Clinical trials are research studies in which people help doctors find ways to improve health and bone and joint care. Each study tries to answer scientific questions and to find better ways to prevent, diagnose or treat bone and joint disease or ailments.
The results of these research studies, called outcomes, give healthcare providers the data necessary to make advances and improvements in the way doctors treat.
NeoCart Phase III: A Randomized Comparison of NeoCart® to Microfracture for the Repair of Articular Cartilage Injuries in the Knee.
The purpose of the clinical trial is to evaluate the safety and efficacy of an investigational cartilage tissue implant, NeoCart®, compared to microfracture, the current standard of care procedure for the treatment of articular cartilage defects of the knee.
Key patient eligibility considerations:
- Able and willing to give informed consent
- Between 18-59 years old
- Knee pain and functional interruption indicative of Grade 3-4a defects of the femoral condyles and/or trochlea
- BMI <35 kg/m2
No previous microfracture of the defect
Closed to Enrollment:
- DeNovo NT Stratified Knee: A Stratified, Post-Market Study of DeNovo NT for Treatment of Femoral and Patellar Articular Cartilage Lesions of the Knee.
- KineSpring® SOAR Trial: Prospective, Multi-Center, Pilot Study to Evaluate Symptom Relief in Patients with Medial Knee Osteoarthritis (OA) Treated with the KineSpring® Knee Implant for Load Reduction.
- NeoCart Phase I: An open Label Phase 1 Study of NeoCart for use in Repair of Articular Cartilage Injuries.
- NeoCart Phase II: A Randomized Comparison of NeoCart® to Microfracture for the Repair of Articular Cartilage Injuries in the Knee
If you are interested in learning more about these research studies at the OHSU Orthopedics and Rehabilitation Department, or participating in a research study, please talk with your doctor.
Your participation in research studies may help us find a cure or new treatment.
If you would like to find out more, you may also contact our Research Program Office:
3181 SW Sam Jackson Park Road, OP31
Portland, OR 97239
Tel: 503 418-8678
Fax: 503 494-5050