OHSU

Biomarkers in Maternal, Fetal, and Pediatric Health and Disease

Clinical Trial Seeking Participants

Maternal Body Composition and Placental Function—A Pilot Study

IRB 7942 (PI: Nicole Marshall, MD, MCR)

We are conducting a study to learn more about maternal body fat and muscle during pregnancy and how body type affects the ability of the place to transport nutrients.

Trial Status:

Temporarily Closed to Enrollment

Why is this study being done?

Researchers at OHSU are interested in understanding more about the role of protein expression patterns in pregnancy. It is hoped that protein chip analysis of different biological fluids from patients with and without specific pregnancy or medical conditions may reveal biomarkers that can be used for diagnostic purposes.

Samples may consist of a number of different biological fluids, including blood, amniotic fluid, cervical vaginal fluid, cord blood, placental tissue, cerebrospinal fluid, stool, or urine. This study will analyze available samples for proteins associated with specific disease states. New profiles of multiple biomarker proteins are being examined for diagnostic or screening tests.

In addition, we are building a library of samples from a wide range of patients that can be used for future studies. The study is designed to include pregnant women, neonates, and children but currently we are focused on recruitment of women during pregnancy. Samples are only provided for the study when clinical collection is taking place, like a scheduled blood draw, speculum exam, or indicated amniocentesis.

The purpose of this study is to:

Understand more about the connections between certain proteins and conditions of pregnancy.

Who is eligible to participate?

Women who are pregnant

  • With clinical indication for sample collection
  • With parental consent if under 18 years old

What is the compensation for this study?

There is no compensation for this study.

Whom do I contact for more information?

To find out more information and to learn if you are qualified to participate, email our Research Coordinator, Monica Rincon, or call 503-494-8748.