Thomas S. Scanlan, Ph.D.
The current research in the Scanlan Lab is centered broadly in the area of hormone action, with an emphasis on the classic endocrine modulators belonging to the steroid/thyroid family. These hormones coordinate a variety of important physiologic functions in development and homeostasis, and they mediate the regulation with exquisite selectivity. One of the Lab's primary activities is to develop an understanding of the molecular basis of the tissue-selectivity of these hormones using a multidisciplinary approach that involves synthetic chemistry, biochemistry, cell biology, and ultimately
"Intrinsic expression of a multiexon type 3 deiodinase gene controls zebrafish embryo size,"
"Effects of acute microinjections of the thyroid hormone derivative 3-iodothyronamine to the preoptic region of adult male rats on sleep, thermoregulation and motor activity,"
"Erratum: The Synthesis of 13C9-15N-Labeled 3,5-Diiodothyronine and Thyroxine(Synthetic Communications (2013) 43:10 (1439-1446)),"
"NMR-based metabolomics and breath studies show lipid and protein catabolism during low dose chronic T1AM treatment,"
"The synthesis of 13C9-15N-labeled 3,5-diiodothyronine and thyroxine,"