Photo of Eneida R. Nemecek, M.D., M.S., M.B.A.

Eneida R. Nemecek M.D., M.S., M.B.A.

    • Professor of Medicine School of Medicine
    • Professor of Pediatrics School of Medicine
    • Medical Director for Clinical Research OHSU Knight Cancer Institute School of Medicine

Dr. Nemecek is involved in research to increase the understanding of pediatric cancers and other diseases that can be treated with bone marrow transplantation. She participates in research collaborations at the local level with the OHSU Knight Cancer Institute and at the national and international level with cooperative groups such as the Children's Oncology Group, Pediatric Blood and Marrow Transplant Consortium, Bone Marrow Transplant Clinical Trials Network and the Center for International Blood and Marrow Transplant Research. A variety of clinical trials are available for bone marrow transplant patients at Doernbecher. Areas of current research include:

Transplant regimens for pediatric cancers Transplant regimens for immunodeficiency syndromes, genetic diseases and inherited blood disorders Umbilical cord blood transplantation Nonmyeloablative and reduced-intensity regimens of transplantation Prevention and treatment of transplant complications Long-term outcomes of marrow transplantation

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Education

  • B.S., University of Puerto Rico, 0 1992
  • M.D., University of Puerto Rico School of Medicine, San Juan Puerto Rico 1996
  • M.S., University of Washington, Seattle Washington 2004
  • M.B.A., Oregon Health & Science University, Portland Oregon 2013
  • Residency:

    • Pediatrics, Rainbow Babies and Children’s Hospital, Case Western Reserve University, 1999
  • Fellowship:

    • Pediatric hematology/oncology, Fred Hutchinson Cancer Research Center, University of Washington, 2002
  • Certifications:

    • National Board of Medical Examiners, 1997

Memberships and associations

  • American Society of Pediatric Hematology/Oncology

Publications

  • "Hematopoietic stem cell transplantation for children with sickle cell disease" The Cochrane database of systematic reviews  2008
  • "Significant Improvement in Survival after Unrelated Donor Hematopoietic Cell Transplantation in the Recent Era" Biology of Blood and Marrow Transplantation January 1 2015
  • "Treosulfan, fludarabine, and 2-Gy total body irradiation followed by allogeneic hematopoietic cell transplantation in patients with myelodysplastic syndrome and acute myeloid leukemia" Biology of Blood and Marrow Transplantation  2014
  • "Use of radiolabeled antibodies in the treatment of childhood acute leukemia" Pediatric Transplantation  2003
  • "The genomic landscape of juvenile myelomonocytic leukemia" Nature Genetics November 1 2015
  • "Conditioning with Treosulfan and Fludarabine followed by Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies" Biology of Blood and Marrow Transplantation March 2011
  • "Comparison of pharmacokinetics and safety of voriconazole intravenous-to-oral switch in immunocompromised children and healthy adults" Antimicrobial Agents and Chemotherapy December 2011
  • "Outcome of allogeneic bone marrow transplantation for children with advanced acute myeloid leukemia" Bone Marrow Transplantation November 2004
  • "Evaluation of pentostatin in corticosteroid-refractory chronic graft-versus-host disease in children" Blood November 12 2009
  • "Comparison of pharmacokinetics and safety of voriconazole intravenous-to-oral switch in immunocompromised adolescents and healthy adults" Antimicrobial Agents and Chemotherapy December 2011
  • "Relapse after first allogeneic stem cell transplant for hematologic malignancies in children" Pediatric Transplantation November 2012
  • "Allogeneic human mesenchymal stem cell therapy (Remestemcel-L, Prochymal) as a rescue agent for severe refractory acute graft-versus-host disease in pediatric patients" Biology of Blood and Marrow Transplantation February 2014
  • "Antibody-based therapy of human leukemia" Current Opinion in Hematology  2002
  • "Child and parent perspectives of the chronic graft-versus-host disease (cGVHD) symptom experience" Supportive Care in Cancer  2014
  • "Extracorporeal adsorption therapy" Cancer Biotherapy and Radiopharmaceuticals April 1 2008
  • "Treatment of neuroblastoma in patients with neurocristopathy syndromes" Journal of Pediatric Hematology/Oncology February 2003
  • "A prospective study of G-CSF-primed bone marrow as a stem-cell source for allogeneic bone marrow transplantation in children" Blood December 15 2007
  • "Immune markers of disease severity and treatment response in pediatric acquired aplastic anemia" Pediatric Blood and Cancer March 2013
  • "Treosulfan-based conditioning and hematopoietic cell transplantation for nonmalignant diseases" Biology of Blood and Marrow Transplantation December 1 2014
  • "Biodistribution of yttrium-90-labeled anti-CD45 antibody in a nonhuman primate model" Clinical Cancer Research January 15 2005
  • "Transplantation Outcomes for Children with Hypodiploid Acute Lymphoblastic Leukemia" Biology of Blood and Marrow Transplantation July 1 2015
  • "Gastrointestinal complications"   2011
  • "Nonmyeloablative allogeneic hematopoietic stem cell transplant for the treatment of patients with hematologic malignancies using busulfan, fludarabine, and total body irradiation conditioning is effective in an elderly and infirm population" Biology of Blood and Marrow Transplantation January 1 2015
  • "Outcome of myeloablative conditioning and unrelated donor hematopoietic cell transplantation for childhood acute lymphoblastic leukemia in third remission" Biology of Blood and Marrow Transplantation December 2011
  • "Pretargeting CD45 enhances the selective delivery of radiation to hematolymphoid tissues in nonhuman primates" Blood  2009
  • "Hematopoietic stem cell transplantation for people with sickle cell disease." The Cochrane database of systematic reviews  2013
  • " 131I-anti-CD45 antibody plus busulfan and cyclophosphamide before allogeneic hematopoietic cell transplantation for treatment of acute myeloid leukemia in first remission" Blood March 1 2006
  • "Hematopoietic stem cell transplantation for children with sickle cell disease" The Cochrane database of systematic reviews  2009
  • "Exposure of early pediatric trainees to blood and marrow transplantation leads to higher recruitment to the field" Biology of Blood and Marrow Transplantation September 2013
  • "Challenges and opportunities for international cooperative studies in pediatric hematopoeitic cell transplantation" Biology of Blood and Marrow Transplantation  2013

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