Oligo Synthesis

custom oligo and sirna synthesis

Highest quality, fast, reliable custom primers and probes

Most regular primers (<40 nts) need simple desalting (NAP-10) and are ready for pick-up the next day. Modified oligos and labels, the cost of the reagent is the only additional charge
Longmers with good yield out to 150 nucleotides.
siRNA We can synthesize & prepare duplex siRNA for $220, or individual strands for $100 a piece. Minimum order: 4 siRNA oligos (or 2 pairs). NCBI publishes an excellent introduction to RNA interference.
RNA RNA and mixed RNA/DNA and other unusual nucleic acid molecules can be made. Contact Dr. Keller for details.

Did you know?

Synthetic oligos are single stranded with hydroxyl groups (not phosphates) at both termini. To form a duplex with the complement: simply add equimolar amounts to the your buffered solution, heat to well over the Tm, then allow to slowly cool to room temperature on the bench. Store cold.