Charlie Robert Phillips

Email:: click here

Background

In 2004, Dr. Phillips founded the Center for Intensive Care Research (CICR) at OHSU. The purpose of the CICR is to develop an infrastructure and assemble expertise to facilitate critical care clinical research at OHSU. In addition, Dr. Phillips helped facilitate OHSU’s inclusion into the ARDSNet group as a satellite center to UCSF. He has initiated several large clinical studies at OHSU examining the pathophysiology of ARDS, and SIRS/Sepsis

Dr. Phillips has also helped to form an ongoing collaborative group of investigators to include bioengineers, system scientists, pediatric and adult intensivists to develop a sophisticated closed loop controller of perfusion in septic patients.

Research Interests:

Cardiovascular physiology

Hemodynamic monitoring in sepsis and hemorrhagic shock

Closed loop control in shock,

Acute lung injury/ARDS,

Pulmonary neutrophil sequestration

Selected Publications

"Lung water-the pool of evidence deepens," Critical Care Medicine (Vol: 41, Issue: 2, Page 673-674) - 2013

"Extravascular lung water predicts progression to acute lung injury in patients with increased risk*," Critical Care Medicine (Vol: 40, Issue: 3, Page 847-854) - 2012

"The camel curve: The icing on the transpulmonary thermodilution cake," Critical Care Medicine (Vol: 39, Issue: 3, Page 611-612) - 2011

"Transpulmonary determination of extravascular lung water: What you see is what you get and it's useful," Anesthesiology (Vol: 112, Issue: 6, Page 1540-1541) - 2010

"Techniques for Determining Cardiac Output in the Intensive Care Unit," Critical Care Clinics (Vol: 26, Issue: 2, Page 355-364) - 2010

"Measuring extravascular lung water (and derived parameters) in patients with acute respiratory distress syndrome: What's right, what's wrong, and what's ahead?," Critical Care Medicine (Vol: 37, Issue: 6, Page 2118-2119) - 2009

"Resuscitation of haemorrhagic shock with normal saline vs. lactated Ringer's: Effects on oxygenation, extravascular lung water and haemodynamics," Critical Care (Vol: 13, Issue: 2, Page ) - 2009

"Pulmonary artery catheters in acute heart failure: end of an era?," Critical care (London, England) (Vol: 13, Issue: 6, Page 1003-) - 2009

"Predicted body weight-indexed extravascular lung water is elevated in acute respiratory distress syndrome," Critical Care Medicine (Vol: 37, Issue: 1, Page 377-378) - 2009

"Randomized clinical trial of activated protein C for the treatment of acute lung injury," American Journal of Respiratory and Critical Care Medicine (Vol: 178, Issue: 6, Page 618-623) - 2008

"Extravascular lung water as a predictor of mortality in acute respiratory distress syndrome," Critical Care Medicine (Vol: 36, Issue: 7, Page 2221-2222) - 2008

"Complexity analysis of arterial pressure during periods of abrupt hemodynamic changes," IEEE Transactions on Biomedical Engineering (Vol: 55, Issue: 2, Page 797-801) - 2008

"Extravascular lung water in sepsis-associated acute respiratory distress syndrome: Indexing with predicted body weight improves correlation with severity of illness and survival," Critical Care Medicine (Vol: 36, Issue: 1, Page 69-73) - 2008

"Trends in heart failure mortality in England and Wales since 1950," European Journal of Internal Medicine (Vol: 18, Issue: 8, Page 576-580) - 2007

"Design and implementation of a portable physiologic data acquisition system," Pediatric Critical Care Medicine (Vol: 8, Issue: 6, Page 563-569) - 2007

"A novel algorithm to estimate the pulse pressure variation index Î”PP," IEEE Transactions on Biomedical Engineering (Vol: 51, Issue: 12, Page 2198-2203) - 2004

"Direct coextensive plethysmography for non-invasive measurement of systemic pressures and volumes," Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (Vol: 26 III, Issue: , Page 2318-2321) - 2004

"Systolic blood pressure variability as a risk factor for stroke and cardiovascular mortality in the elderly hypertensive population," Journal of Hypertension (Vol: 21, Issue: 12, Page 2251-2257) - 2003

"Pulse Pressure Variation Estimation Based on Rank-Order Filters," Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (Vol: 3, Issue: , Page 2435-2438) - 2003

"Decreased exhaled nitric oxide in subjects with HIV infection," Thorax (Vol: 52, Issue: 2, Page 185-186) - 1997

"Exhaled nitric oxide during exercise: Site of release and modulation by ventilation and blood flow," Journal of Applied Physiology (Vol: 80, Issue: 6, Page 1865-1871) - 1996