Phillips TJ, Mootz JR, Reed C. Identification of Treatment Targets in a Genetic Mouse Model of Voluntary Methamphetamine Drinking. Int Rev Neurobiol. 2016;126:39-85. doi: 10.1016/bs.irn.2016.02.001. Epub 2016 Mar 7. PMID: 27055611

Ellis C, Hoffman W, Jaehnert S, Plagge J, Loftis JM, Schwartz D, Huckans MEveryday problems with executive dysfunction and impulsivity in adults recovering from methamphetamine addiction. Addict Disord Their Treat. 2016 Mar;15(1):1-5. PMID: 27034621

Shi X, Walter NA, Harkness JH, Neve KA, Williams RW, Lu L, Belknap JK, Eshleman AJ, Phillips TJ, Janowsky AGenetic Polymorphisms Affect Mouse and Human Trace Amine-Associated Receptor 1 Function. PLoS One. 2016 Mar 31;11(3):e0152581. doi: 10.1371/journal.pone.0152581. eCollection 2016. PMID: 27031617

Janowsky A, Tosh DK, Eshleman AJ, Jacobson KA. Rigid Adenine Nucleoside Derivatives as Novel Modulators of the Human Sodium Symporters for Dopamine and Norepinephrine. J Pharmacol Exp Ther. 2016 Apr;357(1):24-35. doi: 10.1124/jpet.115.229666. Epub 2016 Jan 26. PMID: 26813929

Lominac KD, Quadir SG, Barrett HM, McKenna CL, Schwartz LM, Ruiz PN, Wroten MG, Campbell RR, Miller BW, Holloway JJ, Travis KO, Rajasekar G, Maliniak D, Thompson AB, Urman LE, Kippin TE, Phillips TJ, Szumlinski KK. Prefrontal glutamate correlates of methamphetamine sensitization and preference. Eur J Neurosci. 2016 Mar;43(5):689-702. doi: 10.1111/ejn.13159. Epub 2016 Feb 22. PMID: 26742098

Alanis-Hirsch K, Croff R, Ford JH 2nd, Johnson K, Chalk M, Schmidt L, McCarty DExtended-Release Naltrexone: A Qualitative Analysis of Barriers to Routine Use. J Subst Abuse Treat. 2016 Mar;62:68-73. doi: 10.1016/j.jsat.2015.10.003. Epub 2015 Nov 6. PMID: 26654934


Huckans M, Fuller B, Wheaton V, Jaehnert S, Ellis C, Kolessar M, Kriz D, Anderson JR, Berggren K, Olavarria H, Sasaki AW, Chang M, Flora KD, Loftis JMA longitudinal study evaluating the effects of interferon-alpha therapy on cognitive and psychiatric function in adults with chronic hepatitis C. J Psychosom Res. 2015 Feb;78(2):184-92. doi: 10.1016/j.jpsychores.2014.07.020. Epub 2014 Aug 7. PMID: 25219976 

Rieckmann T, Abraham A, Zwick J, Rasplica C, McCarty DA Longitudinal Study of State Strategies and Policies to Accelerate Evidence-Based Practices in the Context of Systems Transformation. Health Serv Res. 2015 Aug;50(4):1125-45. doi: 10.1111/1475-6773.12273. Epub 2014 Dec 23.PMID: 25532616

Phillips TJ, Reed C, Pastor R. Preclinical evidence implicating corticotropin-releasing factor signaling in ethanol consumption and neuroadaptation. Genes Brain Behav. 2015 Jan;14(1):98-135. doi: 10.1111/gbb.12189. Review.PMID: 25565358

Zheng CL, Wilmot B, Walter NA, Oberbeck D, Kawane S, Searles RP, McWeeney SK, Hitzemann R. Splicing landscape of the eight collaborative cross founder strains. BMC Genomics. 2015 Feb 5;16:52. doi: 10.1186/s12864-015-1267-0.PMID: 25652416 

Harkness JH, Shi X, Janowsky A, Phillips TJTrace Amine-Associated Receptor 1 Regulation of Methamphetamine Intake and Related Traits. Neuropsychopharmacology. 2015 Aug;40(9):2175-84. doi: 10.1038/npp.2015.61. Epub 2015 Mar 5.PMID: 25740289 

Penmatsa A, Wang KH, Gouaux E. X-ray structures of Drosophila dopamine transporter in complex with nisoxetine and reboxetine. Nat Struct Mol Biol. 2015 Jun;22(6):506-8. doi: 10.1038/nsmb.3029. Epub 2015 May 11.PMID: 25961798

Wang KH, Penmatsa A, Gouaux E. Neurotransmitter and psychostimulant recognition by the dopamine transporter. Nature. 2015 May 21;521(7552):322-7. doi: 10.1038/nature14431. Epub 2015 May 11.PMID: 25970245 

Gantz SC, Robinson BG, Buck DC, Bunzow JR, Neve RL, Williams JT, Neve KA. Distinct regulation of dopamine D2S and D2L autoreceptor signaling by calcium. Elife. 2015 Aug 26;4. doi: 10.7554/eLife.09358.PMID: 26308580 

Pflibsen L, Stang KA, Sconce MD, Wilson VB, Hood RL, Meshul CK, Mitchell SH. Executive function deficits and glutamatergic protein alterations in a progressive 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. J Neurosci Res. 2015 Dec;93(12):1849-64. doi: 10.1002/jnr.23638. Epub 2015 Aug 31.PMID: 26332770

Ozburn AR, Janowsky AJ, Crabbe JC. Commonalities and Distinctions Among Mechanisms of Addiction to Alcohol and Other Drugs. Alcohol Clin Exp Res. 2015 Oct;39(10):1863-77. doi: 10.1111/acer.12810. Review.PMID: 26431116


Abraham AD, Neve KA, Lattal KM. Dopamine and extinction: a convergence of theory with fear and reward circuitry. Neurobiol Learn Mem. 2014 Feb;108:65-77. PubMed PMID: 24269353;PubMed Central PMCID: PMC3927738.

Anacker AM, Ahern TH, Hostetler CM, Dufour BD, Smith ML, Cocking DL, Li J, Young LJ, Loftis JM, Ryabinin AE. Drinking alcohol has sex-dependent effects on pair bond formation in prairie voles. Proc Natl Acad Sci U S A. 2014 Apr 22;111(16):6052-7. PubMed PMID: 24711424

Downey LA, Loftis JM. Altered energy production, lowered antioxidant potential, and inflammatory processes mediate CNS damage associated with abuse of the psychostimulants MDMA and methamphetamine. Eur J Pharmacol. 2014 Mar 15;727:125-9. PubMed PMID: 24485894;PubMed Central PMCID: PMC3970781.

Eastwood EC, Phillips TJ. Morphine intake and the effects of naltrexone and buprenorphine on the acquisition of methamphetamine intake. Genes Brain Behav. 2014 Feb;13(2):226-35. PubMed PMID: 24152140;PubMed Central PMCID: PMC3976242

Eastwood EC, Phillips TJ. Opioid sensitivity in mice selectively bred to consume or not consume methamphetamine. Addict Biol. 2014 May;19(3):370-9. PubMed PMID: 23145527;PubMed Central PMCID: PMC3796126.

Eshleman AJ, Forster MJ, Wolfrum KM, Johnson RA, Janowsky A, Gatch MB. Behavioral and neurochemical pharmacology of six psychoactive substituted phenethylamines: mouse locomotion, rat drug discrimination and in vitro receptor and transporter binding and function. Psychopharmacology (Berl). 2014 Mar;231(5):875-88. PubMed PMID: 24142203;PubMed Central PMCID: PMC3945162.

Huckans M, Fuller BE, Olavarria H, Sasaki AW, Chang M, Flora KD, Kolessar M, Kriz D, Anderson JR, Vandenbark AA, Loftis JM. Multi-analyte profile analysis of plasma immune proteins: altered expression of peripheral immune factors is associated with neuropsychiatric symptom severity in adults with and without chronic hepatitis C virus infection. Brain Behav. 2014 Mar;4(2):123-42. PubMed PMID: 24683507;PubMed Central PMCID: PMC3967530. 

Janowsky A, Eshleman AJ, Johnson RA, Wolfrum KM, Hinrichs DJ, Yang J, Zabriskie TM, Smilkstein MJ, Riscoe MK. Mefloquine and psychotomimetics share neurotransmitter receptor and transporter interactions in vitro. Psychopharmacology (Berl). 2014 Feb 2;PubMed PMID: 24488404;NIHMSID: 589475.

Raybuck JD, Lattal KM. Differential effects of dorsal hippocampal inactivation on expression of recent and remote drug and fear memory. Neurosci Lett. 2014 Mar 28;569C:1-5. PubMed PMID: 24686177;NIHMSID: 580903.

Ye T, Pozos H, Phillips TJ, Izquierdo A. Long-term effects of exposure to methamphetamine in adolescent rats. Drug Alcohol Depend. 2014 May 1;138:17-23. PubMed PMID: 24629630;NIHMSID: 571131.


Antonio T, Childers SR, Rothman RB, Dersch CM, King C, Kuehne M, Bornmann WG, Eshleman AJ, Janowsky A, Simon ER, Reith ME, Alper K. Effect of Iboga alkaloids on µ- opioid receptor-coupled G protein activation. PLoS One. 2013;8(10):e77262. PubMed PMID: 24204784;PubMed Central PMCID: PMC3818563.

Belknap JK, McWeeney S, Reed C, Burkhart-Kasch S, McKinnon CS, Li N, Baba H, Scibelli AC, Hitzemann R, Phillips TJ. Genetic factors involved in risk for methamphetamine intake and sensitization. Mamm Genome. 2013 Dec;24(11-12):446-58. PubMed PMID: 24217691;PubMed Central PMCID: PMC3880562. 

Gubner NR, Reed C, McKinnon CS, Phillips TJ. Unique genetic factors influence sensitivity to the rewarding and aversive effects of methamphetamine versus cocaine. Behav Brain Res. 2013 Nov 1;256:420-7. PubMed PMID: 23994231;PubMed Central PMCID: PMC3907175.

Eastwood, E.C. and Phillips, T.J. (2013) Opioid sensitivity in mice selectively bred to consume or not consume methamphetamine. Addiction Biol, in press.  PMID: 23145527;NIHMSID: 463238;PMCID: in progress.

Ellis, C., Jaehnert, S., Plagge, J., Loftis, J.M., Schwartz, D., Hoffman, W., &Huckans, M.  Everyday problems related to executive dysfunction and impulsivity in adults recovering from methamphetamine addiction.  Poster session presented at the 41st annual meeting of the International Neuropsychological Society, Waikoloa, HI, February 6-9, 2013.

Eshleman AJ, Wolfrum KM, Hatfield MG, Johnson RA, Murphy KV, Janowsky A. Substituted methcathinones differ in transporter and receptor interactions. Biochem Pharmacol. 2013 Jun 15;85(12):1803-15. PubMed PMID: 23583454;PubMed Central PMCID: PMC3692398. 

Harkness, J.H., Hitzemann, R.J., Edmunds, S. and  Phillips, T.J. (2013) Effects of sodium butyrate on methamphetamine-sensitized locomotor activity. Behav Brain Res 239:139-147. PMCID: PMC3546510

Hilsabeck, R. &Huckans, M. (2013). HIV and Hepatitis C. In S.S. Bush (Ed.), Neuropsychological Practice with Veterans.  New York, NY:  Springer Publishing Co.

Huckans, M., &Hilsabeck, R.C. (2013). Substance use disorders. In S.S. Bush (Ed.), Neuropsychological Practice with Veterans. New York, NY: Springer Publishing Co.

Huckans, M., Hutson, L., Twamley, E., Jak, A., Kaye, J. &Storzbach, D. (2013). Efficacy of cognitive rehabilitation therapies for mild cognitive impairment (MCI) in older adults: Working toward a theoretical model and evidence-based interventions.  Neuropsychology Review, 23(1), pp. 63-80.  PMC submission In Process.

Jaehnert, S.M., Ellis, C., Prince, C., Wheaton, V., Loftis, J., Fuller, B., Schwartz, D., Hoffman, W., &Huckans, M. (2013, October).  A longitudinal study evaluating neuropsychological function across the first two months of remission from methamphetamine dependence. Poster session to be presented at the annual meeting of the National Academy of Neuropsychology, San Diego, CA.

Lattal, K.M. &Wood, M.A. (2013). Epigenetics and persistent memory: Implications for reconsolidation and silent extinction beyond the zero.  Nature Neuroscience, 16, 124-129.  PMC Journal: In progress

Loftis, J.M., Wilhelm, C.J., Huckans, M.  Effect of epigallocatechin gallate (EGCG) supplementation in schizophrenia and bipolar disorder: an 8-week, randomized, double-blind, placebo-controlled study. Therapeutic Advances in Psychopharmacology. 2013, 3(1): 21-27.

Loftis, J.M., Wilhelm, C.J., Vandenbark, A.A., Huckans, M. Partial MHC/Neuroantigen Peptide Constructs: A Potential Neuroimmune-Based Treatment for Methamphetamine Addiction. PLoS One. 2013;8(2):e56306. PMCID: PMC3584080

** The Oregon Health &Science University (OHSU) School of Medicine (SoM) featured this paper as SoM Paper of the Month for April 2013.

Loftis JM, Huckans M. Substance use disorders: psychoneuroimmunological mechanisms and new targets for therapy. Pharmacol Ther. 2013 Aug;139(2):289-300. PubMed PMID: 23631821;PubMed Central PMCID: PMC3725980. 

McCarty D. Parity: an ongoing challenge and research opportunity. Am J Psychiatry. 2013 Feb 1;170(2):140-2. PubMed PMID: 23377632;PubMed Central PMCID: PMC3951725. 

Moschak, T. M., Stang, K. A., &Mitchell, S. H. (2013 in press). Mice bred for severity of acute alcohol withdrawal respond differently in a Go/No-go task. Alcoholism: Clinical &Experimental Research. PMCID: In Progress

Neve KA, Ford CP, Buck DC, Grandy DK, Neve RL, Phillips TJ. Normalizing dopamine D2 receptor-mediated responses in D2 null mutant mice by virus-mediated receptor restoration: Comparing D2<sub>L</sub>and D2<sub>S</sub>. Neuroscience. 2013 Jun 27;248C:479-487. PubMed PMID: 23811070;PubMed Central PMCID: PMC3858482. 

Olsen RH, Allen CN, Derkach VA, Phillips TJ, Belknap JK, Raber J. Impaired memory and reduced sensitivity to the circadian period lengthening effects of methamphetamine in mice selected for high methamphetamine consumption. Behav Brain Res. 2013 Nov 1;256:197-204. PubMed PMID: 23954232;PubMed Central PMCID: PMC3815974. 

Raybuck, J.D., McCleery, E.J., Cunningham, C.L., Wood, M.A., &Lattal, K.M. (2013). The histone deacetylase inhibitor sodium butyrate modulates acquisition and extinction of cocaine-induced conditioned place preference. Pharmacology, Biochemistry and Behavior (in press).  PMC Journal: In progress.

Sakamoto M, Woods SP, Kolessar M, Kriz D, Anderson JR, Olavarria H, Sasaki AW, Chang M, Flora KD, Loftis JM, Huckans M. Protective effects of higher cognitive reserve for neuropsychological and daily functioning among individuals infected with hepatitis C. J Neurovirol. 2013 Oct;19(5):442-51. PubMed PMID: 24018902;PubMed Central PMCID: PMC3920983. 

Tipps ME, Raybuck JD, Lattal KM. Substance abuse, memory, and post-traumatic stress disorder. Neurobiol Learn Mem. 2013 Dec 15;PubMed PMID: 24345414;NIHMSID: 550376.

Wilhelm CJ, Choi D, Huckans M, Manthe L, Loftis JM. Adipocytokine signaling is altered in Flinders sensitive line rats, and adiponectin correlates in humans with some symptoms of depression. Pharmacol Biochem Behav. 2013 Jan;103(3):643-51. doi: 10.1016/j.pbb.2012.11.001. Epub 2012 Nov 12. Pending PMC Submission.


Cashman JR, Okolotowicz K, Cerny M, Johnson R, Janowsky A, Azar MR.  Substituted heteroaromatic compounds: effect on nicotine self-administration in rats.  Psychopharmacology (Berl). 221:637-48 (2012)

Eshleman, A.J. Wolfrum, K.M., Hatfield, M.G., Johnson, R.A., Murphy K.V., Janowsky, A Substituted methcathinones differ in transporter and receptor interactions. Biochemical Pharmacology (in press). PMC Journal –In Process.

Harkness, J.H., Eastwood, E., Loftis, J.M., Raber, J., Phillips, T.J. Effects of prenatal methamphetamine exposure on adult cognitive performance (poster presentation). Society for Neuroscience, New Orleans, LA, October 13-17, 2012.

Huckans, M., Buenafe, A., Huan, J., Vandenbark, A.A., Loftis, J.M. Methamphetamine addiction is associated with increased T-cell immunoreactivity and neuropsychiatric impairment. 19th Psychoneuroimmunology Research Society meeting, San Diego, CA, June 7-9, 2012. [Brain, Behavior &Immunity 26, Suppl.1:S25-S26].

Javor, S., Janowsky, A., Johnson R.A., Wolfrum, K., Tadayoni-Rebek, M., and Rebek  J., Jr. Formylated Polyamines as Peptidomimetics Bioorg Med Chem Lett. 22:6580-2 (2012)

Keith D.J., Eshleman, A.J., Janowsky A. Melittin initiates dopamine transporter internalization and recycling in transfected HEK-293 cells. Eur. J. Pharmacol 690:13-21 (2012) PMCID:  PMC3632331

Loftis, J.M. and Huckans, M.  Substance use disorders: Psychoneuroimmunological mechanisms and new targets for therapy Pharmacology &Therapeutics (invited manuscript;in press).

Loftis, J.M., Huckans, M., Woods, S.P. Substance abuse and infectious disease (invited book chapter). To be published in Neuropsychological Aspects of Substance Use Disorders: Evidence-Based Perspectives, Daniel N. Allen &Steven Paul Woods (Eds.). New York, NY: Oxford University Press. 2012.10.012. Epub 2012 Nov 21. PMC submission In Process.

Loftis, J.M., Wilhelm, C.J., Vandenbark, A.A., Huckans, M. Partial MHC/neuroantigen peptide improves cognitive function following methamphetamine exposure (poster presentation). 22nd Neuropharmacology Conference. Official Satellite to the 2012 Meeting of the Society for Neuroscience,  New Orleans, LA, October 11-12, 2012.

Matthews, A. M., Wilson, V. B., Mitchell, S. H., &Hauser, P. (in press) Smoking characteristics of Veterans enrolled in a large multicenter study of bipolar disorder. Federal Practitioner.

Mitchell, S. H. &Wilson, V. B. (2012).  Differences in delay discounting between smokers and nonsmokers remain when both rewards are delayed.  Psychopharmacology, 219, 549–562. PMID: 21983917;PMCID: In Progress

Moschak, T. M., &Mitchell, S. H. (2012). Acute ethanol administration and reinforcer magnitude reduction both reduce responding and increase response latency in a Go/No-Go task.  Alcoholism: Clinical and Experimental Research, 36, 1803-1810. doi: 10.1111/j.1530-0277.2012.01789.x. PMCID: PMC3396725

Moschak, T.M., Stang, K.A., Phillips, T.J. and Mitchell, S.H. (2012) Behavioral inhibition in mice bred for high vs. low levels of methamphetamine consumption or sensitization. Psychopharmacology 222:353-365. PMCID: PMC3383918

Shabani, S., McKinnon, C.S., Cunningham, C.L. and Phillips, T.J. (2012) Profound reduction in sensitivity to the aversive effects of methamphetamine in mice bred for high methamphetamine intake. Neuropharmacology 62:1134-1141. PMCID: PMC3297479

Shabani, S., Dobbs, L.K., Ford, M.M., Finn, D.A. and Phillips, T.J. (2012) A genetic animal model of differential sensitivity to methamphetamine reinforcement. Neuropharmacology 62:2168-2176. PMCID: PMC3320769

Wilhelm, C. J., &Mitchell, S. H. (2012). Acute ethanol does not always affect delay discounting in rats selected to prefer or avoid ethanol.  Alcohol and Alcoholism, 47, 518-24. PMID: 22645038;PMCID: PMC3500854

Wilhelm CJ, Murphy-Crews A, Menasco DJ, Huckans MS, Loftis JM. Corticotropin releasing factor-1 receptor antagonism alters the biochemical, but not behavioral effects of repeated interleukin-1β administration. Neuropharmacology. 2012 Jan;62(1):313-21. PMCID: PMC3196278.

Yankelevitz, R. L., Mitchell, S. H. &Zhang, Y. (2012). Gender differences in factors associated with alcohol drinking: Delay discounting and perception of others' drinking.  Drug and Alcohol Dependence, 123, 273-6. PMID: 22154359;PMCID: In Progress

Wang GJ, Smith L, Volkow ND, Telang F, Logan J, Tomasi D, Wong CT, Hoffman W, Jayne M, Alia-Klein N, Thanos P, Fowler JS. (2012) Decreased dopamine activity predicts relapse in methamphetamine abusers. Psychiatry. 17(9): 918-25.  PMC3261322


Booth RE, Campbell BK, Mikulich-Gilbertson SK, Tilotson CJ, Choi D, Robinson J, Mandler R, Calsyn D, Jenkins L, Thomson L, Dempsey C, Liepman M, McCarty D. (2011). Reducing HIV-related risk behaviors among injection drug users in residential detoxification. AIDS and Behavior. 15(1):30-44. PMC3023839

Fei, SS, Wilmarth, PA, Hitzemann, RJ, McWeeney, SK, Belknap, JK and David, LL. (2011). Protein database and quantitative analysis considerations when integrating genetics and proteomics to compare mouse strains. J Proteome Res 10:2905-2912. PMC3128464

Hilsabeck, R. & Huckans, M. (in press). HIV and Hepatitis C. In S.S. Bush (Ed.), Neuropsychological Practice with Veterans. New York, NY: Springer Publishing Co.

Huckans, M., & Hilsabeck, R. (in press). Substance Use Disorders. In S.S. Bush (Ed.), Neuropsychological Practice with Veterans.  New York, NY: Springer Publishing Co.

Iancu, OD, Darakjian, P, Walter, N, Malmanger, B, Oberbeck, D, Belknap, JK, McWeeney, S and Hitzemann, R. (2011). Genetic diversity and striatal gene networks: Focus on the heterogeneous stock-collaborative cross mouse. BMC Genomics 11:585.PMC3091732

Keith, D.J. Eshleman, AJ and Janowsky A. (2011).  Melittin stimulates fatty acid release through non-phospholipase-mediated mechanisms and interacts with the dopamine transporter and other membrane-spanning proteins. Europ. J. Pharmacol. 650(2-3):501-10.PMC3125126

Loftis JM, Choi D, Hoffman W, Huckans MS. (2010). Methamphetamine causes persistent immune dysregulation: a cross-species, translational report. Neurotox Res. Jul;20(1):59-68. Epub. PMC3081419

Loftis JM, Huckans M. (2011). Cognitive enhancement in combination with 'brain repair' may be optimal for the treatment of stimulant addiction. Addiction. 106(5):1021-2. doi: 10.1111/j.1360-0443.2010.03354.x. Epub. [Letter to the Editor]

McFarland BHMcCarty D, Kovas AE (editors). Medicaid and treatment for people with substance abuse problems.  Hauppauge, NY: Nova Science Publishers, Inc., in press.

Nair, HK, Hain, H, Quock, RM, Philip, VM, Chesler, EJ, Belknap, JK and Lariviere, WR. (2011). Genomic loci and candidate genes underlying inflammatory nociception.  Pain 152:599-606. PMC3039031

Piper BJ, Acevedo SF, Kochugina GK, Butler RW, Corbett SM, Honeycutt EB, Craytor MJ, Raber J. (2011). Abnormalities in parentally rated executive function in methamphetamine/polysubstance exposed children. Pharmacology, Biochemistry and Behavior 98: 432-439. PMC3069661

Scibelli AC, McKinnon CS, Reed C, Burkhart-Kasch S, Li N, Baba H, Wheeler JM, Phillips TJ. (2011). Selective breeding for magnitude of methamphetamine-induced sensitization alters methamphetamine consumption. Psychopharmacology (Berl) 214(4):791-804. PMC3320759

Shabani S, McKinnon CS, Reed C, Cunningham CL, Phillips TJ. (2011). Sensitivity to rewarding or aversive effects of methamphetamine determines methamphetamine intake.Genes Brain Behav. 10(6):625-36. PMC3320762


Campbell BK, Tillotson CJ, Choi D, Bryant K, DiCenzo J, Provost SE, Zammarelli L, Booth RE, McCarty D. (2010). Predicting outpatient treatment entry following detoxification for injection drug use: It’s not just the patient, it’s the program. Journal of Substance Abuse Treatment. 38 (Suppl 1) S87-S96. PMC2847860

Crabbe, J.C. and Phillips, T.J. (2010). Genetic animal models. In: K.J. Sher (Ed.), Handbook of Substance Use and Dependence, Oxford University Press, in press. 

Cservenka A, Spangler E, Cote DM, Ryabinin AE. (2010). Postnatal developmental profile of urocortin 1 and cocaine- and amphetamine-regulated transcript in the perioculomotor region of C57BL/6J mice. Brain Res. 1319:33-43. PMC2826606

Gubner, N.R., Wilhelm, C.J., Phillips, T.J. and Mitchell, S.H. (2010). Strain differences in behavioral inhibition in a go/no-go task demonstrated using 15 inbred mouse strains. Alcohol Clin Exp Res 34:1353-1362. [This paper describes work that assisted in the development of a test of behavioral inhibition in mice, subsequently used for research in the MARC]PMC3336215

Huckans, M., Mitchell, A., Pavawalla, S., Morasco, B.J., Ruimy, S., Loftis, J.M., Rifai, M.A., & Hauser, P. (2010). The influence of antiviral therapy on psychiatric symptoms among hepatitis C patients with schizophrenia. Antiviral Therapy, 15(1), pp. 111-9. PMC2998439

Huckans, M., Mitchell, A., Ruimy, S., Loftis, J., & Hauser, P. (2010). Antiviral therapy completion and response rates among hepatitis C patients with and without schizophrenia. Schizophrenia Bulletin, 36(1), pp.165-72. PMC2800135  

Huckans, M., Pavawalla, P., Demadura, T., Kolessar, M., Seelye, A., Twamley, E., & Storzbach, D. (2010). A pilot study examining effects of group-based cognitive strategy training treatment on self-reported cognitive problems, psychiatric symptoms, functioning, and compensatory strategy use in OIF/OEF combat veterans with persistent mild cognitive disorder and history of traumatic brain injury. Journal of Rehabilitation Research and Development, 47(1), pp. 43-60. (free full text @ journal site)

Loftis, J.M., Huckans, M., Morasco, B.J. (2010). Neuroimmune mechanisms of cytokine-induced depression: current theories and novel treatment strategies. Neurobiology of Disease, 37(3):519-33. PMC2995293

Michaelides M, Pascau J, Gispert JD, Delis F, Grandy DK, Wang GJ, Desco M, Rubinstein M, Volkow ND, Thanos PK. (2010). Dopamine D4 receptors modulate brain metabolic activity in the prefrontal cortex and cerebellum at rest and in response to methylphenidate. Eur J Neurosci. 32(4):668-76. PMC2938021

Piper BJ, Acevedo SF, Craytor MJ, Murray PW, Raber J. (2010). The use and validation of the spatial navigation Memory Island test in primary school children. Behav Brain Res. 210(2):257-62. PMC2874075

Phillips, T.J., Pastor, R., Scibelli, A.C., Reed, C. and Tarragon, E. (2010). Behavioral sensitization to addictive drugs: Clinical relevance and methodological aspects. In: J. Raber (Ed.), Animal Models of Behavioral Analysis, Humana Press.

Schwartz, D.L., Mitchell, A.D., Lahna, D.L., Luber, H.S., Huckans, M.S., Mitchell, S.H., Hoffman, W.F. (2010). Global and local morphometric differences in recently abstinent methamphetamine-dependent individuals. Neuroimage 50, 1392-1401. PMC3478236

Shabani S, Foster R, Gubner N, Phillips TJ, Mark GP. (2010). Muscarinic type 2 receptors in the lateral dorsal tegmental area modulate cocaine and food seeking behavior in rats.Neuroscience 170(2):559-69. PMC2936824

Thanos PK, Habibi R, Michaelides M, Patel UB, Suchland K, Anderson BJ, Robinson JK, Wang GJ, Grandy DK, Volkow ND. (2010). Dopamine D4 receptor (D4R) deletion in mice does not affect operant responding for food or cocaine. Behav Brain Res. 207(2):508-11. PMC2815086

Thanos PK, Bermeo C, Rubinstein M, Suchland KL, Wang GJ, Grandy DK, Volkow ND. (2010). Conditioned place preference and locomotor activity in response to methylphenidate, amphetamine and cocaine in mice lacking dopamine D4 receptors. J Psychopharmacol. 24(6):897-904. PMC2878389


Fuller, B.E., Loftis, J.M., et al. (2009). Psychiatric and substance use disorders comorbidities in veterans with hepatitis C virus and HIV coinfection. Curr.Opin.Psychiatry 22(4):401-408. PMID: 19436202 [PMC in process]

Fussell HE, Lewy CS, McFarland BH. (2009). Evaluating and training substance abuse counselors: a pilot study assessing standardized patients as authentic clients. Substance Abuse 30(1): 47-60. PMC2668660

Huckans, M., Seelye, A., Parcel, T., Mull, L., Woodhouse, J., Bjornson, D., Loftis, J., Morasco, B., Fuller, B., Sasaki, A., Storzbach, D., & Hauser, P. (2009). The cognitive effects of hepatitis C in the presence and absence of a history of substance use disorder.JINS, 15(1), 69-82. PMC2990957

Lan H, Liu Y, Bell MI, Gurevich VV, Neve KA. (2009). A dopamine D2 receptor mutant capable of G protein-mediated signaling but deficient in arrestin binding. Molecular Pharmacology 73(3): 113-23. PMC2606918

Lan H, Teeter MM, Gurevich VV, Neve KA. (2009). An intracellular loop 2 amino acid residue determines differential binding of arrestin to the dopamine D2 and D3 receptors. Molecular Pharmacology 75(1): 19-26. PMC2606909

Spangler E, Cote DM, Anacker AM, Mark GPRyabinin AE. (2009). Differential sensitivity of the perioculomotor urocortin-containing neurons to ethanol, psychostimulants and stress in mice and rats. Neuroscience 160(1): 115-25. PMC2668734

Wheeler J.M., Reed C., Burkhart-Kasch S., Li N., Cunningham C.L.Janowsky A., Franken F.H., Wiren K.M., Hashimoto J.G., Scibelli A.C., Phillips T.J. (2009). Genetically correlated effects of selective breeding for high and low methamphetamine consumption.Genes Brain Behavior 8:758-771. PMC2783502


Dobbs, L.K. & Mark, G.P. (2008). Comparison of systemic and local methamphetamine treatment on acetylcholine and dopamine levels in the ventral tegmental area in the mouse.  Neuroscience 156(3):700-11. PMC2644326

Dobbs, L.K. & Mark, G.P. (2008). Effect of systemic and intra-tegmental methamphetamine on acetylcholine and dopamine levels in the ventral tegmental area in the mouse.  International Behavioral Neuroscience Society Abstracts.

Helms CM, Gubner NR, Wilhelm CJ, Mitchell SH, Grandy DK. (2008). D4 receptor deficiency in mice has limited effects on impulsivity and novelty seeking. Pharmacol Biochem Behav. 90(3):387-93. PMC2603181

Hitzemann R, Malmanger B, Belknap J, Darakjian P, McWeeney S. (2008). Short-term selective breeding for high and low prepulse inhibition of the acoustic startle response; pharmacological characterization and QTL mapping in the selected lines. Pharmacology, Biochemistry, and Behavior 90(4): 525-33. PMC2591930

Hoffman, W.F., Schwartz, D.L., Huckans, M.S., Meiri, G., McFarland, B.H., Stevens, A.A., Mitchell, S.H. (2008). Cortical Activation during Delay Discounting in Abstinent Methamphetamine Dependent Individuals. Psychopharmacology 201(2):183-93. PMC2835463

Jaworski, J.N., Hansen, S.T., Kuhar, M.J. & Mark, G.P. (2008). Injection of CART (Cocaine- and Amphetamine- Regulated Transcript) peptide into the nucleus accumbens inhibits cocaine self-administration in rats. Behavioral Brain Research 191(2): 266-271. PMC2497435

Kelly, M.A., Low, M.J., Rubinstein, M., Phillips, T.J. (2008). Role of dopamine D1-like receptors in methamphetamine locomotor responses of D2 receptor knockout mice. Genes Brain Behavior 7:568-57. PMC2741405

Lattal, K.M. & Stafford, J.M. (2008).  What does it take to demonstrate memory erasure? Theoretical comment on Norrholm et al. Behavioral Neuroscience 122:1186-1190. PMC2559954

Liu Y, Buck DC, Neve KA. (2008). Novel interaction of the dopamine D2 receptor and the Ca2+ binding protein S100B: role in D2 receptor function. Molecular Pharmacology 74(2): 371-8. PMC2574776

Loftis, J.M., Huckans, M. Ruimy, S., Hinrichs, D., & Hauser, P. (2008). Depressive symptoms in patients with chronic hepatitis C are correlated with elevated plasma levels of interleukin-1beta and tumor necrosis factor-alpha. Neuroscience Letters, 430(3), 264-268. PMC2342938

Meltzer, P.C., Kryatova, O., Pham-Huu, D.P., Donovan, P., Janowsky, A. (2008). The synthesis of bivalent 2β-carbomethoxy-3β-(3,4-dichlorophenyl)-8-heterobicyclo[3.2.1]octanes as probes for proximal binding sites on the dopamine and serotonin transporters.  Bioorganic & Medicinal Chemistry 16:1832-41. PMC2323586

Phillips, T.J., Kamens, H.M., Wheeler, J. (2008). Behavioral genetic contributions to the study of addiction-related amphetamine effects. Neuroscience and Biobehavioral Reviews 32:707-759. PMC2360482

Scibelli, A.C., McKinnon, C.S., Burkhart-Kasch, S., Li, N., Reed, C., Phillips, T.J. (2008). Mice selectively bred for low and high methamphetamine-induced sensitization differ in oral consumption of methamphetamine. International Behavioural and Neural Genetics Society Abstracts.

Snyder K.S., Dobscha S.K., Hoffman W.F., Delorit M., Ganzini L. (2008). Clinical Outcomes of Integrated Psychiatric and General Medical Care. Community Mental Health Journal 44:147-154. PMID: 18071900

Wheeler, J.M., Reed, C., Phillips, T.J. (2008). Methamphetamine metabolism in lines of mice selectively bred for high or low methamphetamine consumption. International Behavioural and Neural Genetics Society Abstracts.

Wheeler, J.M., Reed, C., Phillips, T.J. (2008). Mice bred for high methamphetamine consumption exhibit greater methamphetamine conditioned place preference compared to mice bred for low methamphetamine consumption. Society for Neuroscience Abstracts on-line.

Wilhelm, C.J., Johnson R.A., Eshleman, A.J., and Janowsky, A. (2008). Lobeline effects on tonic and methamphetamine-induced dopamine release.  Biochem. Pharmacol. 75:1411-5. PMC2435375


Acevedo, S.F., de Esch, I.J.P., Raber, J. (2007). Sex- and histamine-dependent long-term cognitive effects of methamphetamine exposure. Neuropsychopharmacology 32:665-672. PMID: 16710318; Free article available at journal site.

Basile, A.S., Janowsky, A., Golembiowska, K., Kowalska, M., Tam, E.,  Benveniste, M., Popik, P., Nikiforuk, A., Krawczyk, M., Nowak, G., Krieter, P.A., Lippa, A.S., Skolnick, P., Koustova E. (2007). Characterization of the Antinociceptive Actions of Bicifadine in Models of Acute, Persistent and Chronic Pain.  J. Pharmacol. Exp. Ther. 321(3):1208-25. PMID: 17325229; Free article available at journal site.

Bhave, S.V., Hornbaker, C., Phang, T.L., Saba, L., Lapadat, R., Belknap, J.K., Tabakoff, B. (2007). The PhenoGen Informatics website: Tools for analyses of complex traits. BMC Genetics 8:59. PMID: 17760997

Hansen, S.T. & Mark, G.P. (2007). Effects of nicotinic receptor antagonism on basal and cocaine-induced dopamine levels in VTA. Society for Neuroscience Abstracts.

Grandy, D.K. (2007). Trace amine-associated receptor 1-Family archetype or iconoclast?Pharmacology and Therapeutics 116(3):355-90. PMC2767338

Kelly, J.X., Smilkstein M.J., Cooper, R.A., Lane, K.D., Johnson, R.A., Janowsky, A., Dodean, R.A., Hinrichs, D.J., Winter, R. and Riscoe, M. (2007). Design, Synthesis, and Evaluation of 10-N-substituted Acridones as Novel Chemosensitizers in Plasmodium falciparum. Antimicrobial Agents and Chemotherapy 51(11):4133-40. 

Raber, J. (2007). Histamine receptor-mediated signaling during development and brain function in adulthood. Cellular and Molecular Life Sciences 64(6):735-741. 
PMID: 17310279

Walter, N.A.R., McWeeney, S.K., Peters, S.T., Belknap, J.K., Hitzemann, R.H. and Buck, K.J. (2007). SNPs matter: Impact on detection of differential expression. Nature Methods 4:679-680. PMID: 17762873


Helms CM, Reeves JM, Mitchell SH. (2006). Impact of strain and D-amphetamine on impulsivity (delay discounting) in inbred mice. Psychopharmacology 188(2):144-51.
PMID: 16915383

Hoffman, W.F., Moore, M., Templin, R., McFarland, B., Hitzemann, R.J., Mitchell, S.H. (2006). Neuropsychological function and delay discounting in methamphetamine-dependent individuals. Psychopharmacology 188:162–170. PMID: 16915378

Malmanger, B., Lawler, M., Coulombe, S., Davison, Cooper, S., Polyakov, Y., Belknap, J.K. and Hitzemann, R. (2006). Further studies on using multiple cross mapping (MCM) to map quantitative trait loci (QTL). Mammal Genome 17(12):1193-204. PMID: 17143586