OHSU

Selected Publications

"Diagnostic and prognostic utility of a DNA hypermethylated gene signature in prostate cancer," PLoS ONE (Vol: 9, Issue: 3, ) - 2014

"Orteronel for the treatment of prostate cancer," Future Oncology (Vol: 10, Issue: 5, Page 803-811) - 2014

"Androgen Receptor Promotes Ligand-Independent Prostate Cancer Progression through c-Myc Upregulation," PLoS ONE (Vol: 8, Issue: 5, ) - 2013

"Immunohistochemical expression of ERG in the molecular epidemiology of fatal prostate cancer study," Prostate (Vol: 73, Issue: 13, Page 1371-1377) - 2013

"Ipilimumab alone or in combination with radiotherapy in metastatic castration-resistant prostate cancer: Results from an open-label, multicenter phase i/ii study," Annals of Oncology (Vol: 24, Issue: 7, Page 1813-1821) - 2013

"Targeted MET inhibition in castration-resistant prostate cancer: A randomized phase II study and biomarker analysis with rilotumumab plus mitoxantrone and prednisone," Clinical Cancer Research (Vol: 19, Issue: 1, Page 215-224) - 2013

"Targeted therapy in prostate cancer: is there hope beyond the androgen receptor?," Oncology (Williston Park, N.Y.) (Vol: 27, Issue: 7, Page 628, 630, 637-638) - 2013

"Targeted therapy in prostate cancer: Is there hope beyond the androgen receptor?," ONCOLOGY (United States) (Vol: 27, Issue: 7, ) - 2013

"C-reactive protein as an adverse prognostic marker for men with castration-resistant prostate cancer (CRPC): Confirmatory results," Urologic Oncology: Seminars and Original Investigations (Vol: 30, Issue: 1, Page 33-37) - 2012

"Distinct epigenetic mechanisms distinguish TMPRSS2-ERG fusion-positive and -negative prostate cancers," Cancer Discovery (Vol: 2, Issue: 11, Page 979-981) - 2012

"A DNA methylation microarray-based study identifies ERG as a gene commonly methylated in prostate cancer," Epigenetics (Vol: 6, Issue: 10, Page 1248-1256) - 2011

"A HIF-regulated VHL-PTP1B-Src signaling axis identifies a therapeutic target in renal cell carcinoma," Science Translational Medicine (Vol: 3, Issue: 85, ) - 2011

"An epigenetic road to genome instability," Science Translational Medicine (Vol: 3, Issue: 67, ) - 2011

"Androgen receptor antagonist prostate cancer therapy," Drugs of the Future (Vol: 36, Issue: 5, Page 371-376) - 2011

"JAK and Jumonji: Deadly playmates," Science Translational Medicine (Vol: 3, Issue: 64, ) - 2011

"A new "fix" for cancer," Science Translational Medicine (Vol: 2, Issue: 49, ) - 2010

"A phase II study of paclitaxel poliglumex in combination with transdermal estradiol for the treatment of metastatic castration-resistant prostate cancer after docetaxel chemotherapy," Anti-Cancer Drugs (Vol: 21, Issue: 4, Page 433-438) - 2010

"Abrogating angiogenesis just got EZier," Science Translational Medicine (Vol: 2, Issue: 46, ) - 2010

"An expanded tumor playing field," Science Translational Medicine (Vol: 2, Issue: 55, ) - 2010

"Anti-CTLA-4 antibody therapy associated autoimmune hypophysitis: Serious immune related adverse events across a spectrum of cancer subtypes," Pituitary (Vol: 13, Issue: 1, Page 29-38) - 2010

"Antitumour activity of MDV3100 in castration-resistant prostate cancer: A phase 1-2 study," The Lancet (Vol: 375, Issue: 9724, Page 1437-1446) - 2010

"DAMD to do better!," Science Translational Medicine (Vol: 2, Issue: 16, Page 16ec12) - 2010

"Drugging bugs to make chemotherapy safer," Science Translational Medicine (Vol: 2, Issue: 58, ) - 2010

"Emerging therapies in castrate-resistant prostate cancer," Current Urology Reports (Vol: 11, Issue: 3, Page 152-158) - 2010

"Epigenetic regulation of androgen receptor signaling in prostate cancer," Epigenetics (Vol: 5, Issue: 2, Page 100-104) - 2010

"Ez(H2) does it!," Science Translational Medicine (Vol: 2, Issue: 22, Page 22ec37) - 2010

"Giving tumors the silent treatment," Science Translational Medicine (Vol: 2, Issue: 25, Page 25ec50) - 2010

"Itraconazole: From histoplasmosis to hedgehog signaling," Science Translational Medicine (Vol: 2, Issue: 28, Page 28ec62) - 2010

"Precious metals," Science Translational Medicine (Vol: 2, Issue: 40, ) - 2010

"Reducing the UnSIRTainty of Alzheimer's disease," Science Translational Medicine (Vol: 2, Issue: 43, ) - 2010

"Sinking prostate cancer from under the sea," Science Translational Medicine (Vol: 2, Issue: 37, ) - 2010

"Taking out the trash," Science Translational Medicine (Vol: 2, Issue: 31, Page 31ec74) - 2010

"Thinking outside the box in prostate cancer," Science Translational Medicine (Vol: 2, Issue: 61, ) - 2010

"TMPRSS2-ERG, a mover and a shaker," Science Translational Medicine (Vol: 2, Issue: 34, ) - 2010

"Turning off the cancer switch," Science Translational Medicine (Vol: 2, Issue: 52, ) - 2010

"Sulforaphane destabilizes the androgen receptor in prostate cancer cells by inactivating histone deacetylase 6," Proceedings of the National Academy of Sciences of the United States of America (Vol: 106, Issue: 39, Page 16663-16668) - 2009

"Through the looking glass," Blood (Vol: 114, Issue: 16, Page 3363-3364) - 2009

"Effect of DNA Methylation on Identification of Aggressive Prostate Cancer," Urology (Vol: 72, Issue: 6, Page 1234-1239) - 2008

"hADA2a and hADA3: new players in beta-catenin signaling.," Cancer biology & therapy (Vol: 7, Issue: 1, Page 129-130) - 2008

"hADA2a and hADA3: New players in β-catenin signaling," Cancer Biology and Therapy (Vol: 7, Issue: 1, Page 131-132) - 2008

"Early use of chemotherapy in conjunction with radical prostatectomy," Clinical Prostate Cancer (Vol: 3, Issue: 3, Page 144-149) - 2004

"Surgery-associated factor VIII inhibitors in patients without hemophilia," American Journal of the Medical Sciences (Vol: 318, Issue: 5, Page 350-352) - 1999