This section lists faculty, postdoctoral, research, and administrative positions available in the Vollum Institute at OHSU.
Employment at the Vollum often allows sufficient time for career-enhancing activities, such as attendance at seminars and participation in lab meetings. Many technicians go on to graduate training at OHSU and other top programs. Long term employment opportunities including some with supervisory responsibilities are also available in some laboratories.
OHSU is an equal opportunity affirmative action institution.
The Vollum Institute faculty search for 2016–17 has closed.
For more information, contact:
Gary Westbrook, M.D.
Vollum Institute, L-474
Oregon Health & Science University
3181 SW Sam Jackson Park Road
Portland, OR 97239-3098
For information about postdoctoral positions not listed here, please contact individual faculty members for the particular lab(s) in which you are interested.
A postdoctoral fellow position is available for research focused on understanding how short-term synaptic plasticity affects neural processing. Short-term plasticity dynamically changes the strength of synaptic connections by orders of magnitude, and dramatically alters the input-output transformation of neural circuits. The Jackman lab uses patch-clamp electrophysiology, optogenetics, calcium imaging, and computational modeling to investigate the mechanisms that drive short-term plasticity. Using these techniques we recently discovered that the synaptotagmin isoform Syt7 is responsible for one of the most common forms of short-term plasticity, synaptic facilitation. Facilitation is hypothesized to play fundamental roles in both cognitive and sensory processing. Using Syt7 knockout mice we perform behavior assays and in vivo recordings of neural activity to evaluate how short-term plasticity affects circuit function.
The Jackman lab is located in the Vollum Institute at Oregon Health & Science University in Portland Oregon. Candidates experienced with patch-clamp or in vivo electrophysiology, in vivo calcium imaging, or rodent behavior are particularly encouraged to apply. Apply by emailing a CV and three references to firstname.lastname@example.org.
Haining Zhong Lab
Full time postdoctoral positions are available for examining neuromodulatory signaling in vivo using advanced imaging methods. Based on our previous studies, we can image subcellular signaling events triggered by neuromodulators, such as dopamine, with high spatiotemporal resolutions. This puts us in a unique position to ask unanswered fundamental questions regarding neuromodulation—including what, who, when and how. Our studies focus on the mouse cortex as well as deep brain structures, such as the striatum, in brain slices and in behaving mice. The project is funded by a BRAIN Initiative grant.
The Zhong Lab is located in the Vollum Institute at Oregon Health & Science University. Applicants are expected to have backgrounds in neuroscience, biophysics, cell biology, or a related area, and have experience in at least one of the following areas: electrophysiology, microscopy, or mouse genetics. While cutting-edge research has great potential, it is not easy. Please apply only if you are willing to work hard to compete at the highest scientific level. If interested, please contact Haining Zhong directly at email@example.com.
Henrique von Gersdorff Lab
A full time postdoctoral fellow position is available in the lab of Dr. Henrique von Gersdorff, a member of the Vollum Institute at Oregon Health & Science University (OHSU). The research focuses on auditory and visual sensory synapses; see Dr. von Gersdorff's faculty page for more details and references. Experience in patch-clamping techniques and/or calcium imaging techniques is required; experience in biophysical analysis methods and computer modeling is desirable. Training in methods specific to sensory synapses will be provided by the von Gersdorff lab. Our major interests concern the synaptic physiology of ribbon-type synapses in the vertebrate retina, ribbon-type synapses in the cochlea, and calyx-type synapses in the mammalian auditory brainstem. The applicant must be highly motivated, interactive, and interested in fundamental mechanisms of synaptic transmission at ribbon-type or conventional synapses. Salary is commensurate with experience.
To be considered for this position:
Send CV and names of three references to Dr. Henrique von Gersdorff, The Vollum Institute, L-474, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239-3098 or by email to firstname.lastname@example.org. To be considered an official candidate, please also apply online using IRC54804 at www.ohsujobs.com.
Fred Robinson Lab
A postdoctoral fellow position is available in the laboratory of Dr. Fred Robinson in the Jungers Center for Neurosciences Research. The primary goal for this position is to enhance our understanding of phosphoinositide signaling and endosomal trafficking in myelinating Schwann cells, as the dysregulation of these processes causes hereditary peripheral neuropathy. Using novel genetic mouse models of demyelinating neuropathy, as well as an in vitro myelination assay, the successful candidate will pursue a cell biological investigation of how dysregulation of phosphoinositides leads to abnormal myelination. Toward this end, the successful candidate will employ biochemistry, molecular biology and advanced light microscopy. Individuals with expertise in cell biology, signaling and neuroscience are especially encouraged to apply.
Interested applicants should email their CV to email@example.com.
Gail Mandel Lab
Postdoctoral Research Associate positions are open for complementary studies on the roles of REST during neuronal maturation and glial-neuronal interactions involved in maintaining central nervous system circuitry. The REST repressor protein is a unique regulator of neuronal gene chromatin and we are studying how it changes higher order chromatin architecture and gene expression in individual neurons during aging. We have also launched studies of gene regulation in human neural cells. The Mandel lab is a leader in the study of mouse models for neurological diseases, such as autism spectrum disorders. We recently identified glia as integral components of mature brain circuitry that are affected in neurological disease and are using imaging and electrophysiology, in conjunction with genetics, to pinpoint the defects.
The lab is located in the Vollum Institute at Oregon Health & Science University in Portland. Interested candidates within 4 years of having received their PhD are encouraged to apply. Prior expertise in molecular and cellular biology, or biochemistry, is essential.
To apply, please email CV and contact details of three references to firstname.lastname@example.org.
Soo Lee Lab
Gene Networks in CNS Development
Unraveling the processes that generate the numerous neuronal subtypes and establish their appropriate connections to form a functional CNS is one of the main challenges in neuroscience today. Particularly, decoding the gene regulatory network responsible for neuronal subtype specification is a fundamental step toward understanding the CNS development and advancing methods to generate specific neurons in regenerative medicine.
Our goal is to develop a comprehensive map of the complex gene regulatory networks that direct cell-fate specification and assembly of neuro-circuits. Our major model systems include the spinal cord, which consists of distinct classes of neurons to assemble motor and sensory circuits.
To achieve our goals, we dissect multiple layers of gene regulatory steps that render neuronal cell-fate specification, taking the following steps; to define transcription complexes specifying each neuronal population, to identify their downstream effector genes conferring unique cell-identity, to understand epigenetic strategy orchestrating timely changes on gene transcription, to uncover the molecular mechanism by which the extracellular cues modulate neuronal gene expression, and to generate specific neuronal subtypes from stem cells by applying the developmental gene regulatory strategy that we define. Our study will eventually contribute to the design of a rational strategy to repair damaged neurons and to treat metabolic disorders in the human.
For further details, please visit Soo Lee's lab page.
If you are interested in a position in our lab, please contact Soo Lee directly at email@example.com.
For information about research staff positions not listed here, please contact individual faculty members for the particular lab(s) in which you are interested.
There are no openings at this time.
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