Pilot Projects

The MARC pilot program is designed to provide a flexible means for developing and exploring new and innovative research activities or directions, and unique opportunities that can evolve into independently funded research projects. The pilot program is also expected to attract investigators new to methamphetamine (MA) research.

Each year, the center funds approximately three pilot projects selected by the center's directors with input from our executive committee and advisory board. For information on the next round of pilot proposal submissions, please see our Pilot Project Program request for proposals.

Completed projects

Project 6D: Risky decision making in methamphetamine users: The role of opioid blockade
Todd Korthuis, M.D., Principal Investigator

Project 7F: Entacapone for methamphetamine abuse
Jonathan Fellers, M.D., Principal Investigator

Project 7G: Structural and biochemical dissection of the mechanism on inhibition by methamphetamine
Eric Gouaux, Ph.D., Principal Investigator

Project 7H: Methamphetamine and dopamine receptor effects on brain functional connectivity
Kim Neve, Ph.D., Damien Fair, Ph.D., Co-Principal Investigators

Project 8A: Acquisition and extinction of methamphetamine- and cocaine-induced memories
K. Matthew Lattal, Ph.D., Principal Investigator

Project 8B: Associations Between Methamphetamine Self-Administration and Impulsivity
Suzanne Mitchell, Ph.D., Principal Investigator
Gregory Mark, Ph.D., Co-investigator

Project 8C: Role of Histamine in the Long-Term Effects of Neonatal Methamphetamine Exposure on Cognition
Jacob Raber, Ph.D., Principal Investigator

Project 8D: TAAR1 as a Potential Anti-Methamphetamine Medications Target
David K. Grandy, Ph.D., Principal Investigator

Project 8E: Neuroimmune mediators of cognitive impairment in methamphetamine abuse
Marilyn Huckans, Ph.D., and Jennifer Loftis, Ph.D., co-Principal Investigators

Project 8F: Methamphetamine Use and Delay Discounting Among Individuals in Opioid Maintenance Treatment
Dennis McCarty, Ph.D., Principal Investigator

Project 8G: Role of D2L and D2S in mediating methamphetamine-induced behavior
Kim Neve, Ph.D., Principal Investigator

Project 8H: CRF system and methamphetamine sensitization
Andrey E. Ryabinin, Ph.D., Principal Investigator

Project 8I: Non-photic entrainment of the circadian clock: Role of methamphetamine
Charles Allen, Ph.D., Principal Investigator

Project 8J: Muscarinic Influence on Methamphetamine Discrimination
Matthew Ford, Ph.D., Principal Investigator

Project 8K: Mapping circadian modulation of methamphetamine response using functional imaging
Eilis Boudreau, M.D., Ph.D., Principal Investigator

Project 8L: Health Service Use and Outcomes in Veteran Methamphetamine Abusers 
Linda Ganzini, M.D., MPH, Principal Investigator

Project 6A: Muscarinic Influence on Methamphetamine Discrimination (and lntake)
Matthew Ford, Ph.D., Principal Investigator

Project 6B: Medial prefrontal cortex and extinction of psychostimulant self-administration
Matt Lattal, Ph.D., Principal Investigator

Project 6C: Stress Neuropeptide Pathways of Methamphetamine-Induced Behavioral Adaptation
Andrey Ryabinin, Ph.D., Principal Investigator

Project 6E: Neuroadaptive circadian rhythm changes with methamphetamine dependence
Melissa Weimer, D.O., M.C.R., Principal Investigator