2011-2012 Series
AUGUST 2011
Thursday, August 11, 2011
Special Seminar: When ion channel meets transporter: Structure and mechanism of a eukaryotic CLC transporter
Liang Feng, Ph.D.
Laboratory of Molecular Neurobiology and Biophysics, Rockefeller University, New York, NY
Host: Eric Gouaux
OCTOBER 2011
October 6, 2011
Phenotypic analysis at single-cell resolution in vivo: The application of mouse genetic mosaic system to brain tumor biology
Hui Zong, Ph.D.
Institute of Molecular Biology, University of Oregon, Eugene
Host: Dick Goodman
October 13, 2011
Melanopsin signaling in the eye
King-Wai Yau, Ph.D.
Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD
Host: Tianyi Mao
October 20, 2011
Molecular constituents of excitatory synaptic transmission in the brain
Susumu Tomita, Ph.D.
Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT
Host: Eric Gouaux
October 27, 2011
Neural signal integration in dendrites and axons in the hippocampus
Nelson Spruston, Ph.D.
Scientific Program Director and Laboratory Head, HHMI Janelia Farm Research Campus, Ashburn, VA
Host: John Adelman
NOVEMBER 2011
November 3, 2011
Substrate-modulated gating dynamics in a sodium-coupled transporter
Scott Blanchard, Ph.D.
Department of Physiology and Biophysics, Weill Medical College of Cornell University, New York, NY
Host: Eric Gouaux
November 17, 2011
The influences of synaptic frequency and glutamate transport on NMDA receptor signaling
Michael Kavanaugh, Ph.D.
Department of Biomedical and Pharmaceutical Sciences,
The University of Montana, Missoula, MT
Host: Craig Jahr
November 28, 2011
Astrocytes, regulated exocytosis, vesicle traffic and fusion pore properties
Robert Zorec, Ph.D.
Institute of Pathological Physiology, University of Ljubljana, Slovenia
Host: Henrique von Gersdorff and Stephen Smith
DECEMBER 2011
December 1, 2011
Synaptic mechanisms underlying the circuit function in the mammalian retina
Joshua Singer, Ph.D.
Departments of Ophthalmology and Physiology, Northwestern University Feinberg School of Medicine, Chicago, IL
Host: Henrique von Gersdorff
December 5, 2011
Joint Seminar with the Jungers Center: In vivo multiphoton calcium imaging of neuronal and astrocytic networks in mouse models of disease
Kishore Kuchibhotla, Ph.D.
Harvard University, Cambridge, MA
Host: Vivek Unni
FEBRUARY 2012
February 2, 2012
Molecular mechanisms underlying the establishment of neuronal connectivity
Alex Kolodkin, Ph.D.
HHMI, The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD
Host: Tianyi Mao
February 9, 2012
Optogenetics, robotic electrophysiology, and other neuroscience tools
Ed Boyden, Ph.D.
MIT Media Lab, McGovern Institute, Depts. of Brain & Cognitive Sciences and Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA
Host: Gary Westbrook
February 16, 2012
Joint Seminar with Physiology & Pharmacology:
Active trans-membrane water cycling: High-resolution NMR detection of life
Charles Springer, Ph.D.
Advanced Imaging Research Center, Knight Cancer Institute, Department of Biomedical Engineering, OHSU, Portland, OR
Host: David Dawson
February 23, 2012
Peptides, peptidases, and peptidomics: New insights into inter- and intracellular signaling
Lloyd Fricker, Ph.D.
Departments of Molecular Pharmacology and Neuroscience, Albert Einstein College of Medicine of Yeshiva University, Bronx, NY
Host: Gary Thomas
MARCH 2012
March 1, 2012
Zinc-mediated synaptic signaling: The role of zinc as a neurotransmitter
Thanos Tzounopoulos, Ph.D.
Departments of Otolaryngology and Neurobiology, Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, PA
Host: John Adelman
March 8, 2012
The structure of a GPCR-G protein complex: Insights into the mechanism of hormone-activated nucleotide exchange
Roger Sunahara, Ph.D.
Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI
Host: John Williams
March 13, 2012
Joint Special Seminar with OHSU Nephrology & Hypertension: Deconstructing the machine: Understanding complex traits using extreme outliers
Richard P. Lifton, M.D., Ph.D.
HHMI, Departments of Genetics and Internal Medicine, Yale University School of Medicine, New Haven, CT
Host: Dick Goodman David Ellison
March 15, 2012
Regulation of cell death by the Bcl-2 family member Mcl-1
Gordon Shore, Ph.D.
Department of Biochemistry, Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada
Host: Gary Thomas
March 30, 2012
Tom Soderling Symposium: A Career in Calcium Signaling
Session I: Intracellular Signaling
John Scott, Ph.D., Cell signaling in space and time
Gary Banker, Ph.D., Microtubule-based motors in neuronal polarity
Randy Hall, Ph.D., Signaling by adhesion G protein-coupled receptors
Hervé Enslen, Ph.D., Tyrosine kinases move from the regulation of cell adhesion to pathogen invasion
Scott Soderling, Ph.D., Actin badly: Modeling disorders associated with abnormal synaptic cytoskeletal signaling
Gary Wayman, Ph.D., Neurotrophic actions of leptin: Local and genetic control of synaptogenesis
Session II: Ca2+-CaM Kinases
Hiroshi Tokumitsu, Ph.D., CaMKK: From enzyme to inhibitor
Takeo Saneyoshi, Ph.D., Functional phospho-proteomics analysis of cellular substrates for CaMKI
Roger Colbran, Ph.D., Modulation of CaMKII by CaMKII-associated proteins
Andres Barria, Ph.D., Trafficking and function of NMDA receptors
Johannes Hell, Ph.D., Role of CaMKII binding to the NMDAR subunit GluN2B in LTP and memory consolidation
John Lisman, Ph.D., CaMKII: a memory molecule
APRIL 2012
April 5, 2012
The role of KSR and RAF kinases in the MAP kinase signaling pathway
Andrey Shaw, M.D.
HHMI, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO
Host: Phil Stork
April 16, 2012
Special Seminar: The emergence of response selectivity in primary visual cortex
Nicholas Priebe, Ph.D.
Section of Neurobiology, School of Biological Sciences, The University of Texas at Austin
Host: Neuroscience Graduate Program and Henrique von Gersdorff
April 17, 2012
Jungers Center Seminar: The changing face of Alzheimer's disease: From early onset families in Colombia to rethinking the basics
Kenneth Kosik, M.D.
Department of Molecular, Cellular and Developmental Biology
University of California, Santa Barbara
Host: Gary Westbrook and the 2012 Neurobiology of Disease Course
April 19, 2012
Bidirectional synaptic plasticity expressed by NMDA receptors
Pablo Castillo, M.D., Ph.D.
Department of Neuroscience, Albert Einstein College of Medicine of Yeshiva University, Bronx, NY
Host: Craig Jahr
April 26, 2012
Mice, men, and microscopes: Visualizing the dynamics of the neuronal orchestra in awake behaving animals
Mark Schnitzer, Ph.D.
HHMI, Department of Biological Sciences, Department of Applied Physics, Stanford University, Stanford, CA
Host: Teresa Nicolson
April 27, 2012
Special Seminar: Growth control and growth-dependent cell cycles in Drosophila
Bruce A. Edgar, Ph.D.
German Cancer Research Center (DKFZ)–Center for Molecular Biology Heidelberg (ZMBH) Alliance, Heidelberg, Germany
Host: Dick Goodman
MAY 2012
May 10, 2012
Mechanisms of motor control and reinforcement learning in the basal ganglia
Anatol Kreitzer, Ph.D.
Gladstone Institute of Neurological Disease, Depts. of Physiology and Neurology, University of California, San Francisco
Host: Larry Trussell
May 15, 2012
Jungers Center Seminar: Mitochondrial dynamics and axon degeneration
Robert H. Baloh, M.D., Ph.D.
Dept. of Neurology: Neuromuscular Medicine, ALS Program, Cedars-Sinai Medical Center, Los Angeles, CA
Host: Gary Westbrook and the 2012 Neurobiology of Disease Course
May 17, 2012
Herbert Memorial Lecture: Novel neural messengers of life and death
Solomon H. Snyder, M.D.
The Solomon H. Snyder Department of Neuroscience,
Johns Hopkins University School of Medicine, Baltimore, MD
Host: Dick Goodman
May 18, 2012
Special Seminar: Synaptic circuit organization of mouse motor cortex
Gordon M. G. Shepherd, M.D., Ph.D.
Department of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, IL
Host: Neuroscience Graduate Program and Henrique von Gersdorff
May 18, 2012
Special Seminar: Native AMPA receptors in the mammalian brain: Insights and surprises from high resolution proteomics
Bernd Fakler, M.D.
Institute of Physiology, University of Freiburg, Freiburg, Germany
Host: John Adelman
JULY 2012
Friday, July 27, 2012
Special Seminar: Spatiotemporal dynamics of opioid neuropeptide signaling in the mammalian brain
Matthew Banghart, Ph.D.
Department of Neurobiology, Harvard Medical School, Boston, MA
Host: John Williams
