OHSU

Program Leadership

The leadership, Dr. Daniel Dorsa, PhD, and Dr. Jeanne-Marie Guise, MD, MPH, reflects the Oregon BIRCWH's vision for an interactive and cooperative approach to career development and research. Their distinct backgrounds and different career pathways - Dr. Dorsa in the area of basic science research and Dr. Guise in the area of clinical research - reflect the essential melding of backgrounds needed to catalyze outstanding interdisciplinary research. The unique juxtaposition of leadership styles and positions in the institution complement each other to expand the reach of women's health research and career development across OHSU.

Dan Dorsa, PhD

Dan Dorsa, PI
Principal Investigator

Dr. Dan Dorsa is Senior Vice President for Research and Principal Investigator for the BIRCWH program.

Dr. Dorsa received his PhD in Endocrinology and Physiology from the University of California and has been at OHSU since 2002. He administers and coordinates academic research at OHSU's three schools.

Dr. Dorsa has been an active NIH funded investigator for more than 30 years in endocrinology and women's health research. The Dorsa laboratory examines the cellular and molecular events which mediate the effects of estrogen on gene transcription in brain neurons and glia. Classical actions of estrogen involving nuclear hormone receptor dimerization and binding to consensus hormone response elements, as well as "cross-talk" with other protein kinase-dependent signal transduction pathways such as protein kinase A, and the mitogen activated protein kinases are studied. The lab also investigates the relative roles of estrogen receptor-subtypes (ERa and ERb) in these responses. The interest is in understanding membrane initiated events in neuroendocrine regulation, reproductive behavior, and neurotropic effects in the developing and aging brain.

Dr. Dorsa has trained numerous graduate students, postdoctoral fellows, and clinical fellows, including MD and PhD students. Dr. Dorsa recognizes the importance of mentorship in developing successful academic research careers. As such, he has worked with the BIRCWH program for many years serving as primary Mentor and Principal Investigator. He believes the BIRCWH program is a unique resource to OHSU and an exemplar for interdisciplinary science in women's health research.

Jeanne-Marie Guise, MD, MPH

Dr Guise
Co-Principal Investigator & Program Director

Dr. Jeanne-Marie Guise is Co-Principal Investigator and Program Director for the BIRCWH program.

Dr. Guise brings over 15 years of experience with K programs as a K12 and K08 scholar, BIRCWH mentor, BIRCWH program director, and study section reviewer for both individual and program K12 programs. She was one of OHSU's first NICHD WRHR K12 scholars, and was the first WRHR graduate to receive independent funding within the first 2 years of her K12 award. She is a successful independent investigator as PI, co-PI, or co-Investigator of federally-funded R01s and center grants and is dedicated to interdisciplinary research, research training, and leadership. Her own research promotes patient safety and interdisciplinary team science ranging from epidemiology and randomized clinical trials to information technology and simulation.

Dr. Guise is the Director of the State Obstetric and Pediatric Research Collaboration (STORC), Director of the Oregon Institute for Patient-Centered Comparative Effectiveness and Associate Director of the Scientific Resource Center (SRC) at the Portland VA Research Foundation. Through these roles she is able to facilitate connections for BIRCWH scholars, assist in dissemination of their results, and facilitate new programs for career development, research, and women's health on a broader institutional level.

 Research Team 

Senior Research Assistant 

Department of Medical Informatics and Clinical Epidemiology 

Mail Code: BICC 

Program Manager 

Department of Obstetrics & Gynecology 

Mail Code: L466 

 

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