Myelofibrosis is a serious bone marrow disorder that disrupts the way your body normally producesblood cells. It leaves scars in your bone marrow, leading to severe anemia, weakness, fatigue and often an enlarged spleen and scar tissue on the liver. If you have serious symptoms or complications, treatment options include:

  • Blood transfusions
  • Androgen therapy
  • Chemotherapy- Hydroxyurea (Hydrea) is the most commonly used chemotherapy drug in treating myelofibrosis.
  • Radiation therapy- radiation may help a small number of people who have bone pain. It can also help reduce the size of the spleen, when surgical removal isn't an option.
  • Thalidomide with steroids