Claudia López, PhD
Claudia López PhD, Director of the Multiscale Microscopy Core and Research Assistant Professor in the Biomedical Engineering Department, operationally oversees the MMC. Dr. López has extensive experience with EM research including Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM), Dual-Beam applications (FIB-SEM) and Serial Block Face Imaging (SBF-SEM). Her formal training is in biochemistry, biophysics and molecular biology and she has worked in the biochemistry-biophysics and microbiology fields for the past 22 years. Her expertise includes the analysis of both biological (cells, viruses, bacteria, particles and tissues) and non-biological materials (hard materials and fabrics) by TEM, SEM and FIB-SEM and she has routinely performed sample preparation (conventional and cryo-processing), EM imaging and image analysis. As part of her research interests Dr. López is developing correlative light and EM techniques for cultured cells and tissues, both for 2D and 3D electron microscopy. Dr. López is responsible for all day-to-day operations in the MMC, including instrument maintenance and overseeing MMC personnel; meeting with investigators to advise, plan and schedule new experiments; providing sample preparation and imaging services; training users; distributing data; explaining results, and billing for services.
Jessica Riesterer, PhD
Jessica Riesterer, Ph.D. works as a Staff Scientist in the Multiscale Microscopy Core. Her expertise is in scanning electron (SEM) and focused ion beam (FIB) microscopy, concentrating on 3D-data acquisition of life and materials sciences applications. She is also interested in CLEM applications. As a materials scientist by trade, Dr. Riesterer brings a unique perspective to life science imaging, and has experience working with biological tissue/cells, glass & ceramics, metals, semiconductors, polymers, and nuclear fuel & storage materials. She also works with the Teneo VolumeScope serial block face imaging (SBFI) tool and brings her former experience developing the technique as a Senior Applications Engineer at FEI Company to the MMC. In addition to working in the MMC, Dr. Riesterer works in the OHSU Center for Spatial Systems Biomedicine as part of the Gray Lab. Her research concentrates on studying several forms of cancer in 3-dimensions to find a phenotype-genotype linkage.
Melissa Williams, MS
Melissa Williams has over 20 years of experience as an electron microscopy research assistant, in part establishing and then managing an electron microscopy facility at Max-Planck-Institut für Verhaltensphysiologie. More recently, Ms. Williams worked as an electron microscopy assistant for both the Immuno EM Core and the Department of Pathology at OHSU before joining the laboratory of Dr. Joe Gray and MMC. In her current position, she has the dual role of supporting EM research conducted in the Gray Lab, as well as supporting MMC facility and Knight Investigators. Ms. Williams has a strong background in standard and microwave assisted sample preparation techniques as well as TEM and SEM imaging. Ms. Williams assists Dr. López in guiding MMC facility users on all parts of EM workflow, from specimen preparation to ultramicrotomy to imaging.
Drew Gingerich is a Research Technician at the Multiscale Microscopy Core. He trains and assists users with use of the Titan Krios, Talos Arctica, and Tecnai transmission electron microscope. Drew is also responsible for day-to-day operations in the MMC including instrument maintenance, general facilities upkeep and development of the tech infrastructure supporting the transmission electron microscopes. Drew has a background in organic chemistry—he completed a thesis and obtained a BA in chemistry from Reed College in 2015—and has hence held the electron in high esteem long before using electron microscopes. Drew taught himself to program after graduating from Reed and subsequently discovered that structural biology research via transmission electron microscopy and single particle analysis merges his interests in science and technology.