Clinical Trials in Women's Health

Women's Health Research

OHSU is actively recruiting patients for the clinical trials in the women’s health topics listed below.

Current Clinical Trials in Contraception and Birth Control

Combined Hormonal Contraception and Emergency Contraception Study
The purpose of this study is to determine if taking a birth control pill affects how well an emergency contraceptive pill, called Ulipristal Acetate (UPA), works. eIRB #11784, PI: Alison Edelman, MD

NES/E2 Contraceptive Ring
The purpose of this research study is to learn more about a new contraceptive vaginal ring. The study will help us better understand the best dose of estradiol for the ring and whether women see any effects of the ring in their menstrual cycle patterns.  eIRB # 15294, PI: Jeffrey Jensen, MD, MPH

Understanding the Role of Cervical Mucus as Birth Control
This study examines cervical mucus and its role in providing birth control. This study also seeks to learn how hormonal medications can mirror the mucus changes during your natural cycle. Data from this trial will, potentially, help us design new non-hormonal contraceptives that use thickening of cervical mucus to prevent pregnancy. eIRB #11532, PI: Leo Han, MD

Current Clinical Trials in Urogynecology

Overactive Bladder Study
The purpose of this research study is to determine if the urinary microbiome affects overactive bladder syndrome (OAB). Currently, not much is known about the cause of OAB; this study seeks to determine if bacteria in the urinary tract play a role in OAB. Rahel Nardos, MD; eIRB # 10729

Current Clinical Trials in Pregnancy and Infertility

Maternal Body Composition Regulates Placental Function and Fetal Growth
The purpose of this research study is to learn more about how a pregnant woman’s body type (amount of muscle and fat) and food choices affect the nutrients transported from the placenta to the baby. We want to learn how this impacts the baby’s growth through the first year of life, and see if there are differences in growth between male and female babies. eIRB# 11175, PI: Nicole Marshall, MD, MCR

Myo-inositol in Pregnancy
Purpose of the study is to learn if myo-inositol supplements (supplement in the B-vitamin family) affect your blood sugar and how your body processes food for energy. eIRB #15080, PI: Amy M. Valent, DO

Optimizing Management of the Second Stage of Labor (OMSS): A Multicenter Trial
The purpose of this study is to assess the effectiveness of immediate pushing at complete cervical dilation on the rate of spontaneous vaginal delivery and pelvic floor muscle injury in nulliparous women. eIRB# 10411, PI: Aaron Caughey, MD, PhD

Current Clinical Trials in Menopause

There are currently no clinical trials in this category available for enrollment. Please check back soon.

Clinical Trials in Menstruation

Period Pain Study
The purpose of this study is to understand if a new vaginal ring is safe and helpful in managing painful periods. eIRB #15490, PI: Jeffrey Jensen, MD, MPH

Current clinical trials in Women's and Gynecologic Cancers 

In partnership with the Knight Cancer Institute

Find current trials involving ovarian, uterine and cervical cancers

Current Clinical Trials in other areas of women’s health

Mindfulness-Based Group Cognitive Behavior Therapy for Women with Provoked Localized Vulvodynia
"Mindfulness-Based Group Cognitive Behavior Therapy for Women with Provoked Localized Vulvodynia (PLV)" is a study designed to learn more about the use of mindfulness based group cognitive behavior for PLV pain and anxiety. Participants will be randomized to one of two groups: mindfulness based cognitive behavior therapy or group education seminars. PI: Catherine Leclair, MD eIRB# 15221