Clinical Trials in Women's Health

Current Clinical Trials in Contraception and Birth Control

Are you a woman seeking a new, non-hormonal form of contraception?
The Women’s Health Research Unit is recruiting for a clinical research study evaluating an investigational new spermicide. To qualify, you should be between the ages of 18 and 35, in a monogamous sexual relationship with a male partner and in good general health. IRB #7320

Are you a woman seeking long term contraception?
The Women’s Health Research Unit is conducting an approximately 6 year study of an investigational type of intrauterine system (IUS). To qualify, you should be between the ages of 16 and 45, currently in a mutually monogamous relationship, and be in good general health. IRB #6008

NES/E2 Contraceptive Vaginal Ring Study
The purpose of this study is to determine the effect on the bleeding patterns of Nestorone (NES) and three doses of estradiol (E2) when delivered by a contraceptive vaginal ring that is used continuously for 6 months.  IRB #8297

Current Clinical Trials in Urogynecology

Evaluation of Treatment Method for Combined Pelvic Organ Prolapse and Urinary Incontinence
This study looks at whether the success rate of mid-urethral slings for incontinence is similar in patients with prolapse (undergoing laparoscopic sacrocolpoplexy) as those patients without prolapse. IRB #5302

Overactive Bladder Study
The Women’s Health Research Unit is conducting a study looking at how the brain controls the bladder. IRB #6005

Current Clinical Trials in Pregnancy and Infertility

Biomarkers in Maternal, Fetal, and Pediatric Health and Disease
The purpose of this research study is to understand the role of protein biomarkers in health and disease. We are looking for proteins produced by genes that are associated with different health and disease states of pregnancy.

CHIPS:  Control of Hypertension In Pregnancy Study
The purpose of this study is to determine if in pregnant patients with non-severe, non-proteinuric hypertension, “less tight” vs. “tight” hypertension control will increase or decrease the likelihood of pregnancy loss or high level of neonatal care for more than 48 hours. IRB #7104

Interested in contributing to Stem Cell research?
Oregon Health & Science University is recruiting women to donate eggs to a research study. The study is evaluating new techniques for creating embryonic stem cell lines. IRB #3892

NEXT: Non-invasive Chromosomal Examination of Trisomy Study
The purpose of this research study is to evaluate a experimental blood test that detects fetal DNA in a mother’s blood, and to compare the experimental blood test with standard prenatal screening tests for detecting pregnancies with normal chromosomes in the fetus and pregnancies with chromosome abnormalities in the fetus (like Down Syndrome). IRB #8098

Proteomic Assessment of Preterm Risk (PAPR)
The purpose of this research study is to collect blood specimens and clinical information from pregnant women without signs of preterm labor in order to develop a non-invasive test for the prediction of preterm delivery. IRB #8131

Recurrent Preterm Birth
The purpose of this study is to understand why some women are more likely to experience pre-term birth than others. Pregnant women with a history of only preterm birth(s) are eligible. There is no compensation for participants. IRB #3954

Current Clinical Trials in Menopause and Dysfunctional Uterine Bleeding

Do you suffer from uterine fibroids and have uterine bleeding?
The Women’s Health Research Unit is recruiting women for a clinical research study to determine the safety of the study drug, Elagolix, and how different doses of the drug work compared to placebo in reducing heavy uterine bleeding. To qualify, you should be pre-menopausal and age 20 or older. IRB #7812

Current Clinical Trials in Other Areas of Women's Health

Lipid Level Study
The purpose of this study is to help determine why young women with regular menstrual cycles are at a lower risk of heart disease than men and than women who have undergone menopause. IRB #8023

Preclinical Studies on Endometrial Xenografts
The purpose of this research is to study the endometrium (the lining tissue of the uterus) in a research laboratory to learn more about possible medical treatments for endometriosis, a painful condition in women. IRB #5108