Proteomic Assessment of Preterm Risk (PAPR)

Clinical Trial Seeking Participants

PAPR: Proteomic Assessment of Preterm Risk

IRB 8131 (PI: Leonardo Pereira, MD, MCR)

The Maternal Fetal Medicine Research Unit is participating in a study to learn more about a possible blood test for preterm delivery prediction. The study sponsor is Sera Prognostics, Inc.

Trial status

TEMPORARILY CLOSED TO ENROLLMENT

Why is this study being done?

The sponsor of this study is looking for proteins that are associated with pregnancy complications. The blood samples will be analyzed in the laboratory to determine whether there are differences in the protein markers of people with and without spontaneous preterm birth.

Reducing the risk of pregnancy complications is important to help improve the health of mothers and babies. If a pregnancy complication can be predicted early, there is a greater chance it can be prevented. The information and blood samples from this study will be used to help with the development of tests that may help in early prediction and prevention of pregnancy complications.

The first condition that the investigators will be looking at is premature delivery. These are babies born before the 37th week of pregnancy or less than 3 weeks before your due date. The investigators may also look for changes in your blood that can occur with other pregnancy complications such as preeclampsia (high blood pressure, swelling and protein in the urine) and intrauterine growth restriction (a fetus whose weight is below the 10th percentile for gestational age).

The purpose of this study is to determine:

Whether the experimental blood test can identify markers that can accurately predict spontaneous preterm birth (prior to 37 weeks 0 days gestation) in asymptomatic pregnant women.

Who is eligible to participate?

Women who are at least 18 years old with:

• A singleton pregnancy
• Pregnancy within one of three gestational age intervals: 17-22 weeks, 24 weeks, or 26-28 weeks

What is the compensation for this study?

Participants will receive a $10 Target gift card.

Who do I contact for additional information?

To find out more information and to learn if you are qualified to participate, email our Research Coordinator, Janice Snyder, at snyderja@ohsu.edu or call 503-418-4622.