Photo of David J. Rozansky, M.D., Ph.D.

David J. Rozansky M.D., Ph.D.

    • Professor of Pediatrics, Division of Nephrology School of Medicine
    • Associate Program Director, Pediatric Residency Program

Dr. Rozansky studies hormonal regulation of sodium transport in the kidney's distal nephron, an area of the kidney responsible for blood pressure control. He is especially interested in delineating the molecular mechanisms for how hormonal signals control specific sodium transporter. Characterizing these pathways will provide further targets for medication to control blood pressure. Recent publications include:J Clin Invest. 2009 Aug 17. pii: 38323. doi: 10.1172/JCI38323.

  • Residency:

    • Pediatrics, Northwestern University, Chicago IL 1997
  • Fellowship:

    • Pediatric nephrology, University of California, San Francisco, 2001
  • Certifications:

    • American Board of Pediatrics, pediatric nephrology subspecialty

Memberships and associations

  • American Board of Pediatrics

Publications

  • "Desensitization of epinephrine-initiated platelet aggregation does not alter binding to the α2-adrenergic receptor or receptor coupling to adenylate cyclase" Molecular Pharmacology  1986
  • "WNK kinases influence TRPV4 channel function and localization" American Journal of Physiology - Renal Fluid and Electrolyte Physiology June 2006
  • "Evolution of immunoglobulin deposition in C3-dominant membranoproliferative glomerulopathy" Pediatric Nephrology November 2013
  • "Molecular cloning, structure, and expression of dopamine-β-hydroxylase from bovine adrenal medulla" Journal of Neurochemistry  1990
  • "Hormone storage vesicle proteins. Transcriptional basis of the widespread neuroendocrine expression of chromogranin A, and evidence of its diverse biological actions, intracellular and extracellular" Annals of the New York Academy of Sciences  1994
  • "The role of aldosterone in renal sodium transport" Seminars in Nephrology March 2006
  • "Effects of Na+ on the muscarinic cholinergic receptor of rat ventricular myocytes" Journal of Cardiovascular Pharmacology  1985
  • "The impact of short stature on health-related quality of life in children with chronic kidney disease" Journal of Pediatrics September 2013
  • "Acute kidney injury associated with smoking synthetic cannabinoid" Clinical Toxicology  2014
  • "Structure and function of the chromogranin a gene" Journal of Biological Chemistry  1991
  • "Cell type-specific gene expression in the neuroendocrine system" Journal of Clinical Investigation July 1994
  • "Hypotonic induction of SGK1 and Na+ transport in A6 cells" American Journal of Physiology - Renal Fluid and Electrolyte Physiology  2002
  • "Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway" Journal of Clinical Investigation September 1 2009
  • "SGK integrates insulin and mineralocorticoid regulation of epithelial sodium transport" American Journal of Physiology - Renal Fluid and Electrolyte Physiology February 2001
  • "Assignment of the Chromogranin A (Chga) Locus to Homologous Regions on Mouse Chromosome 12 and Rat Chromosome 6" Genomics July 1993
  • "Catecholamine storage vesicle protein expression in genetic hypertension" Blood Pressure  1999
  • "Stimulus-transcription coupling in pheochromocytoma cells" Journal of Biological Chemistry  1996
  • "Glomerular basement membrane lipidosis in Alagille syndrome" Pediatric Nephrology June 2010
  • "Alemtuzumab induction with tacrolimus monotherapy in 25 pediatric renal transplant recipients" Pediatric Transplantation December 2013
  • "The effects of Na+ on the cholinergic muscarinic receptor of rat myocardium" Federation Proceedings  1984
  • "Glucocorticoid activation of chromogranin A gene expression" Journal of Clinical Investigation December 1994
  • "Characteristics of hypertension in premature infants with and without chronic lung disease" Pediatric Nephrology July 3 2017
  • "Phthalate-associated hypertension in premature infants" Pediatric Nephrology January 1 2019
  • "Use of Active Learning and Sequencing in a Weekly Continuing Medical Education/Graduate Medical Education Conference" Journal of Continuing Education in the Health Professions March 1 2019
  • "The changing spectrum of hypertension in premature infants" Journal of Perinatology January 1 2019

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