Casey Innovations


We are proud to present Innovations, a publication describing some of the discoveries, innovations and advancements occurring in ophthalmology research and clinical care at OHSU Casey Eye Institute. At Casey, our programs have regional and national prominence. We are utilizing the power of world-class facilities to identify and treat the most complicated eye diseases, and we are leveraging the power of telemedicine to extend highly subspecialized care to patients across our region.

This publication highlights just a few of our programs that make OHSU Casey Eye Institute a leader in ophthalmic care. We are excited to be part of this transformative time in providing care.

Advancing surgery: Pioneering the first-ever CRISPR gene editing in vivo

Operating room team and surgeon perform first ever gene therapy procuedure using CRISPR technology

On Feb. 25, 2020, OHSU Casey Eye Institute led a unique moment in human history—the first gene editing procedure in a living person in all of medicine. As part of the BRILLIANCE clinical trial, OHSU Casey Eye Institute performed the procedure seeking to repair genes causing Leber congenital amaurosis type 10. 

Data-driven medicine: Using data analytics to solve real-world workflow challenges

An infographic representing reduced wait times due to informatics research.

Using data from electronic health record systems (EHRs), OHSU Casey Eye Institute informaticists created novel computer models designed to maximize clinic productivity without reducing patient satisfaction. Using new scheduling templates based on these models, average wait times in pediatric eye clinics reduced by 15 percent while clinic volumes increased by 15 percent. 

Inside the lab: Investigating spectroscopic OCT to measure capillary oximetry

New eye imaging technology captures blood oxygen saturation in retinal capillaries.

Ophthalmic imaging expert Yali Jia, Ph.D. and her team constructed a spectroscopic optical coherence tomography (OCT) instrument using visible-light band. They paired this instrument with a novel algorithm to extract the blood oxygen saturation in retinal capillaries in a preclinical model. Jia’s lab is the first to bring this technology to the capillary level.

Impacting the field

Elks Children's Eye Clinic building exterior photo by photographer Jeff Farrell

Casey Eye Institute is working to end preventable blindness in Oregon and beyond. Learn more about what we are doing in 2021 to impact the field of ophthalmology and eye health in our state.

Letter from Leadership

A child receives an eye exam from a pediatric ophthalmologist in the Elks Children's Eye Clinic.

Our vision is to redefine the standards of eye care for the people whom we serve in Oregon and beyond. We are honored to share some of the highlights of this year’s transformative work occurring at OHSU Casey Eye Institute.

Innovations 2021

The front cover of Innovations 2021 has a beautiful color enhanced eye image

View the full PDF version of Innovations 2021, including full articles and images.