Clinical Trials in Ob/Gyn and Women's Health

Current Clinical Trials in Contraception and Birth Control

Are you a woman seeking a new, non-hormonal form of contraception?
The Women’s Health Research Unit is recruiting for a clinical research study evaluating an investigational new spermicide. To qualify, you should be between the ages of 18 and 35, in a monogamous sexual relationship with a male partner and in good general health. IRB #7320

Levonorgestrel Butanoate Injection Study
Evaluating the pharmacokinetics and pharmacodynamic profile of a single injection of levonorgestrel butanoate (LB) for Female Contraception. Effects on endometrial thickness, ovarian follicular development, and ovulation rates will be measured. IRB #7477

New Type of Contraceptive Patch
The Women’s Health Research Unit is conducting a study to investigate a new type of contraceptive patch. We are focusing on women with a high Body Mass Index (“BMI” is the ratio of your weight to height). IRB #6527

Current Clinical Trials in Urogynecology

Evaluation of Treatment Method for Combined Pelvic Organ Prolapse and Urinary Incontinence
This study looks at whether the success rate of mid-urethral slings for incontinence is similar in patients with prolapse (undergoing laparoscopic sacrocolpoplexy) as those patients without prolapse. IRB #5302

Overactive Bladder Study
The Women’s Health Research Unit is conducting a study looking at how the brain controls the bladder. IRB #6005

Pregnancy and Pelvic Injury Clinical Trial
This study looks at features of a woman’s anatomy, musculature and nerves before and after delivering a first child, as well as how those are associated with the lacerations (tears or cuts) and the symptoms of incontinence that can happen as a result of childbirth. IRB #3196

Current Clinical Trials in Pregnancy and Infertility

Are you interested in contributing to research on mitochondrial disease?
Oregon Health & Science University is recruiting women to donate eggs to a research study. The study is evaluating new techniques for correcting mitochondrial gene mutations in eggs. IRB #6709

Biomarkers in Maternal, Fetal, and Pediatric Health and Disease
The purpose of this research study is to understand the role of protein biomarkers in health and disease. We are looking for proteins produced by genes that are associated with different health and disease states of pregnancy.

CHIPS:  Control of Hypertension In Pregnancy Study
The purpose of this study is to determine if in pregnant patients with non-severe, non-proteinuric hypertension, “less tight” vs. “tight” hypertension control will increase or decrease the likelihood of pregnancy loss or high level of neonatal care for more than 48 hours. IRB #7104

Interested in contributing to Stem Cell research?
Oregon Health & Science University is recruiting women to donate eggs to a research study. The study is evaluating new techniques for creating embryonic stem cell lines. IRB #3892

Pregnancy and Pelvic Injury Clinical Trial
This study looks at features of a woman’s anatomy, musculature and nerves before and after delivering a first child, as well as how those are associated with the lacerations (tears or cuts) and the symptoms of incontinence that can happen as a result of childbirth. IRB #3196

Recurrent Preterm Birth
The purpose of this study is to understand why some women are more likely to experience pre-term birth than others. Pregnant women with a history of only preterm birth(s) are eligible. There is no compensation for participants. IRB #3954

Current Clinical Trials in Menopause and Dysfunctional Uterine Bleeding

Do you suffer from uterine fibroids and have uterine bleeding?
The Women’s Health Research Unit is recruiting women for a clinical research study to determine the safety of the study drug, Elagolix, and how different doses of the drug work compared to placebo in reducing heavy uterine bleeding. To qualify, you should be pre-menopausal and age 20 or older. IRB #7812

Current Clinical Trials in Other Areas of Women's Health

Pain and Immunity Study
The Women’s Health Research Unit is conducting a study to learn more about how negative thoughts affect the immune system in women with chronic pain. IRB #4920

Preclinical Studies on Endometrial Xenografts
The purpose of this research is to study the endometrium (the lining tissue of the uterus) in a research laboratory to learn more about possible medical treatments for endometriosis, a painful condition in women. IRB #5108