Owen J.T. McCarty, Ph.D.
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Background
Dr. McCarty received his Ph.D in Chemical & Biomolecular Engineering from Johns Hopkins University with dissertation work focused on the role of platelets in cancer metastasis and thrombosis. As a Wellcome Trust Postdoctoral Fellow, he continued his research in the area of thrombosis, examining the signaling pathways governing platelet cytoskeleton reorganization, at the Department of Pharmacology, Oxford University and Centre for Cardiovascular Sciences, University of Birmingham, UK.
Summary of Current Research
Research Interests Dr. McCarty's research is focused on understanding the interplay between cell biology and fluid mechanics in the cardiovascular system. In particular, his research into the balance between hydrodynamic shear forces and chemical adhesive interactions has great relevance to underlying processes of cancer, cardiovascular disease, and inflammation. Research Projects Thrombosis and Hemostasis Research Groups Cardiovascular and Blood Research Vascular Biology and Vascular Tissue Engineering
Selected Publications
"Exogenous modification of platelet membranes with the omega-3 fatty acids EPA and DHA reduces platelet procoagulant activity and thrombus formation,"
"Molecular imaging of inflammation and platelet adhesion in advanced atherosclerosis effects of antioxidant therapy with NADPH oxidase inhibition.,"
"Hyaluronan oligosaccharides perturb lymphocyte slow rolling on brain vascular endothelial cells: Implications for inflammatory demyelinating disease,"
"Rho GTPases in platelet function,"
"Development of a label-free imaging technique for the quantification of thrombus formation,"
