Understanding the Role of Cervical Mucus as Birth Control

Understanding the role of cervical mucus as birth control

Clinical trial seeking participantsStudy Image_Cervical Mucus Website Sized

eIRB study # 11532, primary investigator: Leo Han, M.D.

The Women's Health Research Unit is conducting a study looking at how cervical mucus plays a role in pregnancy prevention.

Trial status: actively enrolling 



Why is this study being done?

We currently know many things about cervical mucus and how it changes throughout the menstrual cycle due to hormones. For example, we know that during a normal menstrual cycle, cervical mucus changes in response to two hormones that the ovaries make: estrogen and progesterone. We also know that many of the birth control methods women use thicken mucus and make it less likely for sperm to enter the uterus. We hope that using this knowledge, and the knowledge we gain from this study, we could potentially use the information to design new non-hormonal contraceptives that use thickening of the cervical mucus to prevent pregnancy. 

Purpose of this study

  • To help us determine how hormones impact the production of cervical mucus, a fluid secreted by the opening of the uterus, also called the cervix.
  • To study some of the cells in the cervix that produce mucus.


Women who are between the ages of 21 and 40 who:

  • Are in good general health
  • Have regular menstrual periods
  • Are not currently using any form of hormonal contraceptive (birth control pills, an intrauterine device (IUD), a contraceptive implant, or injections for birth control)


Qualified participants will be compensated up to $2,000 for time and travel for 19 study visits including 2 whole day (8 hour) and several half day (4 hour) visits over the course of 3.5 months at OHSU.

Who do I contact for additional information?

To find out more information and to learn if you are qualified to participate, fill out the online form (see the green box below), call the Women’s Health Research Unit's confidential recruitment line, or email us at .

Complete the online form or call 503-494-3666