Clinical Trials in Women's Health

Women's Health Research

OHSU is actively recruiting patients for the clinical trials in the women’s health topics listed below.

Current Clinical Trials in Contraception and Birth Control

Oral Contraception (Birth Control) Metabolism and Effectiveness
The purpose of this study is to see if weight and body composition can affect how well oral birth control can work in women. IRB #9569

Reducing bleeding with the contraceptive implant
The Women’s Health Research Unit is recruiting for a clinical research study evaluating if a drug can help reduce irregular bleeding in women who use the implant for contraception.

Ulipristal Acetate Oral Contraceptive Study
The purpose of this study is to learn more about an exciting new estrogen-free contraceptive pill containing ulipristal acetate (UPA).

Current Clinical Trials in Urogynecology

Evaluation of Treatment Method for Combined Pelvic Organ Prolapse and Urinary Incontinence
This study looks at whether the success rate of mid-urethral slings for incontinence is similar in patients with prolapse (undergoing laparoscopic sacrocolpoplexy) as those patients without prolapse. IRB #5302

Examining the brain's control systems in overactive bladder using mindful based approach
Researchers at the OHSU Center for Women’s Health are conducting studies to find out what role the brain plays in people suffering from overactive bladder. We hope to see how using a mindfulness based stress reduction technique may improve symptoms related to urine incontinence and if symptom improvement also includes changes in brain function using MRI and DTI brain imaging. IRB # 9405

Refractory Overactive Bladder: Sacral Neuromodulation v. Botulinum Toxin Assessment
This study looks at how BOTOX® injections into the bladder compares to InterStim® for the treatment of urge urinary incontinence in women. IRB #8190

Current Clinical Trials in Pregnancy and Infertility

Biomarkers in Maternal, Fetal, and Pediatric Health and Disease
The purpose of this research study is to understand the role of protein biomarkers in health and disease. We are looking for proteins produced by genes that are associated with different health and disease states of pregnancy. IRB #0139

PreNATUS: Prenatal Non-invasive Aneuploidy Testing Utilizing SNPs Study
The purpose of this research study is to develop a significantly less invasive, safer, and more accurate method of testing for genetic diseases in the fetus. The study will determine whether a new experimental test using blood samples from both parents can identify chromosomal abnormalities (such as Down syndrome) in the fetus. IRB #9017

Recurrent Preterm Birth
The purpose of this study is to understand why some women are more likely to experience pre-term birth than others. Pregnant women with a history of only preterm birth(s) are eligible. There is no compensation for participants. IRB #3954

Vitamin C to Decrease the Effects of Smoking in Pregnancy on Infant Lung Function
The purpose of this study is to see if extra vitamin C (500 MG per day) may help the lungs of infants whose mothers smoked during pregnancy. IRB #6019

Current Clinical Trials in Menopause

There are currently no clinical trials in this category available for enrollment. Please check back soon.

Clinical Trials in Dysfunctional Uterine Bleeding

There are currently no clinical trials in this category available for enrollment. Please check back soon.

Current Clinical Trials in Women's and Gynecologic Cancers 

In Partnership With Knight Cancer Institute

Find current trials involving ovarian, uterine and cervical cancers.

Current Clinical Trials in Other Areas of Women's Health

HIFU Study
The purpose of this study is to determine the safety and efficacy of MRI guided focused ultrasound (HIFU) for treating symptomatic uterine fibroids.

New type of treatment for pain associated with endometriosis
The purpose of the study is to determine the safety of Elagolix (the study drug) and how different doses of the study drug work compared to placebo in managing moderate to severe pain associated with endometriosis. IRB #8498

Pilot Study: Lipoic Acid and Omega-3 Fatty Acid for Alzheimer's Disease Prevention
The primary aim of the pilot study is to provide data that can be used to better determine sample size for the design of a larger clinical trial. The pilot will evaluate the effectiveness of Lipoic Acid (LA) plus Omega-3 fatty acids (Omega-3) on preventing Alzheimer's Disease (AD).

Preclinical Studies on Endometrial Xenografts
The purpose of this research is to study the endometrium (the lining tissue of the uterus) in a research laboratory to learn more about possible medical treatments for endometriosis, a painful condition in women. IRB #5108

We offer study opportunities in the areas of sterilization, continuous oral contraceptives, a new contraceptive ring, osteoporosis, low libido, the Human Papilloma Virus (genital wart virus), and hot flashes. Please call our confidential recruitment line at 503 494-3666 to learn more about these studies or to get on a wait list as a potential participant.

If you are interested in Women’s Health Research, but don’t see a study that pertains to you at present, we would encourage you to contact us in order to receive information on future studies.

The Women’s Health Research Unit researches health issues including, but not limited to, contraception, menopause, vaginal atrophy, urinary incontinence and abortion.


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