Research Resources

Complex Trait Community 2015 Meeting

The Complex Trait Community (CTC) 2015 Meeting was held June 8th - 11th in Portland, Oregon USA. Details concerning the meeting appear at the CTC website. and PARC PI Shannon McWeeney.

 

Animal Models

The Portland Alcohol Research Center (PARC) utilizes many genetic animal models. Mouse genetic models developed locally by PARC researchers are now available to the broader research community.

Go to the Animal Models page

 

Data Sharing

The PARC submits data to established and centralized archives according to data type. We continue in-house to integrate and store larger collections of data that are available to PARC researchers. These data may be made available to outside investigators upon request. 

Go to the Data Sharing page

 

High-Confidence Strain Specific Splicing (SSS) Events Found within Collaborative Cross (CC) Founder Strains

The CC is a large panel of genetically diverse recombinant inbred mouse strains specifically designed to provide a systems genetics resource for the study of complex traits.  The founder strains include five classical inbred laboratory strains {C57BL/6 (B6), 129S1/SvlmJ (129), A/J (AJ), NOD/LtJ (NOD), and NZO/HILtJ (NZO)} and three wild-derived strains {CAST/EiJ (CAST), PWK/PhJ (PWK) and WSB/EiJ (WSB)}.  Through deep transcriptome sequencing, a large number of high-confidence SSS events were identified within each strain.  High-confidence SSS events are defined as exon-exon junctions that 1) are uniquely found in one strain, 2) had a read coverage ≥ 10 and 3) are defined by a canonical splice site.

Download High-Confidence SSS excel file

 

Library

While the PARC is primarily engaged in pre-clinical research, we field a variety of requests for information.  In order to be responsive to the wider community, the Library keeps on hand local referral information and general publications from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the National Institute on Drug Abuse (NIDA). These items have been especially valuable when the PARC responds to requests for clinical information from private individuals, alcohol & drug treatment clinicians, and clinicians from other specialties.  The Library also holds alcohol epidemiological reports, assessment and treatment guides, statistical references, and outreach and educational materials such as NIH curricula focused on addictions. These resources have been beneficial to PARC investigators and students, particularly as they translate the salience of their research to the public in the context of broader addiction issues. 

Go to the Library page