The OHSU Blood-Brain Barrier and Neuro-Oncology Program conducts innovative patient-oriented research in all aspects of imaging and therapy of brain tumors. New discoveries from the BBB program are creating hope for detection and treatment of these horrible cancers. Our goal is to translate cutting-edge research from the benchtop to the clinic to improve neuro-oncological outcomes for patients.
Clinical research in the BBB Program is headed by Nancy D. Doolittle, R.N., Ph.D., Associate Professor in the Department of Neurology.
- Novel therapeutic approaches in brain tumors, including BBB disruption chemotherapy, monoclonal antibodies, and anti-angiogenic agents.
- New magnetic resonance imaging agents and technology for detecting and characterizing brain tumors and neurological lesions.
- Chemoprotection to reduce the ototoxicity of chemotherapy.
Basic Science and preclinical research in the BBB Program is headed by Leslie L. Muldoon, Ph.D., Associate Professor in the Department of Neurology.
- Novel therapeutics and treatment approaches in brain tumor models.
- Chemoprotection to reduce chemotherapy side effects
- Dynamic MRI and other new imaging techniques in animal models.