults [8]" New England Journal of Medicine February 9 2012
  • "Cutting edge" Journal of Immunology March 1 1999
  • "Off pump coronary artery bypass surgery for significant left ventricular dysfunction" Heart April 2006
  • "Variation in use of blood transfusion in coronary artery bypass graft surgery" JAMA - Journal of the American Medical Association October 13 2010
  • "Contribution of the innate immune system to autoimmune diabetes" Cellular Immunology July 10 1999
  • "Favorable early outcomes for patients with extended indications for thoracic endografting" Heart Surgery Forum August 2009
  • "Safety and efficacy of prothrombin complex concentrates for the treatment of coagulopathy after cardiac surgery" Journal of Thoracic and Cardiovascular Surgery March 2014

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