Katie Schenning, M.D., M.P.H.
Department of Anesthesiology and Perioperative Medicine (APOM) and Neurology
Primary mentor: Joseph Quinn, M.D.
Mentors: Nabil Alkayed, M.D., Ph.D.; Ansgar Brambrink, M.D., Ph.D.; Jacob Raber, Ph.D.
Dr. Katie Schenning is an anesthesiologist who plans to investigate the interaction between general anesthesia and surgery, sex, genetic variables, and dementia in the aged. Her goal is to develop a translational research program by using her clinical knowledge to optimize preclinical models to best address sex differences in posteroperative outcomes, and to use these laboratory studies to inform clinical investigations.
Project title: Postoperative cognitive decline: role of sex and APOE4
Janne Boone-Heinonen, PhD, MPH
Assistant professor of epidemiology
Department of Public Health and Preventive Medicine
Primary mentor: Stephen Fortmann, M.D.
Mentors: Kent Thornburg, Ph.D.; Jackilen Shannon, Ph.D.; Dawn Peters, Ph.D.
Dr. Boone-Heinonen is an epidemiologist with an overarching interest in social, environmental, and biological factors drivers of obesity in diverse populations. In ongoing research, she investigates modifiable environmental and behavioral determinants of diet, physical activity, and obesity using complex analytic methods. She is currently developing expertise in biological drivers of obesity that arise in early life, with the goal of developing future research on the extent to which maternal effects on offspring health can be mitigated by healthy diet and physical activity.
Project title: Life course impacts on obesity: mitigating maternal effects on offspring health
Jing Xu, Ph.D.
Oregon National Primate Research Center
Primary mentor: Richard Stouffer, Ph.D.
Mentors: Mary Zelinski, Ph.D.; Betsy Ferguson, Ph.D.; Tanja Pejovic, M.D.
Dr. Xu is interested in studying the mechanisms and regulation of ovarian folliculogenesis, as well as endocrine/paracrine pathways that influence follicular development and oocyte maturation in primates. While performing basic research, translational efforts will be made on human in vitro follicle maturation that may offer a means to enhance fertility options for women, including female cancer patients. Dr. Xu's long-term goal is to build an independent program in biomedical research which can be translated to clinical use to improve or control fertility, and hence women's health.
Project title: Anti-Müllerian hormone in primate folliculogenesis and fertility preservation
Laura Newell, M.D.
Knight Cancer Institute
Division of Hematology/Medical Oncology
Primary mentor: Grover Bagby, M.D.
Mentors: Leonardo Pereira, M.D., M.C.R.; Jeffrey Tyner, Ph.D.; Irina Burd, M.D., Ph.D.
Dr. Newell is a hematologist and hematopoietic stem cell transplant physician interested in responses of the innate immune system and inflammatory cytokine signaling pathways. She is currently investigating the role of the innate immune system in driving pathologic inflammatory responses to viral infections during pregnancy that may contribute to excessive fetal and maternal morbidity and mortality. Her goal is to pursue clinical investigation of novel, targeted therapies specifically for women with viral infections and post-viral inflammatory complications during pregnancy.
Project title: PIGF enhances viral-induced innate immune inflammatory responses in human mononuclear phagocytes; a potential mechanism for virus related morbidity and mortality in pregnancy.