Vitamin C to Decrease the Effects of Smoking in Pregnancy on Infant Lung Function
Clinical trial seeking participants
Vitamin C to decrease the effects of smoking in pregnancy on infant lung function
IRB 6019 PI: Cynthia McEvoy, M.D.
The purpose of this study is to see if extra vitamin C (500 MG per day) may help the lungs of infants whose mothers smoked during pregnancy.
Trial status: open to enrollment
Why is this study being done?
Researchers at OHSU are interested in learning more about the effects of vitamin C on the lung function of infants whose mothers smoked during pregnancy. Infants born to mothers who smoked while pregnant have increased wheezing, respiratory tract infections and asthma. There is early data that vitamin C during pregnancy may help the baby’s lungs develop more normally and may reduce the occurrence of breathing problems during childhood.
Pregnant women who consent to the study will be randomized to either vitamin C or a placebo. They will be asked to take a study tablet once per day with the prenatal vitamin provided through the study. Participation in this trial lasts from 11 to 22 weeks gestation until the time when the child reaches 12 months of age. Samples collected during the study include blood, urine and hair. Noninvasive breathing tests will be done when the infant at 3 and 12 months of age. Research staff will call the family every month until the infant is 12 months old to document the occurrence of wheezing.
The purpose of this study
See if extra vitamin C (500 mg per day) may help the lungs of infants whose mothers smoked during pregnancy.
Who is eligible to participate?
- are less than 22 weeks pregnant
- Currently smoke
- Have a singleton gestation
What is the compensation for this study?
Up to $375
Who do I contact for more information?
To find out more information and to see if you may qualify to participate, contact Kristin Milner, the study coordinator for this trail, at: 503-494-5598, 971-404-8667, or email email@example.com.