OHSU

Brett C. Sheppard, M.D.

Head Shot of Brett Sheppard

Professor

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Office: 
503 494-4373

Background

Dr. Sheppard has a focused clinical interest in surgical diseases of the pancreas with a special interest in the care of patients with pancreatic cancer. In addition he maintains expertise in the surgical care of disease of the foregut (stomach and esophagus) and endocrine diseases of the pancreas and the adrenal gland. Whenever possible, Dr. Sheppard utilizes his expertise in MIS for surgical care. Dr. Sheppard is deeply committed to patient safety and the enhancement of the quality of surgical care and is a member of quality care working groups both at OHSU and for the state of Oregon. His research interests are focused on improving outcomes for pancreatic cancer by earlier diagnosis and improved therapy, the enhancement of outcomes in gastro-intestinal (GI) and GI endocrine surgery and the optimization of MIS techniques. He is a member of the OHSU Knight Cancer Institute, the surgical principal investigator for OHSU of the American College of Surgeons Oncology Group and a member of the Southwest Oncology Group. This provides for excellent state of the art interdisciplinary cancer care through clinical trials. In addition he is a member of national and international scientific societies dedicated to progress in patient care for open and MIS GI surgery.


Selected Publications

"N terminus of ASPP2 binds to Ras and enhances Ras/Raf/MEK/ERK activation to promote oncogene-induced senescence," Proceedings of the National Academy of Sciences of the United States of America (Vol: 110, Issue: 1, Page 312-317) - 2013

"Human pancreatic cancer fusion 2 (HPC2) 1-B3: a novel monoclonal antibody to screen for pancreatic ductal dysplasia.," Cancer cytopathology (Vol: 121, Issue: 1, Page 37-46) - 2013

"Coagulopathy after a liver resection: Is it over diagnosed and over treated?," HPB (Vol: , Issue: , Page ) - 2013

"The novel monoclonal antibody HPC2 and N-cadherin distinguish pancreatic ductal adenocarcinoma from cholangiocarcinoma," Human Pathology (Vol: 43, Issue: 10, Page 1583-1589) - 2012

"Symptomatic venous thromboembolism after femoral vein harvest," Journal of Vascular Surgery (Vol: 56, Issue: 3, Page 696-702) - 2012

 

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503 494-4373

Memberships & Associations

American College of Surgeons
American Pancreatic Association
American HepatoPancreatobiliary Association
Society for Surgical Oncology
Society of American Gastrointestinal and Endoscopic Surgeons