OHSU

Maternal-fetal Medicine Faculty Research

Current Clinical Trials

Faculty in the Ob/Gyn Division of Maternal-fetal Medicine are currently recruiting patients for clinical trials. See trials

Publications

SS Jonker, M Giraud, GD Giraud, N Chattergoon, S Louey, LE Davis, JJ Faber, KL Thornburg.  Myocyte Proliferation Contributes to Anemia induced Fetal Cardiac Enlargement.  Am J Physiol.  Submitted

Hashima JN, Frias AE, Bernard L, Spindel E, Rasanen J.  Fetal right ventricular filling characteristics: role of heart rate and afterload. (submitted)

Rasanen J and Huhta JC. Prostaglandin inhibitors. In: Effects of drugs in the fetus in late pregnancy, Eds: S Montan, I Ingemarsson, K Marsal and T Wheeler. Cambridge University Press. Submitted.

England LJ, Shin Y. K,Tomar S, Ray C,Gupta PC, Eissenberg T, Canttingius S, Tita A Th N, Winn D, Djordjevic M, Lambe M, Stamilio D, Chipato T, Tolosa JE Non-Cigarette Tobacco Use Among Women and Adverse Pregnancy Outcomes (Acta Obst Gyn Scandinavica).

Oncken CH A, Dietz PM, Tong VT, Belizán JM, Tolosa JE, Berghella V, Goldenberg RL, Lando HA, Bloch MH. Prenatal Tobacco Prevention and Cessation Interventions for Women in Low- and Middle-Income Countries  (Acta Obst Gyn Scandinavica).

Tobacco Use and Secondhand Smoke Exposure during Pregnancy in Low- and Middle-Income Countries:  The Need for Social and Cultural Research. Nichter M,  Greaves L,  Bloch M,Paglia M,Scarcini I, Tolosa JE, Novotny T.  (Acta Obst Gyn Scandinavica)

Tolosa JE, Varona M, Durana C, Carrasquilla G, Cardenas O, Torres C, Pardo D,  Leiva MC,  Frumkin H “ Análisis Económico del Uso de la Prueba de Colinesterasa en las Empresas de Flores en Colombia (Report submitted to ASOCOLFLORES- Colombia)-in preparation.

Airoldi J, Pereira L, Cotter A, Gomez R, Berghella V, Prasertcharoensuk W, Rasanen J, Chaithongwongwatthana S, Mittal S, Kearney E and Tolosa JE. Amniocentesis Prior to Physical Exam-Indicated Cerclage in Women with Midtrimester Cervical Dilation: Results from the Expectant Management Compared to Physical Exam-indicated Cerclage International Cohort Study. Am J Perinatol (in press).

Berghella V, Prasertcharoensuk W, Cotter A, Rasanen J, Mittal S, Chaithongwongwatthana S, Gomez R, Kearney E, Tolosa JE and Pereira L. Does Indomethacin Prevent Preterm Birth in Women with Cervical Dilatation in the Second Trimester? Am J Perinatol (in press).

Haapsamo M, Martikainen H and Rasanen J. Low-dose aspirin and uterine haemodynamics on the day of embryo transfer in women undergoing IVF/ICSI: a randomized, placebo-controlled double-blind study. Hum Reprod (in press).

Vanderhoeven JP, Tolosa JE  Tobacco & Preterm Birth.  In Preterm Birth: Prevention and Management. Ed. Vincenzo Berghella. Wiley-Blackwell. London and New York, 2010.

Berghella V, Tolosa JE. In Randomized Clinical Trials of Non-Pharmacologic Treatments: Obstetrics and Gynecology. Taylor & Francis. Ed: Isabelle Boutron, Philippe Ravaud,  David Moher, 2010.

P Robertson, J Faber, LE Davis, D Anderson. Responses of amniotic fluid volume and its four major flows to lung liquid diversion and amniotic infusion in the ovine fetus. Reprod Sci. 2009 Jan;16(1):88-93.  PMID 19144891.

L Bernard, G Ramos, V Fines, AD Hull.  Reducing the cost of detection of congenital heart disease (CHD) in the fetuses of  women with pre-gestational diabetes mellitus.  Ultrasound Obstet Gynecol, 2009; 33(6): 676-82.

KM Gesteland, DF Anderson; LE Davis; P Robertson; JJ.Faber, RA Brace. Intramembranous solute and water fluxes during high intramembranous absorption rates in fetal sheep with and without lung liquid diversion. Am J Obstet Gynecol.  2009 Apr 25 [epub], PMID 19398093.

Airoldi J, Pereira L, Cotter A, Gomez R, Berghella V, Prasertcharoensuk W, Rasanen J, Chaithongwongwatthana S, Mittal S, Kearney E, Tolosa JE. Amniocentesis prior to physical exam indicated cerclage in women with midtrimester cervical dilation:  results from the Expectant Management compared to Physical Exam-indicated Cerclage (EM-PEC) international cohort study. Am J Perin 2009; 26(1):63-8.

Berghella V, Prasertcharoensuk W, Cotter A, Rasanen J, Mittal S, Chaithongwongwatthana S, Gomez R, Kearney E, Tolosa JE, Pereira L. Does indomethacin prevent preterm birth in women with cervical dilatation in the second trimester? Am J Perin 2009; 26(1):13-9.

Rasanen J, Girsen A, Reddy A, Lapidus J, Pouta A, Surcel H, Tolosa J, Gravett M, Nagalla S.  Distinct Maternal Serum Proteomic Profiles of Preeclampsia (PE) in Early Gestation and in Active Disease.  Society for Gynecologic Investigation 2009; 950122.

Bernard L, Hashima J, Hohimer R, Sahn D, Davis L, Rasanen J.  Chronic Fetal Anemia Increased Cardiac Wall Thickness and Preserved Right Ventricular Function During Acutely Increased Afterload.  SMFM Abstract 2009; 198359.

Hashima J, Frias A, Bernard L, Eliot S, Rasanen J.  Fetal Right Ventricular Filling Characteristics: Role of Fetal Heart Rate and Afterload.  SMFM Abstract 2009; 198752.

Bernard L, Hashima J, Hohimer R, Sahn D, Lowell D, Rasanen J.  Fetal Ovine Cardiac Left Ventricular Diastolic and Systolic Function Measured by Tissue Doppler Decreased with Chronic Anemia but the Remodeled Heart Could Respond to Acute Afterload Challenge.  SMFM Abstract 2009; 198857.

Erkinaro T, Kavasmaa T, Ylikauma L, Makikallio K, Haapsamo M, Acharya G, Alahuhta S, Rasanen J.  Placental and Fetal Hemodynamics After Labetalol or Pindolol for Maternal Hypertension in a Chronic Sheep Model of Increased Placental Vascular Resistance and Acute Fetal Hypoxemia.  SMFM Abstract 2009; 199363.

Grigsby P, Rasanen J, Louey S, Thornburg K, Novy M.  An Experimental Model of Placental Insufficiency: Adaptations in Placental Growth and Blood Flow in the Rhesus Monkey.  SMFM Abstract 2009; 199496.

Haapsamo M, Rasanen J, Standley M, Thomas A, Jacob T, Michaels J, Lu X, Lapidus J, Gravett M, Nagalla S.  Maternal Serum Proteome Profile of Early Placentation in IVF is Distinct from Normal Placentation.  SMFM Abstract 2009; 199909.

Rasanen J, Girsen A, Reddy A, Standley M, Thomas A, Jacob T, Michaels J, Lu X, Lapidus J, Gravett M, Nagalla S.  Maternal Serum Biomarkers of Gestational Hypertension Distint from Preeclampsia.  SMFM Abstract 2009; 199926.

Rasanen J, Girsen A, Thomas A, Standley M, Jacob T, Michaels J, Reddy A, Lu X, Lapidus J, Gravett M, Nagalla S.  Maternal Serum Biomarkers of Placental Insufficiency in Pre-Eclampsia.  SMFM Abstract 2009; 199947.

Berghella V, Prasertcharoensuk W, Cotter A, Rasanen J, Mittal S, Chaithongwongwatthana S, Gómez R, Kearney E, Tolosa JE, Pereira L. Does indomethacin prevent preterm birth in womenwith cervical dilatation in the second trimester?  Am J of Perinatology. 26(1):13-9, 2009 Jan.

Airoldi J, Pereira L, Cotter A, Gómez R, Berghella V, Prasertcharoensuk W, Rasanen J

Chaithongwongwatthana S, Mittal S, Kearney E, Tolosa JE Amniocentesis prior to physical exam indicated cerclage in women wit midtrimester cervical dilation: results from the Expectant Management compared to Physical Exam-Indicated Cerclage (EM-  PEC) international cohort study American Journal of Perinatology. 26(1):63-8, 2009 Jan.

Landon MB, Spong CY, Thom E, Carpenter MW,  Ramin SM, Casey B, Wapner RJ, Varner  MW, Rouse DJ, Thorp, JM Jr., Sciscione A, Catalano P, Harper M, M.D. M.Sc., Saade G,. Lain KY, Sorokin Y, Peaceman AM, Tolosa, JE, Anderson GB. for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network, Bethesda, MD. Multicenter Randomized Treatment Trial of Mild Gestational Diabetes. N Engl J Med 2009;361:1339-48.

Tolosa J.E, Saade G.  Hazards to  Pregnancy: Tobacco , Alcohol and the Environment. In:  Protocols in High Risk Pregnancies 5th edition. Ed: Queenan J.T., Hobbins J.C.,   Spong C. Y. Wiley-Blackwell, 2009.

SS Jonker, DF Anderson, LE Davis, Q  Yang, JJ Faber and G D Giraud. Persistent changes in arterial blood gases in fetal sheep. Laboratory Animals. 423:326-330, 2008.  PMID  18625587

Q Yang, AR Hohimer, GD Giraud, DM Van Winkle, MJ Underwood, GW He and LE Davis.  Effect of fetal anaemia on myocardial ischemia-reperfusion injury and coronary vasoreativity in adult sheep. Acta Physiol (Oxf). 2008 Dec;194(4):325-34. Epub 2008 Sep 20.  PMID 18729844

Jones CA, London NR, Chen H, Park KW, Sauvaget D, Stockton RA, Wythe JD, Suh W, Larrieu-Lahargue F, Mukouyama Y, Lindblom P, Seth P, Frias A, Nishiya N, Ginsberg MH, Gerhardt H, Zhang K and Li DY.  Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability.  NATURE MEDICINE 2008; 14(4):448-453 (Cover Article).

Oh KY, Frias AE Jr, Byrne LB, Kennedy AM.  Isolated short femur – What could this mean? Ultrasound Q 2008; 24(2):89-92.

Acharya G, Räsänen J, Mäkikallio K, Erkinaro T, Kavasmaa T, Haapsamo M, Mertens L and Huhta JC. Metabolic acidosis decreases fetal myocardial isovolumic velocities in a chronic sheep model of increased placental vascular resistance. Am J Physiol Heart Circ Physiol 294:H498-504, 2008.

, Räsänen J, Mäkikallio T, Vuolteenaho O and Huhta JC. Human fetal cardiovascular profile score and neonatal outcome in intrauterine growth restriction. Ultrasound Obstet Gynecol 31:48-54, 2008.

Huilaja L, Hurskainen T, Autio-Harmainen H, Hofmann SC, Sormunen R, Räsänen J, Ilves M, Franzke CW, Bruckner-Tuderman L and Tasanen K. Pemphigoid gestationis autoantigen, transmembrane collagen XVII, promotes the migration of cytotrophoblastic cells of placenta and is a structural component of fetal membranes. Matrix Biol 27:190-200, 2008.

Girsen A, Ala-Kopsala M, Makikallio K, Vuolteenaho O and Rasanen J. Fetal cardiac natriuretric peptide secretion is increased in pregnancies complicated by maternal type-1 diabetes. Acta Obstet Gynecol Scand 87:307-312, 2008.

Tahkola J, Räsänen J, Sund M, Mäkikallio K, Autio-Harmainen H and Pihlajaniemi T. Cardiac dysfunction in transgenic mouse fetuses overexpressing shortened type XIII collagen. Cell Tissue Res 333:61-69, 2008.

Haapsamo M, Martikainen H and Rasanen J. Low-dose aspirin reduces uteroplacental vascular impedance in early and mid gestation in IVF and ICSI patients: a randomized, placebo-controlled double-blind study. Ultrasound Obstet Gynecol 32:687-693, 2008.

Kavasmaa T, Mäkikallio K, Erkinaro T, Acharya G, Haapsamo M, Alahuhta S and Räsänen J. Significance of retrograde diastolic uterine artery blood flow during regional anaesthesia in instrumented pregnant sheep. Acta Anaesthesiol Scand 52:1291-1297, 2008.

Patel D, Cuneo B, Viesca R, Rasanen J, Leshko J and Huhta J. Digoxin for the treatment of fetal congestive heart failure with sinus rhythm assessed by cardiovascular profile score. J Matern Fetal Neonatal Med 21:477-482, 2008.

Rasanen J, Girsen A, Lu X, Lapidus J, Tolosa J, Gravett M, Nagalla S.  First Trimester Maternal Serum Biomarkers for Prediction of Preeclampsia.  (SMFM Abstract) Am J Obstet Gynecol 2008; 197:6.

Haapsamo M, Rasanen J.  Low-Dose Aspirin Reduces Uteroplacental Vascular Impedance During the First Half of Pregnancy in IVF/ICSE Patients: A Randomized Placebo-controlled Study. (SMFM Abstract) Am J Obstet Gynecol 2008; 197:6.

Ness A, Pereira L, Cotter A, Berghella V, Gomez R, Prasertcharoensuk W, Rasanen J, Chaithongwon-Watthana S, Mittal S, Daly S, Tolosa J.  Predictors of Outcome With Expectant Management of Threatened Preterm Delivery in the2nd Trimester: Results From the Global Network for Perinatal and Reproductive Health (GNPRH) International Cohort Study. (SMFM Abstract) Am J Obstet Gynecol 2008; 197:6.

Haapsamo M, Rasanen J, Gravett M, Nagalla S.  Low-Dose Aspirin Influences Early Pregnancy Placentation in IVF/ICSI Patients: Evidenced By a Distinct Maternal Serum Proteome Profile. (SMFM Abstract) Am J Obstet Gynecol 2008; 197:6.

Stephenson-Famy A, Hitti J, Lu X, Lapidus J, Girsen A, Rasanen J, Gravett M, Nagalla S.  Comprehensive Proteomic Analysis of First, Second and Third Trimester Maternal Serum: Gestational Age-Dependent Changes in the Maternal Serum Proteome.  (SMFM Abstract) Am J Obstet Gynecol 2008; 197:6.

Acharya G, Rasanen J, Makikallio K, Erkinaro T, Kavasmaa T, Haapsamo M, Mertens L, Huhta J.  Metabolic Acidosis Decreases Fetal Myocardial Isovolumic Velocities in a Chronic Sheep Model of Increased Placental Vascular Resistance.  (SMFM Abstract) Am J Obstet Gynecol 2008; 197:6.

Rasanen J, Girsen A, Lu X, Lapidus J, Tolosa J, Gravett M, Nagalla S.  Maternal Serum Biomarkers in Preeclampsia.  (SMFM Abstract) Am J Obstet Gynecol 2008; 197:6.

Crawford JT, Tolosa JE, Goldenberg RL Smoking Cessation in Pregnancy: why, how, and what next… Clinics in Ob Gyn, 2008; 51 (2), 419-435.

LS Bernard.  A postoperative complication causing physician consternation. Obstet Gynecol.  2007; 109: 1445-6.

Oh KY, Rassner U, Frias AE Jr, Kennedy AM.  The fetal posterior fossa: Clinical correlation of findings on prenatal ultrasound and fetal magnetic resonance imaging. Ultrasound Q 2007; 23(3):203-210.

Crawford JT, Edelman AB, Pereira L, Bednarek P, Buckmaster J. The effects of vasopressin injection on uterine artery blood flow during dilation and evacuation. Am J Obstet Gynecol 2007;196(5):e38-9.

Gravett MG, Novy MJ, Thomas A, Schneider KA, Reddy, Dasari S, Jacob T, Lu X, Rodland M, Pereira L, Sadowsky DW, Roberts, Jr. CT, Nagalla SR.  Proteomic analysis of cervical-vaginal fluid: Identification of novel biomarkers for detection of intra-amniotic infection.J Proteome Res 2007; 6(1):89-96.

Pereira L, Reddy AP, Jacob T, Thomas A, Schneider KA, Dasari S, Lapidus JA, Lu X, Rodland M, Roberts CT Jr., Gravett MG, Nagalla SR. Identification of novel protein biomarkers of preterm birth in human cervical-vaginal fluid.  J Proteome Res 2007;6(4):1269-76.

Dasari S, Pereira L, Reddy AP, Michaels J, Lu X, Jacob T, Thomas A, Rodland M, Roberts, Jr. CT, Gravett MG, Nagalla SR. Comprehensive proteomic analysis of human cervical-vaginal fluid. J Proteome Res 2007; 6(4):1258-68.

Michaels JE, Dasari S, Pereira L, Reddy AP, Lapidus JA, Lu X, Jacob T, Thomas A, Rodland, M, Roberts CT Jr. Gravett MG, Nagalla SR. Comprehensive proteomic analysis of the human amniotic fluid proteome: gestational age-dependent changesJ Proteome Res 2007; 6(4):1277-85.

Mateus J, Pereira L, Baxter J, Berghella V, Tolosa J. The Effectiveness of Fetal Fibronectin Testing Compared to Digital Cervical Assessment in the Triage of Women with Preterm Contractions. Am J Perin 2007; 24(6):381-5.

Pereira L, Cotter A, Gómez R, Berghella V, Prasertcharoensuk W, Chaithongwongwatthana S, Rasanen J, Mittal S, Daly S, Airoldi J, Tolosa JE. Expectant management compared to physical exam-indicated cerclage in selected women with a dilated cervix between 140/7-256/7 weeks: Results from the EM-PEC international cohort study. Am J Obstet Gynecol 2007; 197(5):483-5.

Girsen A, Ala-Kopsala M, Mäkikallio K, Vuolteenaho O and Räsänen J. Cardiovascular haemodynamics and umbilical artery N-terminal peptide of proB-type natriuretic peptide in human fetuses with growth restriction. Ultrasound Obstet Gynecol 29:296-303, 2007.

Acharya G, Sitras V, Erkinaro T, Mäkikallio K, Kavasmaa T, Päkkilä M, Huhta JC and Räsänen J. Experimental validation of uterine artery volume blood flow measurement by Doppler ultrasonography in pregnant sheep. Ultrasound Obstet Gynecol 29:401-406, 2007.

Girsen A, Mäkikallio K, Hiilesmaa V, Hämäläinen E, Teramo K and Räsänen J. The relationship between human fetal cardiovascular hemodynamics and serum erythropoietin levels in growth restricted fetuses. Am J Obstet Gynecol 196:467, e1-6, 2007.

Erkinaro T, Makikallio K, Acharya G, Pakkila M, Kavasmaa T, Huhta JC, Alahuhta S and Rasanen J. Divergent effects of ephedrine and phenylephrine on cardiovascular hemodynamics of near-term fetal sheep exposed to hypoxemia and maternal hypotension. Acta Anaesthesiol Scand 51:922-928, 2007.

Pereira L, Cotter A, Gómez R, Berghella V, Prasertcharoensuk W, Rasanen J, Chaithongwongwatthana S, Mittal S, Daly S, Airoldi J and Tolosa JE.  Expectant management compared with physical examination-indicated cerclage (EM-PEC) in selected women with a dilated cervix at 14(0/7)-25(6/7) weeks: results from the EM-PEC international cohort study. Am J Obstet Gynecol 197: 483.e1-483.e8, 2007.

Makikallio K, Acharya G, Erkinaro T, Haapsamo M, Kavasmaa T, Huhta J, Rasanen J.  Ductus Venosus Velocimetry in Fetal Hypoxia and Acidemia.  (SMFM Abstract) Am J Obstet Gynecol 2007; 195:6.

Berghella V, Prasertcharoensuk W, Cotter A, Rasanen J, Mittal S, Chatthongwongwatthana S, Gomez R, Kearney E, Tolosa JE, Pereira L.  Does Indomethacin Prevent Preterm Birth in Women with Cervical Dilation and Cerclage in the Second Trimester?  Expectant Management Compared to Physical Exam-indicated Cerclage (EM-PEC) International Cohort Study.  (SMFM Abstract) Am J Obstet Gynecol 2007; 195:6.

Nagalla S, Gravett M, Pereira L, Hitti J, Eschenbach D, Jacobsson B, Rasanen J, Luthy D.  The Pregnancy Proteome: Enabling the Next Era of Comprehensive Prognostic and Diagnostic Monitoring of Maternal-Fetal Health.  (SMFM Abstract) Am J Obstet Gynecol 2007; 195:6.

Rasanen J, Tolosa JE, Girsen A, Pereira L, Fang LX, Lapidus J, Gravett M, Nagalla S.  Prediction of Preeclampsia During Early Gestation Using Proteomic Analysis of Maternal Serum.  (SMFM Abstract) Am J Obstet Gynecol 2007; 195:6.

Girsen A, Rasanen J, Tolosa J, Pereira L, Gravett M, Nagalla S.  First-Trimester Detection of Preeclampsia by Serum Glycoproteome Analysis.  (SMFM Abstract) Am J Obstet Gynecol 2007; 195:6.

Girsen A, Makikalllio K, Ala-Kopsala M, Vuolteenaho O, Rasanen J.  Fetal Cardiac Natriuretc Peptides are Increased in Type I Diabetic Pregnancies.  (SMFM Abstract) Am J Obstet Gynecol 2007; 195:6.

Makikallio K, Rasanen J, Huhta J.  Fetal Central and Peripheral hemodynamic Parameters and Neonatal Outcome in Intrauterine Growth Restriction.  (SMFM Abstract) Am J Obstet Gynecol 2007; 195:6.

Airoldi J, Pereira L, Gomez R, Cotter A, Rasanen J, Kearney E, Mittal S, Chaithongwongwtthana S, Prasertcharoensuk W, Tolosa JE.  Amniocentesis Does Not Contribute to Preterm Birth Prior to 28 Weeks in Women with Midtrimester Cervical Dilation:  Results from the Expectant Management Compared to Physical Exam-Indicated Cerclage (EM-PEC) International Cohort Study.  (SMFM Abstract) Am J Obstet Gynecol 2007; 195:6.

Robertson P, Chaithongwongwatthana S, Daly S, Pereira L, Rasanen J, Cotter A, Prasertcharoensuk W, Gomez R, Mittal S, Berghella V, Limpongsanurak S, Tolosa JE.  McDonal vs. Shirodkar: Outcomes in the Expectant Management Compared to Physical Exam-Indicated Cerclage (EM-PEC) International Cohort Study.  (SMFM Abstract) Am J Obstet Gynecol 2007; 195:6.

Goldberg J, Wolf A, Silberstein S, Gebeline-Myers C, Hopkins M, Einhorn K, Tolosa JE Evaluation of an electronic diary as a Diagnostic Tool to Study Headache and Premenstrual Symptoms in Migraineurs. Headache 2007; 47;384-396.

Sood S, Mohanty S, Kapil A, Tolosa JE, Mittal S InPouch TM TV Culture for detection of Trichomonas Vaginalis.  Indian Journal of Medical Research (IJMR), 125, Apr 2007. pp567-571.

Mateus J, Pereira L, Baxter J, Berghella V, Tolosa JE. Effectiveness of Fetal Fibronectin Testing Compared with Digital Cervical Assessment of Women with Preterm Contractions. Am J Perinatol, 24 (6) 381-385, June 2007.

Pereira L, Cotter A, Gómez R, Berghella V, Prasertcharoensuk W, Rasanen J, Chaithongwongwathana S, Mittal S, Daly S, Airoldi J, Tolosa JE. Expectant management compared to physical exam-indicated cerclage (EM-PEC) in selected women with a dilated cervix between 14 0/7-25 6/7 weeks: Results from the EM-PEC international cohort study. Am J Obstet Gynecol 2007;197:483.e1-483.e8.

Friel LA. Romero R. Edwin S. Nien JK. Gomez R. Chaiworapongsa T. Kusanovic JP. Tolosa JE. Hassan SS. Espinoza J. The calcium binding protein, S100B, is increased in the amniotic fluid of women with intra-amniotic infection/inflammation and preterm labor with intact or ruptured membranes. Journal of Perinatal Medicine. 35(5):385-93, 2007.

Mohanty S. Xess I. Hasan F. Kapil A. Mittal S. Tolosa JE. Prevalence & susceptibility to fluconazole of Candida species causing vulvovaginitis. Indian Journal of Medical Research. 126(3):216-9, 2007 Sep.

R Brace, C Cheung, LE Davis, R Gagnon, R Harding, J Widness. Sources of amniotic fluid erythropoietin during normoxia and hypoxia in fetal sheep. Am J Obstet Gynecol 2006 Jul;195(1):246-54

DD. Giraud, JJ Faber, SS. Jonker, LE Davis, DF Anderson. Effects of intravascular infusions of plasma on placental and systemic blood flow in fetal sheep. Am J Physiology 291 H2884, 2006. 

Sullivan AE, Nelson L, Frias AE, Porter TF, Branch DW, and Silver RM.  The aryl hydrocarbon receptor nuclear translocator gene polymorphism in patients with recurrent miscarriage.  Am J Reprod Immunol 2006; 55(1):51-3. 

Goldberg J, Pereira L. Pregnancy outcomes following treatment for fibroids: Uterine fibroid embolization versus laparoscopic myomectomy. Curr Opin Obstet Gynecol 2006; 18:402-6.

Crawford JT, Pereira L, Buckmaster J, Gravett MG, Tolosa JEAmniocentesis results and novel proteomic analysis in a case of occult candidal chorioamnionitis. J Mat Fet Med 2006; 19(10): 667-70.

Mäkikallio K, Erkinaro T, Niemi N, Kavasmaa T, Acharya G, Päkkilä M and Räsänen J. Fetal oxygenation and Doppler ultrasonography of cardiovascular hemodynamics in a chronic near term sheep model. Am J Obstet Gynecol 194:542-550, 2006.

Mäkikallio K, Rounioja S, Vuolteenaho O, Paakkari J, Hallman M and Räsänen J. Fetal cardiac natriuretic peptide expression and cardiovascular hemodynamics in endotoxin-induced acute cardiac dysfunction inmouse. Ped Res 59:180-184, 2006.

Erkinaro T, Kavasmaa T, Pakkila M, Acharya G, Makikallio K, Alahuhta S and Rasanen J. Ephedrine and phenylephrine for the treatment of maternal hypotension in a chronic sheep model of increased placental vascular resistance. Br J Anaesth 96:231-237, 2006.

Acharya G, Rasanen J, Kiserud T and Huhta JC. The fetal cardiac function. Current Cardiology Reviews 2:41-53, 2006.

Berghella V, Pelham J, Sabogal JC, Sciscione A, Tolosa JE, Shah S, Wapner The Maternal-Fetal Medicine Fellowship Match System: Effectiveness at Identifying Successful Clinician-Investigators at 1 Institution J Rep Med 2006; 51:416-420.

Yamasmit W, Chaithongwongwatthana S, Tolosa JE Prenatal Vitamin K1 Administration in Epileptic Women to Prevent Neonatal Hemorrhage: Is it effective? J of Reprod Med 2006; 51:463-466.

Tolosa JE  Chlorhexidine antisepsis to reduce neonatal mortality needs to be adopted globally (Invited Commentary) Ped Inf Dis J, 25(8) August 2006, 676-679.

DeFalco LM. Sciscione AC. Megerian G. Tolosa J. Macones G. O'Shea A. Pollock MA. Inpatient versus outpatient management of monoamniotic twins and outcomes.  American Journal of Perinatology. 23(4):205-11, 2006 May.

Crawford JT, Pereira L, Buckmaster J, Gravett MG, Tolosa, JE, Amniocentesis results and novel proteomic analysis in a case of occult candidal chorioamnionitis (The J of Mat-Fet & Neon Med, Oct 2006;19 (10):667-670.

Tolosa JE, Chaithongwongwatthana S, Daly S, Win WM, Gaitan H, Lumbiganon P, Festin M, Chipato T, Sauvarin J, Goldenberg R, Andrews W, Whitney C  The International Infections in pregnancy (IIP) Study: Variations in the Prevalence of Bacterial Vaginosis and Distribution of Morphotypes in vaginal Smears among Pregnant Women. Am J Obstet Gynecol. 2006 Nov;195(5):1198-204. (Editor’s Choice).

D Anderson, Q Yang, AR Hohimer, J Faber, G Giraudand, L Davis .  Intramembranous Absorption Rate is Unaffected by Changes in Amniotic Fluid Composition. Am J Physiology. 288 F964-968, 2005.

J Faber, D Anderson, R Hohimer, Q Yang, GD Giraud, L Davis.  The function curve of the membranes that regulate amniotic fluid volume in sheep. Am J Physiology 289 H146-150, 2005.

LE Davis, KL Thornburg and G Giraud Anemia as a Programming agent in the Fetal Heart. J Physiology 565: 35-41, 2005.

G. Giraud, J. Faber, S. Jonker, L Davis, and D. Anderson. Intravascular Infusions of Plasma Into Fetal Sheep Cause Arterial and Venous Hypertension. J Appl Physiol, 99(3) 884, 2005.

Oh KY, Kennedy AM, Frias AE Jr, Byrne JLB.  Fetal Schizencephaly: Prenatal and postnatal imaging with a review of the clinical manifestations.  Radiographics 2005; 25(3):647-657.

Pereira L, Gould R, Pelham J, Goldberg J. Correlation Between Visual Examination of the Cervix and Digital Examination. J Mat Fet Neonat Med 2005; 17(3):223-7.

Roman AS, Rebarber A, Pereira L, Sfakianaki AK, Mulholland J, Berghella V. The efficacy of sonographically indicated cerclage in multiple gestations. J Ultrasound Med 2005; 24:763-8.

Pereira L, Culhane J, McCollum K, Agnew K, Nyirjesy P. Variation in microbiologic profiles among pregnant women with bacterial vaginosis. Am J Obstet Gynecol 2005:193(3):746-51.

Berghella V, Baxter J, Pereira L. Cerclage: Should we be doing them? Contemporary Ob/GYN. 2005:50(11):34-41.

Mäkikallio K, Jouppila P and Räsänen J. Human fetal cardiac function during the first trimester of pregnancy. Heart 91:334-338, 2005.

Päkkilä M, Räsänen J, Heinonen S, Tinkanen H, Tuomivaara L, Mäkikallio K, Hippeläinen M, Tapanainen JS and Martikainen H. Low-dose aspirin does not improve ovarian responsiveness or pregnancy rate in IVF and ICSI patients: a randomized, placebo-controlled double-blind study. Hum Reprod 20:2211-2214, 2005.

Rounioja S, Rasanen J, Ojaniemi M, Glumoff V, Autio-Harmainen H and Hallman M. Mechanism of acute fetal cardiovascular depression after maternal inflammatory challenge in mouse. Am J Pathol 166:1585-1592, 2005.

Kaukola T, Räsänen J, Herva R, Patel DD and Hallman M. Suboptimal neurodevelopment in very preterm infants is related to fetal cardiovascular compromise in placental insufficiency. Am J Obstet Gynecol 193:414-420, 2005.

Varona M.E., Tolosa JE, Cardenas O, Torres CH, Pardo D, Carrasquilla G, Frumkin H.  Descripción  del Uso y Manejo de Plaguicidas en las Empresas de Flores Afiliadas a Asocolflores. Biomédica, 2005.

Cotter A, Ness A, Tolosa JE Prophylactic oxytocin for the third stage of labour. Cochrane Review 2005.

Tolosa J.E., Chaithongwongwatthana S.  Hazards in Pregnancy: Smoking.  In: Protocols in High Risk-Pregnancies 4th edition. Queenan J.T., Hobbins J.C., Spong C. Y. (eds) Blackwell Science, 2005.

Crawford JT, Tolosa JE  Guideline for Smoking Cessation in Pregnancy; in Obstetrics & Maternal-Fetal Medicine:Evidenced-based Guidelines,Taylor & Francis;Ed: Berghella V, 2005.

Crawford JT, Berghella V, Tolosa JE  Guideline for management of the normal third stage of labor; in Obstetrics & Maternal-Fetal Medicine: Evidenced-based Guidelines, Taylor & Francis; Editor Berghella V, 2005.

Wyatt SM, Kraus FT, Roh CR, Elchalal U, Nelson DM, Sadovsky Y. The correlation between sampling site and gene expression in the term human placenta. Placenta 2005; 26(5):372-9.

Qin Yang, Davis L, Hohimer A, Faber J, Anderson D. Regulatory Response to Washout of Amniotic Fluid in Sheep. Am J Physiology 288 H1339-1343, 2004.   

Frias AE Jr, Luikenaar RA, Sullivan AE, Lee RM, Porter TF, Branch DW and Silver RM, Poor obstetric outcome in subsequent pregnancies in women with prior fetal death.  Obstet Gynecol 2004; 104(3):521-6.

Levy C, Pereira L, Dardarian T, Cardonick E. Solid Pseudopapillary Pancreatic Tumor in Pregnancy: A Case Report. J Reprod Med 2004; 49(1):61-4.

Goldberg J, Pereira L, Berghella V, Diamond J, Darai E, Seinera P, Seracchioli R.  Pregnancy outcomes after treatment for fibromyomata: Uterine artery embolization versus laparoscopic myomectomy. Am J Obstet Gynecol 2004,191(1):18-21.

Yamasmit W, Chaithongwongwatthana S, Tolosa JE, Limpongsanurak S, Pereira L, Cheku B, Lumbiganon P. Prophylactic oral betamimetics for preventing preterm birth in women with a twin pregnancy. [Protocol] Cochrane Pregnancy and Childbirth Group Cochrane Database of Systematic Reviews. 3, 2004.

Berghella V, Pereira L, Gariepy A, Simonazzi G. Prior cone biopsy: prediction of preterm birth by cervical ultrasound. Am J Obstet Gynecol 2004; 191(4):1393-7.

Acharya G, Erkinaro T, Mäkikallio K, Lappalainen T and Räsänen J. Relationships among Doppler-derived umbilical artery absolute velocities, cardiac function, and placental volume blood flow and resistance in fetal sheep. Am J Physiol Heart Circ Physiol 286:H1266-H1272, 2004.

Erkinaro T, Makikallio K, Kavasmaa T, Alahuhta S and Rasanen J. Effects of ephedrine and phenylephrine on uterine and placental circulations and fetal outcome following fetal hypoxaemia and epidural-induced hypotension in a sheep model. Br J Anaesth 93:825-832, 2004.

Lewis D, Tolosa JE, Kaufmann M, Goodman M, Farrell C, Berghella V.  Myelomeningocele: Does mode of delivery affect long-term motor function or ambulatory status? Obstet Gynecol  2004;103:469-73.

Sabogal JC, Becker E, Bega G, Komwilaisak R, Berghella V, Weiner S, Tolosa JE.  Reproducibility of Fetal Lung Volume Mesurements with 3-Dimensional Ultrasonography. Journal Ultrasound Med 23:347-352, 2004

Whitney C, Daly S, Limpongsanurak S, Festin M, Thinn K K, Chipato T, Lumbiganon P., Sauvarin J, Andrews W, Tolosa JE.  “International Infections in Pregnancy Study (the IIP Study): Group B Streptococcal Colonization in Pregnant Women J of Mat-Fet Neo Med 2004;15:267-274

Lumbiganon P, Thinkhamrop B, Thinkhamrop J, Tolosa JE  Vaginal Clorhexidine During Labour for Preventing Peripartal and Neonatal (excluding GBS and HIV) Infections Cochrane Systematic  Reviews, 4, 2004.

Yamasmit, W. Chaithongwongwatthana, S. Tolosa, JE. Limpongsanurak, S. Pereira, L. Cheku, B. Lumbiganon, P. Prophylactic oral betamimetics for preventing preterm birth in women with a twin pregnancy. Cochrane Database of Systematic Reviews. 4, 2004.

Berghella V, Odibo A, Tolosa JE. Cerclage for prevention of preterm birth in women with a short cervix found on transvaginal ultrasound: A randomized trial. Am J Obstet Gynecol 2004, 191, 1311-7.

Yamasmit W, Chaithongwongwatthana S, Charoenvidhya D, Uerpairojkit B, Tolosa JE  RandomUrinary protein-to-creatinine ratio for detection of significant proteinuria in preeclampsia J of Mat-Fet Neon Med 2004;16:275-279

Lumbiganon P. Thinkhamrop J. Thinkhamrop B. Tolosa JE. Vaginal chlorhexidine during labour for preventing maternal and neonatal infections (excluding Group B Streptococcal and HIV). Cochrane Database of Systematic Reviews. (4):CD004070, 2004.

Chaithongwongwatthana, S. Yamasmit, W. Limpongsanurak, S. Lumbiganon, P. DeSimone, JA. Baxter, J. Tolosa, JE. Pneumococcal vaccination during pregnancy for preventing infant infection. Cochrane Database of Systematic Reviews. 4, 2004.

Kruger J, Tolosa J.E.  Prenatal Testing. In: Neonatology: Management, Procedures, On-Call Problems, Diseases, Drugs, 5th edition. Gomella T.L., Cunningham M.D, Eyal F.G., Zenk K.E. (eds), McGraw-Hill Companies, Inc., 2004.

AR Hohimer, M Mysliwiec, K Lee, LE Davis and GA Pantely M.D.  Perinatal hypoxia causes ventricular enlargement associated with increased atrial natriuretic peptide (ANP) mRNA levels in newborn mice. High Altitude Medicine and Biology: Summer;4(2):241-54. 2003

C. Broberg, GD Giraud, J Schultz, KL Thornburg, AR Hohimer, L Davis. Fetal anemia leads to augmented contractile response to hypoxic stress in adulthood. Am J Physiol. 285(3):R649-55, 2003

C Broberg, G Pantey, B Barber, K Lee, T Thigpen, LE Davis, D Sahn, AR Hohimer.  Validation of the myocardial performance index (MPI) by echocardiography in mice: a non-invasive measure of left ventricular function. J Am Society Echocardiography: 16(8):814-23. Aug. 2003

Frias AE Jr and Belfort MA. Post Magpie: How should we be managing Severe Preeclampsia.  Curr Opin Obstet Gynecol 15(6):489-95. 2003

Goldberg J, Pereira L, Mude-Nochumson H. Uterine artery embolization for symptomatic fibroids: Pros and cons. OBG Management;15(3):69-79. 2003.

Pereira L. Obstetric Management of the Patient with Spinal Cord Injury. Obstet Gynecol Survey 2003;58(10):678-86.

Pereira L, Jenkins T, Berghella V. Conventional Management of Fetal Alloimmunization Compared to Management by Middle Cerebral Artery Peak Systolic VelocityAm J Obstet Gynecol 2003; 189(4):1002-6.

LE Davis, J Widness, R Brace. Renal and Placental Secretion of Erythropoietin during anemia or hypoxia in the ovine fetus. Am J Obstet Gynecol 189:1764, 2003.

SJ Jonker, LE Davis, J van der Bilt, B Hadder, AR Hohimer, GD Giraud, KL Thornburg. Anaemia stimulates aquaporin 1 expression in the fetal sheep heart. Experimental Physiology 88(6):691-8, 2003.

Rounioja S, Räsänen J, Glumoff V, Ojaniemi M, Mäkikallio K and Hallman M. Intra-amniotic lipopolysaccharide leads to fetal cardiac dysfunction – a mouse model for fetal inflammatory response. Cardiovasc Res 60:156-164, 2003.

Mäkikallio K, Jouppila P and Räsänen J. Retrograde aortic isthmus net blood flow and human fetal cardiac function in placental insufficiency. Ultrasound Obstet Gynecol 22:351-357, 2003.

Segel, SY, Miles, AM, Clothier, B, Parry, S, Macones, GA: Duration of antibiotic therapy after preterm premature rupture of fetal membranes. Am J Obstet Gynecol. 189:799-802, 2003.

Segel, SY: Cardiovascular Disease in Pregnancy. In: Bader TJ (ed) Ob/Gyn Secrets Third Edition.  Philadelphia, Hanley & Belfus, Inc., 2003

Segel, SY: Disorders of Amniotic Fluid. In: Bader TJ (ed) Ob/Gyn Secrets Third Edition.  Philadelphia, Hanley & Belfus, Inc., 2003

Goldberg J, Hyslop T, Tolosa JE, Sultana C Racial Differences in Severe Perineal Lacerations Following Vaginal Delivery. Am J Obstet Gynecol 2003; 188(4), 1063-7.

Festin M, Lumbiganon P, Tolosa JE, Finney K A, Ba-Thike K, Chipato T, Gaitán H, Lianghzi X, Limpongsanurak S, Mittal S, Peedicayil A, Pramono N, Purwar M, Sheenoy S, Daly S International Survey on Practice Variations in the Management of the Third Stage of Labor. Bulletin of the World Health Organization 2003; 81-286-9

Straughn H, Goldenberg R, Tolosa JE, de Codes J, Daly S, Festin M, LimpongsanurakS, Lumbiganon P, Paul VK, Peedicayil A,  Purwar M, Sabogal JC, Shenoy S.  "Birthweight-Specific Neonatal Mortality in developing Countries and Obstetric Practices” Int J Gyn & Obst 2003: 80(1) 71-78.

Jenkins TM. Mackey SF. Benzoni EM. Tolosa JE. Sciscione AC. Non-obstetric surgery during gestation: risk factors for lower birthweight. Australian & New Zealand Journal of  Obstetrics & Gynecology. 43(1):27-31, 2003 Feb.

Thinkhamrop J. Limpongsanurak S. Festin MR. Daly S. Schuchat A. Lumbiganon P. Zell E Chipato T. Win AA. Perilla MJ. Tolosa JE. Whitney CG. Infections in international pregnancy study: performance of the optical immunoassay test for detection of group B streptococcus. Journal of Clinical Microbiology. 41(11):5288-90, 2003 Nov.

Andolina K, Tolosa JE, Monzo J, Roberts N, Daly S  “Oral Misoprostol is Rapidly Absorbed  in Women in Postpartum at Term” J of Mat-Fet and Neo Med 2003; 14:229-232.

Berghella V, Bega G, Tolosa JE, Berghella M Ultrasound Assessment of the Cervix Clinical Obstetrics & Gynecology. 46(4):947-62, 2003 Dec.

D Wothe, AR Hohimer, M Morton, KL Thornburg, GD Giraud, L Davis. Increased coronary blood flow signals growth of coronary resistance vessels in near-term ovine fetuses.  Am J Physiol. R282: R295-R302, 2002

LE Davis, JB Roullet, KL Thornburg, M Shokry, AR Hohimer, GD Giraud. Augmentation of coronary conductance in adult sheep made anemic during fetal life. J Physiology 547(1):53-59.

Pereira L, Donnenfeld AE.  Meckel Syndrome.  In: NORD Guide to Rare
Diseases, Williams and Wilkins, 2002.

Goldberg J, Shah S, Pereira L, Taylor J, Klein T. “Placenta Accreta” Letter to the editor. Obstet Gynecol  99(6):1133-4. 2002.

Goldberg J, Pereira L, Berghella V. Pregnancy following uterine artery embolization: a report of two cases and review of the current literature. Obstet Gynecol 100(5):869-72. 2002

Mäkikallio K, Vuolteenaho O, Jouppila P and Räsänen J. Ultrasonographic and biochemical markers of human fetal cardiac dysfunction in placental insufficiency. Circulation 105:2058-2063, 2002.

Mäkikallio K, Jouppila P and Räsänen J. Retrograde net blood flow in the aortic isthmus in relation to human fetal arterial and venous circulations. Ultrasound Obstet Gynecol 19:147-152, 2002.

Broth RE, Wood DC, Rasanen J, Sabogal JC, Komwilaisak R, Weiner S and Berghella V. Prenatal prediction of lethal pulmonary hypoplasia: The hyperoxygenation test for pulmonary artery reactivity. Am J Obstet Gynecol 187:940-945, 2002.

Mäki JM, Räsänen J, Tikkanen H, Sormunen R, Mäkikallio K, Kivirikko KI and Soininen R. Inactivation of the lysyl oxidase gene Lox leads to aortic aneurysms, cardiovascular dysfunction, and perinatal death in mice. Circulation 106:2503-2509, 2002.

Segel SY, Macones GA: Fetal abdominal wall defects and mode of delivery: A systematic  review. Letter to the editor. Obstet Gynecol. 99:521-522, 2002.

Goldberg J, Holtz D, Hyslop T, Tolosa JE  Has the use of routine episiotomy decreased?  Examination of episiotomy rates from 1983 to 2000. Obstet Gynecol 99:395-400. 2002.

Dunton CJ, King SA, Neufeld J, Tolosa J, Perez G, Avila A, Underhill K Phase I Study of Topotecan and Radiation Therapy in Advanced Cervical Cancer. Gynecologic Oncology; 85 185-187. 2002.

Chaioworapongsa T, Espinoza J, Yoshimatsu J, Kalache K, Edwin S, Blackwell S, Yoon BH, Tolosa JE, Silva M, Behnke E, Gomez R, Romero R  Subclinical myocardial injury in small- for-gestational-age neonates  J Mat Fet and Neonat Med 11 (6):385-90. 2002.

Tolosa JE, Antibiotic Treatment for Asymptomatic Bacteriuria in Pregnancy.  Commentary in the WHO Reproductive Health Library, Issue #5, 2002.

Chaiworapongsa T, Romero R, Tolosa JE, Yoshimatsu J, Espinoza J, Kim YM, Kim JC, Bujold E, Kalache K, Edwin S.  Elevated Monocyte Chemotactic Protein-1 in Amniotic Fluid is A Risk Factor for Pregnancy Loss.  J of Mat Fet and Neonat Med;12(3):159-64. 2002.

Stepanuk K, Tolosa JE, Lewis D, Myers V, Royds C, Sabogal JC, Librizzi R. Folic Acid Supplementation Use Among Women who Contact A teratology Information Service. Am J Obstet Gynecol 187(4):964-7. 2002.

Espinoza J, Romero R, Chaiworapongsa T, Edwin S, Rathnasabapathy C, Tolosa J,  Donnenfeld  A, Craparo F, Gomez R, Bujold E Lipopolysaccharide-binding protein in microbial invasion of the amniotic cavity and human parturition. J of Mat-Fet Neon Med 12(5):313-21, 2002.

Tolosa JE, Varona M, Carrasquilla G, Cardenas O, Torres C, Pardo D, Leiva MC Frumkin H  Descripción del Uso y Manejo de Plaguicidas en las Empresas de Flores  Afiliadas a ASOCOLFLORES (Report submitted to ASOCOLFLORES-Colombia, August 2002).

LS Widger (Bernard), A.K. Stark, B.W. Jafek. “The Head and Neck Examination.”  ENT Secrets, 2nd Ed.  Philadelphia: Hanley and Befus, Inc., 2001.

Segel, SY, Marder, SJ, Parry, S, Macones, GA: Fetal abdominal wall defects and mode of delivery: A systematic review.  Obstet Gynecol. 98:867-873, 2001.

Angus, SR, Segel, SY, Hsu, CD, Locksmith, GJ, Clark, P, Sammel, MD, Macones, GA, Strauss, JF III, Parry, S: Amniotic fluid matrix Metalloproteinase-8 indicates intra-amniotic infection.  Am J Obstet Gynecol. 185:1232-1238, 2001.

Segel, SY and Marder, SJ: The Female Reproductive System.  In:  Kreisel, et al (eds) The Surgical Review.  Philadelphia, Lippincott, Williams, and Wilkins, 2001.

Mäkikallio K, Vuolteenaho O, Jouppila P and Räsänen J. Umbilical artery N-terminal peptide of proatrial natriuretic peptide in hypertensive pregnancies and fetal acidemia during labor. Obstet Gynecol 97:23-28, 2001.

Odibo A, Berghella V, Reddy U, Tolosa JE, Wapner RJ.  Does Transvaginal Ultrasound of the Cervix Predict Premature, Preterm Rupture of Membranes in a High-Risk Population?  Ultrasound in Obstet Geneco18:233-227. 2001.

Huskins WC, Ba-Thike K, Festin MR, Limpongsanurak S, Lumbiganon P, Peedicayil A, Purwar M, Shenoy S, Goldmann DA, Tolosa JE.  An International Survey of Practice Variation in the Use of Antibiotic Prophylaxis in Cesarean Section.  Inter J Gynecol Obstet  73(2001) 141-45.

Greene RA, Tolosa J, Bologenese RJ  Third trimester Hemorrhage. In: Fetal and Neonatal Secrets, Eds: Spitzer A, Polin R. Hanley & Belfus, 2001.

Greene RA, Tolosa J, Bologenese RJ  Amniocentesis. In: Fetal and Neonatal Secrets, Eds: Spitzer A, Polin R. Hanley & Belfus, 2001.

Yusuf  K, Smith SD, Levy R, Schaiff  WT, Wyatt SM, Sadovsky Y, Nelson D. ThromboxaneA2 limits differentiation and enhances apoptosis of cultured human trophoblasts. Pediatr Res 50(2):203-209. 2001.

Mäkikallio K, Vuolteenaho O, Jouppila P and Räsänen J. Association of severe placental insufficiency and systemic venous pressure rise in the fetus with increased neonatal cardiac troponin-T levels. Am J Obstet Gynecol 183:726-731, 2000.

Abbasi S, Hirsch D, Davis J, Tolosa J, Stouffer N, Debbs R, Gerdes JS.  Effect of Single vs. Multiple Courses of Antenatal Corticosteroids on Neonatal and Maternal Outcome.  Am J Obstet Gynecol 182:1243-9. 2000.

LE Davis, AR Hohimer, M Morton. Myocardial blood flow and coronary reserve in chronically anemic fetal lambs. Am J Physiol 277R306-313,1999. 

Frias AE Jr, Li H, Keeney G, Podratz KC and Woodruff TK.  Preoperative serum level of Inhibin A is an independent prognostic factor for the survival of postmenopausal women with epithelial ovarian carcinoma.  Cancer 85:465-471. 1999

Macones, GA, Segel, SY, Stamilio, DM and Morgan, MA: Predicting delivery within 48 hours in women treated with parenteral tocolysis.  Obstet. Gynecol. 93:432-436, 1999.

Rasanen J, Debbs RH, Wood DC, Weiner S and Huhta JC. The effects of maternal indomethacin therapy on human fetal branch pulmonary arterial vascular impedance. Ultrasound Obstet Gynecol 13:112-116, 1999.

Macones, GA, Segel, SY, Stamilio, DM and Morgan, MA: Prediction of delivery among women with early preterm labor by means of clinical characteristics alone.  Am J Obstet Gynecol. 181:1414-1418, 1999.

Petraglia F, Gomez R, Luisi S, Gallinelli A, Tolosa JE, Stomati M, Romero R.  Increased Midtrimester Amniotic Fluid Activin-A: A Risk Factor for Subsequent Fetal Death.  Am J Obstet Gynecol 1999; 180(1):194-197.

Berghella V, Daly SF, Tolosa JE, DiVito MM, Chalmers R, Garg N, Bhullar A, Wapner RJ.  Prediction of Preterm Delivery with Transvaginal Ultrasound of the Cervix in High- Risk Pregnancies: Does Cerclage Prevent Prematurity?  Am J Obstet Gynecol 181(4):809-815.1999.

Leiva MC, Tolosa JE, Binotto CN, Weiner S, Huppert L, Denis AL, Huhta JC.  Fetal Cardiac Development and Hemodynamics in the First Trimester.  Ultra Obstet Gynecol 14:169-174. 1999.

C Martin, A Yu, Bjiang, LE Davis, D Kimberly, AR Hohimer, G Semenza. Cardiac hypertrophy in chronically anemic fetal sheep: increased vascularization is associated with increased myocardial expression of vascular endothelial growth factor and hypoxia inducible factor 1. Am J Ob Gyn 178:527,1998.

Rasanen J, Wood DC, Debbs RH, Cohen J, Weiner S and Huhta JC. Reactivity of the human fetal pulmonary circulation to maternal hyperoxygenation increases during the second half of pregnancy. A randomized study. Circulation 97:257-262, 1998.

Sylvester KG, Rasanen J, Kitano Y, Flake AW, Crombleholme TM and Adzick NS. Tracheal occlusion reverses the high impedance to flow in the fetal pulmonary circulation and normalizes its physiological response to oxygen at full term. J Pediatr Surg 33:1071-1075, 1998.

Jouppila P, Räsänen J, Alahuhta S and Jouppila R. The effect of drugs on the uteroplacental and fetal circulation. In: Textbook of perinatal medicine, Editor-in-chief: A Kurjak. Parthenon Publishing, 481-487, 1998.

Segel, SY and Morgan, MA: Response to Varicella Vaccination: Could It Have an Effect During Subsequent Pregnancy?  Collected Letters of the International Correspondence Society of OB/GYN, Vol 39, No 9, September 1998.

Tolosa JE, Antibiotic Treatment for Asymptomatic Bacteruria in Pregnancy.  Commentary in the WHO Reproductive Health Library, Issue #2, 1998.

Bernick B, Ufberg D, Nemiroff R, Donnenfeld A, Tolosa JE.  Success Rate of Cytogenetic Analysis at the Time of Second Trimester Dilation and Evacuation.  Am J Obstet Gynecol; 179:957-61. 1998.

Yeagley TJ, Tolosa JE, Bhutani VK.  Perinatal Bacterial Infection:  An Update.  Indian J Pediatr 65:841-848. 1998.

Rasanen J, Debbs RH, Wood DC, Weiner S, Weil SR and Huhta JC.  Human fetal right ventricular ejection force under abnormal loading conditions during the second half of pregnancy. Ultrasound Obstet Gynecol 10:325-332, 1997.

Rasanen J, Debbs RH and Huhta JC. Echocardiography in intrauterine growth restriction. Clinical Obstet Gynecol 40:796-803, 1997.

Berghella V, Tolosa JE, Kuhlman KA, Weiner S, Bolognese R, Wapner, R.  Cervical Ultrasonography Compared to Manual Examination as a Predictor of Preterm Delivery.  Am J Obstet Gynecol; 177(4):723-730. 1997

Davis LE, AR Hohimer, R Brace. Changes in left thoracic duct lymph flow during progressive anemia in the ovine fetus. Am J Obstet Gynecol. 174:1469, 1996.

Davis LE, AR Hohimer, GD Giraud, M Reller, M Morton. Right ventricular function in chronically anemic lambs. Am J Obstet Gynecol. 174:1289, 1996.

LL Woods, AR Hohimer, LE Davis. Renal hemodynamic responses to amino acids in the sheep fetus. Am J Physiol. R1226,1996.

Rasanen J, Huhta JC, Weiner S, Wood DC and Ludomirski A. Fetal  branch pulmonary arterial vascular impedance during the second half of pregnancy. Am J Obstet Gynecol 174: 1441-1449, 1996.

Pouta A, Rasanen J, Airaksinen KEJ, Vuolteenaho OJ and Laatikainen TJ. Changes in maternal heart dimensions and plasma atrial natriuretic peptide levels in the early puerperium of normal and pre-eclamptic pregnancies. Br J Obstet Gynaecol 103: 988-992, 1996.

Karinen J, Rasanen J, Alahuhta S, Jouppila R and Jouppila P. Maternal and uteroplacental haemodynamic state in preeclamptic patients during spinal anaesthesia for Caesarean section. Br J Anaesth 76: 616-620,  1996.

Rasanen J, Wood DC, Weiner S, Ludomirski A and Huhta JC. Role of the pulmonary circulation in the distribution of human fetal cardiac output during the second half of pregnancy. Circulation 94:1068-1073, 1996.

Khandelwal M, Rasanen J, Ludomirski A, Addonizio P and Reece EA. Evaluation of fetal and uterine hemodynamics during maternal cardiopulmonary bypass. Obstet Gynecol 88:667-671, 1996.

Mazor M, Ghezzi F, Cohen J, Hershkovitz R, Tolosa JE, Levy J, Leiberman JR, Glezerman M.  Maternal Plasma and Amniotic Fluid Dehydroepiandroshterone-sulfate Concentrations in Preterm Labor.  Arch Gynecol Obstet, 259(1):7-12. 1996.

Romero R, Munoz H, Gomez R, Parra M, Polanco M, Valverde V, Hasbun J, Garrido J, Ghezzi F, Mazor M, Tolosa JE, Mitchell M.Increase in Prostaglandin Bioavailability Precedes the Onset of Human Parturition.Protaglandins,Leukotrienes and Essential Fatty Acids,1996;54:187-191.

Tolosa JE, Ludomirsky A.  Doppler Ultrasound in Twins.  In:  Doppler Ultrasound in Obstetrics and Gynecology.  Copel JA, Reed KL (eds), Raven Press, NY, 1996.

Silberbach M, L Woods, R Hohimer, T Shiota, Y Matsuda, L Davis. Role of endogenous atrial natriuretic peptide in chronic anemia in the ovine fetus: effects of a non-peptide antagoninst for atrial natriuretic peptide receptor. Pediatr Res 38:722-728,1995.

Räsänen J and Jouppila P. Fetal cardiac function and ductus arteriosus during indomethacin and sulindac therapy for threatened preterm labor. A randomized study.Am J Obstet Gynecol 173: 20-25, 1995.

Jouppila P, Rasanen J, Alahuhta S and Jouppila R. Vasoactive drugs  Hypertension Pregn 14: 261-275, 1995.

Räsänen J and Jouppila P. Uterine and fetal hemodynamics and fetal cardiac function after atenolol and pindolol infusion. A randomized study. Eur J Obstet Gynecol Reprod Biol 62: 195-201, 1995.

Alahuhta S, Rasanen J, Jouppila P, Kangas-Saarela T, Jouppila R, Hollmen AI and Westerling P. Effects of epidural ropivacaine and bupivacaine for cesarean section on uteroplacental and fetal circulation. Anesthesiology 83: 23-32, 1995.

Karinen J, Rasanen J, Alahuhta S, Jouppila R and Jouppila P. Effect of crystalloid and colloid preloading on uteroplacental and maternal haemodynamic state during spinal anaesthesia for Caesarean section. Br J Anaesth 75: 531-535, 1995.

Cohen J, Ghezzi F, Romero R, Ghidini A, Mazor M, Tolosa JE, Goncalves L, Gomez R.  GRO (Alpha) in the Feto-Maternal and Amniotic Fluid Compartments during Pregnancy and Parturition.  Am J Repro Immun, 35:23-29. 1995

Mazor M, Cohen J, Romero R, Ghezzi F, Tolosa JE, Gomez R. Cytokines and Preterm Labor.  Cambridge University Press, NY.  Fetal and Maternal Medicine Review, 7:207-233. 1995

Mazor M, Cohen J, Romero R, Ghezzi F, Tolosa JE, Fuentes JD.  The Role of Interleukin-6 in Preterm and Term Labor.  Israel J Obstet Gynecol, 6:162-171. 1995.

Gomez R, Ghezzi F, Romero R, Munoz H, Tolosa JE, Rojas I.  Premature Labor and Intra-Amniotic Infection.  Clinical Aspect and Role of the Cytokines in Diagnosis and Pathophysiology.  Clinics in Perinatology; 22(2): 281-342. 1995

Davis LE, AR Hohimer and LL Woods:  Renal function during chronic anemia in the ovine fetus.  Am J Physiol (Regulatory & Integrative) 266:R1759-1764, 1994.

Silberbach M, DF Anderson, MD Reller and LE Davis:  Effect of atrial natriuretic peptide on vascular permeation in the ovine fetus.  Pediatr Res 35:555-559, 1994.

Räsänen J and Jouppila P. Does a paracervical block with bupivacaine change vascular resistance in uterine and umbilical arteries? J Perinat Med 22: 301-308, 1994.

Jouppila P, Räsänen J, Alahuhta S and Jouppila R. The effect of maternal vasoactive agents on uterine and fetal hemodynamics. In: Fetus as a Patient- Advances in Diagnosis and Therapy, Eds: A Kurjak and F Chervenak. Parthenon Publishing, 389-398, 1994.

Karinen J, Räsänen J, Paavilainen T, Alahuhta S, Jouppila R and Jouppila P. Uteroplacental and fetal haemodynamics and cardiac function of the fetus and newborn after crystalloid and colloid preloading for extradural caesarean section anaesthesia. Br J Anaesth 73: 751-757, 1994.

Räsänen J, Juntunen K and Jouppila P. Sikiön sydämen rytmihäiriöiden kliininen merkitys. Duodecim 110: 575-583, 1994.

Grisso JA, Strom BL, Cosmatos I, Tolosa JE, Main D, Carson J.  Diagnostic Ultrasound in Pregnancy and Low Birthweight.  Am J Perinat; 11(4): 297-301. 1994;

Giraud GD, MJ Morton, LE Davis, MS Paul and KL Thornburg: Estrogen-induced left ventricular chamber enlargement in the ewe. Am J Physiol (Endocrin & Metabol) 264:E490-496, 1993.

Alahuhta S, Räsänen J, Jouppila P, Jouppila R and Hollmen AI. Epidural sufentanil and bupivacaine for labor analgesia and the Doppler velocimetry of umbilical and uterine arteries. Anesthesiology 78: 231-236, 1993.

Alahuhta S, Räsänen J, Jouppila P, Jouppila R and Hollmen AI. Uteroplacental and fetal circulation during extradural bupivacaine-adrenaline and bupivacaine for caesarean section in hypertensive pregnancies with chronic fetal asphyxia. Br J Anaesth 71: 348-353, 1993.

Jouppila P, Mäkäräinen L, Räsänen J, Valkama M and Paavilainen T. Aggressive direct treatment of a fetus with supraventricular tachycardia and hydrops fetalis. Ultrasound Obstet Gynecol 3: 279-283, 1993.

Jouppila P and Räsänen J. Effect of labetalol infusion on uterine and fetal haemodynamics and fetal cardiac function. Eur J Obstet Gynecol Reprod Biol 51: 111-117, 1993.

Segel, SY, Tam, HC, Yesavage, J, and Yeo, G: Determining the effectiveness of DSMIII-R criteria for major depression when applied to Chinese elders.  Clinical Gerontologist 13:3-16, 1993.

Davis L, RR Magness and CR Rosenfeld:  Role of angiotensin II and a-adrenergic receptors during estrogen-induced vasodilation in ewes.  Am J Physiol  (Endocrin & Metabol) 263:E837-843, 1992.

Alahuhta S, Räsänen J, Jouppila P, Jouppila R and Hollmen AI. Ephedrine and phenylephrine for avoiding maternal hypotension due to spinal anaesthesia for caesarean section. Effects on uteroplacental and fetal haemodynamics Int J Obstet Anesth 1: 129-134, 1992.

Räsänen J and Kirkinen P. Early-diastolic blood flow velocity block in the umbilical artery and fetal cardiac valvular insufficiency. Case report. J Perinat Med 20: 345-349, 1992.

Räsänen J. Fetal heart and haemodynamics in risk pregnancies and their changes after maternal vasoactive agents. An ultrasonic study. Doctoral thesis. Acta Univ Oul. D 247, 1992.

Davis LE and AR Hohimer:  Hemodynamics and organ blood flow in fetal sheep subjected to chronic anemia.  Am J Physiol, 261:R1542-R1548, 1991.

Alahuhta S, Räsänen J, Jouppila R, Jouppila P, Kangas-Saarela T and Hollmen AI. Uteroplacental and fetal haemodynamics during extradural anaesthesia for caesarean section. Br J Anaesth 66: 319-323, 1991.

Räsänen J, Alahuhta S, Kangas-Saarela T, Jouppila R and Jouppila P. The effects of ephedrine and etilefrine on uterine and fetal blood flow and on fetal myocardial function during spinal anaesthesia for caesarean section. Int J Obstet Anesth 1: 3-8, 1991.

Alahuhta S, Räsänen J, Jouppila R, Jouppila P and Hollmen AI. Effects of extradural bupivacaine with adrenaline for caesarean section on uteroplacental and fetal circulation. Br J Anaesth 67: 678-682, 1991.

Davis LE, AR Hohimer, GD Giraud, MS Paul and MJ Morton:  Vascular pressure-volume relationships in pregnant and estrogen treated guinea pigs.  Am J Physiol 257:(26)R1205-R1211, 1990.

Räsänen J. The effects of ritodrine infusion on fetal myocardial function and fetal hemodynamics. Acta Obstet Gynecol Scand 69: 487-492, 1990.

Frumkin H, Tolosa JE.  Philadelphia Neighborhood Lead Study: Report of Lead Exposure Pilot Study.  Report to Agency for Toxic Substances and Disease Registry, September 1990, pp 105, 12 appendices).

Kirkinen P, Herva R, Räsänen J, Airaksinen J and Ikäheimo M. Documentation of paradoxical umbilical blood supply of an acardiac twin in the antepartum state. J Perinat Med 17: 63-66, 1989.

Räsänen J, Kirkinen P and Jouppila P. Right ventricular dysfunction in human fetal compromise. Am J Obstet Gynecol 161: 136-140, 1989.

Räsänen J, Kirkinen P and Jouppila P. Fetal aortic blood flow and echocardiographic findings in human pregnancy. Eur J Obstet Gynecol Reprod Biol 27: 115-124, 1988.

Räsänen J and Kirkinen P. Growth and function of human fetal heart in normal, hypertensive and diabetic pregnancy. Acta Obstet Gynecol Scand 66: 349-353,1987.

Kirkinen Pja Räsänen J. Sikiön sydämen kaikututkimus. Duodecim 102: 950-959,1986.