Emergency Contraception and BMI
eIRB #16291, PI: Alison Edelman, MD, MPHThe Women's Health Research Unit is conducting a study to examine a higher dose of the emergency contraceptive pill containing levonorgestrel and its ability to prevent ovulation in women of higher BMI. This study will also compare how well emergency contraceptive pill containing ulipristal acetate works in women of varying BMIs.
Why is this study being done?
- To determine if a different dose of LNG-containing emergency contraception in women of higher BMI and weight prevents the ovary from releasing an egg (ovulation) better than the normal dose of LNG-containing emergency contraception.
- To compare drug levels and ovarian activity between women of higher and lower BMIs with UPA-containing emergency contraception and to test a different dose of UPA-containing emergency contraception in women of higher BMI.
Eligibility:Women who are between the ages of 18-35 who:
- Have normal menstrual cycles
- Have both a BMI of 30 mg/k2 or higher and a weight of 176 lbs or more.
- Are willing to use non-hormonal contraception during the study such as a condom or other barrier method
- Are not currently using a hormonal form of birth control
Even if you have a Copper-IUD or have had a Tubal Ligation, you may still qualify for this study.
There are two parts of this study. Qualified participants may be able to participate in both parts of the study and may be compensated up to $2,140 for time and travel. Study participation for both parts would last approximately 5 months and would include approximately 39 visits. Study visits are timed with the start of a woman's menstrual cycle and are concentrated during a 2 week time period in the beginning to middle of each menstrual cycle with gaps of time in between where no study visits would occur. Study visits may occur on weekends or holidays depending on participant's menstrual cycle.
If a participant only participates in the LNG-containing Emergency Contraceptive portion of the study, participation would last approximately 2 months and would include approximately visits. Participants will be compensated up to $620 for time and travel.
If a participant only participates in the UPA-containing Emergency Contraceptive portion of the study, participation would last approximately 4 months and the number of visits would be approximately 25 visits. Participants may be compensated up to $1,520 for time and travel.