OHSU

Jeff Gold, M.D.

Head Shot of Jeff Gold

Associate Professor

Email: 
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Office: 
503-494-1620

Background

Dr. Gold's main research focus is investigating the role of costimulatory molecules in the innate immune response during polymicrobial sepsis. The lab has previously described an essential role for the costimualtory receptor, CD40, in controlling inflammation in murine polymicrobial sepsis. Currently, the lab will be focusing on the effect of simultaneous inhibition of CD40 and CD80/86 in murine polymicrobial sepsis. This will be done in concert with human trials characterizing the expression profiles of costimualtory receptor and their soluble ligands in humans with sepsis.

Clinically, aside from the treatment of sepsis, Dr. Gold is extremely interested in new protocols for the management of alcohol withdrawal and delirium Tremens in the ICU.


Selected Publications

"Intermittent mechanical tricuspid valve obstruction recognized by central venous pressure tracing and confirmed by transesophageal echocardiography.," Journal of the American College of Cardiology (Vol: 60, Issue: 10, Page e17) - 2012

"The role of cyclooxygenase-2 in mechanical ventilation-induced lung injury," American Journal of Respiratory Cell and Molecular Biology (Vol: 47, Issue: 3, Page 387-394) - 2012

"Interleukin 5 is protective during sepsis in an eosinophil-independent manner," American Journal of Respiratory and Critical Care Medicine (Vol: 186, Issue: 3, Page 246-254) - 2012

"The role of eosinophils in non-parasitic infections," Endocrine, Metabolic and Immune Disorders - Drug Targets (Vol: 11, Issue: 2, Page 165-172) - 2011

"OX40 ligand regulates inflammation and mortality in the innate immune response to sepsis," Journal of Immunology (Vol: 185, Issue: 8, Page 4856-4862) - 2010

 

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Contact

  Email Jeff Gold

503-494-1620

Memberships & Associations

American Foundation for Medical Research
American Thoracic Society
Society of Critical Care Medicine
Fellow, American College of Chest Physicians
International Shock Society