OHSU

Vollum Institute

The Vollum Institute is dedicated to basic research focusing on gene regulation, structural biology, cell signaling, molecular neuroscience and synaptic modulation with implications for human diseases ranging from autism and other neurodevelopmental disorders to Parkinson's disease, multiple sclerosis, psychiatric diseases and mechanisms of drug addiction.

Mike Forte

Welcome to the Vollum Institute

The Vollum Institute is a privately endowed research institute at Oregon Health & Science University dedicated to basic research that will lead to new treatments for neurological and psychiatric disease. Vollum scientists have broad-ranging interests that coalesce around molecular neurobiology and cellular physiology. Their work has transformed the field of neuroscience and, in particular, have provided important advances in the study of synaptic transmission, neuronal development, neurotransmitter transporters, ion channels and the neurobiology of disease.

Research Highlights

  • Eric Gouaux's lab has determined the atomic resolution structure of an ATP-gated, P2X receptor, thus providing the first molecular 'blueprint' for this important class of ligand-gated ion channel.
  • Gail Mandel's lab identified an unexpected glial cell contribution to the pathogenesis of Rett syndrome.

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