Tibor Kovacsovics, M.D.

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Office:: 503 494-5058

Background

Dr. Kovacsovics research focuses on clinical trials with new agents for treatment of acute leukemias.

Selected Publications

"Kinase pathway dependence in primary human leukemias determined by rapid inhibitor screening," Cancer Research (Vol: 73, Issue: 1, Page 285-296) - 2013

"Multiplex high-throughput gene mutation analysis in acute myeloid leukemia," Human Pathology (Vol: 43, Issue: 12, Page 2167-2176) - 2012

"Clofarabine plus cytarabine compared with cytarabine alone in older patients with relapsed or refractory acute myelogenous leukemia: Results from the CLASSIC I trial," Journal of Clinical Oncology (Vol: 30, Issue: 20, Page 2492-2499) - 2012

"RAS mutations in therapy-related acute myeloid leukemia after successful treatment of acute promyelocytic leukemia," Leukemia and Lymphoma (Vol: 53, Issue: 5, Page 999-1002) - 2012

"Outpatient consolidation treatment with clofarabine in a phase 2 study of older adult patients with previously untreated acute myelogenous leukemia," Leukemia and Lymphoma (Vol: 53, Issue: 3, Page 435-440) - 2012

"Prevention and management of asparaginase/pegasparaginase-associated toxicities in adults and older adolescents: Recommendations of an expert panel," Leukemia and Lymphoma (Vol: 52, Issue: 12, Page 2237-2253) - 2011

"Conditioning with Treosulfan and Fludarabine followed by Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies," Biology of Blood and Marrow Transplantation (Vol: 17, Issue: 3, Page 341-350) - 2011

"Value of allogeneic versus autologous stem cell transplantation and chemotherapy in patients with myelodysplastic syndromes and secondary acute myeloid leukemia. Final results of a prospective randomized European intergroup trial," Haematologica (Vol: 95, Issue: 10, Page 1754-1761) - 2010

"RNAi screen for rapid therapeutic target identification in leukemia patients," Proceedings of the National Academy of Sciences of the United States of America (Vol: 106, Issue: 21, Page 8695-8700) - 2009

"Peritoneal tuberculosis after imatinib therapy," Archives of Internal Medicine (Vol: 169, Issue: 3, Page 312-313) - 2009

"Rescue from failed growth factor and/or chemotherapy HSC mobilization with G-CSF and plerixafor (AMD3100): An institutional experience," Bone Marrow Transplantation (Vol: 43, Issue: 12, Page 909-917) - 2009

"Early intensification and autologous stem cell transplantation in patients with systemic AL amyloidosis: A single-centre experience," Annals of Hematology (Vol: 88, Issue: 7, Page 681-685) - 2009

"High-throughput mutational screen of the tyrosine kinome in chronic myelomonocytic leukemia," Leukemia (Vol: 23, Issue: 2, Page 406-409) - 2009

"Outcome of treatment after first relapse in adults with acute lymphoblastic leukemia initially treated by the LALA-94 trial," Leukemia (Vol: 21, Issue: 9, Page 1907-1914) - 2007

"Philadelphia chromosome-positive acute lymphoblastic leukemia: Impact of imatinib treatment on remission induciton and allogeneic stem cell tranplantation," Current Oncology Reports (Vol: 8, Issue: 5, Page 343-351) - 2006

"Long-term complete responses after ¹³¹I-tositumomab therapy for relapsed or refractory indolent non-Hodgkin's lymphoma," British Journal of Cancer (Vol: 94, Issue: 12, Page 1770-1776) - 2006

"Autologous stem cell transplantation in adults with acute lymphoblastic leukemia in first complete remission: Analysis of the LALA-85, -87 and -94 trials," Leukemia (Vol: 20, Issue: 2, Page 336-344) - 2006

"Repeated injections of ¹³¹I-rituximab show patient-specific stable biodistribution and tissue kinetics," European Journal of Nuclear Medicine and Molecular Imaging (Vol: 32, Issue: 8, Page 943-951) - 2005

"Severe pustular eruption associated with imatinib and voriconazole in a patient with chronic myeloid leukemia," Dermatology (Vol: 211, Issue: 4, Page 363-365) - 2005

"Systematic screening at diagnosis of -5/del(5)(q31), -7, or chromosome 8 aneuploidy by interphase fluorescence in situ hybridization in 110 acute myelocytic leukemia and high-risk myelodysplastic syndrome patients: Concordances and discrepancies with conventional cytogenetics," Cancer Genetics and Cytogenetics (Vol: 152, Issue: 1, Page 29-41) - 2004

"Prolonged treatment with rituximab in patients with follicular lymphoma significantly increases event-free survival and response duration compared with the standard weekly Ã— 4 schedule," Blood (Vol: 103, Issue: 12, Page 4416-4423) - 2004

"A template-assembled synthetic protein surface mimetic of the von Willebrand factor A1 domain inhibits botrocetin-induced platelet aggregation," ChemBioChem (Vol: 5, Issue: 6, Page 856-864) - 2004

"Determination of imatinib (GleevecÂ®) in human plasma by solid-phase extraction-liquid chromatography-ultraviolet absorbance detection," Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences (Vol: 803, Issue: 2, Page 285-292) - 2004

"Outcome of treatment in adults with acute lymphoblastic leukemia: Analysis of the LALA-94 Trial," Journal of Clinical Oncology (Vol: 22, Issue: 20, Page 4075-4086) - 2004

"Developing a European network for adult ALL," Hematology Journal (Vol: 5, Issue: SUPPL. 3, Page S46-S52) - 2004