Shiuh-Wen Luoh, M.D., Ph.D.
- Email:
- click here
Background
Dr. Luoh’s research focuses on developing new biomarkers and targets for novel therapy in breast cancer. His laboratory examines the functional involvement of several genes from the HER-2 region on the human chromosome 17 in breast cancer. His laboratory has recently shown that the GRB7 gene, which encodes a signal transduction molecule from the HER-2 region, is an independent adverse prognostic factor in breast cancer. His ongoing research aims to understand why some patients fail to respond to currently available HER-2 targeted therapy and to develop a new HER-2 testing strategy with improved accuracy. In addition, working with a well-annotated breast tumor repository with long-term clinical follow-up at the OHSU Knight Cancer Institute, Dr. Luoh’s most recent endeavors are directed at understanding the mechanism of late breast cancer relapse (more than five years after initial diagnosis and successful treatment). This is an important and as yet, a little understood area. A breakthrough in this area is vital to our achievement of zero recurrence for women diagnosed with breast cancer.
Selected Publications
"Comparison of tai chi vs. strength training for fall prevention among female cancer survivors: Study protocol for the GET FIT trial,"
"Impact + resistance training improves bone health and body composition in prematurely menopausal breast cancer survivors: a randomized controlled trial,"
"Breast cancer medications and vision: Effects of treatments for early-stage disease,"
"GRB7 protein over-expression and clinical outcome in breast cancer,"
"Identifying factors associated with falls in postmenopausal breast cancer survivors: A multi-disciplinary approach,"
