Nabil J. Alkayed, M.D., Ph.D

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Lab Phone: 
503 494-9061


Dr. Alkayed is Professor and Vice Chair for Research of Anesthesiology and PeriOperative Medicine (APOM) at Oregon Health & Science University (OHSU) and holds a joint appointment in Physiology and Pharmacology. He is Director of the newly formed Division of Cerebrovascular Research and Associate Director of the Research Center for Gender-Based Medicine at OHSU. In addition, Dr. Alkayed serves on the Program for Molecular and Cellular Biosciences (PMCB) and the Neuroscience Graduate Program (NGP) at OHSU.Dr. Alkayed is funded through two R01 grants from the National Institute of Neurological Disease and Stroke (NINDS) to study the role of sEH in ischemic brain injury and vascular dysfunction after stroke n postmenopausal females. In addition, he has a grant from the Oregon Alzheimer Disease Center to study the role of sEH in aging-related white matter lesions. Dr. Alkayed sits on the editorial boards of Stroke, The American Journal of Physiology–Heart and Circulation, and the Journal of Cerebral Blood Flow and Metabolism. He is a member of the American Heart Association Brain and Stroke Study Section and the National Institutes of Health Neural Oxidative Metabolism and Death Study Section. Dr. Alkayed grew up in Amman, Jordan. He earned his medical degree from Stavropol State Medical Academy in Russia and a PhD in physiology from the Medical College of Wisconsin in Milwaukee. After completing a postdoctoral research fellowship at Johns Hopkins University, Dr. Alkayed launched his academic career as Assistant Professor of Anesthesiology & Critical Care Medicine at The Johns Hopkins School of Medicine in 1998. He joined OHSU in 2003 as Associate Professor, was promoted to Professor in 2008, and to Vice Chair for Research in 2011.

Selected Publications

"Peroxisomal biogenesis in ischemic brain," Antioxidants and Redox Signaling (Vol: 22, Issue: 2, Page 109-120) - 2015

"A novel HLA-DRα1-MOG-35-55 construct treats experimental stroke," Metabolic Brain Disease (Vol: 29, Issue: 1, Page 37-45) - 2014

"CaMKKβ-Dependent activation of AMP-activated protein kinase is critical to suppressive effects of hydrogen sulfide on neuroinflammation," Antioxidants and Redox Signaling (Vol: 21, Issue: 12, Page 1741-1758) - 2014

"Different immunological mechanisms govern protection from experimental stroke in young and older mice with recombinant TCR ligand therapy," Frontiers in Cellular Neuroscience (Vol: 8, Issue: SEP, Page 1-13) - 2014

"Epoxyeicosatrienoic acids mediate insulin-mediated augmentation in skeletal muscle perfusion and blood volume," American Journal of Physiology - Endocrinology and Metabolism (Vol: 307, Issue: 12, Page E1097-E1104) - 2014



  Email Nabil Alkayed

503 494-8311

Memberships & Associations

American Physiological Society
Society for Neuroscience
Fellow of the American Heart Association Stroke Council
International Soceity of Cerebral Blood Flow and Metabolism
Association of University Anesthesiologists