Recent Publications

Blood Advances, January 23, 2018
The human IL-15 superagonist ALT-803 directs SIV-specific CD8+ T cells into B-cells follicles

Nature Medicine, January 15, 2018
Prevention of tuberculosis in rhesus macaques by a cytomegalovirus-based vaccine

Retrovirology, January 9, 2018
Next-generation in situ hybridization approaches to define and quantify HIV and SIV reservoirs in tissue microenvironments

J. Virology, January 2, 2018
Combination Adenovirus and Protein Vaccines Prevent Infection or Reduce Viral Burden after Heterologous Clade C SHIV Mucosal Challenge

J. Virology, January 1, 2018
The Role of MHC-E in T Cell Immunity Is Conserved among Humans, Rhesus Macaques,
and Cynomolgus Macaques

J. Virology, December 20, 2017
Antagonism of the protein kinase R pathway in human cells by rhesus cytomegalovirus

J. Virology, December 20, 2017
Emerging Alphaviruses are Sensitive to Cellular States Induced by a Novel Small
Molecule Agonist of the STING Pathway

Nature Communications, December 15, 2017
Hepatocytic expression of human sodium-taurocholate cotransporting polypeptide enables hepatitis B virus infection of macaques

Nature Communications, November 10, 2017
Allogeneic stem cell transplantation in fully MHC-matched Mauritian cynomolgus macaques recapitulates diverse human clinical outcomes

PLOS, November 9, 2017
Quantitative membrane proteomics reveals a role for tetraspanin enriched microdomains during entry of human cytomegalovirus

J. Virology, November 1, 2017
An Epstein-Barr Virus MicroRNA Blocks Interleukin-1 (IL-1) Signaling by
Targeting IL-1 Receptor 1

mSphere, October 4, 2017
Cloning, Assembly, and Modification of the Primary Human Cytomegalovirus Isolate Toledo by Yeast-Based Transformation-Associated Recombination

J. Virology, October 4, 2017
Full-length isoforms of KSHV LANA accumulate in the cytoplasm of cells undergoing the lytic cycle of replication

JoVE, August 25, 2017
An In Vitro Model for Studying Cellular Transformation by Kaposi Sarcoma

Springer, August 15, 2017
High-Throughput Screening for Identification of Novel Innate Immune Activators

Virology (Hyderabad), July 31, 2017
Modulation of the NFkb Signalling Pathway by Human Cytomegalovirus

Elsevier, July 19, 2017
CD8+ T cell programming by cytomegalovirus vectors: applications in prophylactic and therapeutic vaccination

July 4, 2017
Roles of Non-coding RNAs During Herpesvirus Infection

PLOS, June 19, 2017
Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques

Elsevier, May 12, 2017
Unusual antigen presentation offers new insight into HIV vaccine design

mBio, May 2, 2017
A Novel Agonist of the TRIF Pathway Induces a Cellular State Refractory to Replication of Zika, Chikungunya, and Dengue Viruses

Scientific Reports, April 20, 2017
Human Cytomegalovirus Induces Cellular and Humoral Virus-specific Immune Responses in Humanized BLT Mice

Front Microbiology, April 3, 2017
The Heme Metabolite Carbon Monoxide Facilitates KSHV Infection by Inhibiting TLR4 Signaling in Endothelial Cells

PLOS, March 9, 2017
Zika Virus infection of rhesus macaques leads to viral persistence in multiple

mBio, March 7, 2017
Human Cytomegalovirus MicroRNAs miR-US5-1 and miR-UL112-3p Block Proinflammatory
Cytokine Production in Response to NF-kB-Activating Factors through Direct Downregulation of IKKa and IKKB

Journal of Virology, February 1, 2017
A microRNA screen identifies the Wnt signaling pathway as a regulator of the interferon response during flavivirus infection

American Society for Cell Biology, January 1, 2017
p120-catenin regulates VE-cadherin endocytosis and degradation induced by the Kaposi sarcoma-associated ubiquitin ligase K5

PLOS, December 15, 2016
Peptide Processing Is Critical for T-Cell Memory Inflation and May Be Optimized to Improve Immune Protection by CMV-Based Vaccine Vectors

PLOS, December 7, 2016
Microbial Translocation and Inflammation Occur in Hyperacute Immunodeficiency Virus Infection and Compromise Host Control of Virus Replication

The Journal of Infectious Diseases, December 5, 2016
Animal Models of Chikungunya Virus Infection and Disease

Nature Communications, November 30, 2016
Additives for vaccine storage to improve thermal stability of adenoviruses from hours to months

eLife, November 22, 2016
A Herpesviral induction of RAE-1 NKG2D ligand expression occures through release of HDAC mediated repression

Methods in Molecular Biology, November 22, 2016
Analysis of Viral and Cellular MicroRNAs in EBV-Infected Cells

PLOS, November 9, 2016
Cross-Species Rhesus Cytomegalovirus Infection of Cynomolgus Macaques

Immunity, October 18, 2016
Antiviral CD8+ T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion

Mucosal Immunology - Nature, October 19, 2016
MR1-restricted Mucosal-associated invariant T (MAIT) cells respond to mycobacterial vaccination and infection in nonhuman primates

Journal of Virology, October 15, 2016
Japanese Macaque Rhadinovirus Encodes a Viral MicroRNA Mimic of the miR-17 Family

PLOS, October 13, 2016
Dysregulated TGF-β Production Underlies the Age-Related Vulnerability to Chikungunya Virus

Mechanisms of Ageing and Development, September 1, 2016
A new perspective of the structural complexity of HCMV-specific T-cell responses

PLOS, August 31, 2016
Natural Killer Cell Evasion Is Essential for Infection by Rhesus Cytomegalovirus

The Journal of Immunology, August 15, 2016
Effect of Anti-IL-15 Administration on T Cell and NK Cell Homeostasis in Rhesus Macaques

PNAS, August 2, 2016
Viral binding-induced signaling drives a unique and extended intracellular trafficking pattern during infection of primary monocytes

PLOS, July 29, 2016
Cytomegalovirus Infection of the Rat Developing Brain In Utero Prominently Targets Immune Cells and Promotes Early Microglial Activation

PLOS, June 2, 2016
Humans Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation

The Journal of Immunology, April 1, 2016
Achieving Potent Autologous Neutralizing Antibody Responses against Tier 2 HIV-1 Viruses by Strategic Selection of Envelope Immunogens

Nature, March 21, 2016
Early short-term treatment with neutralizing human monoclonal antibodies halts SHIV infection in infant macaques

American Society for Microbiology, March 1, 2016
Complex Interplay of the UL136 Isoforms Balances Cytomegalovirus Replication and Latency

Science, January 21, 2016
Broadly targeted CD8+ T cell responses restricted by major histocompatibility complex E

Journal of Immunology, September 28, 2015
Effect of IL-7 Therapy on Naive and Memory T Cell Homeostasis in Aged Rhesus Macaques

Current Option in Virology, June 25, 2015
Humanized mouse models of human cytomegalovirus infection

Journal of Virology, June 17, 2015
The ORF61 protein encoded by Simian Varicella Virus and Varicella Zoster Virus inhibits NFκB signaling by interfering with IκBα degradation

American Society For Microbiology, June 4, 2015
Kaposi Sarcoma Herpesvirus Induces HO-1 during De NovoInfection of Endothelial Cells via Viral miRNA-Dependent and -Independent Mechanisms

PLOS Pathogens, May 14, 2015
Varicella Viruses Inhibit Interferon-Stimulated JAK-STAT Signaling through Multiple Mechanisms

Nature, January 19, 2015
B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers

Nature Medicine, January 15, 2015
HIV: Seeking ultimate victory

Virology, November 19, 2014
A simian hemorrhagic fever virus isolate from persistently infected baboons efficiently induces hemorrhagic fever disease in Japanese macaques

Nature, November 13, 2014
Boosting adjuvants – NIH prods industry to develop new vaccine adjuvants

Journal of Virology, November 5, 2014
Short Conserved Sequences of HIV-1 Are Highly Immunogenic and Shift Immunodominance

mBio, October 28, 2014
Human Cytomegalovirus-Encoded pUL7 Is a Novel CEACAM1-Like Molecule Responsible for Promotion of Angiogenesis

Virology Reports, October 22, 2014
Full genome sequence analysis of a novel adenovirus of rhesus macaque origin indicates a new simian adenovirus type and species

Nature Medicine, October 21, 2014
B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers

Nature Reviews Microbiology, October 8, 2014
Novel vaccine vectors for HIV-1

Embo Reports, June 30, 2014
Are effector memory T cells the key to an effective HIV/AIDS vaccine?