Steiner Lab Members
Robert Steiner, MD, is vice chairman for pediatric research at Doernbecher Children's Hospital. He is also professor of Pediatrics, and Molecular and Medical Genetics at Oregon Health & Sciences University School of Medicine.
Steiner earned his medical degree at the University of Wisconsin Medical School. He completed his residency in pediatrics at the Children's Hospital Medical Center at the University of Cincinnati, and then completed a fellowship in medical genetics at Seattle's Children's Hospital and Regional Medical Center, University of Washington.
Steiner specializes in the treatment of inborn errors of metabolism and osteogenesis imperfecta, a genetic disorder characterized by bones that break easily. He is involved in clinical and translational research supported by the National Institutes of Health.
Among his areas of expertise is Smith-Lemli-Opitz Syndrome (SLOS). SLOS is caused by a defect in the final step in cholesterol synthesis and is characterized by distinctive facial features, small head size, intellectual disability or learning disabilities, and behavioral problems.
Steiner is a fellow of the American College of Medical Genetics and of the American Academy of Pediatrics. He is a member of numerous professional organizations, including the American Society of Human Genetics, the American Association for the Advancement of Science and the American Board of Medical Genetics. He has published more than 70 papers in nationally and internationally respected peer-reviewed journals.
Anuradha Pappu, PhD is a Research Assistant Professor in the Department of Medicine at Oregon Health and Science University. She earned her doctorate in Biochemistry from University of Bombay, India and had fellowships in lipid metabolism at Harvard University and University of California, San Diego. She joined the department of Medicine at OHSU as an NIH fellow. Her research interests are in the pathophysiology of metabolic lipid disorders (hypercholesterolemia, Smith-Lemli-Opitz syndrome, cerebrotendinous xanthomatosis) and evaluation of clinical options for treatment of these patients by diet and drugs.
Louise Merkens, PhD, completed her degree at the State University of New York-Upstate Medical Center where she worked with Drs Jay and Helen Tepperman on the effects of high fructose and glucose diets on triglyceride metabolism. Postdoctoral positions included the University of Rochester Medical Center studying perfused kidney lipid metabolism and function and Vanderbilt University researching placenta membrane fluidity. Professional experience has included DNA repair in Fanconi Anemia, in the Department of Medical and Molecular Genetics, at OHSU and cell surface DNA binding proteins, Department of Immunology, VA Medical Center. Dr. Merkens joined Dr. Steiner's lab in the summer of 2000 to direct the laboratory research in the genetic and biochemical analyses in children with Smith-Lemli-Opitz syndrome.