Cytogenetics & Fish
The cytogenetics laboratory encompasses chromosome analysis both by banding and fluorescent in situ hybridization (FISH) techniques. The lab performs comprehensive cytogenetics testing on a variety of tissue types, including amniotic fluid, chorionic villi, bone marrow, blood, products of conception, skin biopsies and tumors. Clinical indications for cytogenetic analysis include cancer, high risk pregnancy, dysmorphic features, heart defects, short stature, infertility, and recurrent pregnancy loss. The lab is an international reference lab for chromosomal breakage studies associated with instability syndromes (e.g. Fanconi anemia). The lab also performs array comparative genomic hybridization (aCGH) for postnatal evaluation of disorders such as autism, developmental delay and multiple congenital anomalies, and is developing arrays for prenatal evaluation and cancer.