OHSU

Guang Fan, M.D., Ph.D.

Head Shot of Guang Fan

Associate Professor

Email: 
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Lab Phone: 
503-494-2302

Background

Dr. Fan's research interest is in developing sensitive and advanced diagnotic tests for leukemia and lymphoma. Recent publications include:

1. Proteomic Profiling of Mature CD10-Positive B-Cell Lymphomas. Am J Clin Pathol. 2005 Dec; 124(6):920-9.

2. Aberrant Stabilization of c-Myc Protein in Lymphoblastic and Myelogenous Leukemia. Leukemia (2006) Sep;20(9):1572-81.

3. Drug Resistance in B-Cell Chronic Lymphocytic Leukemia: Predictable by In Vitro Evaluation with a Multiparameter Flow Cytometric Cytotoxicity Assay. Cytometry Part B: Clinical Cytometry (2007) 72 (3), 189-195.

4. An open source tool for integrated protein identification and quantitation. Bioinformatics. Bioinformatics. Published on line Sept 25, 2007. http://bioinformatics.oxfordjournals.org/cgi/reprint/btm467v1.

5. The Saga of Jak2 mutations and translocations in hematologic disorders: Pathogenesis, diagnostic & therapeutic prospects, and proposed revision of WHO diagnostic criteria for chronic myeloproliferative disorders. Human Pathology. (2008) 39,795-810.

6. Nuclear expression of Sox11 is highly associated with mantle cell lymphoma but not dependent on t(11;14)(q13;q32) translocation. Modern Pathology. 2010, 23 (1) 105-112. Doi:10.1038/modpathol.2009.140;Published online

7. Immunophenotypic variations of Burkitt lymphoma. AJCP 2010,134(1):127-138

8. Correlation of T-cell immunophenotype between skin biopsy and peripheral blood findings in mycosis fungoides. AJCP 2010,134(5):739-748

9. Association of JAK2 mutation status and cytogenetic abnormalities in myeloproliferative neoplasms and myelodysplastic/myeloproliferative neoplasms. AJCP accepted in Nov 2010.


Selected Publications

"Aberrations of MYC are a common event in B-cell prolymphocytic leukemia," American Journal of Clinical Pathology (Vol: 142, Issue: 3, Page 347-354) - 2014

"Corepressor Rcor1 is essential for murine erythropoiesis," Blood (Vol: 123, Issue: 20, Page 3175-3184) - 2014

"Functional integration of acute myeloid leukemia into the vascular niche," Leukemia - 2014

"Early precursor T-lymphoblastic leukaemia/lymphoma arising from paediatric chronic myeloid leukaemia - unusual lymph node blast crisis," British Journal of Haematology (Vol: 161, Issue: 1, Page 136-139) - 2013

"Kinase pathway dependence in primary human leukemias determined by rapid inhibitor screening," Cancer Research (Vol: 73, Issue: 1, Page 285-296) - 2013

 

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Contact

  Email Guang Fan

503 494-8311