OHSU

NIA-Funded Oregon Alzheimer's Disease Center

The Oregon Alzheimer Disease Center (OADC) is the core program of the Layton Aging & Alzheimer’s Disease Center. It was established in 1990 with funding from the National institute on Aging, part of the National Institutes of Health. The OADC builds upon talents and resources of Oregon and the Pacific Northwest to sustain strong research programs in brain aging and dementia.

The OADC promotes interactive, multidisciplinary research among the scientific community. A primary focus of the OADC is on studies of preclinical or incipient dementia, as well as early dementia.  Well-characterized patients, clinical, MRI, genetic and family history data, and tissues and biological specimens are made available to investigators and research groups.

The OADC recruits and follows research volunteers of several kinds. Our research cohorts include:

  1. Healthy elderly at high risk of developing dementia, emphasizing those older than 85 years of age 
  2. Persons with mild cognitive impairment (MCI) or early AD 
  3. Subjects reflecting social and ethnic diversity (African American and rural populations) 
  4. Persons with less common dementias (e.g. dementia with Lewy bodies and frontotemporal dementia) for collaborative study with other AD centers.

In addition, the OADC serves to provide key knowledge to the professional and lay community as the expert source in Oregon for information and education in brain aging and Alzheimer’s disease (AD). Through the OADCs Cores, the OADC has fostered the creation of a living laboratory and inspired a community of learning around it. 

To find out more about the Oregon Alzheimer’s Disease Center’s research and education programs, follow the links for the five Cores in the menu to the left.