Biomarkers in Maternal, Fetal, and Pediatric Health and Disease
Clinical Trial Seeking Participants
Biomarkers in Maternal, Fetal, and Pediatric Health and Disease
IRB 0139 (PI: Leonardo Pereira, M.D.)
The purpose of this study is to understand the role of protein biomarkers in health and disease. We are looking for proteins produced by genes that are associated with different health and disease states of pregnancy or pediatrics. All pregnant women and newborns are eligible. There is no compensation for participants.
Trial Status:
Open to Enrollment
Why is this study being done?
Researchers at OHSU are interested in understanding more about the role of protein expression patterns in pregnancy. It is hoped that protein chip analysis of different biological fluids from patients with and without specific pregnancy or medical conditions may reveal biomarkers that can be used for diagnostic purposes.
Samples may consist of a number of different biological fluids, including blood, amniotic fluid, cervical vaginal fluid, cord blood, placental tissue, cerebrospinal fluid, stool, or urine. This study will analyze available samples for proteins associated with specific disease states. New profiles of multiple biomarker proteins are being examined for diagnostic or screening tests.
In addition, we are building a library of samples from a wide range of patients that can be used for future studies. The study is designed to include pregnant women, neonates, and children but currently we are focused on recruitment of women during pregnancy. Samples are only provided for the study when clinical collection is taking place, like a scheduled blood draw, speculum exam, or indicated amniocentesis.
The purpose of this study is to:
Understand more about the connections between certain proteins and conditions of pregnancy.
Who is eligible to participate?
Women who are pregnant
- With clinical indication for sample collection
- With parental consent if under 18 years old
What is the compensation for this study?
There is no compensation for this study.
Whom do I contact for more information?
To find out more information and to learn if you are qualified to participate, email our Research Coordinator, Janice Snyder, at snyderja@ohsu.edu or call 503-418-4622.
