OHSU

Laboratory of Dr. Charles Allen

Patched cell


Research Interests

The long-term goal of our research is to understand the functional properties of SCN neurons and how the circadian clock regulates these properties. To reach this goal we are pursuing four lines of research (click for a summary of our work in these areas): 

Cellular electrophysiology of the suprachiasmatic nucleus

Regulation of retinal input to the SCN

Role of intracellular Ca2+ as a signaling molecule in the circadian system

Characterization of the retinal ganglion cells projecting to the SCN

 

Publications

Find Dr. Allen's publications on PubMed

 

Lab Members

 

 

Robert Irwin, M.D., MPH

Robert Irwin, M.D., MPH
Senior Investigator

Dr. Irwin received his Bachelor of Science in Chemistry from Portland State University and his M.D. and M.P.H. from Oregon Health & Science University, Portland, Oregon. Dr. Irwin is using cellular imaging techniques to study the role of calcium signaling in the suprachiasmatic nucleus. More information.

 

 

 

 

Mykhalo Moldavan

Mykhaylo Moldavan, Ph.D.

Senior Research Associate

Dr. Moldavan received his Bachelor of Science in Biology from Kyiv State University in Kyiv, Ukraine and his Ph.D in Physiology from the Bogomoletz Institute of Kyiv, Ukraine. He is studying the modulation, by presynaptic receptors, of optic nerve signaling to the suprachia

smatic nucleus. More information.

 

 

 


Nate Klett, B.S.Nate Klett, B.S.

Graduate Student Researcher

Nate received his Bachelor of Science in Neuroscience from University of Pittsburgh in 2008.  Later that year, Nate enrolled in OHSU's Neuroscience Graduate Program, and has since joined the laboratory of Dr. Charles Allen.  Nate's thesis project
examines the intracellular chloride concentration in neurons of the suprachiasmatic nucleus.

 

Allen Lab Summer 2010
The Allen Lab, Summer 2010. From Left: Michelle Sorensen, Celine Croft (summer intern), Chuck Allen, Misha Moldavan, Robert Irwin
34135_1410412952480_1597196262_941992_4424076_n