Pressure Dynamics in the Uterus

This is a research study comparing the pressure in the uterus in women with open or blocked fallopian tubes.

eIRB study # 11443, PI:  Eva Patil, MD

Trial Status: Actively enrolling  


Why is this study being done?

Female permanent contraception, or sterilization, is widely used and very effective. Some methods of permanent contraception require a confirmation test to prove the fallopian tubes are blocked, but this test can be expensive and inconvenient for women. This test is called a hystero-(uterus) salpingo-(fallopian tube) graphy (HSG), an X-ray test. During the HSG study, the doctor will place a speculum in the vagina to see the cervix (opening to the uterus) and then, after cleaning the area with an antiseptic, insert a catheter through the cervix into the uterine cavity. A catheter is a small tube through which the contrast media (or dye) is injected. The outside end of the catheter will be attached to a pressure monitor that will record the pressure inside your uterus during the procedure. First there will be saline (salt water) infused through the catheter into your uterus. This saline will then be removed and the procedure repeated with the dye. The dye outlines the uterus and fallopian tubes with fluoroscopy (an X-ray machine with a screen). The entire HSG study procedure should take less than 30 minutes.

Purpose of the study:

The purpose of this study is to learn about alternative ways to test if the fallopian tubes are blocked after permanent contraception.


  • Literate in English
  • Age 18-50
  • No history of infertility with current regular menstrual cycles occurring every 24-37 days
  • At least one full-term vaginal delivery
  • Not currently be pregnant
  • Willing to undergo intrauterine saline infusion followed by a single HSG procedure
  • Able to understand and sign an IRB-approved informed consent form
  • Willing to complete a pre-procedure questionnaire
  • Willing to attend the study visit at a radiology center in Lake Oswego
  • Women with permanent tubal blockage - i.e. who have had an Essure (or Adiana) procedure OR Healthy controls: woman who have NO known blockage in uterus or tubes


Up to $200.

Who do I contact for additional information?

To find out more information and to learn if you are qualified to participate, fill out the online form or call the Women’s Health Research Unit confidential recruitment line.

Complete the Online Form or call 503-494-3666, or email