Keynotes and highlights
Laurie A. Boyer, Ph.D., Irvin and Helen Sizer Career Development Associate Professor of Biology at MIT
"Mending a broken heart"
Monday, May 2, 12 to 1 p.m., OHSU AuditoriumThis talk will focus on our recent efforts to dissect the transcriptional and epigenetic mechanisms that control cell fate decisions during mammalian heart development and how faulty regulation of these programs can lead to congenital heart defects. I will also discuss how we have begun to exploit the principles learned from our developmental studies to promote cardiac regeneration.Dr. Boyer earned her doctorate in biochemistry from the University of Massachusetts Medical School. Her graduate work focused on dissecting the biochemical mechanisms of chromatin remodeling enzymes. She then joined the Whitehead Institute in Cambridge, MA as a postdoctoral fellow where she pioneered the development of high-‐throughput platforms for genome wide analysis of transcription factors and chromatin regulators in stem cells, opening the field of stem cell genomics. Dr. Boyer was recognized as one of the world’s 50 top leaders in research by Scientific American for her innovative work in dissecting the core transcriptional regulatory circuitry in human ESCs. In 2007, Dr. Boyer joined the Biology Department at the Massachusetts Institute of Technology and is currently the Sizer Career Development Associate Professor of Biology and also holds a joint faculty position in the Biological Engineering Department. The Boyer lab investigates the gene regulatory mechanisms that coordinate lineage commitment during heart development and cardiac regeneration. Dr. Boyer has received numerous awards including a Pew Scholar in the Biomedical Sciences, the Smith Family Foundation for Excellence in Biomedical Research, and Massachusetts Life Sciences Center.
Dr. Boyer’s talk is sponsored by the School of Medicine Graduate Student Organization.
David J. Paterson, M.A., M.Sc., D.Phil., D.Sc., professor in the Department of Physiology, Anatomy, and Genetics, joint director of the Burdon Sanderson Cardiac Science Center, and vice dean of the Division of Medical Sciences at Oxford University
"Neurocardiology: Therapeutic opportunity?"
Professor Paterson, who was born and educated in New Zealand, is a graduate of the Universities of Otago, Western Australia, and Oxford. He is a leading cardiorespiratory physiologist and a world authority in cardiac-neural control. His work focuses on the relationship between cellular and molecular mechanisms in cardio-respiratory control during physiological stress, and how neural dysregulation contributes to cardiac pathology. Arrhythmia is often associated with autonomic imbalance, but it is not fully understood whether this is central to the onset of ventricular arrhythmia. The Paterson laboratory has identified a key role for the endogenous gaseous messenger nitric oxide as an intermediary in cardiac inter/intracellular signaling, and is working to understand the role played by the nitric oxide pathway in the regulation of cardiac sympatho-vagal neurotransmission and myocardial excitability in normal, diseased and exercise-trained hearts.
Reception to follow in the Richard Jones Hall atrium.
Monday, May 2, 1:30 to 4:30 p.m., OHSU Auditorium
The 2016 Jungers Symposium, "RNA granules: From synaptic plasticity to neurodegeneration," will take place on the first day of Research Week. This year's speakers include:
Kelsey Martin, M.D., Ph.D.
Professor of biological chemistry, psychiatry, and behavioral sciences, executive vice dean, and associate vice chancellor at the David Geffen School of Medicine at UCLA
"Spatial regulation of gene expression during synaptic plasticity"Martin was an English major as an undergraduate at Harvard, then served in the Peace Corps in the Democratic Republic of the Congo before returning to do graduate work at Yale. She was a postdoctoral fellow with Nobel laureate Eric Kandel at Columbia, where she began her work to understand the molecular basis of memories. Her work as a graduate student on ribonucleo-particle transport in influenza virus led her to the question of synapse-specific plasticity in the Kandel lab, then to a career examining neuronal signaling between synapses and gene expression in the nucleus, and on to RNA binding proteins. Martin has been on the faculty of UCLA since 1999 and now serves as the executive vice dean of the David Geffen School of Medicine.
Benjamin Wolozin, M.D., Ph.D.
Professor of pharmacology and neurology, and head of the laboratory of neurodegeneration at Boston University School of Medicine
"Stress granules and neurodegeneration: A molecular network underlying neurodegeneration"Wolozin was an undergraduate at Wesleyan before earning his medical and graduate degrees from Albert Einstein College of Medicine. After postdoctoral fellowships at Mt. Sinai and NIMH, he served as a faculty member at the Loyola University Medical Center before moving to Boston University in 2004. Wolozin is interested in how cellular stress response that regulates autophagy, protein translation, and mitochondrial function contributes to Parkinson's disease, Alzheimer's disease, and amyotrophic lateral sclerosis. In recent work he has examined the pathophysiology of stress granules (RNA-protein complexes) in Alzheimer's disease and tauopathies, which he will discuss in his 2016 Jungers Symposium talk.
J. Paul Taylor, M.D., Ph.D.
Chair of cell and molecular biology at St. Jude's Children's Research Hospital, and Howard Hughes Medical Institute investigator
"Perturbed RNA granule dynamics in ALS and related diseases"Taylor did his graduate training at Jefferson Medical College followed by a neurology residency at Penn and a neurogenetics fellowship at NINDS, where he worked with Kenneth Fischbeck and began his continuing interest in toxic, aggregation-prone proteins and neurological disease. He is currently chair of the Cell and Molecular Biology Department at St. Jude Children's Research Hospital in Memphis, and an HHMI investigator. His work focuses on RNA-protein granules whose functional impairment has been implicated in multiple neurodegenerative diseases including ALS and frontotemporal dementia. In his work, he uses Drosophila to model disease, and is interested in development of small molecule therapeutics. Taylor has examined how disease-causing mutations affect RNA granule formation and the development of fibrillary inclusions of RNA-binding proteins.
Tuesday, May 3, 5:15 to 7 p.m., Richard Jones Hall Atrium
The Postdoc and Graduate Student Alumni Networking Night is an annual career networking event held in conjunction with OHSU's Research Week and sponsored by the OHSU School of Medicine Alumni Association. The event usually draws over 100 postdoctoral and graduate level scientist that are exploring different career options by learning about various career paths that people have taken. The event is very informal and is set up so that there are 20-25 small group conversations happening at once. Each career expert will talk about their day-to-day job activities and the path that they took to get in their position. Think of it as small group informational interviews! By learning about a wide variety of careers and unique career paths, postdocs and graduate students will have a better sense of the steps they need to take to achieve their career goals.Registration and open networking begins at 5:15pm and the event will kick off at 5:30 with a hosted buffet dinner. Participants are encouraged to grab some food then locate the seating area for a professional of interest. The OHSU Alumni Association will provide some brief opening remarks, and then the fun begins: each round will consist of 15 minutes, during which time our professionals will speak briefly about their career path, followed by open questions and answers from the participants. After 15 minutes, we will ring a bell signifying the end of the round, and you will have a few minutes to locate your next professional of interest. We will run up to five rounds of speed dating, giving you the chance to talk to five diverse and amazing professionals from a variety of career paths!
Career Experts:Darcie Babcock, M.S., Lab manager for Dr. Joe Gray's lab at OHSU.
Darcie Babcock received a B.Sc. in Biology from the University of Puget Sound in Biology and an M.Sc. from Portland State University in Biology with an emphasis on Molecular Genetics. She has worked at OHSU for 25 years in a variety of research positions and currently the lab manager for Joe Gray.
LinkedIn Profile: https://www.linkedin.com/in/darcie-babcock-13b0bb54
Sarah Byers, Ph.D., Assistant
Research Integrity Officer – Institutional Biosafety Committee, Research
Integrity Office (ORIO), OHSU
Ph.D., Assistant Professor, University of Portland
Previously, Nicola Carter was a Research Assistant Professor in the Ullman Lab at OHSU.
Ph.D., Assistant Professor of Chemistry, Reed College
Kelly Chacon studies how metal ions are trafficked in the cell by using a mixture of biochemistry and spectroscopy. Her lab is particularly interested in catching the physical act of metal ion transfer from one metalloprotein to another, as well as characterizing newly discovered metalloproteins. This work heavily relies upon bi-yearly lab trips to a number of synchrotron lightsources. At Reed, she will begin teaching Introductory Chemistry and Metabolic Biochemistry (with an emphasis on metals, of course). She is heavily involved in the bioinorganic chemistry community —and the 2016 chair of the Gordon Research Seminar in Bioinorganic Chemistry, as well as an elected member of the Stanford Synchrotron Radiation Lightsource Users Executive Committee. She invites anyone who wants to know more about her work to stop by for a cup of tea —it is her true pleasure to translate her science for the public and potential students.
LinkedIn Profile: https://www.linkedin.com/in/kelly-chac%C3%B3n-b471a645
Ph.D. Translational Strategist, Due North Innovation, Portland, OR
Sudeshna was a Postdoctoral Researcher at Oregon Health &Science University, and who received an M.D. at Doctor of Philosophy, Molecular &Cellular Biology, University of Maryland at College Park. Currently, as a Translational Strategist for Due North Innovation, Sudeshna helps with the process of commercialization by serving as a link between research and Industry. Through the evaluation and assessment of new technology, as well as the documentation, reporting and tracking of new discoveries, Sudeshna's efforts ensure that products developed at Due North remain at the forefront of scientific understanding. Creating product test protocols, as well as lab development, resource allocation and materials management planning are also core to Dr. Dutta's sketch to launch contribution.
LinkedIn Profile: https://www.linkedin.com/in/sudeshnadutta
Clinical Research Manager, Prostate Cancer Research Group, OHSU Knight Cancer
Kristi is a Clinical Research Manager at the OHSU Knight Cancer Institute.
Marissa Frieder, Ph.D., Grants
Manager, Institute on Development and Disability, Center for Women's Health,
Marisa received her PhD in Microbiology &Immunology from The George Washington University School of Medicine and Health Sciences and did her Postdoctoral Fellowship in Infectious Disease at OHSU. She went into research administration straight from the lab and hasn't looked back! In her current position, Marisa manages a team of 8 grant administrators to ensure good service and professional development. She also ensures compliance with university, funder and federal requirements in grant proposals, grant administration and subaward monitoring. Marisa is extremely passionate about informing graduate students and postdocs about alternative careers and has amazing personal insight into the career journey after the lab!
LinkedIn Profile: https://www.linkedin.com/in/marisa-frieder-8575ba9
Ph.D., Events, Education, &Marketing Coordinator, Oregon Biosciences
Ashley received her Ph.D. in chemical engineering from U.C. Berkley. She is currently the Events, Education, &Marketing Coordinator for Oregon Bioscience Association. The Oregon Bioscience Association supports the regional bioscience community through networking, educational programs, enterprise support, advocacy, and the enhancement of research collaboration. As the collective voice for the bioscience community on behalf of Oregon's bioscience companies, Oregon Bio is responsible for communicating the industry's impact, issues and challenges to the public sector, educators and the general public.
LinkedIn Profile: https://www.linkedin.com/in/alfritz
M.B.A., Operations Manager, TTBD, OHSU
Nicole Garrison has worked in the OHSU office of Technology Transfer and Business Development since 2007. She is the Operations Manager for the department, in which she is involved with compliance, database administration, and HR coordination. She also runs TTBD's internship program, which allows interns the opportunity to learn and get hands on experience in technology transfer, business development, and patent law. Nicole is a graduate of Oregon Health &Science University's and Portland State University's joint Healthcare MBA program. She also holds a Bachelor of Arts degree in Psychology from Lewis &Clark College, where she graduated magna cum laude, Phi Beta Kappa, and with departmental honors.
LinkedIn Profile: https://www.linkedin.com/in/nicole-garrison-870a8a31
DrPH, MHA, Senior Director, Neuroscience and Spine, Oregon Health and Science
Gina Hawley is the Senior Director of Neuroscience and Spine at OHSU where she oversees operations, finances, and strategic planning for the hospital service line. Prior to coming to OHSU, Gina was the Assistant Administrator for Neurology and Neurosurgery at Johns Hopkins Hospital managing hospital operations and performance improvement. Gina's previous experiences include being a Sr. Project Analyst for the Department of Medicine at Johns Hopkins, a Nursing Assistant for High Risk OB/Labor &Delivery at Nebraska Methodist Hospital, and a volunteer Speaker's Bureau Coordinator for the Nebraska AIDS Project. Gina has her Bachelors, Masters, and Doctorate in Public Health in Health Management
LinkedIn Profile: www.linkedin.com/in/ginahawley
Ph.D., Professor and Vice-Chair for
Research, Dept. Neurological Surgery and Associate Dean for Basic Science in
the School of Medicine
Mary Heinricher education background is B.A. University of Missouri St. Louis, 1977;Ph.D. Northwestern University, 1983;Post-doc University of California San Francisco 1983 –85. She is a basic scientist working in a clinical department (Neurological Surgery), where she studied how the brain controls pain. She also works as Associate Dean for Basic Science in the School of Medicine, where she supports the scientists across the School of Medicine, whether in basic science and clinical departments.
Ph.D., Data scientist-urban airship
Todd Johnson received his Ph.D. from the University of California, Irvine in Artificial Intelligence, Machine Learning, Computation Biology. He is currently a Data Scientist at Urban Airship.
LinkedIn Profile: https://www.linkedin.com/in/toddjohnson3
Ph.D., Data scientist-urban airship
Lisa Orr received a B.S. in Biology at UCSC, Ph.D. in Psychology at the University of St. Andrews where she studied gestural communication of bonobos. Her current position analyzes transactional mobile phone data, builds predictive models, reports findings to various teams from product and engineering to sales and marketing.
LinkedIn Profile: www.linkedin.com/in/lisaorr
Ph.D., Technical Consultant/Patent Agent
Jennifer Johnson received her Ph.D. in Molecular and Medical Genetics from Oregon Health &Science University. She is a Technical Consultant at Alleman Hall McCoy Russell &Tuttle LLP and provides technical consultation over a wide range of scientific fields. Her research experience includes DNA repair, mutagenesis, cancer biology, and cytotoxicity within a mammalian cell culture model. She has also an author of peer-reviewed publications in scientific journals.
Michaelis Wood Lowrance, PHR, Human Resources Manager for the Knight Cancer Institute,
Michaelis has over seven years of progressively responsible human resources management experience and an additional five years of experience in management, customer service, sales and marketing. She's involved in new talent recruitment and has valuable insight to future positions needed for the Knight Cancer expansion.
LinkedIn Profile: https://www.linkedin.com/in/michaeliswoodlowrance
J.D., A.M., The Patent Option
As an attorney who has practiced patent law for over 15 years, Janina Malone provides drafting and prosecution services for law firms, universities and corporations. She has drafted and prosecuted patents in the areas of pharmaceuticals, novel chemical compounds, immunology, immunotherapy, inhibitors of cellular differentiation, cellular assays, transgenics, siRNA, neurology, lipid sciences, treatments for pain, treatments for neuropathy, and metabolic disorders, as well as biomimetics, biosensors, nanotechnology, bioinformatics, and medical devices. While her practice primarily focuses on biotechnology, she has also drafted and prosecuted applications for mechanical devices, optics, engines, emission controls, virtual reality, and media systems. She was previously a patent associate with a national, 500+ attorney law firm. She decided to venture out on her own in 2004 and had enjoyed this business model so much she has never looked back.
LinkedIn Profile: https://www.linkedin.com/in/janinamalone
Aditi Martin, Ph.D.,
CLP, Program Director, OCTRI Pilot Awards and Biomedical Innovation Program
In her current role, Aditi Martin manages a variety of funding programs that are offered by the Oregon Clinical and Translational Research Institute (OCTRI), including the Biomedical Innovation Program. Aditi aims to develop a dynamic interface between OCTRI and the research community. Previously, she served in the Office of Technology Ventures at Johns Hopkins University, facilitating business development and the translation of biomedical advances. She has in-depth experience with evaluating, marketing, and managing intellectual property and a diverse portfolio of technologies;developing key collaborative relationships and negotiating commercialization agreements. Aditi has a Ph.D. in Pharmacology and Toxicology and is a Certified Licensing Professional
LinkedIn Profile: https://www.linkedin.com/in/aditimartin
Ph.D., Director of Collaborative Research for Extreme-Scale Technologies, Intel
Anne Matsuura is the Director of Collaborative Research for Extreme-Scale Technologies at Intel Corporation, where she leads both a biological/chemical molecule sensor technology team and a quantum computing applications/algorithms research group. She left her position as the Chief Scientist of the Optical Society (OSA) to come to Intel in 2014. Previously, Dr. Matsuura worked in Belgium as the Chief Executive of the European Theoretical Spectroscopy Facility (ETSF), an organization of 250 scientists throughout Europe providing scientific collaborations, modeling and simulation, and open-source software to the public and private sectors. Prior to the ETSF, she held positions as a senior scientist at a strategic investment firm (In-Q-Tel), as a program manager for atomic physics at the U.S. Air Force Office of Scientific Research, and as a special assistant to the U.S. Deputy Under Secretary of Defense for Laboratories and Basic Science. She has also been a researcher at Lund University in Sweden, Stanford University, the University of Tokyo, and was an adjunct professor in the physics department at Boston University. Dr. Matsuura received a Fulbright Scholarship to Nagoya University (Japan), has been a recipient of the Office of the Secretary of Defense Award for Excellence, and was an American Association for the Advancement of Science (AAAS) Science and Technology Fellow. She received her Ph.D. in physics from Stanford University
LinkedIn Profile: https://www.linkedin.com/in/annematsuura
Ph.D., Associate Director of Strategic Partnerships, Brenden-Colson Center for
Pancreatic Care, OHSU
Previously, Bree Mitchel was in Stanford University, Life Technologies, Promega Biosystems, Intel, Fred Hutchinson Cancer Research Center. Bree has worn many hats in her career –research scientist, manager, marketer, strategist, and project manager. As a result, she has a unique ability to manage multi-disciplinary projects and to navigate complex challenges. Over the past 10 years, she has focused her professional development on: Strategic Planning - expertise in creating project and organizational roadmaps; Program and Product Launch - passionate about translating vision, concepts and ideas into feasible, implementable programs and products; Building Collaboration - proficiency in developing, implementing and managing cross-departmental and cross-organizational programs;and Technology Development: Experience in identifying and advocating for promising new technologies.
LinkedIn Profile: https://www.linkedin.com/in/bree-mitchell-427ab92
Ph.D., Assistant professor, University of Oregon
Annie Powell is a tenure-track Assistant Professor of Biology in the Institute of Molecular Biology at the University of Oregon. She grew up in Montana, graduated with a Bachelor of Arts from Concordia University in Portland, Oregon. In 2010, she earned her Ph.D. in Dr. Melissa Wong's lab at OHSU. From there, she moved to Dr. Robert Coffey's lab at Vanderbilt University Medical Center, where she continued to investigate the stem cells of the small intestine and colon in both mice and humans. During her postdoc she published two first-author papers, inducing one in Cell, and received two nationally competitive Career Development Awards: the American Gastroenterological Association's Research Scholar Award in 2014 and a K01 from the NIH: National Institute for Digestive and Kidney Diseases in 2015. Annie started her own lab in April 2015, where she has five trainees (undergrad up to postdoc) that studies the role of stem cells in tissue injury and repair, as well as host-microbe interactions.
B.A., US Technical Recruiter- ProActive Talent Solutions at Intel Corporation
Sarah Sunderland received her B.A. in Communication from Oregon State University. She has been a talent recruiter for various corporations for the past six years and now specialized as a technical recruiter for new talent at Intel.
LinkedIn Profile: https://www.linkedin.com/in/sarah-sunderland-a682ab21
Ph.D., Scientific Director for Dr. Brian Druker's Lab at OHSU
After receiving her B.Sc. in Genetics from the University of London, Ontario, Cristina Tognon obtained a Ph.D. in Medical Genetics from the University of British Columbia and went on to do post-doctoral training at the Child and Family Research Institute and the BC Cancer Agency in Vancouver, Canada. She moved to Portland four years ago to become the Scientific Director Dr. Brian Druker's lab. In her role, she helps to oversee the scientific direction of the lab and its overall management. Her role is to oversee the scientific direction of the research and to aid with the overall management of the laboratory and help lead a large program call Beat AML, supporting clinical trial development, write grants and manuscripts, supervise technicians and students, and implement infrastructural support to maintain a high functioning lab.
LinkedIn Profile: https://www.linkedin.com/in/cristina-tognon-1b234a10
Norah G. Verbout,
Ph.D., Project Manager and Senior Scientist at Aronora
Norah Verbout is a Senior Scientist &Project Manager at Aronora, Inc., a translational biotech company engaged in early-stage commercial development of biological therapeutics. Aronora has received over 16M in undiluted funding and is beginning the Investigational New Drug (IND) process for two drug candidates. Since 2010, she has been directly involved in the preclinical development of one of these lead drug candidates and a co-Principal Investigator on an NIH Small Business Innovation Research (SBIR) Fast-track grant for this molecule. For these projects, she has contributed to efficacy studies, managed manufacturing activities, overseen protein characterization, and preclinical safety testing. She received a Ph.D. in Physiology &Pharmacology from OHSU.
LinkedIn Profile : https://www.linkedin.com/in/norahverbout
Caldwell, M.S., President at Catalysis LLC
Chris has an extensive background in strategic planning, group facilitation, program development, and corporate social responsibility. She serves organizations ranging from corporations, science and research institutions, to non-profit service organizations. She served as a peer reviewer for National Science Foundation (NSF) and participated in multi-institutional grants with NASA, NSF and the National Institutes of Health (NIH) Science Education Partnership Awards. She works throughout Oregon and the U.S., including Puerto Rico. Internationally she serves clients in Brazil, China, Germany, Ireland, Japan, Singapore, South Korea, and the UK. Her broad experience allows her to understand a breadth of organizational visions and styles.
Tuesday, May 3, 12 to 1:30 p.m., OHSU AuditoriumYou are invited to watch seasoned reviewers discuss NIH proposals as if you were there! The Mock NIH Study Section, led by Charles Rafferty, Ph.D., will review an NIH K career development and R01 application with a panel of faculty acting as reviewers. This event will demonstrate how grants are evaluated and discussed through the NIH peer review process - and provide insight into improving your own grantsmanship. In addition, you get to participate! The audience will be asked to score the applications on a clicker, with results displaying in real time.
In preparation for the event, please read the two grant applications – the K23 and the R01 – and browse through the NIH review materials, including critique templates, review guidance and NIH scoring table. If you’re short on time, read the R01’s Specific Aims and the K23’sCareer Development Plan. As you will see, these are actual NIH proposals that have been redacted to protect the innocent. All materials can be found here. You need your OHSU credentials to log in.Charles N. Rafferty, Ph.D., is a health research and grants policy consultant with extensive experience in managing research programs and planning and conducting peer review in environmental, and occupational health and clinical research in musculoskeletal, skin, and rheumatic diseases. Specific services include assisting and collaborating in the writing of research grant applications and contract proposals from research institutions and universities, training of pre-and postdoctoral staff, organizing and managing peer review for sponsoring institutions, and strategic planning, development and evaluation of health research programs. From 2009-2014, Dr. Rafferty was the Chief of the Scientific Review Branch at the National Institute of Arthritis, Musculoskeletal, and Skin Diseases (NIAMS), the National Institutes of Health (NIH). In this position, he oversaw all grant and contract peer review activities carried out by NIAMS. Dr. Rafferty received his Ph.D. in Biophysics from The Ohio State University and held postdoctoral positions at the Kernforschungsanlage Jülich in Germany, at Cornell University, and at the National Eye Institute, NIH. He was also a research chemist at the Walter Reed Army Institute of Research, where he developed a cellular biophysics research program to provide a basis for standards-setting for microwave exposure. From 1987 to 2000, Dr. Rafferty was a senior manager with the Electric Power Research Institute, Palo Alto, California, where he conducted and managed research related to the health risk assessment of power line electromagnetic fields. Dr. Rafferty returned to government service as a Scientific Review Officer and Referral Officer with the Center for Scientific Review, NIH. In 2005, he was appointed as Assistant Director for Review and Policy, National Institute for Occupational Safety and Health, Centers for Disease Control, where he organized and managed a new extramural grant peer review group. Dr. Rafferty has published extensively in environmental risk assessment, photobiology, visual receptor mechanisms, and microwave health effects. He is a past Gordon Conference Chair and has received numerous achievement awards.
The Mock Study Section is sponsored by Oregon Clinical & Translational Research Institute.