Casey Innovations
Innovations
We are proud to present Innovations, a publication describing some of the discoveries, innovations and advancements occurring in ophthalmology research and clinical care at OHSU Casey Eye Institute. At Casey, our programs have regional and national prominence. We are utilizing the power of world-class facilities to identify and treat the most complicated eye diseases, and we are leveraging the power of telemedicine to extend highly subspecialized care to patients across our region.
This publication highlights just a few of our programs that make OHSU Casey Eye Institute a leader in ophthalmic care. We are excited to be part of this transformative time in providing care.
Advancing surgery: Pioneering the first-ever CRISPR gene editing in vivo

On Feb. 25, 2020, OHSU Casey Eye Institute led a unique moment in human history—the first gene editing procedure in a living person in all of medicine. As part of the BRILLIANCE clinical trial, OHSU Casey Eye Institute performed the procedure seeking to repair genes causing Leber congenital amaurosis type 10.
Data-driven medicine: Using data analytics to solve real-world workflow challenges

Using data from electronic health record systems (EHRs), OHSU Casey Eye Institute informaticists created novel computer models designed to maximize clinic productivity without reducing patient satisfaction. Using new scheduling templates based on these models, average wait times in pediatric eye clinics reduced by 15 percent while clinic volumes increased by 15 percent.
Inside the lab: Investigating spectroscopic OCT to measure capillary oximetry

Ophthalmic imaging expert Yali Jia, Ph.D. and her team constructed a spectroscopic optical coherence tomography (OCT) instrument using visible-light band. They paired this instrument with a novel algorithm to extract the blood oxygen saturation in retinal capillaries in a preclinical model. Jia’s lab is the first to bring this technology to the capillary level.
Impacting the field

Casey Eye Institute is working to end preventable blindness in Oregon and beyond. Learn more about what we are doing in 2021 to impact the field of ophthalmology and eye health in our state.