OHSU

Publications


 

2014

Austin D, Cross RM, Hayes T, Kaye J. Regularity and predictability of human mobility in personal space. PLoS One 9:e90256, 2014.  PMC3937357.

Davis M, Currey J, Howk S, DeSordi M, Boise L, Fagnan L, Vuckovic N. Qualitative Study of Rural Primary Care Clinician Views on Remote Monitoring Technologies. Journal of Rural Health, 2014. 

Fonareva I, Oken B. Physiological and functional consequences of caregiving for relatives with dementia. International Psychogeriatrics. International Psychogeriatrics 10:1-23, 2014. 

Gray N, Morré J, Kelley J, Maier C, Stevens J, J Q, Soumyanath A. Caffeoylquinic Acids in Centella asiatica Protect against Amyloid-β Toxicity. Journal of Alzheimer's Disease, Forthcoming, 2014. 

Harris CJ, Voss K, Murchison C, Ralle M, Frahler K, Carter R, Rhoads A, Lind B, Robinson E, Quinn JF. Oral Zinc Reduces Amyloid Burden in Tg2576 Mice. Journal of Alzheimer's Disease, 2014. 

Howieson D, Mattek N, Dodge H, Erten-Lyons D, Zitzelberger T, Kaye J. Significance and stability of subjective memory complaints in older adults. Alzheimer's & Dementia, Forthcoming, 2014. 

Kaye J, Mattek N, Dodge HH, Campbell I, Hayes T, Austin D, Hatt W, Wild K, Jimison H, Pavel M. Unobtrusive measurement of daily computer use to detect mild cognitive impairment. Alzheimers Dement 10:10-17, 2014. PMC23688576.

Miller L, Dieckmann N, Mattek N, Lyons K, Kaye J. Social Activity Decreases Risk of Placement in a Long-Term Care Facility for a Prospective Sample of Community-Dwelling Older Adults. Research in Gerontological Nursing:1-7, Forthcoming, 2014.

Shinto L, Quinn J, Montine T, Dodge H, Woodward W, Baldauf-Wagner S, Waichunas D, Bumgarner L, Bourdette D, Silbert L, Kaye J. A Randomized Placebo-Controlled Pilot Trial of Omega-3 Fatty Acids and Alpha Lipoic Acid in Alzheimer’s Disease. Journal of Alzheimer’s Disease 38:111-120, 2014.  PMC3886557.

Stark A, Shafran I, Kaye J. Inferring social nature of conversations from words:  Experiments on a corpous of everyday telephone conversations. Comuter Speech and Language 28:224-239, 2014. 

Theilke S, Mattek N, Hayes T, Dodge H, Quinones A, Austin D, Petersen J, Kaye J. Associations between observed in-home Activities, Behaviors and Self-Reported Low Mood in Community-Dwelling Older Adults. Journal of the American Geriatrics Society, , Forthcoming, 2014. 

Thielke S, Mattek N, Hayes T, Dodge H, Quinones A, Austin  D, Petersen J, Kaye J. Brief Report:  Associations Between Observed In-Home Behaviors and Self-Reported Low Mood in Community-Dwelling Older Adults. Journal of the American Geriatrics Society, Forthcoming, 2014. 

Wertheimer A, Bennett M, Park B, Uhrlaub J, Martinez C, Pulko V, Currier N, Nikolich-Zugich, D, Kaye J, Nikolich-Zugich J. Aging and cytomegalovirus (CMV) infection differentially and jointly affect distinct circulating T cell subsets in humans. Journal of Immunology, 2014. 

2013

Beattie ZT, Hayes TL, Guilleminault C, Hagen CC. Accurate scoring of the apnea-hypopnea index using a simple non-contact breathing sensor. Journal of Sleep Research 22:356-362, 2013.  PMC3641178.

Boise L, Wild K, Mattek N, Ruhl M, Dodge H, Kaye J. Willingness to share data and privacy concerns of Older Adults after exposure to unobtrusive In-home Monitoring. Gerontechnology 11:428-435, 2013.  PMC3604979.

Bowman G, Dodge H, Mattek N, Barbey A, Silbert L, Shinto L, Howieson D, Kaye J, Quinn J. Plasma omega 3 PUFA and white matter mediated executive decline in older adults.  . Frontiers in Aging Neuroscience 5, 2013.  PMC3863786.

Davis M, Freeman M, Kaye J, Vuckovic N, Buckley D. A systematic review of clinician and staff views of the acceptability and feasibility of incorporating remote monitoring technologies into primary care. Telemedicine and e-Health, Forthcoming, 2013.
Dodge H, Ybara O, Kaye J. Tools for advancing research into social networks and cognitive functions in older adults. International Psychogeriatrics International Psychogeriatrics 23:1-7, 2013.

Eskildsen SF, Coupe P, Garcia-Lorenzo D, Fonov V, Pruessner JC, Collins DL. Prediction of Alzheimer's disease in subjects with mild cognitive impairment from the ADNI cohort using patterns of cortical thinning. Neuroimage 65:511-521, 2013.   

Fjell A, McEvoy L, Holland D, Dale A, Walhovd K. Brain changes in older adults at very low risk for Alzheimer's disease. Journal of Neuroscience 33:8237-8242, 2013.  PMC3570420
Fonareva I, Oken B. Physiological and functional consequences of caregiving for relatives with dementia. International Psychogeriatrics. International Psychogeriatrics, Forthcoming, 2013.

Frisoni G, Bocchetta M, Chételat G, Rabinovici G, de Leon M, Kaye J, Reiman E, Scheltens P, Barkhof F, Black S, Brooks D, Carrillo M, Fox N, Herholz K, Nordberg A, Jack C, Jagust W, Johnson K, Rowe C, Sperling R, Thies W, Wahlund L, Weiner M, Pasqualetti P, DeCarli C. Imaging Markers for Alzheimer’s Disease: Which versus How. Neurology 81:5, 2013.  PMC3776529.

Gray KR, Aljabar P, Heckemann RA, Hammers A, Rueckert D. Random forest-based similarity measures for multi-modal classification of Alzheimer's disease. Neuroimage 65:167-175, 2013.  PMC3516432.
Hayes T, Riley T, Mattek N, Pavel M, Kaye J. Sleep Habits in Mild Cognitive Impairment. Alzheimer Disease and Associated Disorders, Forthcoming, 2013.

Hogarth P, Gregory A, Kruer MC, Sanford L, Wagoner W, Natowicz MR, Egel RT, Subramony SH, Goldman JG, Berry-Kravis E, Foulds NC, Hammans SR, Desguerre I, Rodriguez D, Wilson C, Diedrich A, Green S, Tran H, Reese L, Woltjer RL, Hayflick SJ. New NBIA subtype: genetic, clinical, pathologic, and radiographic features of MPAN. Neurology 80:268-275, 2013.  PMC3589182.

Holton P, Ryten M, Nalls M, Trabzuni D, Weale ME, Hernandez D, Crehan H, Gibbs JR, Mayeux R, Haines JL, Farrer LA, Pericak-Vance MA, Schellenberg GD, Ramirez-Restrepo M, Engel A, Myers AJ, Corneveaux JJ, Huentelman MJ, Dillman A, Cookson MR, Reiman EM, Singleton A, Hardy J, Guerreiro R, Apostolova LG, Arnold SE, Baldwin CT, Barber R, Barmada MM, Beach TG, Beecham GW, Beekly D, Bennett DA, Bigio EH, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Burke JR, Buros J, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carney RM, Carrasquillo MM, Carroll SL, Chui HC, Clark DG, Cotman CW, Crane PK, Crocco EA, Cruchaga C, Cummings JL, De Jager PL, DeCarli C, DeKosky ST, Demirci FY, Diaz-Arrastia R, Dick M, Dickson DW, Duara R, Ellis WG, Ertekin-Taner N, Evans D, Faber KM, Fallon KB, Farlow MR, Ferris S, Foroud TM, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Goate AM, Graff-Radford NR, Green RC, Growdon JH, Hakonarson H, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jarvik GP, Jicha GA, Jin LW, Jun G, Kamboh MI, Karlawish J, Karydas A, Kauwe JS, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer P, Kukull WA, Lah JJ, Larson EB, Levey AI, Lieberman AP, Lopez OL, Lunetta KL, Mack WJ, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Morris JC, Naj AC, Nowotny P, Parisi JE, Peskind E, Petersen RC, Poon WW, Potter H, Quinn JF, Raj A, Rajbhandary RA, Raskind M, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rogaeva E, Rosenberg RN, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Shelanski ML, Smith CD, Sonnen JA, Spina S, St George-Hyslop P, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Tsuang DW, Valladares O, Van Deerlin VM, Vardarajan BN, Vinters HV, Vonsattel JP, Wang LS, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL, Wright CB, Younkin SG. Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci. Ann Hum Genet 77:85-105, 2013.  PMC3578142.

Huckans M, Hutson L, Twamley E, Jak A, Kaye J, Storzbach D. Efficacy of Cognitive Rehabilitation Therapies for Mild Cognitive Impairment (MCI) in Older Adults: Working Toward a Theoretical Model and Evidence-Based Interventions. Neuropsychol Rev 23:63-80, 2013.  PMC3640648.

Katsumata Y, Todoriki H, Higashiuesato Y, Yasura S, Ohya Y, Willcox DC, Dodge HH. Very old adults with better memory function have higher low-density lipoprotein cholesterol levels and lower triglyceride to high-density lipoprotein cholesterol ratios: KOCOA Project. Journal of Alzheimer's Disease 34:273-279, 2013.  PMC3586553.

Kaye J, Dodge H, Hayes T, Mattek N, Howieson D, Austin D, H J, Pavel M. Person-specific change in home computer use predicts the development of mild cognitive impairment (MCI). In: AAIC, 2013.

Klein EP, Kaye J. Dementia specialists and early adoption of amyloid imaging. Journal of Alzheimer's Disease 33:445-450, 2013.  PMC3640311.

Kurtz T, Mogle J, Sliwinski MJ, Hofer SM. Individual differences in task-specific paired associates learning in older adults: the role of processing speed and working memory. Exp Aging Res 39:493-514, 2013.  PMC3891359.

Linnertz C, Anderson L, Gottschalk W, Crenshaw D, Lutz M, Allen J, Saith S, Mihovilovic M, Burke J, Welsh-Bohmer K, Roses A, Chiba-Falek O. The cis-regulatory effect of an Alzheimer’s disease-associated poly-T locus on expression of TOMM40 and apolipoprotein E genes. Alzheimer's and Dementia, Forthcoming, 2013.

Liu Y, Mattila J, Ruiz MA, Paajanen T, Koikkalainen J, van Gils M, Herukka SK, Waldemar G, Lotjonen J, Soininen H. Predicting AD conversion: comparison between prodromal AD guidelines and computer assisted PredictAD tool. PLoS One 8:e55246, 2013.  PMC3570420.

Martinez-Murcia FJ, Gorriz JM, Ramirez J, Puntonet CG, Illan IA. Functional activity maps based on significance measures and Independent Component Analysis. Comput Methods Programs Biomed 111:255-268, 2013.

Millard SP, Lutz F, Li G, Galasko DR, Farlow MR, Quinn JF, Kaye JA, Leverenz JB, Tsuang D, Yu CE, Peskind ER, Bekris LM. Association of cerebrospinal fluid Abeta with A2M gene in cognitively normal subjects. Neurobiology of Aging, 2013.  PMC3859300.

Miller JA, Woltjer RL, Goodenbour JM, Horvath S, Geschwind DH. Genes and pathways underlying regional and cell type changes in Alzheimer's disease. Genome Med 5:48, 2013.  PMC3706780.

Miyashita A, Koike A, Jun G, Wang LS, Takahashi S, Matsubara E, Kawarabayashi T, Shoji M, Tomita N, Arai H, Asada T, Harigaya Y, Ikeda M, Amari M, Hanyu H, Higuchi S, Ikeuchi T, Nishizawa M, Suga M, Kawase Y, Akatsu H, Kosaka K, Yamamoto T, Imagawa M, Hamaguchi T, Yamada M, Moriaha T, Takeda M, Takao T, Nakata K, Fujisawa Y, Sasaki K, Watanabe K, Nakashima K, Urakami K, Ooya T, Takahashi M, Yuzuriha T, Serikawa K, Yoshimoto S, Nakagawa R, Kim JW, Ki CS, Won HH, Na DL, Seo SW, Mook-Jung I, St George-Hyslop P, Mayeux R, Haines JL, Pericak-Vance MA, Yoshida M, Nishida N, Tokunaga K, Yamamoto K, Tsuji S, Kanazawa I, Ihara Y, Schellenberg GD, Farrer LA, Kuwano R. SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians. PLoS One 8:e58618, 2013.  PMC3614978.

Nation D, Edland S, Bondi M, Salmon D, Delano-Wood L, Peskind E, Quinn J, Galasko D. Pulse pressure is associated with Alzheimer biomarkers in cognitively normal older adults? Neurology 81:2024-2027, 2013.  PMC3854831.

Nikolich-Zugich J, Bennett M, Park B, Currier N, Uhrlaub J, Vesnam P, Martinez C, Kaye J, Wertheimer A. Aging and cytomegalovirus (CMV) infection differentially and jointly affect distinct circulating T cell subsets in humans. Journal of Immunology, Forthcoming, 2013. 

Pavel M, Jimison HB, Wactlar HD, Hayes TL, Barkis W, Skapik J, Kaye J. The role of technology and engineering models in transforming healthcare. IEEE Rev Biomed Eng 6:156-177, 2013.

Petersen J, Austin D, Kaye J, Pavel M, Hayes T. Unobtrusive in-home detection of time spent out-of-home with applications to loneliness and physical activity. IEEE Journal of Biomedical and Health Informatics, Forthcoming, 2013.

Quinn JF. Biomarkers for Alzheimer's disease: showing the way or leading us astray? Journal of Alzheimer's Disease 33:S371-376, 2013.  PMC3587291.

Rajagopalan P, Toga AW, Jack CR, Weiner MW, Thompson PM. Fat-mass-related hormone, plasma leptin, predicts brain volumes in the elderly. NeuroReport 24:58-62, 2013.  PMC3635486.

Ramaker JM, Swanson TL, Copenhaver PF. Amyloid precursor proteins interact with the heterotrimeric G protein Go in the control of neuronal migration. J Neurosci 33:10165-10181, 2013.  3682380.

Rana R, Austin D, Jacobs P, Karunanithi M, Kaye J. Passive In-home Estimation of Gait Velocity From Motion Sensors. Forthcoming, 2013. 

Reitz C, Jun G, Naj A, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T, Ertekin-Taner N, Logue M, Baldwin CT, Green RC, Barnes LL, Cantwell LB, Fallin MD, Go RC, Griffith P, Obisesan TO, Manly JJ, Lunetta KL, Kamboh MI, Lopez OL, Bennett DA, Hendrie H, Hall KS, Goate AM, Byrd GS, Kukull WA, Foroud TM, Haines JL, Farrer LA, Pericak-Vance MA, Schellenberg GD, Mayeux R. Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E 4,and the risk of late-onset Alzheimer disease in African Americans. JAMA: The Journal of the American Medical Association 309:1483-1492, 2013.  PMC3667653.

Reitz C, Mayeux R. TREM2 and neurodegenerative disease. N Engl J Med 369:1564-1565, 2013.

Reitz C, Tosto G, Vardarajan B, Rogaeva E, Ghani M, Rogers RS, Conrad C, Haines JL, Pericak-Vance MA, Fallin MD, Foroud T, Farrer LA, Schellenberg GD, George-Hyslop PS, Mayeux R. Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP). Translational Psychiatry 3:e256, 2013.  PMC3669917.

Ridge P, Mukherjee S, Crane P, Kauwe J, Consortium AsDG. Alzheimer's disease: Analyzing the missing heritability. PLoS One, Forthcoming, 2013.

Rosso AL, Studenski SA, Chen WG, Aizenstein HJ, Alexander NB, Bennett DA, Black SE, Camicioli R, Carlson MC, Ferrucci L, Guralnik JM, Hausdorff JM, Kaye J, Launer LJ, Lipsitz LA, Verghese J, Rosano C. Aging, the central nervous system, and mobility. J Gerontol A Biol Sci Med Sci 68:1379-1386, 2013.  PMC3805295.

Scimemi A, Meabon JS, Woltjer RL, Sullivan JM, Diamond JS, Cook DG. Amyloid-beta1-42 slows clearance of synaptically released glutamate by mislocalizing astrocytic GLT-1. J Neurosci 33:5312-5318, 2013.

Tong T, Wolz R, Coupe P, Hajnal JV, Rueckert D. Segmentation of MR images via discriminative dictionary learning and sparse coding: application to hippocampus labeling. Neuroimage 76:11-23, 2013.

Tsuang D, Leverenz JB, Lopez OL, Hamilton RL, Bennett DA, Schneider JA, Buchman AS, Larson EB, Crane PK, Kaye JA, Kramer P, Woltjer R, Trojanowski JQ, Weintraub D, Chen-Plotkin AS, Irwin DJ, Rick J, Schellenberg GD, Watson GS, Kukull W, Nelson PT, Jicha GA, Neltner JH, Galasko D, Masliah E, Quinn JF, Chung KA, Yearout D, Mata IF, Wan JY, Edwards KL, Montine TJ, Zabetian CP. APOE 4 Increases Risk for Dementia in Pure Synucleinopathies. JAMA Neurol 70:223-228, 2013.  PMC3580799.

Umegaki H, Takechi H, Dodge HH. Care for Alzheimer's Disease. Int J Alzheimers Dis 2013:516852, 2013.  PMC3654367.

Wild K, Mattek N, Stone B, Kaye J. Self-reported activity in older adults: Challenges and innovations. In: Alzheimer Association International Conference. July ed. Boston, MA: Alzheimer's & Dementia, 2013: P342.

Wu X, Li J, Ayutyanont N, Protas H, Jagust W, Fleisher A, Reiman E, Yao L, Chen K. The receiver operational characteristic for binary classification with multiple indices and its application to the neuroimaging study of Alzheimer's disease. IEEE/ACM Trans Comput Biol Bioinform 10:173-180, 2013.

Wyman BT, Harvey DJ, Crawford K, Bernstein MA, Carmichael O, Cole PE, Crane PK, DeCarli C, Fox NC, Gunter JL, Hill D, Killiany RJ, Pachai C, Schwarz AJ, Schuff N, Senjem ML, Suhy J, Thompson PM, Weiner M, Jack CR, Jr. Standardization of analysis sets for reporting results from ADNI MRI data. Alzheimers Dement 9:332-337, 2013.

2012

Aggarwal NT, Tripathi M, Dodge HH, Alladi S, Anstey KJ. Trends in Alzheimer's disease and dementia in the asian-pacific region. Interntational Journal of Alzheimers Disease 2012:171327, 2012.  PMC3523465.

Anderson V, Lenar D, Berryhill P, Quinn J, Kaye J, Rooney W. Quantitative 7T detection of gadoteridol in the ventricles of the aging human brain Proceedings of the International Society for Magentic Resonane in Medicine 20:3760, 2012.  PMC Journal in Process.

Bakken TE, Roddey JC, Djurovic S, Akshoomoff N, Amaral DG, Bloss CS, Casey BJ, Chang L, Ernst TM, Gruen JR, Jernigan TL, Kaufmann WE, Kenet T, Kennedy DN, Kuperman JM, Murray SS, Sowell ER, Rimol LM, Mattingsdal M, Melle I, Agartz I, Andreassen OA, Schork NJ, Dale AM. Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. Proc Natl Acad Sci U S A 109:3985-3990, 2012.  PMC3309762.

Bekris L, Lutz F, Li G, Galasko D, Farlow M, Quinn J, Kaye J, Leverenz J, Tsuang D, Montine T, Peskind E, Yu C. ADAM10 expression and promoter haplotype in Alzheimer's disease. Neurobiology of Aging 33:2229e2221-2229e2229, 2012.  PMC3391324.

Bekris LM, Millard S, Lutz F, Li G, Galasko DR, Farlow MR, Quinn JF, Kaye JA, Leverenz JB, Tsuang DW, Yu CE, Peskind ER. Tau phosphorylation pathway genes and cerebrospinal fluid tau levels in Alzheimer's disease. Am J Med Genet B Neuropsychiatr Genet 159B:874-883, 2012.

Bjorklund NL, Reese LC, Sadagoparamanujam VM, Ghirardi V, Woltjer RL, Taglialatela G. Absence of amyloid beta oligomers at the postsynapse and regulated synaptic Zn2+ in cognitively intact aged individuals with Alzheimer's disease neuropathology. Mol Neurodegener 7:23, 2012.  PMC3403985.

Bonner-Jackson A, Okonkwo O, Tremont G, Initiative AsDN. Apolipoprotein E epsilon2 and functional decline in amnestic mild cognitive impairment and Alzheimer disease. Am J Geriatr Psychiatry 20:584-593, 2012.  PMC3188382.

Bowman GL. Ascorbic acid, cognitive function, and Alzheimer's disease: A current review and future direction. Biofactors 38:114-122, 2012.

Bowman GL, Kaye JA, Quinn JF. Dyslipidemia and blood-brain barrier integrity in Alzheimer's disease. Curr Gerontol Geriatr Res 2012:184042, 2012.  PMC3359662.

Bowman GL, Silbert LC, Howieson D, Dodge HH, Traber MG, Frei B, Kaye JA, Shannon J, Quinn JF. Nutrient biomarker patterns, cognitive function, and MRI measures of brain aging. Neurology 78:241-249, 2012.  PMC3280054.

Chu C, Hsu AL, Chou KH, Bandettini P, Lin C. Does feature selection improve classification accuracy? Impact of sample size and feature selection on classification using anatomical magnetic resonance images. Neuroimage 60:59-70, 2012.

Damoiseaux JS, Seeley WW, Zhou J, Shirer WR, Coppola G, Karydas A, Rosen HJ, Miller BL, Kramer JH, Greicius MD. Gender modulates the APOE epsilon4 effect in healthy older adults: convergent evidence from functional brain connectivity and spinal fluid tau levels. Journal of Neuroscience 32:8254-8262, 2012.  PMC3394933.

Desikan RS, McEvoy LK, Thompson WK, Holland D, Brewer JB, Aisen PS, Sperling RA, Dale AM. Amyloid-beta--associated clinical decline occurs only in the presence of elevated P-tau. Archives of Neurology 69:709-713, 2012.  PMC3423526.

Dodge HH, Mattek NC, Austin D, Hayes TL, Kaye JA. In-home walking speeds and variability trajectories associated with Mild Cognitive Impairment. Neurology 78:1946-1952, 2012.  PMC3369505.

Erten-Lyons D, Dodge H, Woltjer R, Silbert L, Howieson D, Kramer P, Kaye J. Neuropathological Basis of Age-Associated Brain Atrophy. Archives of Neurology, Forthcoming, 2012.  NIHMS#440270.

Erten-Lyons D, Sherbakov LO, Piccinin AM, Hofer SM, Dodge HH, Quinn JF, Woltjer RL, Kramer PL, Kaye JA. Review of selected databases of longitudinal aging studies. Alzheimers and Dementia 8:584-589, 2012.  PMC3483563.

Fonareva I, Amen A, Ellison R, Oken B. Differences in stress-related ratings between research center and home environments in dementia caregivers using ecological momentary assessment. International Psychogeriatrics 24:90-98, 2012.  PMC3353126.

Fried-Oken M, Rowland C, Daniels D, Dixon M, Fuller B, Mills C, Noethe G, Small J, Still K, Oken B. AAC to Support Conversation in Persons with Moderate Alzheimer's Disease. Augment Altern Commun 28:219-231, 2012.

Gagyi E, Kormos B, Castellanos KJ, Valyi-Nagy K, Korneff D, LoPresti P, Woltjer R, Valyi-Nagy T. Decreased oligodendrocyte nuclear diameter in Alzheimer's disease and Lewy body dementia. Brain Pathology 22:803-810, 2012.  PMC Journal in Process.

Galasko DR, Peskind E, Clark CM, Quinn JF, Ringman JM, Jicha GA, Cotman C, Cottrell B, Montine TJ, Thomas RG, Aisen P. Antioxidants for Alzheimer Disease: A Randomized Clinical Trial With Cerebrospinal Fluid Biomarker Measures. Archives of Neurology, 2012.

Gibbons C, Oken B, Fried-Oken M. Augmented input reveals word deafness in a man with frontotemporal dementia. Behav Neurol 25:151-154, 2012.  PMC3552095.

Haley GE, Berteau-Pavy F, Berteau-Pavy D, Raber J. Novel image-novel location object recognition task sensitive to age-related cognitive decline in nondemented elderly. Age (Dordr) 34:1-10, 2012.  PMC3260359.

Han SD, Gruhl J, Beckett L, Dodge HH, Stricker NH, Farias S, Mungas D. Beta amyloid, tau, neuroimaging, and cognition: sequence modeling of biomarkers for Alzheimer's Disease. Brain Imaging Behav, 2012.

Holland D, Desikan RS, Dale AM, McEvoy LK. Rates of decline in Alzheimer disease decrease with age. PLoS One 7:e42325, 2012.  PMC3410919.

Hurko O, Black SE, Doody R, Doraiswamy PM, Gamst A, Kaye J, Obisesan TO, Rusinek H, Scharre D, Sperling R, Weiner MW, Green RC. The ADNI Publication Policy: commensurate recognition of critical contributors who are not authors. Neuroimage 59:4196-4200, 2012.

Irizarry MC, Jin S, He F, Emond JA, Raman R, Thomas RG, Sano M, Quinn JF, Tariot PN, Galasko DR, Ishihara LS, Weil JG, Aisen PS. Incidence of new-onset seizures in mild to moderate Alzheimer disease. Archives of Neurology 69:368-372, 2012.

Johnstone D, Milward EA, Berretta R, Moscato P. Multivariate protein signatures of pre-clinical Alzheimer's disease in the Alzheimer's disease neuroimaging initiative (ADNI) plasma proteome dataset. PLoS One 7:e34341, 2012.  PMC3317783.

Jun G, Vardarajan BN, Buros J, Yu CE, Hawk MV, Dombroski BA, Crane PK, Larson EB, Mayeux R, Haines JL, Lunetta KL, Pericak-Vance MA, Schellenberg GD, Farrer LA. Comprehensive search for Alzheimer disease susceptibility loci in the APOE region. Archives of Neurology 69:1270-1279, 2012.  PMC3579659.

Katsumata Y, Todoriki H, Higashiuesato Y, Yasura S, Ohya Y, Wilcox D, Dodge H. Very old adults with better memory function have higher low-density lipoprotein cholesterol levels and lower triglyceride to high-density lipoprotein cholesterol ratios: KOCOA project. Journal of Alzheimer's Disease, Forthcoming, 2012.  NIHMS# 442202.

Katsumata Y, Todoriki H, Higashiuesato Y, Yasura S, Willcox D, Ohya Y, Willcox B, Dodge H. Metabolic Syndrome and Cognitive Decline among the Oldest-Old in Okinawa: in Search of a Mechanism. The KOCOA Project. The Journal of Gerontology: Biological Sciences 67:126-134, 2012.  PMC3261441.

Klein EP, Kaye J. Dementia Specialists and Early Adoption of Amyloid Imaging. Journal of Alzheimer's Disease, 2012.  Not funded by the NIH.

Koikkalainen J, Polonen H, Mattila J, van Gils M, Soininen H, Lotjonen J. Improved classification of Alzheimer's disease data via removal of nuisance variability. PLoS One 7:e31112, 2012.  PMC3278425.

Martin ZS, Neugebauer V, Dineley KT, Kayed R, Zhang W, Reese LC, Taglialatela G. alpha-Synuclein oligomers oppose long-term potentiation and impair memory through a calcineurin-dependent mechanism: relevance to human synucleopathic diseases. J Neurochem 120:440-452, 2012.  PMC3253169.

Mata IF, Checkoway H, Hutter CM, Samii A, Roberts JW, Kim HM, Agarwal P, Alvarez V, Ribacoba R, Pastor P, Lorenzo-Betancor O, Infante J, Sierra M, Gomez-Garre P, Mir P, Ritz B, Rhodes SL, Colcher A, Van Deerlin V, Chung KA, Quinn JF, Yearout D, Martinez E, Farin FM, Wan JY, Edwards KL, Zabetian CP. Common variation in the LRRK2 gene is a risk factor for Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society, 2012.

Mattila J, Koikkalainen J, Virkki A, van Gils M, Lotjonen J. Design and application of a generic clinical decision support system for multiscale data. IEEE Transactions on Biomedical Engineering 59:234-240, 2012.

Meyer DJ, Messer J, Singh T, Thomas PJ, Woyczynski WA, Kaye J, Lerner AJ. Random local temporal structure of category fluency responses. J Comput Neurosci 32:213-231, 2012.

Nelson PT, Alafuzoff I, Bigio EH, Bouras C, Braak H, Cairns NJ, Castellani RJ, Crain BJ, Davies P, Del Tredici K, Duyckaerts C, Frosch MP, Haroutunian V, Hof PR, Hulette CM, Hyman BT, Iwatsubo T, Jellinger KA, Jicha GA, Kovari E, Kukull WA, Leverenz JB, Love S, Mackenzie IR, Mann DM, Masliah E, McKee AC, Montine TJ, Morris JC, Schneider JA, Sonnen JA, Thal DR, Trojanowski JQ, Troncoso JC, Wisniewski T, Woltjer RL, Beach TG. Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature. Journal of Neuropathology and Experimental Neurology 71:362-381, 2012.

Petersen J, Larimer N, Kaye J, Pavel M, Hayes T. SVM to detect the presence of visitors in a smart home environment Engineering in Medicine and Biology Society:5850-5853, 2012.

Peterson A, Mattek N, Clemons A, Bowman G, Buracchio T, Kaye J, Quinn J. Serum vitamin D concentrations are associationed with falling and cognitive function in older adults. The Journal of Nutrition, Health & Aging 16:898-901, 2012.  PMC3593063.

Rasmussen JM, Lakatos A, van Erp TG, Kruggel F, Keator DB, Fallon JT, Macciardi F, Potkin SG. Empirical derivation of the reference region for computing diagnostic sensitive (1)(8)fluorodeoxyglucose ratios in Alzheimer's disease based on the ADNI sample. Biochim Biophys Acta 1822:457-466, 2012. 

Reitz C, Tosto G, Vardarajan B, Rogaeva E, Robert R, Christopher C, Haines J, Pericak-Vance M, Fallin M, Foroud T, Farrer L, Schellenberg G, St. George-Hyslop P, Mayeux R, Consortium AsDG. Independent and epistatic effects of variants in VPS10 sortilin receptors on Alzheimer’s disease risk and processing of the amyloid precursor protein (APP). Annal of Neurology, Forthcoming, 2012.

Rodgers MM, Cohen ZA, Joseph L, Rossi W. Workshop on personal motion technologies for healthy independent living: executive summary. Archives of Physical Medicine and Rehabilitation 93:935-939, 2012.

Seelye AM, Wild KV, Larimer N, Maxwell S, Kearns P, Kaye JA. Reactions to a remote-controlled video-communication robot in seniors' homes: a pilot study of feasibility and acceptance. Telemed J E Health 18:755-759, 2012.  PMC3523242.

Silbert LC, Dodge HH, Perkins LG, Sherbakov L, Lahna D, Erten-Lyons D, Woltjer R, Shinto L, Kaye JA. Trajectory of white matter hyperintensity burden preceding mild cognitive impairment. Neurology 79:741-747, 2012.  PMC3421153.

Silver M, Montana G. Fast identification of biological pathways associated with a quantitative trait using group lasso with overlaps. Stat Appl Genet Mol Biol 11:Article 7, 2012.  PMC3491888.

Soumyanath A, Zhong YP, Henson E, Wadsworth T, Bishop J, Gold BG, Quinn JF. Centella asiatica Extract Improves Behavioral Deficits in a Mouse Model of Alzheimer's Disease: Investigation of a Possible Mechanism of Action. International Journal of Alzheimer's Disease 2012:9 pages, 2012.  PMC3296229.

Stark A, Shafran I, Kaye J. Hello, Who is Calling?:  Can Words Reveal the Social Nature of Conversations? . In: Proceedings of the 2012 Conference of the North American Chapter of the Association for Computational Linguistics: Human Language Technologies; Montreal, Canada: The Association for Computational Linguistics, Forthcoming, 2012: 112-119.

Stricker NH, Dodge HH, Dowling NM, Han SD, Erosheva EA, Jagust WJ. CSF biomarker associations with change in hippocampal volume and precuneus thickness: implications for the Alzheimer's pathological cascade. Brain Imaging Behav, 2012.  PMC Journal in Process.
Tractenberg RE, Yumoto F, Aisen PS, Kaye JA, Mislevy RJ. Using the Guttman Scale to Define and Estimate Measurement Error in Items over Time: The Case of Cognitive Decline and the Meaning of "Points Lost". PLoS One 7:e30019, 2012.  PMC3281811.

Tsuang D, Leverenz JB, Lopez OL, Hamilton RL, Bennett DA, Schneider JA, Buchman AS, Larson EB, Crane PK, Kaye JA, Kramer P, Woltjer R, Kukull W, Nelson PT, Jicha GA, Neltner JH, Galasko D, Masliah E, Trojanowski JQ, Schellenberg GD, Yearout D, Huston H, Fritts-Penniman A, Mata IF, Wan JY, Edwards KL, Montine TJ, Zabetian CP. GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology. Neurology 79:1944-1950, 2012.  PMC3484986.

Wild K, Mattek N, Maxwell S, Dodge H, Jimison H, Kaye J. Computer related self-efficacy and anxiety in older adults with and without mild cognitive impairment. Alzheimer’s & Dementia 8:544-552, 2012.  PMC3483565

Yuan L, Wang Y, Thompson PM, Narayan VA, Ye J. Multi-source feature learning for joint analysis of incomplete multiple heterogeneous neuroimaging data. Neuroimage 61:622-632, 2012.  PMC3358419.

Zou F, Chai HS, Younkin CS, Allen M, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, Lincoln S, Bisceglio G, Georgescu C, Kouri N, Kolbert CP, Jen J, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Petersen RC, Graff-Radford NR, Dickson DW, Younkin SG, Ertekin-Taner N. Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants. PLoS Genet 8:e1002707, 2012.  PMC3369937.

2011

Anderson V, Lenar D, Quinn J, Rooney W. The blood -brain barrier adn microvascular water exchange in Alzheimer's disease. Cardiovascular Psychiatry and Neurology, 2011: 615829, 2011. PMC3114411

Anekonda T, Wadsworth T, Frahler K, Harris C, Petriko B, Ralle M, Woltjer R, Quinn J. Phytic acid as a potential treatment for Alzheimer's pathology:  Evidence from animal and in vitro models. Journal of Alzheimer's Disease 23:21-35, 2011.  PMC3021000.

Austin D, Hayes TL, Kaye J, Mattek N, Pavel M. On the Disambiguation of Passively Measured In-home Gait Velocities from Multi-person Smart Homes. J Ambient Intell Smart Environ 3:165-174, 2011.  PMC3093199

Austin D, Jimison H, Hayes T, Mattek N, Kaye J, Pavel M. Measuring motor speed through typing: a surrogate for the finger tapping test. Behav Res Methods, 43(4):903-909, 2011.  PMC3151309

Bowman GL, Shannon J, Ho E, Traber MG, Frei B, Oken BS, Kaye JA, Quinn JF. Reliability and Validity of Food Frequency Questionnaire and Nutrient Biomarkers in Elders With and Without Mild Cognitive Impairment. Alzheimer Disease and Associated Disorders 25:49-57, 2011.  PMC3042482.

Britschgi M, Rufibach K, Bauer S, Clar C, Kaye J, Li G, Peskind E, Quinn J, Galasko D, Wyss-Coray T. Modeling of pathological traits in Alzheimer's disease based on systemic extracellular signaling proteome. Molecular & Cellular Proteomics, Forthcoming, 2011. PMC3205866

Chen-Plotkin AS, Martinez-Lage M, Sleiman PM, Hu W, Greene R, Wood EM, Bing S, Grossman M, Schellenberg GD, Hatanpaa KJ, Weiner MF, White CL, 3rd, Brooks WS, Halliday GM, Kril JJ, Gearing M, Beach TG, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF, Pickering-Brown SM, Snowden J, van Swieten JC, Heutink P, Seelaar H, Murrell JR, Ghetti B, Spina S, Grafman J, Kaye JA, Woltjer RL, Mesulam M, Bigio E, Llado A, Miller BL, Alzualde A, Moreno F, Rohrer JD, Mackenzie IR, Feldman HH, Hamilton RL, Cruts M, Engelborghs S, De Deyn PP, Van Broeckhoven C, Bird TD, Cairns NJ, Goate A, Frosch MP, Riederer PF, Bogdanovic N, Lee VM, Trojanowski JQ, Van Deerlin VM. Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration. Archives of Neurology 68:488-497, 2011.  PMC3160280

Chiang GC, Insel PS, Tosun D, Schuff N, Truran-Sacrey D, Raptentsetsang S, Jack CR, Jr., Weiner MW. Identifying cognitively healthy elderly individuals with subsequent memory decline by using automated MR temporoparietal volumes. Radiology 259:844-851, 2011.  PMC3099048.

Copenhaver PF, Anekonda TS, Musashe D, Robinson KM, Ramaker JM, Swanson TL, Wadsworth TL, Kretzschmar D, Woltjer RL, Quinn JF. A translational continuum of model systems for evaluating treatment strategies in Alzheimer's disease: isradipine as a candidate drug. Dis Model Mech, 2011.  PMC3180227

Dodge H, Chang C, Kamboh I, Ganguli M. Risk of Alzheimer’s Disease Incidence Attributable to Vascular Disease in the Population.  . Alzheimer’s & Dementia 7:356-360, 2011.  PMC21575878.

Elias-Sonnenschein LS, Viechtbauer W, Ramakers IH, Verhey FR, Visser PJ. Predictive value of APOE-{varepsilon}4 allele for progression from MCI to AD-type dementia: a meta-analysis. Journal of Neurology, Neurosurgery, and Psychiatry, 2011.  PMC Journal in Process.

Erten-Lyons D, Wilmot B, Anur P, McWeeney S, Westaway S, Silbert L, Kramer P, Kaye J. Microcephaly Genes and Risk of Late-onset Alzheimer Disease. Alzheimer Disease and Associated Disorders, 25(3): 276-282, 2011.  PMC3136560

Evans DA, Grodstein F, Loewenstein D, Kaye J, Weintraub S. Reducing case ascertainment costs in U.S. population studies of Alzheimer's disease, dementia, and cognitive impairment-Part 2. Alzheimers Dement 7:110-123, 2011.  PMC3033654.

Fonareva I, Amen A, Zajdel D, Ellingson R, Oken B. Assessing sleep architecture in demential caregivers at home using an ambulatory polysomnographic system. Journal of Geriatric Psychiatry and Neurology 24:50-59, 2011.  NIHMSID#371227

Fried-Oken M, Rowland C, Oken B. Evidence to support augmentative communication treatment for primary progressive aphasia. In: Neurology, 2011: A76.

Howieson D, Mattek N, Seelye A, Dodge H, Wasserman D, Zitzelberger T, Kaye J. Serial Position Effects in Mild Cognitive Impairment. Journal of Clinical and Experimental Neuropsychology 2:1-8, 2011.  PMC3058855.
Hurko O, Black S, Doody R, Doraiswamy P, Gamst A, Kaye J, Obisesan T, Rusinek H, Scharre D, Sperling R, Weiner M, Green R. The ADNI Publication Policy:  Commensurate recognition of critical contributors who are not authors. Neuroimage, Forthcoming, 2011.  PMC Journal in Process.

Katsumata Y, Todoriki H, Higashiuesato Y, Yasura S, Willcox D, Ohya Y, Willcox B, Dodge H. Metabolic Syndrome and Cognitive Decline among the Oldest-Old in Okinawa: in Search of a Mechanism. The KOCOA Project. The Journal of Gerontology: Biological Sciences, 67(2): 126-134, 2011.  PMC3261441

Kaye, J, Mattek N, Dodge H, Buracchio T, Austin D, Hagler S, Pavel M, Hayes T. One Walk a Year to 1000 Within a Year: Continuous In-home Unobtrusive Gait Assessment of Older Adults. Gait and Posture, 35(2): 197-202, 2011. PMC3278504
 
Kaye J, Maxwell S, Mattek N, Hayes T, Dodge H, Pavel M, Jimison H, Wild K, Boise L, Zitzelberger T. Intelligent systems for assessing aging changes: Home-based, unobtrusive, and continuous assessment of aging. Journal of Gerontology:  Psychological Sciences, 66 Suppl 1, i180-i190, 2011.  PMC3132763

Kim S, Swaminathan S, Shen L, Risacher SL, Nho K, Foroud T, Shaw LM, Trojanowski JQ, Potkin SG, Huentelman MJ, Craig DW, DeChairo BM, Aisen PS, Petersen RC, Weiner MW, Saykin AJ. Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort. Neurology 76:69-79, 2011.  PMC2964649

Lu Z, Leen TK, Kaye J. Kernels for longitudinal data with variable sequence length and sampling intervals. Neural Comput 23:2390-2420, 2011.  PMC Journal in Process

Montine TJ, Peskind ER, Quinn JF, Wilson AM, Montine KS, Galasko D. Increased Cerebrospinal Fluid F(2)-Isoprostanes are Associated with Aging and Latent Alzheimer's Disease as Identified by Biomarkers. Neuromolecular Medicine 13:37-42, 2011.  PMC3000441

Naj A, Jun  G, G B, L W, Vardarajan B, Buros J, Gallins P, Buxbaum  J, Jarvik G, Crane P, Larson E, Bird T, Boeve B, Graff-Radford N, De Jager P, Evans D, Schneider J, Carrasquillo M, Ertekin-Taner N, Younkin S, Cruchaga C, Kauwe J, Nowotny P, Kramer P, Hardy J, Huentelman M, Myers A B, M , Demirci F, Baldwin C, Green R, Rogaeva E, P G-H, Consortium ADG. Common variants in MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nature Genetics, 2011.  PMC3090745

Oken B, Amen A. Electroencephalography and Evoked Potentials in Geriatrics. In: Knoefe lJ, Albert M, eds. Clinical Neurology of Aging: Oxford University Press; 113-127, 2011.

Oken B, Fonareva I, Wahbeh H. Stress-related cognitive dysfunction in dementia caregivers. In: Neurology, 2011: A511.

Oken B, Fonareva I, Wahbeh H. Stress-related cognitive dysfunction in dementia caregivers. Journal of Geriatric Psychiatry and Neurology, 24(4): 191-198,  2011. NIHMSID#370251

Perrin R, Craig-Schapiro R, Malone J, Shah A, Gilmore P, David A, Roe C, Peskind E, Li G, Galasko D, Clark C, Quinn J, Kaye J, Morris J, Holtzman D, Townsend R, Fagan A. Identification and Validation of Novel Cerebrospinal Fluid Biomarkers for Staging Early Alzheimer's Disease. PLoS ONE 6:e16032, 2011.  PMC3020224

Roark B, Mitchell M, Hosom J, Hollingshead K, Kaye J. Spoken language derived measures for detecting mild cognitive impairment. Transactions on Audio, Speech and Language Processing, 19(7):2081-2090, 2011.  PMC3244269

Shulman JM, Chipendo P, Chibnik LB, Aubin C, Tran D, Keenan BT, Kramer PL, Schneider JA, Bennett DA, Feany MB, De Jager PL. Functional Screening of Alzheimer Pathology Genome-wide Association Signals in Drosophila. The American Journal of Human Genetics 88:232-238, 2011.  PMC3035702

Snyder PJ, Jackson CE, Petersen RC, Khachaturian AS, Kaye J, Albert MS, Weintraub S. Assessment of cognition in mild cognitive impairment: A comparative study. Alzheimers Dement 7:338-355, 2011.  PMC Journal in Process.

Sonnen J, Santa Cruz K, Hemmy L, Woltjer R, Leverenz J, Montine K, Jack C, Kaye J, Lim K, Larson E, White L, Montine T. Ecology of aging human brain. Archives of Neurology 68:1049-1056, 2011.  PMC3218566

Sperling RA, Aisen PS, Beckett LA, Bennett DA, Craft S, Fagan AM, Iwatsubo T, Jack CR, Kaye J, Montine TJ, Park DC, Reiman EM, Rowe CC, Siemers E, Stern Y, Yaffe K, Carrillo MC, Thies B, Morrison-Bogorad M, Wagster MV, Phelps CH. Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging and the Alzheimer's Association workgroup. Alzheimers Dement, 2011. PMC3220946

Tosun D, Schuff N, Mathis C, Jagust W, Weiner M, Alzheimer's Disease Neuroimaging Initiative . Spatial patterns of brain amyloid-beta burden and atrophy rate associations in mild cognitive impairment.  Brain 134:1077-1088, 2011.  PMC3069703

Villeda SA, Luo J, Mosher KI, Zou B, Britschgi M, Bieri G, Stan TM, Fainberg N, Ding Z, Eggel A, Lucin KM, Czirr E, Park JS, Couillard-Despres S, Aigner L, Li G, Peskind ER, Kaye JA, Quinn JF, Galasko DR, Xie XS, Rando TA, Wyss-Coray T. The ageing systemic milieu negatively regulates neurogenesis and cognitive function. Nature 477:90-94, 2011. PMC3170097
 
Wang Y, Hancock AM, Bradner J, Chung KA, Quinn JF, Peskind ER, Galasko D, Jankovic J, Zabetian CP, Kim HM, Leverenz JB, Montine TJ, Ginghina C, Edwards KL, Snapinn KW, Goldstein DS, Shi M, Zhang J. Complement 3 and factor h in human cerebrospinal fluid in Parkinson's disease, Alzheimer's disease, and multiple-system atrophy. The American Journal of Pathology 178:1509-1516, 2011.  PMC Journal in Process.  PMC3078443

Katsumata Y, Todoriki H, Yasura S, Dodge H. Timed Up & Go Test Predicts Cognitive Decline among Healthy Elderly Aged 80 and Older in Okinawa: KOCOA project. Journal of American Geriatrics Society,59(11): 2188-2189, 2011. PMC3291095

2010

Austin D, Leen T, Hayes TL, Kaye J, Jimison H, Mattek N, Pavel M. Model-based inference of cognitive processes from unobtrusive gait velocity measurements. Conference Proceedings : Engineering in Medicine and Biology Society 1:5230-5233, 2010.

Boise L, Eckstrom E, Fagnan L, King A, Goubaud M, Buckley DI, Morris C. The rural older adult memory (ROAM) study: A practice-based intervention to improve dementia screening and diagnosis. Journal of the American Board of Family Medicine 23:486-498, 2010.  PMC Journal in Progress.

Bowman GL, Shannon J, Frei B, Kaye JA, Quinn JF. Uric acid as a CNS antioxidant. Journal of Alzheimer's Disease 19:1331-1336, 2010.  PMC2859185.

Bowman GL, Shannon J, Ho E, Traber MG, Frei B, Oken BS, Kaye JA, Quinn JF. Reliability and Validity of Food Frequency Questionnaire and Nutrient Biomarkers in Elders With and Without Mild Cognitive Impairment. Alzheimer Disease and Associated Disorders, 2010. PMC3042482

Buracchio T, Arvanitakis Z, Leurgans S, Bennett DA. Parkinsonian signs and incident falls in older persons without Parkinson's disease. In: Journal of the American Geriatrics Society. 2010/02/04 ed, 2010: 205-206.

Buracchio T, Dodge H, Howieson D, Wasserman D, Kaye J. The trajectory of gait speed preceding mild cognitive impairment. Archives of Neurology 67:980-986, 2010.  PMC2921227.

Chaves ML, Camozzato AL, Kohler C, Kaye J. Predictors of the progression of dementia severity in brazilian patients with Alzheimer's disease and vascular dementia. Int J Alzheimer Dis 2010, 2010.  PMC2925083.

Craig-Schapiro R, Perrin RJ, Roe CM, Xiong C, Carter D, Cairns NJ, Mintun MA, Peskind ER, Li G, Galasko DR, Clark CM, Quinn JF, D'Angelo G, Malone JP, Townsend RR, Morris JC, Fagan AM, Holtzman DM. YKL-40: a novel prognostic fluid biomarker for preclinical Alzheimer's disease. Biol Psychiatry 68:903-912, 2010.  PMC3011944.

Dodge HH, Katsumata Y, Todoriki H, Yasura S, Willcox DC, Bowman GL, Willcox B, Leonard S, Clemons A, Oken BS, Kaye JA, Traber MG. Comparisons of Plasma/Serum Micronutrients Between Okinawan and Oregonian Elders: A Pilot Study. J Gerontol A Biol Sci Med Sci, 2010.  PMC3031451

Hare J. Trafficking of amyloid beta-precursor protein products C83 and C99 on the endocytic pathway. Biochem Biophys Res Commun 401:219-224, 2010.  PMC Journal In Process.

Hayes TL, Riley T, Pavel M, Kaye JA. Estimation of rest-activity patterns using motion sensors. Conference Proceedings : Engineering in Medicine and Biology Society 1:2147-2150, 2010. PMC3057896

Ho AJ, Stein JL, Hua X, Lee S, Hibar DP, Leow AD, Dinov ID, Toga AW, Saykin AJ, Shen L, Foroud T, Pankratz N, Huentelman MJ, Craig DW, Gerber JD, Allen AN, Corneveaux JJ, Stephan DA, DeCarli CS, DeChairo BM, Potkin SG, Jack CR, Jr., Weiner MW, Raji CA, Lopez OL, Becker JT, Carmichael OT, Thompson PM. A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly. Proc Natl Acad Sci U S A 107:8404-8409, 2010.  PMC2889537.

Hong Z, Shi M, Chung KA, Quinn JF, Peskind ER, Galasko D, Jankovic J, Zabetian CP, Leverenz JB, Baird G, Montine TJ, Hancock AM, Hwang H, Pan C, Bradner J, Kang UJ, Jensen PH, Zhang J. DJ-1 and alpha-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease. Brain 133:713-726, 2010.  PMC2842513.

Jun G, Naj AC, Beecham GW, Wang LS, Buros J, Gallins PJ, Buxbaum JD, Ertekin-Taner N, Fallin MD, Friedland R, Inzelberg R, Kramer P, Rogaeva E, St George-Hyslop P, Arnold SE, Baldwin CT, Barber R, Beach T, Bigio EH, Bird TD, Boxer A, Burke JR, Cairns N, Carroll SL, Chui HC, Clark DG, Cotman CW, Cummings JL, Decarli C, Diaz-Arrastia R, Dick M, Dickson DW, Ellis WG, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Gearing M, Geschwind DH, Ghetti B, Gilman S, Giordani B, Glass J, Graff-Radford NR, Green RC, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Johnson N, Karlawish J, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Lah JJ, Levey AI, Lieberman A, Lopez OL, Mack WJ, Markesbery W, Marson DC, Martiniuk F, Masliah E, McKee AC, Mesulam M, Miller JW, Miller BL, Miller CA, Parisi JE, Perl DP, Peskind E, Petersen RC, Poon W, Quinn JF, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosenberg RN, Sano M, Schneider JA, Schneider LS, Seeley W, Shelanski ML, Smith CD, Spina S, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Woltjer RL, Younkin SG, Cantwell LB, Dombroski BA, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Lunetta KL, Martin ER, Montine TJ, Goate AM, Blacker D, Tsuang DW, Beekly D, Cupples LA, Hakonarson H, Kukull W, Foroud TM, Haines J, Mayeux R, Farrer LA, Pericak-Vance MA, Schellenberg GD. Meta-analysis Confirms CR1, CLU, and PICALM as Alzheimer Disease Risk Loci and Reveals Interactions With APOE Genotypes. Archives of Neurology, 67(12): 1473-1484, 2010. PMC3048805

Kramer PL, Xu H, Woltjer RL, Westaway SK, Clark D, Erten-Lyons D, Kaye JA, Welsh-Bohmer KA, Troncoso JC, Markesbery WR, Petersen RC, Turner RS, Kukull WA, Bennett DA, Galasko D, Morris JC, Ott J. Alzheimer disease pathology in cognitively healthy elderly: A genome-wide study. Neurobiology of Aging, 32(12): 2113-2122, 2010. PMC2990809.

Kruer MC, Koch TK, Bourdette DN, Chabas D, Waubant E, Mueller S, Moscarello MA, Dalmau J, Woltjer RL, Adamus G. Nmda receptor encephalitis mimicking seronegative neuromyelitis optica. Neurology 74:1473-1475, 2010.  PMC2872802.

Montine TJ, Peskind ER, Quinn JF, Wilson AM, Montine KS, Galasko D. Increased Cerebrospinal Fluid F(2)-Isoprostanes are Associated with Aging and Latent Alzheimer's Disease as Identified by Biomarkers. Neuromolecular Medicine [Epub ahead of print, 2010.  NIHMS203909.

Montine TJ, Shi M, Quinn JF, Peskind ER, Craft S, Ginghina C, Chung KA, Kim H, Galasko DR, Jankovic J, Zabetian CP, Leverenz JB, Zhang J. CSF Abeta(42) and tau in Parkinson's disease with cognitive impairment. Movement Disorders : Official Journal of the Movement Disorder Society, 25(15): 2682-2685, 2010.  PMC2978754

Quinn JF, Harris CJ, Cobb KE, Domes C, Ralle M, Brewer G, Wadsworth TL. A Copper-Lowering Strategy Attenuates Amyloid Pathology in a Transgenic Mouse Model of Alzheimer's Disease. Journal of Alzheimer's Disease, 2010.  PMC2931577.

Quinn JF, Raman R, Thomas RG, Yurko-Mauro K, Nelson EB, Van Dyck C, Galvin JE, Emond J, Jack CR, Jr., Weiner M, Shinto L, Aisen PS. Docosahexaenoic acid supplementation and cognitive decline in Alzheimer disease: a randomized trial. JAMA: The Journal of the American Medical Association 304:1903-1911, 2010.  PMC3259852

Shi M, Zabetian CP, Hancock AM, Ginghina C, Hong Z, Yearout D, Chung KA, Quinn JF, Peskind ER, Galasko D, Jankovic J, Leverenz JB, Zhang J. Significance and confounders of peripheral DJ-1 and alpha-synuclein in Parkinson disease. Neurosci Lett,480(1): 78-82, 2010. PMC2943649

Silbert LC, Kaye J. Neuroimaging and cognition in Parkinson's disease dementia. Brain Pathology 20:646-653, 2010.  NIHMS# 165062.

Sonnen JA, Montine KS, Quinn JF, Breitner JC, Montine TJ. Cerebrospinal Fluid Biomarkers in Mild Cognitive Impairment and Dementia. Journal of Alzheimer's Disease 19:301-309, 2010.  PMC2891184.

Subramanian S, Ayala P, Wadsworth TL, Harris CJ, Vandenbark AA, Quinn JF, Offner H. CCR6: A Biomarker for Alzheimer's-like Disease in a Triple Transgenic Mouse Model. Journal of Alzheimer's Disease, 22(2): 619-629, 2010. PMC2988888

Takechi H, Dodge HH. Scenery Picture Memory Test: a new type of quick and effective screening test to detect early stage Alzheimer's disease patients. Geriatr Gerontol Int 10:183-190, 2010.  PMC2892033.

Van Deerlin VM, Sleiman PM, Martinez-Lage M, Chen-Plotkin A, Wang LS, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF, Grossman M, Arnold SE, Mann DM, Pickering-Brown SM, Seelaar H, Heutink P, van Swieten JC, Murrell JR, Ghetti B, Spina S, Grafman J, Hodges J, Spillantini MG, Gilman S, Lieberman AP, Kaye JA, Woltjer RL, Bigio EH, Mesulam M, Al-Sarraj S, Troakes C, Rosenberg RN, White CL, 3rd, Ferrer I, Llado A, Neumann M, Kretzschmar HA, Hulette CM, Welsh-Bohmer KA, Miller BL, Alzualde A, de Munain AL, McKee AC, Gearing M, Levey AI, Lah JJ, Hardy J, Rohrer JD, Lashley T, Mackenzie IR, Feldman HH, Hamilton RL, Dekosky ST, van der Zee J, Kumar-Singh S, Van Broeckhoven C, Mayeux R, Vonsattel JP, Troncoso JC, Kril JJ, Kwok JB, Halliday GM, Bird TD, Ince PG, Shaw PJ, Cairns NJ, Morris JC, McLean CA, Decarli C, Ellis WG, Freeman SH, Frosch MP, Growdon JH, Perl DP, Sano M, Bennett DA, Schneider JA, Beach TG, Reiman EM, Woodruff BK, Cummings J, Vinters HV, Miller CA, Chui HC, Alafuzoff I, Hartikainen P, Seilhean D, Galasko D, Masliah E, Cotman CW, Tunon MT, Martinez MC, Munoz DG, Carroll SL, Marson D, Riederer PF, Bogdanovic N, Schellenberg GD, Hakonarson H, Trojanowski JQ, Lee VM. Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nature Genetics 43:234-239, 2010.  PMC2828525.

Wolk DA, Dickerson BC, Weiner M, Aiello M, Aisen P, Albert MS, Alexander G, Anderson HS, Anderson K, Apostolova L, Arnold S, Ashford W, Assaly M, Asthana S, Bandy D, Bartha R, Bates V, Beckett L, Bell KL, Benincasa AL, Bergman H, Bernick C, Bernstein M, Black S, Blank K, Borrie M, Brand C, Brewer J, Brown AD, Burns JM, Cairns NJ, Caldwell C, Capote H, Carlsson CM, Carmichael O, Cellar JS, Celmins D, Chen K, Chertkow H, Chowdhury M, Clark D, Connor D, Correia S, Crawford K, Dale A, de Leon MJ, De Santi SM, Decarli C, Detoledo-Morrell L, Devous M, Diaz-Arrastia R, Dolen S, Donohue M, Doody RS, Doraiswamy PM, Duara R, Englert J, Farlow M, Feldman H, Felmlee J, Fleisher A, Fletcher E, Foroud TM, Foster N, Fox N, Frank R, Gamst A, Given CA, 2nd, Graff-Radford NR, Green RC, Griffith R, Grossman H, Hake AM, Hardy P, Harvey D, Heidebrink JL, Hendin BA, Herring S, Honig LS, Hosein C, Robin Hsiung GY, Hudson L, Ismail MS, Jack CR, Jr., Jacobson S, Jagust W, Jayam-Trouth A, Johnson K, Johnson H, Johnson N, Johnson KA, Johnson S, Kachaturian Z, Karlawish JH, Kataki M, Kaye J, Kertesz A, Killiany R, Kittur S, Koeppe RA, Korecka M, Kornak J, Kozauer N, Lah JJ, Laubinger MM, Lee VM, Lee TY, Lerner A, Levey AI, Longmire CF, Lopez OL, Lord JL, Lu PH, Macavoy MG, Malloy P, Marson D, Martin-Cook K, Martinez W, Marzloff G, Mathis C, Mc-Adams-Ortiz C, Mesulam M, Miller BL, Mintun MA, Mintzer J, Molchan S, Montine T, Morris J, Mulnard RA, Munic D, Nair A, Neu S, Nguyen D, Norbash A, Oakley M, Obisesan TO, Ogrocki P, Ott BR, Parfitt F, Pawluczyk S, Pearlson G, Petersen R, Petrella JR, Potkin S, Potter WZ, Preda A, Quinn J, Rainka M, Reeder S, Reiman EM, Rentz DM, Reynolds B, Richard J, Roberts P, Rogers J, Rosen A, Rosen HJ, Rusinek H, Sabbagh M, Sadowsky C, Salloway S, Santulli RB, Saykin AJ, Scharre DW, Schneider L, Schneider S, Schuff N, Shah RC, Shaw L, Shen L, Silverman DH, Simpson DM, Sink KM, Smith CD, Snyder PJ, Spann BM, Sperling RA, Spicer K, Stefanovic B, Stern Y, Stopa E, Tang C, Tariot P, Taylor-Reinwald L, Thai G, Thomas RG, Thompson P, Tinklenberg J, Toga AW, Tremont G, Trojanowki JQ, Trost D, Turner RS, van Dyck CH, Vanderswag H, Varon D, Villanueva-Meyer J, Villena T, Walter S, Wang P, Watkins F, Williamson JD, Wolk D, Wu CK, Zerrate M, Zimmerman EA. Apolipoprotein E (APOE) genotype has dissociable effects on memory and attentional-executive network function in Alzheimer's disease. Proc Natl Acad Sci U S A, 2010.  PMC2890481.

Woltjer R, Duerson K, Fullmer F, Mookherjee P, Ryan A, Montine T, Kaye J, Quinn J, Silbert L, Erten-Lyons D, Leverenz J, Bird T, Pow D, Watson G, Cook D. Aberrant Detergent-insoluble EAAT2 accumulates in Alzheimer's disease. Journal of Neuropathology and Experimental Neurology 69:667-676, 2010.  PMC3097122

Yu C, Bird T, Bekris L, Montine T, Leverenz J, Steinbart E, Galloway N, Feldman H, Woltjer R, Miller C, McCarthy Wood E, Grossman M, McCluskey L, Clark C, Neumann M, Danek A, Galasko D, Arnold S, Chen-Plotkin A, Karydas A, Miller B, Trojanowski J, Lee V, Schellenberg G, Van Deerlin V. The spectrum of mutations in progranulin:  A collaborative study screening 545 cases of neurodegeneration. Archives of Neurology 67:161-170, 2010.  PMC2901991.

2009

Bowman G, Dodge H, Calabrese C, Oken B, Frei B, Kaye J, Quinn J. Ascorbic acid and rates of cognitive decline in Alzheimer's disease. The Journal of Alzheimer's Disease 16:93-98, 2009.  PMC2674290.

Britschgi M, Olin CE, Johns HT, Takeda-Uchimura Y, LeMieux MC, Rufibach K, Rajadas J, Zhang H, Tomooka B, Robinson WH, Clark CM, Fagan AM, Galasko DR, Holtzman DM, Jutel M, Kaye JA, Lemere CA, Leszek J, Li G, Peskind ER, Quinn JF, Yesavage JA, Ghiso JA, Wyss-Coray T. Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease. Proc Natl Acad Sci U S A 106:12145-12150, 2009.  PMC2715538.

Calvert JF, Jr., Kaye J, Leahy M, Hexem K, Carlson N. Technology use by rural and urban oldest old. Technol Health Care 17:1-11, 2009.  PMC2830255.

Carmine-Simmen K, Proctor T, Tschape J, Poeck B, Triphan T, Strauss R, Kretzschmar D. Neurotoxic effects induced by the Drosophila amyloid-beta peptide suggest a conserved toxic function. Neurobiol Dis 33:274-281, 2009. 

Chaves ML, Camozzato AL, Eizirik CL, Kaye J. Predictors of Normal and Successful Aging Among Urban-Dwelling Elderly Brazilians. The Journals of Gerontology Series B: Psychological Sciences and Social Sciences 64:597-602, 2009.  PMC2800815.

Chaves ML, Camozzato AL, Godinho C, Piazenski I, Kaye J. Incidence of Mild Cognitive Impairment and Alzheimer Disease in Southern Brazil. Journal of Geriatric Psychiatry and Neurology 22:181-187, 2009.  PMC Journal in Process.

Dodge H. The early detection of cognitive impairment:  Two approaches to assess longitudinal trajectories. In: National Alzheimer's Coordinating Center (NACC). Baltimore, MD, 2009.

Dodge H, Katsumata Y, Todoriki H, Willcox D, Leahy M, Michael Y, Kaye J. Social interaction as a potential key to optimal cognitive aging:  Okinawa-Oregon comparative study of sucessful aging. In: The Gerontological Society of America. Atlanta, GA, 2009.

Dodge H, Traber M, Leonard S, Katsumata Y, Todoriki H, Bowman G, Suzuki M, Willcox D, Yasura S, Oken B, Kaye J. Circulating micronutrients in Okinawan and Oregonian elderly. In: Linus Pauling Diet and Optinal Aging Annual Meeting; Portland, Oregon  2009.

Dodge HH, Meguro K, Ishii H, Yamaguchi S, Saxton JA, Ganguli M. Cross-cultural comparisons of the Mini-mental State Examination between Japanese and U.S. cohorts. Int Psychogeriatr 21:113-122, 2009. PMC2639652.

Duerson K, Woltjer RL, Mookherjee P, Leverenz JB, Montine TJ, Bird TD, Pow DV, Rauen T, Cook DG. Detergent-insoluble EAAC1/EAAT3 aberrantly accumulates in hippocampal neurons of Alzheimer's disease patients. Brain Pathology 19:267-278, 2009.  PMC2657182.

Erten-Lyons D, McWeeney S, Wilmot B, Kramer P, Kaye J. A polymorphism in ASPM and brain size. In: American Academy of Neurology: Neurology, 2009.

Erten-Lyons D, Woltjer RL, Dodge H, Nixon R, Vorobik R, Calvert JF, Leahy M, Montine T, Kaye J. Factors associated with resistance to dementia despite high Alzheimer disease pathology. Neurology 72:354-360, 2009.  PMC275065.

Hagler S, Austin D, Hayes T, Kaye J, Pavel M. Unobtrusive and Ubiquitous In-Home Monitoring: A Methodology for Continuous Assessment of Gait Velocity in Elders. IEEE Transactions on Biomedical Engineering, 2009.  PMC2846826

Hatt WJ, Vanbaak EA, Jimison HB, Hagler S, Hayes TL, Pavel M, Kaye J. The exploration & forensic analysis of computer usage data in the elderly. Conference Proceedings : Engineering in Medicine and Biology Society 2009:1216-1219, 2009.  PMC284625

Hayes T, Kaye J. Gathering the evidence:  Supporting large-sale research deployments.  . Intel Technology Journal 13:148-167, 2009. Not a peer-reviewed journal article.

Hayes TL, Cobbinah K, Dishongh T, Kaye JA, Kimel J, Labhard M, Leen T, Lundell J, Ozertem U, Pavel M, Philipose M, Rhodes K, Vurgun S. A study of medication-taking and unobtrusive, intelligent reminding. Telemed J E Health 15:770-776, 2009. Not an NIH Funded Manuscript.

Hayes TL, Hagler S, Austin D, Kaye J, Pavel M. Unobtrusive assessment of walking speed in the home using inexpensive PIR sensors. Conference Proceedings : Engineering in Medicine and Biology Society 1:7248-7251, 2009.  PMC2664300

Hayes TL, Larimer N, Adami A, Kaye JA. Medication adherence in healthy elders: small cognitive changes make a big difference. Journal of Aging Health 21:567-580, 2009.  PMC2910516

Holland D, Brewer JB, Hagler DJ, Fenema-Notestine C, Dale AM, Weiner M, Thal L, Petersen R, Jack CR, Jr., Jagust W, Trojanowki J, Toga AW, Beckett L, Green RC, Gamst A, Potter WZ, Montine T, Anders D, Bernstein M, Felmlee J, Fox N, Thompson P, Schuff N, Alexander G, Bandy D, Koeppe RA, Foster N, Reiman EM, Chen K, Shaw L, Lee VM, Korecka M, Crawford K, Neu S, Harvey D, Kornak J, Kachaturian Z, Frank R, Snyder PJ, Molchan S, Kaye J, Vorobik R, Quinn J, Schneider L, Pawluczyk S, Spann B, Fleisher AS, Vanderswag H, Heidebrink JL, Lord JL, Johnson K, Doody RS, Villanueva-Meyer J, Chowdhury M, Stern Y, Honig LS, Bell KL, Morris JC, Mintun MA, Schneider S, Marson D, Griffith R, Badger B, Grossman H, Tang C, Stern J, Detoledo-Morrell L, Shah RC, Bach J, Duara R, Isaacson R, Strauman S, Albert MS, Pedroso J, Toroney J, Rusinek H, de Leon MJ, De Santi SM, Doraiswamy PM, Petrella JR, Aiello M, Clark CM, Pham C, Nunez J, Smith CD, Given CA, 2nd, Hardy P, Dekosky ST, Oakley M, Simpson DM, Ismail MS, Porsteinsson A, McCallum C, Cramer SC, Mulnard RA, McAdams-Ortiz C, Diaz-Arrastia R, Martin-Cook K, Devous M, Levey AI, Lah JJ, Cellar JS, Burns JM, Anderson HS, Laubinger MM, Bartzokis G, Silverman DH, Lu PH, Fletcher R, Parfitt F, Johnson H, Farlow M, Herring S, Hake AM, van Dyck CH, Macavoy MG, Bifano LA, Chertkow H, Bergman H, Hosein C, Black S, Graham S, Caldwell C, Feldman H, Assaly M, Hsiung GY, Kertesz A, Rogers J, Trost D, Bernick C, Gitelman D, Johnson N, Mesulam M, Sadowsky C, Villena T, Mesner S, Aisen PS, Johnson KB, Behan KE, Sperling RA, Rentz DM, Johnson KA, Rosen A, Tinklenberg J, Ashford W, Sabbagh M, Connor D, Obradov S, Killiany R, Norbash A, Obisesan TO, Jayam-Trouth A, Wang P, Auchus AP, Huang J, Friedland RP, Decarli C, Fletcher E, Carmichael O, Kittur S, Mirje S, Johnson SC, Borrie M, Lee TY, Asthana S, Carlsson CM, Potkin SG, Highum D, Preda A, Nguyen D, Tariot PN, Hendin BA, Scharre DW, Kataki M, Beversdorf DQ, Zimmerman EA, Celmins D, Brown AD, Gandy S, Marenberg ME, Rovner BW, Pearlson G, Blank K, Anderson K, Saykin AJ, Santulli RB, Pare N, Williamson JD, Sink KM, Potter H, Ashok Raj B, Giordano A, Ott BR, Wu CK, Cohen R, Wilks KL, Safirstein BE. Subregional neuroanatomical change as a biomarker for Alzheimer's disease. Proceedings of the National Academy of Science USA 106:20954-20959, 2009.  PMC2791580.

Hosom J. Speaker-independent phoneme alignment using transition-dependent states. Speech Communication 51:352-368, 2009.  PMC2682710

Kaye J. Ginkgo biloba prevention trials:  More than an ounce of prevention learned. Archives of Neurology 66:652-654, 2009.  Not a peer-reviewed journal article.

Kaye J, Micheal Y, Calvert J, Leahy M, Crawford D, Kramer P. Exceptional brain aging in rural population-based cohort. Journal of Rural Health 25:320-325, 2009. NIHMSID#371470

Khachaturian ZS, Snyder PJ, Doody R, Aisen P, Comer M, Dwyer J, Frank RA, Holzapfel A, Khachaturian AS, Korczyn AD, Roses A, Simpkins JW, Schneider LS, Albert MS, Egge R, Deves A, Ferris S, Greenberg BD, Johnson C, Kukull WA, Poirier J, Schenk D, Thies W, Gauthier S, Gilman S, Bernick C, Cummings JL, Fillit H, Grundman M, Kaye J, Mucke L, Reisberg B, Sano M, Pickeral O, Petersen RC, Mohs RC, Carrillo M, Corey-Bloom JP, Foster NL, Jacobsen S, Lee V, Potter WZ, Sabbagh MN, Salmon D, Trojanowski JQ, Wexler N, Bain LJ. A roadmap for the prevention of dementia II: Leon Thal Symposium 2008. Alzheimers Dement 5:85-92, 2009.  PMC2544623.

Lavery L, Dodge H, Snitz B, Ganguli M. Cognitive decline and mortality in a community-based cohort: The Monongahela Valley independent elders survey Journal of the American Geriatrics Society 57:94-100, 2009.  PMC2768614

Leverenz JB, Quinn JF, Zabetian C, Zhang J, Montine KS, Montine TJ. Cognitive impairment and dementia in patients with Parkinson disease. Curr Top Med Chem 9:903-912, 2009.  PMC2804995.

Michael YL, Keast EM, Chaudhury H, Day K, Mahmood A, Sarte AF. Revising the senior walking environmental assessment tool. Preventative Medicine 48:247-249, 2009.  NIHMS106679.

Price JL, McKeel DW, Jr., Buckles VD, Roe CM, Xiong C, Grundman M, Hansen LA, Petersen RC, Parisi JE, Dickson DW, Smith CD, Davis DG, Schmitt FA, Markesbery WR, Kaye J, Kurlan R, Hulette C, Kurland BF, Higdon R, Kukull W, Morris JC. Neuropathology of nondemented aging: presumptive evidence for preclinical Alzheimer disease. Neurobiology of Aging 30:1026-1036, 2009.  PMC2737680.

Quinn J, Clark C. Failure of biomarkers in clinical trials of Alzheimer's disease:  Blaming the messenger? Journal of  Alzheimers Disease Epub ahead of print 2009. Not a peer-reviewed journal article.

Quinn J, Crane S, Harris C, Wadworth T. Copper in Alzheimer’s disease: too much or too little? . Expert Reviews in Neurotherapeutics 9:631-639, 2009.  PMC Journal in Process.

Roher AE, Esh CL, Kokjohn TA, Castano EM, Van Vickle GD, Kalback WM, Patton RL, Luehrs DC, Daugs ID, Kuo YM, Emmerling MR, Soares H, Quinn JF, Kaye J, Connor DJ, Silverberg NB, Adler CH, Seward JD, Beach TG, Sabbagh MN. Amyloid beta peptides in human plasma and tissues and their significance for Alzheimer's disease. Alzheimers Dement 5:18-29, 2009. PMC2663406.

Seelye A, Howieson D, Wild K, Sauceda L, Kaye J. Living well with MCI:  Behavioral interventions for older adults with mild cognitive impairment. In: Brougham R, ed. New Directions in Aging Research:  Health and Cognition. New York: Nova Scient Publishers, Inc., 2009.

Silbert LC, Howieson DB, Dodge H, Kaye JA. Cognitive impairment risk: white matter hyperintensity progression matters. Neurology 73:120-125, 2009.  PMC2713187.

Sonnen JA, Larson EB, Brickell K, Crane PK, Woltjer R, Montine TJ, Craft S. Different Patterns of Cerebral Injury in Dementia With or Without Diabetes. Archives of Neurology 66:315-322, 2009.  PMC2766529.

Sonnen JA, Montine KS, Quinn JF, Breitner JC, Montine TJ. Cerebrospinal Fluid Biomarkers in Mild Cognitive Impairment and Dementia. Journal of Alzheimer's Disease, 2009.  PMC2891184

Tian W, Fu Y, Garcia-Elias A, Fernandez-Fernandez JM, Vicente R, Kramer PL, Klein RF, Hitzemann R, Orwoll ES, Wilmot B, McWeeney S, Valverde MA, Cohen DM. A loss-of-function nonsynonymous polymorphism in the osmoregulatory TRPV4 gene is associated with human hyponatremia. Proc Natl Acad Sci U S A 106:14034-14039, 2009.  PMC2729015.

2008

Bekris LM, Millard SP, Galloway NM, Vuletic S, Albers JJ, Li G, Galasko DR, DeCarli C, Farlow MR, Clark CM, Quinn JF, Kaye JA, Schellenberg GD, Tsuang D, Peskind ER, Yu CE. Multiple SNPs within and surrounding the apolipoprotein E gene influence cerebrospinal fluid apolipoprotein E protein levels. Journal of Alzheimers Disease 13:255-266, 2008.

Boise L. Ethnicity and the experience of dementia. Berkshire: McGraw-Hill; 52-69, 2008.

Bowman G, Quinn J. Alzheimer's disease and the blood-brain barrier:  Past present and future. Aging Health 4:47-57, 2008.  PMC2778025.

Buenafe AC, Zwickey H, Moes N, Oken B, Jones RE. A telemetric study of physiologic changes in mice with induced autoimmune encephalomyelitis. Lab Animal 37:361-368, 2008.

Calabrese C, Gregory WL, Leo M, Kraemer D, Bone K, Oken B. Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: A randomized, double-blind, placebo-controlled trial. Journal of Alternative and Complementary Medicine 14:707-713, 2008.

Carlson NE, Moore MM, Dame A, Howieson D, Silbert LC, Quinn JF, Kaye JA. Trajectories of brain loss in aging and the development of cognitive impairment. Neurology 70:828-833, 2008.

Dodge H, Shen C, Ganguli M. Application of the pattern-mixture latent trajectory model in an epidemiological study with non-ignorable missingness. The Journal of Data Science 6:231-246, 2008.

Dodge HH, Kita Y, Takechi H, Hayakawa T, Ganguli M, Ueshima H. Healthy cognitive aging and leisure activities among the oldest old in Japan: Takashima study. J Gerontol A Biol Sci Med Sci 63:1193-1200, 2008.  PMC2646000.

Dodge HH, Zitzelberger T, Oken BS, Howieson D, Kaye J. A randomized placebo-controlled trial of ginkgo biloba for the prevention of cognitive decline. Neurology 70:1809-1817, 2008.  PMC2639649.

Erten-Lyons D. When should patients with Alzheimer disease stop driving? Neurology 70:e45-47, 2008.

Erten-Lyons D, Jacobs A, Kramer P, Grupe A, Kaye J. The FAS gene is associated with brain volume in mild cogntive Impairment and Alzheimer's disease. Neurology 70:A103, 2008.

Erten-Lyons D, Oken B, Woltjer RL, Quinn J. Relapsing polychondritis: an uncommon cause of dementia. Journal of Neurology, Neurosurgery, and Psychiatry 79:609-610, 2008.

Fleisher AS, Raman R, Siemers ER, Becerra L, Clark CM, Dean RA, Farlow MR, Galvin JE, Peskind ER, Quinn JF, Sherzai A, Sowell BB, Aisen PS, Thal LJ. Phase II safety trial targeting amyloid beta production with a gamma-secretase inhibitor in Alzheimer disease. Archives of Neurology 65:1031-1038, 2008.  PMC2682361.

Hayes T, Pavel M, Kaye J. An approach for deriving continuous health assessment indicators from in-home sensor data. In: Mihailidis A, Boger J, Kautz H, Normie L, eds. Technology and Aging: Selected papers from the 2007 International Conference on Technology and Aging. Amsterdam, The Netherlands: IOS Press; 130-137, 2008.

Hayes TL, Abendroth F, Adami A, Pavel M, Zitzelberger TA, Kaye JA. Unobtrusive assessment of activity patterns associated with mild cognitive impairment. Alzheimers and  Dementia 4:395-405, 2008.  PMC2664300.

Hill JM, Ball MJ, Neumann DM, Azcuy AM, Bhattacharjee PS, Bouhanik S, Clement C, Lukiw WJ, Foster TP, Kumar M, Kaufman HE, Thompson HW. The high prevalence of herpes simplex virus type 1 DNA in human trigeminal ganglia is not a function of age or gender. Journal of Virology 82:8230-8234, 2008.  PMC2519549.

Howieson DB, Carlson NE, Moore MM, Wasserman D, Abendroth CD, Payne-Murphy J, Kaye JA. Trajectory of mild cognitive impairment onset. Journal of the International Neuropsychological Society 14:192-198, 2008.

Hutter CM, Samii A, Factor SA, Nutt JG, Higgins DS, Bird TD, Griffith A, Roberts JW, Leis BC, Montimurro JS, Kay DM, Edwards KL, Payami H, Zabetian CP. Lack of evidence for an association between UCHL1 S18Y and Parkinson's disease. European Journal of Neurology 15:134-139, 2008.

Kay DM, Factor SA, Samii A, Higgins DS, Griffith A, Roberts JW, Leis BC, Nutt JG, Montimurro JS, Keefe RG, Atkins AJ, Yearout D, Zabetian CP, Payami H. Genetic association between alpha-synuclein and idiopathic Parkinson's disease. Am J Med Genet B Neuropsychiatr Genet 147B:1222-1230, 2008.

Kaye J. Home-based technologies: A new paradigm for conducting dementia prevention trials. Alzheimer's & Dementia 4:S60-S66, 2008.

Kaye J, Hayes T, Zitzelberger T, Yeargers J, Pavel M, Jimison H, Larimer N, Payne-Murphy J, Earl E, Wild K, Boise L, Williams D, Lundell J, Dishman E. Deploying wide scale in-home assessment technology. In: Mihailidis A, Boger J, Kautz H, Normie L, eds. Technology and Aging: Selected papers from the 2007 International Conference on Technology and Aging. Amsterdam, The Netherlands: IOS Press; 19-26, 2008.

Khachaturian ZS, Petersen RC, Gauthier S, Buckholtz N, Corey-Bloom JP, Evans B, Fillit H, Foster N, Greenberg B, Grundman M, Sano M, Simpkins J, Schneider LS, Weiner MW, Galasko D, Hyman B, Kuller L, Schenk D, Snyder S, Thomas RG, Tuszynski MH, Vellas B, Wurtman RJ, Snyder PJ, Frank RA, Albert M, Doody R, Ferris S, Kaye J, Koo E, Morrison-Bogorad M, Reisberg B, Salmon DP, Gilman S, Mohs R, Aisen PS, Breitner JC, Cummings JL, Kawas C, Phelps C, Poirier J, Sabbagh M, Touchon J, Khachaturian AS, Bain LJ. A roadmap for the prevention of dementia: the inaugural Leon Thal Symposium. Alzheimer's & Dementia 4:156-163, 2008.  PMC2544623.

Lee JH, Cheng R, Graff-Radford N, Foroud T, Mayeux R. Analyses of the National Institute on Aging Late-Onset Alzheimer's Disease Family Study: implication of additional loci. Archives of Neurology 65:1518-1526, 2008.  PMC2694670.

Leverenz JB, Hamilton R, Tsuang DW, Schantz A, Vavrek D, Larson EB, Kukull WA, Lopez O, Galasko D, Masliah E, Kaye J, Woltjer R, Clark C, Trojanowski JQ, Montine TJ. Empiric refinement of the pathologic assessment of Lewy-related pathology in the dementia patient. Brain Pathology 18:220-224, 2008.  PMC2689097.

Liu C, Takahashi M, Li Y, Song S, Dillon TJ, Shinde U, Stork PJ. Ras is required for the cyclic AMP-dependent activation of Rap1 via Epac2. Mol Cell Biol 28:7109-7125, 2008.  PMC2593374.

Lovell MA, Lynn BC, Xiong S, Quinn JF, Kaye J, Markesbery WR. An aberrant protein complex in CSF as a biomarker of Alzheimer disease. Neurology 70:2212-2218, 2008.

Michael Y, McGregor E, Allen J, Fickas S. Observing outdoor activity using global positioning system-enabled cell phones. In: Helal S, Mitra S, Wong J, Chang C, Mokhtari M, eds. Smart Homes and Health Telematics. Ames, IA: Springer, Berlin, Heidelberg; 177-184, 2008.

Nagel CL, Carlson NE, Bosworth M, Michael YL. The relation between neighborhood built environment and walking activity among older adults. American Journal of Epidemiology 168:461-468, 2008.

Oken BS. Placebo effects: Clinical aspects and neurobiology. Brain 131:2812-2823, 2008.

Oken BS, Flegal K, Zajdel D, Kishiyama S, Haas M, Peters D. Expectancy effect: Impact of pill administration on cognitive performance in healthy seniors. Journal of Clinical and Experimental Neuropsychology 30:7-17, 2008.

Pan S, Rush J, Peskind ER, Galasko D, Chung K, Quinn J, Jankovic J, Leverenz JB, Zabetian C, Pan C, Wang Y, Oh JH, Gao J, Zhang J, Montine T, Zhang J. Application of targeted quantitative proteomics analysis in human cerebrospinal fluid using a liquid chromatography matrix-assisted laser desorption/ionization time-of-flight tandem mass spectrometer (LC MALDI TOF/TOF) platform. Journal of Proteome Research 7:720-730, 2008.

Pavel M, Jimison H, Hayes T, Kaye J, Dishman E, WIld K, Williams D. Continuous, Unobtrusive Monitoring for the Assessment of Cognitive Function. In: Hofer SM, Alwin DF, eds. Handbook of Cognitive Aging: Interdisciplinary Perspetives. Thousand Oaks, CA: Sage Publications, Inc.; Chapter 31, 2008.

Pavel M, Jimison H, Hayes T, Kaye J, Dishman E, Wild K, Williams D. Continuous, unobtrusive monitoring for the assessment of cognitive function. In: Hofer S, Alwin D, eds. Handbook of Cognitive Aging: Interdisciplinary Perspectives. Thousand Oaks, CA.: Sage Publications, Inc., 2008.

Powers KM, Kay DM, Factor SA, Zabetian CP, Higgins DS, Samii A, Nutt JG, Griffith A, Leis B, Roberts JW, Martinez ED, Montimurro JS, Checkoway H, Payami H. Combined effects of smoking, coffee, and NSAIDs on Parkinson's disease risk. Movement Disorders : Official Journal of the Movement Disorder Society 23:88-95, 2008.

Quinn J, Sabbagh MN. Detecting Alzheimer disease before it happens: The key to prevention? Neurology 71:78-79, 2008.

Raber J. AR, apoE, and cognitive function. Horm Behav 53:706-715, 2008.  PMC2409114.

Reddy PH. Mitochondrial medicine for aging and neurodegenerative diseases. Neuromolecular Medicine 10:291-315, 2008.

Reddy PH, Beal MF. Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease. Trends Mol Med 14:45-53, 2008.

Seelye AM, Howieson DB, Wild KV, Moore MM, Kaye JA. Wechsler Memory Scale-III Faces test performance in patients with mild cognitive impairment and mild Alzheimer's disease. Journal of Clinical and Experimental Neuropsychology:1-7, 2008.  NIHMS# 97312.

Sheldahl LC, Shapiro RA, Bryant DN, Koerner IP, Dorsa DM. Estrogen induces rapid translocation of estrogen receptor beta, but not estrogen receptor alpha, to the neuronal plasma membrane. Neuroscience 153:751-761, 2008.  PMC2587260.

Shinto L, Calabrese C, Morris C, Yadav V, Griffith D, Frank R, Oken BS, Baldauf-Wagner S, Bourdette D. A randomized pilot study of naturopathic medicine in multiple sclerosis. Journal of Alternative and Complementary Medicine 14:489-496, 2008.

Silbert LC, Nelson C, Howieson DB, Moore MM, Kaye JA. Impact of white matter hyperintensity volume progression on rate of cognitive and motor decline. Neurology 71:108-113, 2008.  PMC2676966.

Sonnen JA, Breitner JC, Lovell MA, Markesbery WR, Quinn JF, Montine TJ. Free radical-mediated damage to brain in Alzheimer's disease and its transgenic mouse models. Free Radic Biol Med 45:219-230, 2008.  PMC2459222.

Sonnen JA, Montine KS, Quinn JF, Kaye JA, Breitner JC, Montine TJ. Biomarkers for cognitive impairment and dementia in elderly people. Lancet Neurology 7:704-714, 2008.  PMC2710375.

Szekely CA, Green RC, Breitner JC, Ostbye T, Beiser AS, Corrada MM, Dodge HH, Ganguli M, Kawas CH, Kuller LH, Psaty BM, Resnick SM, Wolf PA, Zonderman AB, Welsh-Bohmer KA, Zandi PP. No advantage of A beta 42-lowering NSAIDs for prevention of Alzheimer dementia in six pooled cohort studies. Neurology 70:2291-2298, 2008.

Wadsworth TL, Bishop JA, Pappu AS, Woltjer RL, Quinn JF. Evaluation of coenzyme q as an antioxidant strategy for Alzheimer's disease. Journal of  Alzheimers Disease 14:225-234, 2008.  NIHMS#102025.

Wahbeh H, Elsas SM, Oken BS. Mind-body interventions: Applications in neurology. Neurology 70:2321-2328, 2008.

Wahbeh H, Kishiyama SS, Zajdel D, Oken BS. Salivary cortisol awakening response in mild Alzheimer disease, caregivers, and noncaregivers. Alzheimer's Disease and Associated Disorders 22:181-183, 2008.  PMC - Journal in Process.

Wang W, Shinto L, Connor WE, Quinn JF. Nutritional biomarkers in Alzheimer's disease: The association between carotenoids, n-3 fatty acids, and dementia severity. Journal of  Alzheimers Disease 13:31-38, 2008.

Wild K, Boise L, Lundell J, Foucek A. Unobtrusive in-home monitoring of cognitive and physical health: Reactions and perceptions of Older Adults. Journal of Applied Gerontology 27:181-200, 2008.  PMC2629437.

Wild K, Howieson D, Webbe F, Seelye A, Kaye J. The status of computerized cognitive testing in aging: A systematic review. Alzheimers and  Dementia 4:428-437, 2008.  PMC2645803.

Wilmot B, McWeeney SK, Nixon RR, Montine TJ, Laut J, Harrington CA, Kaye JA, Kramer PL. Translational gene mapping of cognitive decline. Neurobiology of Aging 29:524-541, 2008.  PMC2684335.

Woltjer RL, Sonnen JA, Sokal I, Rung LG, Yang W, Kjerulf JD, Klingert D, Johnson C, Rhew I, Tsuang D, Crane PK, Larson EB, Montine TJ. Quantitation and Mapping of Cerebral Detergent-Insoluble Proteins in the Elderly. Brain Pathology:Epub ahead of print, 2008.  NIHMSID #69069.

Zhang J, Sokal I, Peskind ER, Quinn JF, Jankovic J, Kenney C, Chung KA, Millard SP, Nutt JG, Montine TJ. CSF multianalyte profile distinguishes Alzheimer and Parkinson diseases. American Journal of Clinical Pathology 129:526-529, 2008.  PMC2688655.

2007

Borenstein AR, Mortimer JA, Schofield E, Wu Y, Salmon DP, Gamst A, Olichney J, Thal LJ, Silbert L, Kaye J, Craig UL, Schellenberg GD, and Galasko DR. Cycad exposure and risk of dementia, MCI, and PDC in the Chamorro population of Guam. Neurology. 68(21): p. 1764-71, 2007.

Bowman GL, Kaye JA, Moore M, Waichunas D, Carlson NE, Quinn JF. Blood-brain barrier impairment in Alzheimer's disease: stability and functional significance. Neurology. 2007 May 22;68(21):1809-14.

Carlson N, Moore M, Dame A, Howieson D, Silbert L, Quinn J, and Kaye J. Trajectories of brain loss in aging and the development of cognitive impairment. Neurology. In Press, 2007.

Chaves ML, Camozzato AL, Godinho C, Kochhann R, Schuh A, de Almeida VL, Kaye J. Validity of the clinical dementia rating scale for the detection and staging of dementia in Brazilian patients. Alzheimer Dis Assoc Disord. 21(3): p. 210-7, 2007.

Chun LS, Samii A, Hutter CM, Griffith A, Roberts JW, Leis BC, Mosley AD, Wander PL, Edwards KL, Payami H, and Zabetian CP. DBH -1021C-->T does not modify risk or age at onset in Parkinson's disease. Ann Neurol. 62(1): p. 99-101, 2007.

Coehlo DP, Hooker K, Bowman S. Institutional placement of persons with dementia: what predicts occurrence and timing? J Fam Nurs. 2007 May;13(2):253-77.

Dodge H, Zitzelberger T, Oken B, Howieson D, and Kaye J. A Randomized Placebo-Controlled Trial of Ginkgo Biloba for the Prevention of Cognitive Decline. Neurology. In Press, 2007.

Galasko D, Salmon D, Gamst A, Olichney J, Thal LJ, Silbert L, Kaye J, Brooks P, Adonay R, Craig UK, Schellenberg G, and Borenstein AR. Prevalence of dementia in Chamorros on Guam: relationship to age, gender, education, and APOE. Neurology. 68(21): p. 1772-81, 2007.

Gordon D, Haynes C, Yang Y, Kramer PL, and Finch SJ. Linear trend tests for case-control genetic association that incorporate random phenotype and genotype misclassification error. Genet Epidemiol. 31(8): p. 853-70, 2007.

Hayes T, Pavel M, and Kaye J. An approach for deriving continuous health assessment indicators from in-home sensor data. Technology and Aging (IOS Press). In Press, 2007.

Kay DM, Moran D, Moses L, Poorkaj P, Zabetian CP, Nutt J, Factor SA, Yu CE, Montimurro JS, Keefe RG, Schellenberg GD, Payami H. Heterozygous parkin point mutations are as common in control subjects as in Parkinson's patients.  Ann Neurol. 2007 Jan;61(1):47-54.

Kaye J. Home-based technologies: a new paradigm for conducting dementia prevention trials. Alzheimer's & Dementia. In Press, 2007.

Kaye J, Hayes T, Zitzelberger T, Yeargers J, Pavel M, Jimison H, Larimer N, Payne-Murphy J, Wild K, Boise L, Williams D, Lundell J, and Dishman E. Deploying wide scale in-home assessment technology. Technology and Aging (IOS Press). In Press, 2007.

Kaye JA, Moore MM, Galasko D, Craig UK, Adonay R, and Silbert LC. Brain volumes in Guam dementia vs. Parkinson dementia complex vs. aging Charmorro adults. Neurology. 69(2): p. 196-199, 2007.

Kaye J, Zitzelberger T.  Living laborabory tests new models of home assessment.  Aging Today, 28 (5): p. 7-10, 2007.

Leen T, Zhengdong L, Hayes T, and Kaye J. Detection of early cognitive loss from medication adherence behavior. Technology and Aging (IOS Press). In Press.

Li G, Sokal I, Quinn J, Leverenz J, Brodey M, Schellenberg G, Kaye J, Raskind M, Zhang J, Peskind E, and Montine T. CSF tau/Abeta42 ratio for increased risk of mild cognitive impairment:  A follow-up study. Neurology. 69(7): p. 631-639, 2007.

Lundell J, Hayes TL, Vurgun S, Ozertem U, Kimel J, Kaye J, Guilak F, Pavel M. Continuous activity monitoring and intelligent contextual prompting to improve medication adherence.  Conf Proc IEEE Eng Med Biol Soc. 2007;1:6286-9, 2007.

Montine TJ, Quinn J, Kaye J, Morrow JD.F(2)-isoprostanes as biomarkers of late-onset Alzheimer's disease. J Mol Neurosci. 33(1):p. 114-9, 2007.

Nakashima-Yasuda H, Uryu K, Robinson J, Xie S, Hurtig H, Duda J, Arnold S, Siderowf A, Grossman M, Leverenz J, Lopez O, Hamilton R, Tsuang D, Galasko D, Masliah E, Kaye J, Woltjer R, Clark C, Montine T, Lee V, and Trojanowski J. Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases. Acta Neuropathologica. 114: p. 221-229, 2007.

Pan S, Zhu D, Quinn JF, Peskind ER, Montine TJ, Lin B, Goodlett DR, Taylor G, Eng J, Zhang J. A combined dataset of human cerebrospinal fluid proteins identified by multi-dimensional chromatography and tandem mass spectrometry. Proteomics. 2007 Feb;7(3):469-73. Review.
Quinn JF, Bussiere JR, Hammond RS, Montine TJ, Henson E, Jones RE, and Stackman RW, Jr. Chronic dietary alpha-lipoic acid reduces deficits in hippocampal memory of aged Tg2576 mice. Neurobiol Aging. 28(2): p. 213-25, 2007.

Raber J. Role of apolipoprotein E in anxiety. Neural Plast. p. 91236, 2007.

Ray S, Britschgi M, Herbert C, Takeda-Uchimura Y, Boxer A, Blennow K, Friedman LF, Galasko DR, Jutel M, Karydas A, Kaye JA, Leszek J, Miller BL, Minthon L, Quinn JF, Rabinovici GD, Robinson WH, Sabbagh MN, So YT, Sparks DL, Tabaton M, Tinklenberg J, Yesavage JA, Tibshirani R, and Wyss-Coray T. Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins. Nat Med. 13(11): p. 1359-62, 2007.

Roark B, Hosom J, Mitchell M, and Kaye J. Automatically derived spoken language markers for detecting mild cognitive impairment. Technology and Aging (IOS Press). In Press, 2007.

Roark B, Mitchell M, and Hollingshead K. Syntactic complexity measures for detecting Mild Cognitive Impairment, in BioNLP: Biological, Translational and Clinical  Language Processing. The Association for Computational Linguistics: Prague. p. 1-8, 2007.

Sheng P, Zhu D, Quinn JF, Peskind E, Montine TJ, Lin B, Goodlett DR, Taylor G, Eng J, and Zhang J. A combined dataset of human cerebrospinal fluid proteins identified by multidimensional chromatography and tandem mass spectroscopy. Proteomics. 7(3): p. 469-473, 2007.

Shie F and Woltjer R. Manipulation of microglial activation as a therapeutic strategy in Alzheimer's disease. Current Medicinal Chemistry. In Press, 2007.

Sumic A, Michael YL, Carlson NE, Howieson DB, Kaye JA.  Physical Activity and the Risk of Dementia in Oldest Old Journal Of Aging Health.  2007; Apr;19(2): 242-259.

Taylor JP, Hulihan MM, Kachergus JM, Melrose HL, Lincoln SJ, Hinkle KM, Stone JT, Ross OA, Hauser R, Aasly J, Gasser T, Payami H, Wszolek ZK, Farrer MJ. Leucine-rich repeat kinase 1: a paralog of LRRK2 and a candidate gene for Parkinson's disease.  Neurogenetics. 2007Apr;8(2):95102. Epub 2007 Jan 16. PMID: 17225181 [PubMed - in process].

Wahbeh H, Kishiyama S, Zajdel D, and Oken B. Salivary cortisol awakening response in mild Alzheimer's disease, caregivers and non-caregivers. Alzheimer's Disease and Related Disorders. In Press, 2007.

Yang W, Woltjer RL, Sokal I, Pan C, Wang Y, Brodey M, Peskind ER, Leverenz JB, Zhang J, Perl DP, Galasko DR, and Montine TJ. Quantitative proteomics identifies surfactant-resistant alpha-synuclein in cerebral cortex of Parkinsonism-dementia complex of Guam but not Alzheimer's disease or progressive supranuclear palsy. Am J Pathol. 171(3): p. 993-1002, 2007.

Zabetian CP, Hutter CM, Factor SA, Nutt JG, Higgins DS, Griffith A, Roberts JW, Leis BC, Kay DM, Yearout D, Montimurro JS, Edwards KL, Samii A, and Payami H. Association analysis of MAPT H1 haplotype and subhaplotypes in Parkinson's disease. Ann Neurol. 62(2): p. 137-44, 2007.

2006

Abdi F, Quinn JF, Jankovic J, McIntosh M, Leverenz JB, Peskind E, Nixon R,Nutt J, Chung K, Zabetian C, Samii A, Lin M, Hattan S, Pan C, Wang Y, Jin J, Zhu D, Li GJ, Liu Y, Waichunas D, Montine TJ, Zhang J. Detection of biomarkers with a multiplex quantitative proteomic platform incerebrospinal fluid of patients with neurodegenerative disorders. Journal of Alzheimer's Disease. 2006 Aug;9(3):293-348.

Ball M. The essential lesion of Alzheimer's disease:  A surprise in retrospect. Journal of Alzheimer's Disease. 9(3  suppl): p. 29-33, 2006.

Brickell KL, Steinbart EJ, Rumbaugh M, Payami H, Schellenberg GD, Van Deerlin V, Yuan W, Bird TD.    Early-onset Alzheimer disease in families with late-onset Alzheimer disease: a potential important subtype of familial Alzheimer disease. Archives of Neurology  2006 Sep;63(9):1307-11. PMID: 16966510

Calvert JF Jr, Hollander-Rodriguez J, Kaye J, Leahy M. Dementia-free survival among centenarians: an evidence-based review. J Gerontol A Biol Sci Med Sci. 2006 Sep;61(9):951-6.

Cotrell V, Wild K, and Bader T. Medication management and adherence among cognitively impaired older adults. J Gerontol Soc Work. 47(3-4): p. 31-46, 2006.

Elbaz A, Nelson LM, Payami H, Ioannidis JP, Fiske BK, Annesi G, Carmine Belin A, Factor SA, Ferrarese C, Hadjigeorgiou GM, Higgins DS, Kawakami H, Kruger R, Marder KS, Mayeux RP, Mellick GD, Nutt JG, Ritz B, Samii A, Tanner CM, Van Broeckhoven C, Van Den Eeden SK, Wirdefeldt K, Zabetian CP, Dehem M, Montimurro JS, Southwick A, Myers RM, and Trikalinos TA. Lack of replication of thirteen single-nucleotide polymorphisms implicated in Parkinson's disease: a large-scale international study. Lancet Neurol. 5(11): p. 917-23, 2006.

Erten-Lyons D, Howieson D, Moore MM, Quinn J, Sexton G, Silbert L, Kaye J. Brain volume loss in MCI predicts dementia. Neurology. 2006 Jan 24;66(2):233-5.

Galasko D, Bennett DA, Sano M, Marson D, Kaye J, and Edland SD. ADCS prevention instrument project: Assessment of instrumental activities of daily living for community-dwelling elderly individuals in dementia prevention clinical trials. Alzheimer Disease and Associated Disorders. 20 Suppl 3(3): p. S152-S169, 2006.

Hare JF. Intracellular pathways of folded and misfolded amyloid precursor protein degradation. Arch Biochem Biophys. 451(1): p. 79-90, 2006.

Hayes TL, Hunt JM, Adami A, Kaye JA. An electronic pillbox for continuous monitoring of medication adherence. Conf Proc IEEE Eng Med Biol Soc.1: p. 6400-3, 2006.

Kammerman E, Neumann D, Ball M, Lukiw W, and Hill J. Senile plaques in Alzheimer's diseased brains: Possible association of beta-amyloid with herpes simplex virus type 1 (HSV-1) L-particles. Medical  Hypotheses. 66: p. 294-9, 2006.

Kay DM, Bird TD, Zabetian CP, Factor SA, Samii A, Higgins DS, Nutt J, Roberts JW, Griffith A, Leis BC, Montimurro JS, Philpott S, and Payami H. Validity and utility of a LRRK2 G2019S mutation test for the diagnosis of Parkinson's disease. Genet Test. 10(3): p. 221-7, 2006.
Kay DM, Moran D, Moses L, Poorkaj P, Zabetian CP, Nutt J, Factor SA, Yu CE, Montimurro JS, Keefe RG, Schellenberg GD, and Payami H. Heterozygous parkin point mutations are as common in control subjects as in Parkinson's patients. Ann Neurol. 22: p. 22, 2006.

Kay DM, Zabetian CP, Factor SA, Nutt JG, Samii A, Griffith A, Bird TD, Kramer P, Higgins DS, Payami H. Parkinson's disease and LRRK2: frequency of a common mutation in U.S. movement disorder clinics. Mov Disord. 2006 Apr;21(4):519-23
Kaye JA and Hayes T. Home health monitoring:  A system to assess motor and cognitive function. Generations. 30(2): p. 61-63, 2006.

Li D, Parks SB, Kushner JD, Nauman D, Burgess D, Ludwigsen S, Partain J, Nixon RR, Allen CN, Irwin RP, Jakobs PM, Litt M, and Hershberger RE. Mutations of presenilin genes in dilated cardiomyopathy and heart failure. Am J Hum Genet. 79(6): p. 1030-9, 2006.

Lovera J, Bagert B, Smoot KH, Wild K, Frank R, Bogardus K, Oken BS, Whitham RH, Bourdette DN. Correlations of Perceived Deficits Questionnaire of Multiple Sclerosis Quality of Life Inventory with Beck Depression Inventory and neuropsychological tests. J Rehabil Res Dev. 2006 Jan-Feb;43(1):73-82.

Maia AL, Godinho C, Ferreira ED, Almeida V, Schuh A, Kaye J, Chaves ML. Application of the Brazilian version of the CDR scale in samples of dementia patients Arq Neuropsiquiatr. 2006 Jun;64 2B:485-9. Portuguese.

Manczak, Maria Thimmappa S. Anekonda, Edward Henson, Byung S. Park, Joseph Quinn, and P. Hemachandra Reddy Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression Human Molecular Genetics, 1 May 2006; 15: 1437 - 1449.

Michael Y, Beard T, Choi D, Farquhar S, and Carlson N. Measuring the influence of built neighborhood environments on walking in older adults. J Aging Phys Act. 14(3): p. 302-12, 2006.

Morgan NV, Westaway SK, Morton JE, Gregory A, Gissen P, Sonek S, Cangul H, Coryell J, Canham N, Nardocci N, Zorzi G, Pasha S, Rodriguez D, Desguerre I, Mubaidin A, Bertini E, Trembath RC, Simonati A, Schanen C, Johnson CA, Levinson B, Woods CG, Wilmot B, Kramer P, Gitschier J, Maher ER, Hayflick SJ. PLA2G6, encoding a phospholipase A2, is mutated in neurodegenerative disorders with high brain iron. Nat Genet. 2006 Jul;38(7):752-4. PMID: 16783378

Oken BS, Flegal K, Zajdel D, Kishiyama SS, Lovera J, Bagert B, Bourdette DN. Cognition and fatigue in multiple sclerosis: Potential effects of medications with central nervous system activity. J Rehabil Res Dev. 2006 Jan-Feb;43(1):83-90.

Oken BS, Salinsky MC, Elsas SM. Vigilance, alertness, or sustained attention: physiological basis and measurement. Clin Neurophysiol. 2006 Sep;117(9):1885-1901.

Oken BS, Zajdel D, Kishiyama S, Flegal K, Dehen C, Haas M, Kraemer DF, Lawrence J, Leyva J. Randomized, controlled, six-month trial of yoga in healthy seniors: effects on cognition and quality of life. Altern Ther Health Med. 2006 Jan-Feb;12(1):40-7.

Pan S, Wang Y, Quinn JF, Peskind ER, Waichunas D, Wimberger JT, Jin J, Li JG, Zhu D, Pan C, Zhang J. Identification of Glycoproteins in Human Cerebrospinal Fluid with a Complementary Proteomic Approach. J Proteome Res. 2006 Oct 6;5(10):2769-2779.

Pavel M, Hayes TL, Adami A, Jimison H, Kaye J.  Unobtrusive assessment of mobility. Conf Proc IEEE Eng Med Biol Soc.1: p. 6277-80, 2006.

Peskind ER, Li G, Shofer J, Quinn JF, Kaye JA, Clark CM, Farlow MR, DeCarli C, Raskind MA, Schellenberg GD, Lee VM, Galasko DR. Age and apolipoprotein E4;allele effects on cerebrospinal fluid beta-amyloid 42 in adults with normal cognition. Arch Neurol. 2006 Jul;63(7):936-9.

Plassman B, Khachaturian A, Townsend J, Ball M, Steffens D, Leslie C, Tschanz J, Norton M, Burke J, Welsh-Bohmer K, Hulette C, R N, Tyrey M, and Breitner J. Comparison of clinical and neuropathological  diagnoses of AD in three epidemiological samples. Alzheimer's & Dementia. 2(1): p. 2-11, 2006.

Quinn JF, Bussiere JR, Hammond RS, Montine TJ, Henson E, Jones RE, Stackman RW Jr. Chronic dietary alpha-lipoic acid reduces deficits in hippocampal memory of aged Tg2576 mice. Neurobiol Aging. 2006 Jan 28;

Quinn J and Kaye J. Healthy Brain Aging, in Handbook of Dementing Illnesses (second addition), J Morris, J Galvin, and D Holtzman, Editors.  Marecel-Dekker: New York, 2006.

Reddy P. Amyloid precursor protein-mediated free radicals and oxidative damage: Implications for the development and progression of Alzheimer's disease. Journal of Neurochemistry. 96: p. 1-13, 2006.

Reddy PH. Mitochondrial oxidative damage in aging and Alzheimer's disease: implications for mitochondrially targeted antioxidant therapeutics. J Biomed Biotechnol. 2006(3): p. 31372, 2006.

Rizk-Jackson AM, Acevedo SF, Inman D, Howieson D, Benice TS, Raber J. Effects of sex on object recognition and spatial navigation in humans. Behav Brain Res. 2006 Oct 16;173(2):181-90. Epub 2006 Aug 2.

Siemers ER, Quinn JF, Kaye J, Farlow MR, Porsteinsson A, Tariot P, Zoulnouni P, Galvin JE, Holtzman DM, Knopman DS, Satterwhite J, Gonzales C, Dean RA, May PC. Effects of a gamma-secretase inhibitor in a randomized study of patients with Alzheimer disease. Neurology. 2006 Feb 28;66(4):602-4.

Silbert LC, Nelson C, Holman S, Eaton R, Oken BS, Lou JS, Kaye JA. Cortical excitability and age-related volumetric MRI changes. Clin Neurophysiol. 2006 May;117(5):1029-36. Epub 2006 Mar 27.

Tandon R, Adak S, Kaye JA. Neural networks for longitudinal studies in Alzheimer's disease. Artif Intell Med. 2006 Mar;36(3):245-55. Epub 2006 Jan 19.

Tractenberg RE, Singer CM, Kaye JA. Characterizing sleep problems in persons with Alzheimer's disease and normal elderly. J Sleep Res. 2006 Mar;15(1):97-103.

Wilmot B, McWeeney SK, Nixon RR, Montine TJ, Laut J, Harrington CA, Kaye JA, and Kramer PL. Translational gene mapping of cognitive decline. Neurobiology of  Aging. 13(Dec 13): p. 1558-1497, 2006.

Zabetian CP, Hutter CM, Yearout D, Lopez AN, Factor SA, Griffith A, Leis BC, Bird TD, Nutt JG, Higgins DS, Roberts JW, Kay DM, Edwards KL, Samii A, Payami H. LRRK2 G2019S in families with Parkinson disease who originated from Europe and the Middle East: evidence of two distinct founding events beginning two millennia ago. American Journal of Human Genetics 2006 Oct;79(4):752-8. PMID: 16960813

Zabetian CP, Lauricella CJ, Tsuang DW, Leverenz JB, Schellenberg GD, and Payami H. Analysis of the LRRK2 G2019S mutation in Alzheimer's Disease. Arch Neurol. 63(1): p. 156-7, 2006.

2005

Anderson VC, Litvack ZN, Kaye JA. Magnetic resonance approaches to brain aging and Alzheimer disease-associated neuropathology. Topics in Magnetic Resonance Imaging 16:439-452, 2005.  

Boise L. Improving dementia care through physician education:  Some challenges. Clinical Gerontologist 29:3-10, 2005.  

Boise L. Diagnosing dementia: What to tell the patient and family. Geriatrics and Aging 8:48-51, 2005.  

Cui JG, Zhao Y, Lukiw WJ. Isolation of high spectral quality RNA using run-on gene transcription; application to gene expression profiling of human brain. Cell Mol Neurobiol 25:789-794, 2005. 

Dowling GA, Mastick J, Colling E, Carter JH, Singer CM, Aminoff MJ. Melatonin for sleep disturbances in Parkinson's disease. Sleep Med 6:459-466, 2005.  

Erten-Lyons D, Ferguson F, Howieson D, Moore M, Silbert L, Quinn J, Kaye J. Elderly with more medical illneses have smaller brains and are more resistant to cognitive decline. Neurology 64 (suppl 1):A230, 2005. 

Fleisher A, Grundman M, Jack CR, Jr., Petersen RC, Taylor C, Kim HT, Schiller DH, Bagwell V, Sencakova D, Weiner MF, DeCarli C, DeKosky ST, van Dyck CH, Thal LJ. Sex, apolipoprotein E epsilon 4 status, and hippocampal volume in mild cognitive impairment. Archives of Neurology 62:953-957, 2005.  

Hall DA, Leehey MA, Filley CM, Steinbart E, Montine T, Schellenberg GD, Bosque P, Nixon R, Bird T. PRNP H187R mutation associated with neuropsychiatric disorders in childhood and dementia. Neurology 64:1304-1306, 2005.  

Hill J, Gebhardt B, Azcuy A, Matthews K, Lukiw W, Steiner I, Thompson H, Ball M. Can a herpes simplex virus type 1 neuroinvasive score be correlated to other risk factors in Alzheimer's disease? Medical  Hypotheses 64:320-327, 2005.  

Hill J, Steiner I, Matthews K, Trahan S, Foster T, Ball M. Statins lower the risk of developing Alzheimer's disease by limiting lipid raft endocytosis and decreasing the neuronal spread of Herpes simplex virus type 1. Medical  Hypotheses 64:53-58, 2005.  

Kay DM, Kramer P, Higgins D, Zabetian CP, Payami H. Escaping Parkinson's disease: a neurologically healthy octogenarian with the LRRK2 G2019S mutation. Movement Disorders : Official Journal of the Movement Disorder Society 20:1077-1078, 2005.  

Kaye J, Carlson N, Moore M, Dame A, Howieson D. The clinical transition to dementia is characterized by a two-phase process of accelerating brain loss. Neurology 64 (suppl 1):A390, 2005.  

Kaye J, Moore M, Galasko D, Miller F, Craig U, Silbert L, Adonay R. Healthy Chamorro adults and those with Marianas dementia (MD) are distinguished by patterns of cortical atrophy which differ from European and African American elderly. Neurology (suppl) 64:A391, 2005.  

Kaye JA, Moore MM, Dame A, Quinn J, Camicioli R, Howieson D, Corbridge E, Care B, Nesbit G, Sexton G. Asynchronous regional brain volume losses in presymptomatic to moderate AD. Journal of Alzheimer's Disease 8:51-56, 2005.  

Kishiyama SS, Leahy MJ, Zitzelberger TA, Guariglia R, Zajdel DP, Calvert JF, Jr., Kaye JA, Oken BS. Patterns of dietary supplement usage in demographically diverse older people. Altern Ther Health Med 11:48-53, 2005.  PMC1255934.

Leahy MJ, Thurber D, Calvert JF, Jr. Benefits and challenges of research with the oldest old for participants and nurses. Geriatric nursing (New York, N.Y.) 26:21-28, 2005.  

Montine T, Quinn J, Montine K, Kaye J, Breitner J. Quantitative in vivo biomarkers of oxidative damage and their application to the diagnosis and management of Alzheimer's disease. Journal of Alzheimer's Disease 8:359-367, 2005.  

Montine TJ, Montine KS, McMahan W, Markesbery WR, Quinn JF, Morrow JD. F2-isoprostanes in Alzheimer and other neurodegenerative diseases. Antioxid Redox Signal 7:269-275, 2005.  

Morris J, Quaid K, Holtzman D, Kantarcic K, Kaye J, Reiman E, Klunk W, Siemers E. Role of biomarkers in studies of presymptomatic Alzheimer's disease. Alzheimer's & Dementia 1:145-151, 2005.  

Nixon RR. Prion-associated increases in Src-family kinases. The Journal of Biological Chemistry 280:2455-2462, 2005.  

Payami H, Zhu M, Montimurro J, Keefe R, McCulloch CC, Moses L. One step closer to fixing association studies: evidence for age- and gender-specific allele frequency variations and deviations from Hardy-Weinberg expectations in controls. Hum Genet 118:322-330, 2005.  

Peskind ER, Riekse R, Quinn JF, Kaye J, Clark CM, Farlow MR, Decarli C, Chabal C, Vavrek D, Raskind MA, Galasko D. Safety and acceptability of the research lumbar puncture. Alzheimer Disease and Associated Disorders 19:220-225, 2005.  

Petersen RC, Thomas RG, Grundman M, Bennett D, Doody R, Ferris S, Galasko D, Jin S, Kaye J, Levey A, Pfeiffer E, Sano M, van Dyck CH, Thal LJ. Vitamin E and donepezil for the treatment of mild cognitive impairment. N Engl J Med 352:2379-2388, 2005.  

Quinn J, Kulhanek D, Nowlin J, Jones R, Pratico D, Rokach J, Stackman R. Chronic melatonin therapy fails to alter amyloid burden or oxidative damage in old Tg2576 mice: implications for clinical trials. Brain Res 1037:209-213, 2005.  

Reddy PH, Beal MF. Are mitochondria critical in the pathogenesis of Alzheimer's disease? Brain research. Brain Research Reviews 49:618-632, 2005.  

Reddy PH, Mani G, Park BS, Jacques J, Murdoch G, Whetsell W, Jr., Kaye J, Manczak M. Differential loss of synaptic proteins in Alzheimer's disease: implications for synaptic dysfunction. Journal of Alzheimer's Disease 7:103-117; discussion 173-180, 2005.  

Robertson J, Curley J, Kaye J, Quinn J, Pfankuch T, Raber J. ApoE isoforms and measures of anxiety in probable AD patients and Apoe-/- mice. Neurobiology of Aging 26:637-643, 2005.  

Tractenberg RE, Singer CM, Kaye JA. Symptoms of sleep disturbance in persons with Alzheimer's disease and normal elderly. Journal of Sleep Research 14:177-185, 2005.  

Vuletic S, Peskind ER, Marcovina SM, Quinn JF, Cheung MC, Kennedy H, Kaye JA, Jin LW, Albers JJ. Reduced CSF PLTP activity in Alzheimer's disease and other neurologic diseases; PLTP induces ApoE secretion in primary human astrocytes in vitro. J Neurosci Res 80:406-413, 2005.  

Woltjer RL, Cimino PJ, Boutte AM, Schantz AM, Montine KS, Larson EB, Bird T, Quinn JF, Zhang J, Montine TJ. Proteomic determination of widespread detergent-insolubility including Abeta but not tau early in the pathogenesis of Alzheimer's disease. The FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology 19:1923-1925, 2005.  

Zhang J, Goodlett DR, Peskind ER, Quinn JF, Zhou Y, Wang Q, Pan C, Yi E, Eng J, Aebersold RH, Montine TJ. Quantitative proteomic analysis of age-related changes in human cerebrospinal fluid. Neurobiology of Aging 26:207-227, 2005.  

Zhang J, Goodlett DR, Quinn JF, Peskind E, Kaye JA, Zhou Y, Pan C, Yi E, Eng J, Wang Q, Aebersold RH, Montine TJ. Quantitative proteomics of cerebrospinal fluid from patients with Alzheimer disease. Journal of Alzheimer's Disease 7:125-133; discussion 173-180, 2005.

2005

Anderson VC, Litvack ZN, Kaye JA. Magnetic resonance approaches to brain aging and Alzheimer disease-associated neuropathology. Topics in Magnetic Resonance Imaging 16:439-452, 2005.

Boise L. Improving dementia care through physician education:  Some challenges. Clinical Gerontologist 29:3-10, 2005.

Boise L. Diagnosing dementia: What to tell the patient and family. Geriatrics and Aging 8:48-51, 2005.

Cui JG, Zhao Y, Lukiw WJ. Isolation of high spectral quality RNA using run-on gene transcription; application to gene expression profiling of human brain. Cell Mol Neurobiol 25:789-794, 2005.

Dowling GA, Mastick J, Colling E, Carter JH, Singer CM, Aminoff MJ. Melatonin for sleep disturbances in Parkinson's disease. Sleep Med 6:459-466, 2005.

Erten-Lyons D, Ferguson F, Howieson D, Moore M, Silbert L, Quinn J, Kaye J. Elderly with more medical illneses have smaller brains and are more resistant to cognitive decline. Neurology 64 (suppl 1):A230, 2005.

Fleisher A, Grundman M, Jack CR, Jr., Petersen RC, Taylor C, Kim HT, Schiller DH, Bagwell V, Sencakova D, Weiner MF, DeCarli C, DeKosky ST, van Dyck CH, Thal LJ. Sex, apolipoprotein E epsilon 4 status, and hippocampal volume in mild cognitive impairment. Archives of Neurology 62:953-957, 2005.

Hall DA, Leehey MA, Filley CM, Steinbart E, Montine T, Schellenberg GD, Bosque P, Nixon R, Bird T. PRNP H187R mutation associated with neuropsychiatric disorders in childhood and dementia. Neurology 64:1304-1306, 2005.

Hill J, Gebhardt B, Azcuy A, Matthews K, Lukiw W, Steiner I, Thompson H, Ball M. Can a herpes simplex virus type 1 neuroinvasive score be correlated to other risk factors in Alzheimer's disease? Medical  Hypotheses 64:320-327, 2005.

Hill J, Steiner I, Matthews K, Trahan S, Foster T, Ball M. Statins lower the risk of developing Alzheimer's disease by limiting lipid raft endocytosis and decreasing the neuronal spread of Herpes simplex virus type 1. Medical  Hypotheses 64:53-58, 2005.

Kay DM, Kramer P, Higgins D, Zabetian CP, Payami H. Escaping Parkinson's disease: a neurologically healthy octogenarian with the LRRK2 G2019S mutation. Movement Disorders : Official Journal of the Movement Disorder Society 20:1077-1078, 2005.

Kaye J, Carlson N, Moore M, Dame A, Howieson D. The clinical transition to dementia is characterized by a two-phase process of accelerating brain loss. Neurology 64 (suppl 1):A390, 2005.

Kaye J, Moore M, Galasko D, Miller F, Craig U, Silbert L, Adonay R. Healthy Chamorro adults and those with Marianas dementia (MD) are distinguished by patterns of cortical atrophy which differ from European and African American elderly. Neurology (suppl) 64:A391, 2005.

Kaye JA, Moore MM, Dame A, Quinn J, Camicioli R, Howieson D, Corbridge E, Care B, Nesbit G, Sexton G. Asynchronous regional brain volume losses in presymptomatic to moderate AD. Journal of Alzheimer's Disease 8:51-56, 2005.

Kishiyama SS, Leahy MJ, Zitzelberger TA, Guariglia R, Zajdel DP, Calvert JF, Jr., Kaye JA, Oken BS. Patterns of dietary supplement usage in demographically diverse older people. Altern Ther Health Med 11:48-53, 2005.  PMC1255934.

Leahy MJ, Thurber D, Calvert JF, Jr. Benefits and challenges of research with the oldest old for participants and nurses. Geriatric nursing (New York, N.Y.) 26:21-28, 2005.

Montine T, Quinn J, Montine K, Kaye J, Breitner J. Quantitative in vivo biomarkers of oxidative damage and their application to the diagnosis and management of Alzheimer's disease. Journal of Alzheimer's Disease 8:359-367, 2005.

Montine TJ, Montine KS, McMahan W, Markesbery WR, Quinn JF, Morrow JD. F2-isoprostanes in Alzheimer and other neurodegenerative diseases. Antioxid Redox Signal 7:269-275, 2005.

Morris J, Quaid K, Holtzman D, Kantarcic K, Kaye J, Reiman E, Klunk W, Siemers E. Role of biomarkers in studies of presymptomatic Alzheimer’s disease. Alzheimer's & Dementia 1:145-151, 2005.

Nixon RR. Prion-associated increases in Src-family kinases. The Journal of Biological Chemistry 280:2455-2462, 2005.

Payami H, Zhu M, Montimurro J, Keefe R, McCulloch CC, Moses L. One step closer to fixing association studies: evidence for age- and gender-specific allele frequency variations and deviations from Hardy-Weinberg expectations in controls. Hum Genet 118:322-330, 2005.

Peskind ER, Riekse R, Quinn JF, Kaye J, Clark CM, Farlow MR, Decarli C, Chabal C, Vavrek D, Raskind MA, Galasko D. Safety and acceptability of the research lumbar puncture. Alzheimer Disease and Associated Disorders 19:220-225, 2005.

Petersen RC, Thomas RG, Grundman M, Bennett D, Doody R, Ferris S, Galasko D, Jin S, Kaye J, Levey A, Pfeiffer E, Sano M, van Dyck CH, Thal LJ. Vitamin E and donepezil for the treatment of mild cognitive impairment. N Engl J Med 352:2379-2388, 2005.

Quinn J, Kulhanek D, Nowlin J, Jones R, Pratico D, Rokach J, Stackman R. Chronic melatonin therapy fails to alter amyloid burden or oxidative damage in old Tg2576 mice: implications for clinical trials. Brain Res 1037:209-213, 2005.

Reddy PH, Beal MF. Are mitochondria critical in the pathogenesis of Alzheimer's disease? Brain research. Brain Research Reviews 49:618-632, 2005.

Reddy PH, Mani G, Park BS, Jacques J, Murdoch G, Whetsell W, Jr., Kaye J, Manczak M. Differential loss of synaptic proteins in Alzheimer's disease: implications for synaptic dysfunction. Journal of Alzheimer's Disease 7:103-117; discussion 173-180, 2005.

Robertson J, Curley J, Kaye J, Quinn J, Pfankuch T, Raber J. ApoE isoforms and measures of anxiety in probable AD patients and Apoe-/- mice. Neurobiology of Aging 26:637-643, 2005.

Tractenberg RE, Singer CM, Kaye JA. Symptoms of sleep disturbance in persons with Alzheimer's disease and normal elderly. Journal of Sleep Research 14:177-185, 2005.

Vuletic S, Peskind ER, Marcovina SM, Quinn JF, Cheung MC, Kennedy H, Kaye JA, Jin LW, Albers JJ. Reduced CSF PLTP activity in Alzheimer's disease and other neurologic diseases; PLTP induces ApoE secretion in primary human astrocytes in vitro. J Neurosci Res 80:406-413, 2005.

Woltjer RL, Cimino PJ, Boutte AM, Schantz AM, Montine KS, Larson EB, Bird T, Quinn JF, Zhang J, Montine TJ. Proteomic determination of widespread detergent-insolubility including Abeta but not tau early in the pathogenesis of Alzheimer's disease. The FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology 19:1923-1925, 2005.

Zhang J, Goodlett DR, Peskind ER, Quinn JF, Zhou Y, Wang Q, Pan C, Yi E, Eng J, Aebersold RH, Montine TJ. Quantitative proteomic analysis of age-related changes in human cerebrospinal fluid. Neurobiology of Aging 26:207-227, 2005.

Zhang J, Goodlett DR, Quinn JF, Peskind E, Kaye JA, Zhou Y, Pan C, Yi E, Eng J, Wang Q, Aebersold RH, Montine TJ. Quantitative proteomics of cerebrospinal fluid from patients with Alzheimer disease. Journal of Alzheimer's Disease 7:125-133; discussion 173-180, 2005.

2004

Adair JC, Charlie J, Dencoff JE, Kaye JA, Quinn JF, Camicioli RM, Stetler-Stevenson WG, Rosenberg GA. Measurement of gelatinase B (MMP-9) in the cerebrospinal fluid of patients with vascular dementia and Alzheimer disease. Stroke 35:e159-162, 2004.

Adak S, Illouz K, Gorman W, Tandon R, Zimmerman EA, Guariglia R, Moore MM, Kaye JA. Predicting the rate of cognitive decline in aging and early Alzheimer disease. Neurology 63:108-114, 2004.

Boise L, Neal M, Kaye J. Dementia assessment in primary care: Results from a study in three managed care systems. Journal of Gerontology:  Medical Sciences 59:M621-622, 2004.

Boise L, White D. The Family’s role in person-centered care:  Practice considerations. Journal of Psychosocial Nursing 42:12-20, 2004.

Bongers G, Leurs R, Robertson J, Raber J. Role of H(3)-receptor-mediated signaling in anxiety and cognition in wild-type and Apoe(-/-) mice. Neuropsychopharmacology 29:441-449, 2004.

Connell C, Boise L, Stuckey J, Holmes S, Hudson M. Attitudes toward the diagnosis and disclosure of dementia among primary care physicians and family caregivers. The Gerontologist 44:500-507, 2004.

Goddard K, Olson J, Payami H, van der Voet M, Kuivaniemi H, Tromp G. Evidence of linkage and association on chromosome 20 for late onset Alzheimer disease. Neurogenetics 5:121-128, 2004.

Grundman M, Petersen R, Ferris S, Thomas R, Aisen P, Bennett D, Foster N, Jack C, Galasko D, Doody R, Kaye J, Sano M, Mohs R, Gautheir S, Kim H, Jin S, Schultz A, Schafer K, Mulnard R, van Dyck C, Mintzer J, Zamrini E, Cahn-Weiner D, Thal L, Study AsDC. Mild cognitive impairment can be distinguished from Alzheimer’s disease and normal aging for clinical trials. Archives of Neurology 61:59-66, 2004.

Gutala R, Reddy H. The use of real-time analysis in a gene expression study of Alzheimer's disease post-mortem brains. Journal of Neuroscience Methods 132:101-107, 2004.
Hayes T, Pavel M, Kaye J. An unobtrusive in-home monitoring system for detection of key motor changes preceding cognitive decline. In: 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society; San Francisco, California, 2004: 2480-2483.

Howieson D, Moore M, King N, Quinn J, Camicioli R, Silbert L, Dame A, Sexton G, Kaye J. Temporal lobe correlates of episodic and semantic word retrieval in Alzheimer’s disease. Neurology 62 (suppl 5):A236, 2004.

Itzhaki R, Wozniak M, Appelt D, Balin B. Infiltration of the brain by pathogens causes Alzheimer's disease. Neurobiology of Aging 25:619-627, 2004.

Kaye J, Moore M, Galasko D, Craig U, Adonay R, Silbert L. Family history of Mariana's dementia (MD) or parkinsonism-dementia complex (PDC) is associated with differences in brain volume among chamoro adults. Neurology 62 (suppl 5):A344, 2004.

Kaye J, Samit P, Sudeshna A, Gorman W, Zimmerman E, Moore M, Silbert L. High signal intensity volume predicts the time to dementia among normal aging and early cognitive impairment. Neurology 62 (suppl 5):A254, 2004.

Lezak M, Howieson D, Loring D. Neuropsychological assessment; 2004.

Manczak M, Park BS, Jung Y, Reddy PH. Differential expression of oxidative phosphorylation genes in patients with Alzheimer's disease: implications for early mitochondrial dysfunction and oxidative damage. Neuromolecular Medicine 5:147-162, 2004.

Meuser T, Boise L, Morris J. Clinician beliefs and practices in dementia care: Implications for health educators. Educational Gerontology 30:491-516, 2004.

Montine K, Quinn J, Zhang J, Fessel J, Roberts L, Morrow J, Montine T. Isoprostanes and related products of lipid peroxidation in neurodegenerative diseases. Chemistry and Physics of Lipids 128:117-124, 2004.

Quinn J, Kaye J, Montine T, Stackman R. Phytochemicals in Alzheimer Disease: The Development of Clinical Trials. Archives Of Physiology And Biochemistry 42:64-73, 2004.
Quinn JF, Montine KS, Moore M, Morrow JD, Kaye JA, Montine TJ. Suppression of longitudinal increase in CSF F2-isoprostanes in Alzheimer's disease. Journal of Alzheimer's Disease 6:93-97, 2004.

Reddy P, McWeeney S, Park B, Manczak M, Gutala R, Jung J, Yau V, Searles R, Mori M, Quinn J. Gene expression profiles of transcripts in amyloid precursor protein transgenic mice: Up-regulation of mitochondrial metabolism and apoptotic genes Is an early cellular change in Alzheimer’s disease. Human Molecular Genetics 13:1225-1240, 2004.

Wijsman E, Daw E, Yu C, Payami H, Steinbart E, Nochlin D, Conlon E, Bird T, Schellenberg G. Evidence for a novel late-onset Alzheimer disease locus on chromosome 19p13.2. American Journal of Human Genetics 75:398-409, 2004.

2003

Aisen PS, Schafer KA, Grundman M, Pfeiffer E, Sano M, Davis KL, Farlow MR, Jin S, Thomas RG, Thal LJ. Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial. JAMA: The Journal of the American Medical Association 289:2819-2826, 2003. 

Camicioli R, Moore M, Kinney A, Corbridge E, Glassberg K, Kaye J. Parkinson's disease is associated with hippocampal atrophy. Movement Disorders 18:784-790, 2003. 

Clark C, Xie S, Chittams J, Ewbank D, Peskind E, Galasko D, Morris J, McKeel Jr D, Farlow M, Weitlauf S, Quinn J, Kaye J, Knopman D, Arai H, Doody R, DeCarli C, Leight S, Lee Y, Trojanoski J. Cerebrospinal fluid tau and beta-amyloid: How well do these biomarkers reflect autopsy-confirmed dementia diagnoses? Archives of Neurology 60:1696-1702, 2003. 

Grundman M, Jack Jr. C, Petersen R, Kim H, Tayloer C, Datvian M, Weiner M, DeCarli C, DeKosky S, van Dyck C, Darvesh S, Yaffe K, Kaye J, Thomas R, Thal L. Hippocampal volume is associated with memory but not non-memory cognitive performance in patients with mild cognitive impairment. Journal of Molecular Neuroscience 20:241-248, 2003. 

Hansen L, Kaye J, Dorn R, Benson H, Davies V, Clark D, Ball M. Families' experiences permitting brain autopsy for the Oregon Brain Bank in the context of the neuropathology report. Brain Aging 3:28-35, 2003. 

Howieson D, Camicioli R, Quinn J, Silbert L, Care B, Moore M, Dame A, Sexton G, Kaye J. Natural history of cognitive decline in the old old. Neurology 60:1489-1494, 2003. 

Kaye J, Moore M, Dame A, Howieson D, Quinn J, Silbert L, Zitzelberger T, Friedman D. Distinguishing features of the oldest old with elite memory function. Neurology (Suppl) 60:A79, 2003. 

Payami H, Nutt J, Gancher S, Bird T, Gonzales McNeal M, Seltzer W K, Hussey J, Lockhart P, Gwinn-Hardy K, Singleton A, Singleton A, Hardy J, Farrer M. SCA2 may present as levodopa responsive Parkinsonism. Movement Disorders 18:425-429, 2003. 

Quinn J. Vascular Dementia. Journal of the American Medical Director Association 4:S155-161, 2003. 

Quinn J, Montine T, Morrow J, Woodward WR, Kulhanek D, Eckenstein F. Inflammation and cerebral amyloidosis are disconnected in an animal model of Alzheimer's disease. J Neuroimmunol 137:32-41, 2003. 

Quinn J, Suh J, Moore M, Kaye J, Frei B. Antioxidants in Alzheimer's disease; Vitamin C delivery to a demanding brain. Journal of Alzheimer's Disease 5:309-313, 2003. 

Silbert L, Quinn J, Moore M, Corbridge E, Ball M, Murdock G, Sexton G, Kaye J. Changes in premorbid brain volume predict AD pathology. Neurology 61:487-492, 2003. 

Silbert LC, Quinn JF, Moore MM, Corbridge E, Ball MJ, Murdoch G, Sexton G, Kaye JA. Changes in premorbid brain volume predict Alzheimer's disease pathology. Neurology 61:487-492, 2003. 

Singer C, Tractenberg R, Kaye J, Schafer K, Gamst A, Grundman M, Thomas R, Thal L. A multicenter, placebo-controlled trial of melatonin for sleep disturbance in Alzheimer' disease. Sleep 26:893-901, 2003. 

Soderling S, Langeberg L, Soderling J, Davee S, Simerly R, Raber J, Schott J. Loss of WAVE-1 causes sensorimotor retardation and reduced learning and memory in mice. Proceedings of the National Academy of Sciences of USA 100:1723-1728, 2003. 

Spencer D, Spielman D, Zitzelberger T, Kaye J. Magnetic resonance spectroscopy in the "oldest old" may predict progression to dementia. Neurology 58:A402, 2003. 

Spencer D, Zitzelberger T, Spielman D, Kaye J. MRS in relation to hippocampal volume in the oldest old. Neurology 60:1194-1196, 2003. 

Stackman R, Eckenstein F, Frei B, Kulhanek D, Nowlin J, Quinn J. Prevention of age-related spatial memory deficits in a transgenic mouse model of Alzheimer's disease by chronic ginkgo biloba treatment. Experimental Neurology 184:510-520, 2003. 

Tractenberg R, Singer C, Cummings J, Thal L. The Sleep Disorders Inventory: an instrument for studies of sleep disturbance in persons with Alzheimer's disease. Journal of Sleep Research 12:331-337, 2003. 

Wild K, Cotrell V. Identifying driving impairment in Alzheimer disease:  A comparison of self and observer reports versus driving evaluation. Alzheimer Disease and Associated Disorders 17:27-34, 2003. 

Wilmot B, Sheridan B, Fife D, O'Malley J, Murdoch G, Nagalla S, Kaye J, Kramer P. Effect of apolipoprotein e genotype on differential gene expression in control and Alzheimer's disease brain. Neurology 60 (suppl 1):A455, 2003. 

Yesavage J, Friedman L, Ancoli-Israel S, Bliwise D, Singer C, Vitiello M, Monjan A, Lebowitz B. Development of diagnostic criteria for defining sleep disturbance in Alzheimer's disease. Journal of Gertiatric, Psychiatry and Neurology 16:131-139, 2003. 

2002

Colangelo V, Schurr J, Ball M, Pelaez R, Bazan N, Lukiw W. Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: Transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-Inflammatory signaling. Journal of Neuroscience Research 70:462-473, 2002. 

Erten-Lyons D, Camicioli R, Kaye J, Silbert L, Frank E, Quinn J. Lumbo-peritoneal shunt as a diagnostic aid in the management of normal pressure hydrocephalus: The Oregon Aging and Alzheimer Center experience. Canadian Journal of Neurological Sciences 29:S40, 2002. 

Friedman D, Moore M, Quinn J, Howieson D, Kaye J. Use it or lose it: A prospective evaluation of intellectual activity and the development of dementia. Neurology 58:A103, 2002. 

Haan M, Jagust W, Galasko D, Kaye J. Effect of extrapyramidal signs and lewy bodies on survival in patients with Alzheimer disease. Archives of Neurology 59:588-593, 2002. 

Hooker K, Bowman S, Coehlo D, Lim S, Kaye J, Guariglia R, Li F. Behavioral change in persons with dementia:  Relationships with mental and physical health of caregivers. Journal of Gerontology:  Psychological Sciences 57:453-460, 2002. 

Howieson D, Lezak M. Separating memory from other cognitive problems. In: (Eds.) ABaBW, ed. Handbook of Memory Disorders: John Wiley & Sons, 2002.

Howieson D, Lezak M. The neuropsychological evaluation. In: (Eds.) HaY, ed. The American Psychiatric Press Textbook of Neuropsychiatry: American Psychiatric Association, 2002.

Hussey J, Lockhart P, Seltzer W, Zbigniew K, Wszolek Z, Payami H, Hanson M, Gwinn-Hardy K, Farrer M. Accurate determination of ataxin-2 polyglutamine expansion in patients with intermediate-range repeats. Genetic Testing 6:217-220, 2002. 

Kaye J. Healthy Brain Aging. Archives of Neurology 59:1721-1723, 2002. 

Kaye J, Dame A, Moore M, Quinn J, Howieson D, Camicioli R, Sexton G. Hippocampal volume predicts dementia-free survival up to 12 years before symptom onset. Neurology 58:A400, 2002. 

Kaye J, Syms M, Thurber D, Calvert J, White S, Russell L. Exceptional survival is rarely associated with intact cognition in a rural population-based cohort. Neurobiology of Aging 23:S448, 2002. 

Kaye JA. Healthy brain aging. Archives of Neurology 59:1721-1723, 2002. 

Marquis S, Moore MM, Howieson DB, Sexton G, Payami H, Kaye JA, Camicioli R. Independent predictors of cognitive decline in healthy elderly persons. Archives of Neurology 59:601-606, 2002. 

Messecar D, Archbold P, Stewart B, Kirschling J. Home environmental modification strategies used by caregivers of elders. Research in Nursing and Health 25:357-370, 2002. 

Montine K, Montine T, Morrow J, Frei B, Milatovic D, Eckenstein F, Quinn J. Mouse cerebral prostaglandins, but not oxidative damage, change with age and are responsive to indomethacin treatment. Brain Research 930:75-82, 2002. 

Montine T, Neely M, Quinn J, Beal M, Markesbery W, Roberts L, Morrow J. Lipid peroxidation in aging brain and Alzheimer's disease. Free Radical Biology and Medicine 33:620-626, 2002. 

Montine TJ, Quinn JF, Milatovic D, Silbert LC, Dang T, Sanchez S, Terry E, Roberts LJ, 2nd, Kaye JA, Morrow JD. Peripheral F2-isoprostanes and F4-neuroprostanes are not increased in Alzheimer's disease. Annals of Neurology 52:175-179, 2002. 

Payami H, Zareparsi S, James D, Nutt J. Familial aggregation of Parkinson's disease: A comparative study of early-onset and late-onset disease. Archives of Neurology 59:848-850, 2002. 

Quinn J, Kulhanek D, Nowlin J, Murdoch G. Brain tissue expression of antioxidant enzymes in an animal model of Alzheimer's disease: Cellular specificity and changes with age. In: Society for Neuroscience Abstracts, 2002.

Quinn J, Montine T, Dang T, Rask T, Corbridge E, Moore M, Desrochers K, Coakley B, Kaye J. Rate of ventricular enlargement is the best biomarker predicting clinical progression of Alzheimer's disease over one year. Neurology 58:A142, 2002. 

Quinn J, Moore M, Benson DF, Clark CM, Doody R, Jagust W, Knopman D, Kaye JA. A videotaped CIBIC for dementia patients: validity and reliability in a simulated clinical trial. Neurology 58:433-437, 2002. 

Riviere G, Riviere K, Smith K. Molecular and immunologic evidence of oral treponema in human brain and their association with Alzheimer's disease. Oral Microbiology and Immunology 17:113-118, 2002. 

Salat DH, Kaye JA, Janowsky JS. Greater orbital prefrontal volume selectively predicts worse working memory performance in older adults. Cereb Cortex 12:494-505, 2002. 

Singer C, Tractenberg R, Kaye J, Schafer K, Gamst A, Grundman M, Thomas R, Thal L. ADCS clinical trial of melatonin for the sleep disturbance of Alzheimer's:  Case report of an unusual sleep/wake cycle and response to melatonin. American Journal of  Geriatric Psychiatry 10:92, 2002. 

Zareparsi S, Camicioli R, Sexton G, Bird T, Swanson P, Kaye J, Nutt J, Payami H. Age at onset of Parkinson disease and apolipoprotein E genotypes. American Journal of Medical Genetics 107:156-161, 2002. 

Zareparsi S, James D, Kaye J, Bird T, Schellenberg G, Payami H. HLA-A2 homozygosity but not heterozygosity is associated with Alzheimer's disease. Neurology 58:973-975, 2002.