OHSU

DNA & RNA Extraction & Purification

The OCTRI Core Laboratory provides extract and purify DNA and RNA. DNA can be purified from various sources including whole blood, lymphocytes, Guthrie card blood spots, tissues and saliva using various extraction and purification methodologies.

RNA can be isolated from whole blood, lymphocytes and numerous tissue sources.

Degradation of RNA must be eliminated during the collection procedures. Various methods such as the use of Paxgene blood collection tubes and RNA stabilization solutions such as RNA-later can be used to protect RNA prior to purification and quantification.