Owen J.T. McCarty, Ph.D.
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Dr. McCarty received his Ph.D in Chemical & Biomolecular Engineering from Johns Hopkins University with dissertation work focused on the role of platelets in cancer metastasis and thrombosis. As a Wellcome Trust Postdoctoral Fellow, he continued his research in the area of thrombosis, examining the signaling pathways governing platelet cytoskeleton reorganization, at the Department of Pharmacology, Oxford University and Centre for Cardiovascular Sciences, University of Birmingham, UK.
Summary of Current Research
Research InterestsDr. McCarty's research is focused on understanding the interplay between cell biology and fluid mechanics in the cardiovascular system. In particular, his research into the balance between hydrodynamic shear forces and chemical adhesive interactions has great relevance to underlying processes of cancer, cardiovascular disease, and inflammation.Research ProjectsThrombosis and HemostasisResearch GroupsCardiovascular and Blood ResearchVascular Biology and Vascular Tissue Engineering
"A theme series on physical biology in cancer in AJP-cell,"
"CXCR7 expression disrupts endothelial cell homeostasis and causes ligand-dependent invasion,"
"Development of a method to quantify platelet adhesion and aggregation under static conditions,"
"Factor XII inhibition reduces thrombus formation in a primate thrombosis model,"
"Flow-dependent thrombin and fibrin generation in vitro: Opportunities for standardization: Communication from SSC of the ISTH,"