Waldenstrom's macroglobulinemia is a rare chronic form of lymphoma that affects blood plasma cells. It mainly affects people 65 and older, and is most common in white men. Waldenstrom's is a slow-growing disease that spreads slowly and is easily controlled with treatment when diagnosed early.
As with other types of non-Hodgkin's lymphomas, the most effective treatment is chemotherapy, usually a combination of two or more drugs. In some cases, your plasma is removed and replaced in a procedure calledplasmapheresis. Younger patients may need a bone marrow transplant.